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Topic Review
Biography
Topic Review
Applications of Transglutaminase
Stabilization and reusability of enzyme transglutaminase (TGM) are important goals for the enzymatic process since immobilizing TGM plays an important role in different technologies and industries. TGM can be used in many applications. Enzyme TGM gained much attention due mainly to its potential for industrial applications. In their earlier uses, TGMs focused mostly on the cheesemaking processes, mainly improving the characteristics of the cheese itself. Later on, beverage properties were being improved by decreasing viscosity and solubility increases, as well as reduction in yoghurt syneresis. Therefore, the majority of investigations of applying TGMs in different processes focused mostly on improving the functional properties of proteins that can be utilized to develop improved food ingredients, such as crosslinked milk powders and high-added food products. Such improvements were also possible due to the different immobilization techniques of TGM.
457
16 Aug 2023
Topic Review
Zirconia-Based Ceramics Reinforced by Carbon Nanotubes
The use of CNTs (carbon nanotubes) as a secondary phase in a zirconia matrix is motivated by their outstanding crack self-healing ability, the possibility to tailor the desired nano-structural properties, and their exceptional wear behavior. Therefore, a detailed investigation into CNT features has been provided. The debate of using the different Vickers indentation fracture toughness equations to estimate the resistance of crack propagation was critically reviewed according to crack characteristics.
312
16 Aug 2023
Topic Review
Near-Infrared-II Fluorophores for Spectra-Domain Multichannel Biosensing
The pathological process involves a range of intrinsic biochemical markers. The detection of multiple biological parameters is imperative for providing precise diagnostic information on diseases. In vivo multichannel fluorescence biosensing facilitates the acquisition of biochemical information at different levels, such as tissue, cellular, and molecular, with rapid feedback, high sensitivity, and high spatiotemporal resolution. The implementation of in vivo multichannel fluorescence biosensing requires a meticulous selection of nonoverlap excitation–emission wavelengths for the use of NIR-II fluorophores. To achieve simultaneous visualization/tracking of multiple analytes at the tissue or cellular level, fluorophores with varying excitation–emission properties are necessary to bind specific targets.
259
16 Aug 2023
Topic Review
Polymeric-Micelle-Based Delivery Systems for Nucleic Acids
Nucleic acids can modulate gene expression specifically. They are increasingly being utilized and show huge potential for the prevention or treatment of various diseases. However, the clinical translation of nucleic acids faces many challenges due to their rapid clearance after administration, low stability in physiological fluids and limited cellular uptake, which is associated with an inability to reach the intracellular target site and poor efficacy. For many years, tremendous efforts have been made to design appropriate delivery systems that enable the safe and effective delivery of nucleic acids at the target site to achieve high therapeutic outcomes. Among the different delivery platforms investigated, polymeric micelles have emerged as suitable delivery vehicles due to the versatility of their structures and the possibility to tailor their composition for overcoming extracellular and intracellular barriers, thus enhancing therapeutic efficacy. Many strategies, such as the addition of stimuli-sensitive groups or specific ligands, can be used to facilitate the delivery of various nucleic acids and improve targeting and accumulation at the site of action while protecting nucleic acids from degradation and promoting their cellular uptake. Furthermore, polymeric micelles can be used to deliver both chemotherapeutic drugs and nucleic acid therapeutics simultaneously to achieve synergistic combination treatment.
230
16 Aug 2023
Topic Review
Sustainable Fire-Resistant Polysaccharide-Based Composite Aerogels
Fire safety is a critical concern in various industries necessitating the development of sustainable and effective fire-resistant materials. Sustainable fire-resistant polysaccharide-based composite aerogels are regarded as an innovative solution in fire safety applications.
356
16 Aug 2023
Topic Review
Development of Active Layers for Efficient Photovoltaic Devices
Photovoltaics (PVs) has become one of the emerging alternatives to progressively supply/replace conventional energy sources, considering the potential exploitation of solar energy. Depending on the nature of the light harvester to influence on its light-absorption capability and the facility to produce electricity, different generations of solar devices have been fabricated. Early studies of organic molecules (dye sensitizers) with good absorption coefficients, going through metal chalcogenides and, lastly, the timely emergence of halide perovskites, have promoted the development of novel and low-cost solar cells with promising photoconversion efficiency (PCE), close to the well-established Si-based devices.
272
16 Aug 2023
Topic Review
Peptide-Based Gene Delivery Vectors
Gene therapy is the ultimate therapeutic technology for diseases related to gene abnormality. However, the use of DNA alone has serious problems, such as poor stability and difficulty in entering target cells. The development of a safe and efficient gene delivery system is the cornerstone of gene therapy. Of particular interest, multifunctional peptides are rationally designed as non-viral vectors for efficient gene delivery. As components of gene delivery vectors, these peptides play critically important roles in skeleton construction, the implementation of targeting strategies, cell membrane penetration, endosome rupture, and nuclear transport.
455
16 Aug 2023
Topic Review
Causes and Mechanisms of Supercapacitor Ag(e)ing and Degradation
The most prominent and highly visible advantage attributed to supercapacitors of any type and application, beyond their most notable feature of high current and power capability, is their high stability in terms of lifetime, number of possible charge/discharge cycles or other stability-related properties. Actual devices show more or less pronounced deterioration of performance parameters during time and use, they show ageing.
383
15 Aug 2023
Topic Review
Functionalization of ETL/Perovskite Interface
Perovskite solar cells (PSCs) have revolutionized the field of photovoltaics, achieving certified power conversion efficiencies reaching 26% at the laboratory scale. High performance, enhanced stability, and long lifetime are prerequisites for the industrialization and commercialization of this class of third-generation photovoltaic technology. The electron transport layer (ETL) plays a pivotal role in obtaining stable perovskite solar cells with a high power conversion efficiency (PCE). It must be characterized by high transparency to visible light, photostability, and compatibility with the perovskite used. Therefore, a thorough comprehension and optimization of the interaction between perovskite materials and TiO2 ETL underlayers, as well as a special focus on the behavior of the corresponding devices, are necessary.
276
15 Aug 2023
Topic Review
Hydrogen Permeation Test Methods of Polymer Liner Material
Type IV hydrogen storage cylinders comprise a polymer liner and offer advantages such as lightweight construction, high hydrogen storage density, and good fatigue performance. However, they are also characterized by higher hydrogen permeability. Consequently, it is crucial for the polymer liner material to exhibit excellent resistance to hydrogen permeation. International organizations have established relevant standards mandating hydrogen permeation tests for the liner material of type IV on-board hydrogen storage cylinders.
688
14 Aug 2023
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