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Topic Review
Hydrogels Classification
Hydrogels are attractive biomaterials with favorable characteristics due to their water uptake capacity. However, hydrogel properties are determined by the cross-linking degree and nature, the tacticity, and the crystallinity of the polymer. 
  • 1.4K
  • 08 Dec 2021
Topic Review
Carbon Fixation
Carbon fixation or сarbon assimilation is the process by which inorganic carbon (particularly in the form of carbon dioxide) is converted to organic compounds by living organisms. The compounds are then used to store energy and as structure for other biomolecules. Carbon is primarily fixed through photosynthesis, but some organisms use a process called chemosynthesis in the absence of sunlight. Organisms that grow by fixing carbon are called autotrophs, which include photoautotrophs (which use sunlight), and lithoautotrophs (which use inorganic oxidation). Heterotrophs are not themselves capable of carbon fixation but are able to grow by consuming the carbon fixed by autotrophs or other heterotrophs. "Fixed carbon", "reduced carbon", and "organic carbon" may all be used interchangeably to refer to various organic compounds.
  • 1.4K
  • 06 Dec 2022
Topic Review
Polymeric Nanocapsules
Polymer-based nanocapsules have been widely studied as a potential drug delivery system in recent years. Nanocapsules—as one of kind nanoparticle—provide a unique nanostructure, consisting of a liquid/solid core with a polymeric shell. This is of increasing interest in drug delivery applications. In this review, nanocapsules delivery systems studied in last decade are reviewed, along with nanocapsule formulation, characterizations of physical/chemical/biologic properties and applications. Furthermore, the challenges and opportunities of nanocapsules applications are also proposed.
  • 1.4K
  • 28 Oct 2020
Topic Review
Metal Oxide Nanoparticles
Metal oxide nanoparticles (NPs) have received a great deal of attention as potential theranostic agents. Despite extensive work on a wide variety of metal oxide NPs, few chemically active metal oxide NPs have received Food and Drug Administration (FDA) clearance. The clinical translation of metal oxide NP activity, which often looks so promising in preclinical studies, has not progressed as rapidly as one might expect. The lack of FDA approval for metal oxide NPs appears to be a consequence of the complex transformation of NP chemistry as any given NP passes through multiple extra- and intracellular environments and interacts with a variety of proteins and transport processes that may degrade or transform the chemical properties of the metal oxide NP. Moreover, the translational models frequently used to study these materials do not represent the final therapeutic environment well, and studies in reduced preparations have, all too frequently, predicted fundamentally different physico-chemical properties from the biological activity observed in intact organisms. Understanding the evolving pharmacology of metal oxide NPs as they interact with biological systems is critical to establish translational test systems that effectively predict future theranostic activity. 
  • 1.4K
  • 20 Apr 2021
Topic Review
Surface Modification of Bacterial Cellulose
The surface of bacterial cellulose was successively modified by copper and zinc oxide nanoparticles using direct current (DC) magnetron sputtering and radio frequency (RF) reactive sputter coating techniques. The target materials, copper and zinc, were 99.99% pure and used in the presence of argon (Ar) gas, while zinc nanoparticles were sputtered in the presence of oxygen gas to make zinc oxide nanoparticles. The as-prepared bacterial cellulose/copper/zinc oxide nanocomposite has good ultraviolet resistance, anti-static and antibacterial characteristics. The surface morphology and chemical compositionof the nanocomposite were examined by X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD) and energy-dispersive X-ray spectroscopic (EDS) techniques. The prepared bacterial cellulose/copper/zinc oxide nanocomposite illustrates excellent ultraviolet resistance (T.UVA%; 0.16 ± 0.02, T.UVB%; 0.07 ± 0.01, ultraviolet protection factor (UPF); 1850.33 ± 2.12), antistatic behavior (S.H.P; 51.50 ± 4.10, I.E. V; 349.33 ± 6.02) and antibacterial behavior (Escherichia coli; 98.45%, Staphylococcus aureus; 98.11%). Our nanocomposite prepared by sputter coating method could be a promising and effective candidate for ultraviolet resistance, antistatic and antibacterial in term of functional, technical, medical and in many daily life applications.  
  • 1.4K
  • 01 Nov 2020
Topic Review
Microneedle-mediated protein delivery
Microneedle (MN) patches, consisting of micro/miniature-sized needles, are a promising tool to perforate the stratum corneum and to release drugs and proteins into the dermis following a non-invasive route. 
  • 1.4K
  • 28 Oct 2020
Topic Review
Torsion-Resistant Nature-Inspired Structures
The complexity of torsional load, its three-dimensional nature, its combination with other stresses, and its disruptive impact make torsional failure prevention an ambitious goal. However, even if the problem has been addressed for decades, a deep and organized treatment is still lacking in the actual research landscape. For this reason, this review aims at presenting a methodical approach to address torsional issues starting from a punctual problem definition. Accidents and breaks due to torsion, which often occur in different engineering fields such as mechanical, biomedical, and civil industry are considered and critically compared. More in depth, the limitations of common-designed torsion-resistant structures (i.e., high complexity and increased weight) are highlighted, and emerge as a crucial point for a deeper nature-driven analysis of novel solutions. In this context, an accurate screening of torsion-resistant bio-inspired unit cells is presented, taking inspiration specifically from plants, that are often subjected to the torsional effect of winds. As future insights, the actual state of technology suggests an innovative transposition to the industry: these unit cells could be prominently implied to develop novel metamaterials that could be able to address the torsional issue with a multi-scale and tailored arrangement.
  • 1.4K
  • 09 Oct 2021
Topic Review
Determination of Steroids by High Performance Liquid Chromatography-Fluorescence
Steroids are compounds widely available in nature and synthesized for therapeutic and medical purposes. Although several analytical techniques are available for the quantification of steroids in clinical samples, their analysis is challenging due to their low levels and complex matrices. The efficiency and quick separation of the high performance liquid chromatography (HPLC) combined with the sensitivity, selectivity, simplicity, and cost-efficiency of fluorescence, make HPLC coupled to fluorescence detection (HPLC-FLD) an ideal tool for routine measurement and detection of steroids for clinical and medical applications.
  • 1.4K
  • 11 Apr 2022
Topic Review
5-Hydroxymethylfurfural (HMF)
HMF, an indispensable member of the furan-based platform compound, known as the “sleeping giant”, is a bridge between renewable biomass and industrial bulk chemicals. In recent years, the catalytic transformation of biomass to HMF has been widely studied and envisaged to be hopeful in achieving sustainable biorefineries. The synthesis of HMF from biomass requires the acid hydrolysis of biomass to hexose, and then dehydration of hexose, to obtain HMF. In the second step of dehydration, starting from ketohexose (fructose) is more efficient than starting from aldohexose (glucose).
  • 1.4K
  • 11 Oct 2021
Topic Review
Amazonian Bacuri (Platonia insignis Mart.)
Bacuri (Platonia insignis Mart) is a species from the Clusiaceae genus. Its fruit pulp is commonly used in South America in several food products, such as beverages, ice cream and candies. Only the pulp of the fruit is used, and the peels and seeds are considered waste from these industries.
  • 1.4K
  • 29 Mar 2022
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