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Topic Review
Proteomics for Studying Antibiotic Action
To design more efficient treatments against bacterial infections, detailed knowledge about the bacterial response to the commonly used antibiotics is required. Proteomics is a well-suited and powerful tool to study molecular response to antimicrobial compounds. Bacterial response profiling from system-level investigations could increase our understanding of bacterial adaptation, the mechanisms behind antibiotic resistance and tolerance development.
  • 1.8K
  • 03 Nov 2020
Topic Review
Commercial Polymeric Membrane for Gas Separation
CO2 has been highly emitted to the environment, with the distribution of 25% being from electricity and heat production, 24% from agriculture, forestry, and other land usages, 21% by industry, 14% from transportation, 10% by other energies, and 6% from building. CO2 removal from natural gas is needed due to issues such as corrosion, catalyst poisoning and its effects on lowering the heating value of fuel. Several mass-transfer technologies can be used for this purpose, namely, membrane, absorption, adsorption and cryogenic. Membrane-based separation methods are more energy-efficient than heat-driven separations. Membrane-based separation uses 90% less energy than its distillation counterpart.
  • 1.7K
  • 12 Jan 2022
Topic Review
Polymeric Surfactants
Polymeric surfactants are surfactant molecules that have a polymeric backbone, which can be made up of various repeating units. These surfactants have both hydrophilic and hydrophobic segments, which allows them to interact with both water and oil. Polymeric surfactants are used in a variety of industrial applications, such as in the production of paints, adhesives, and coatings. They can improve the stability and performance of these products by reducing the surface tension and promoting the dispersion of pigments and fillers. In addition, polymeric surfactants are also used in the formulation of personal care products, such as shampoos, conditioners, and body washes. They can help to improve the texture and feel of these products, as well as enhance their cleaning and conditioning properties. One of the key advantages of polymeric surfactants is their ability to form stable micelles in solution. These micelles are aggregates of surfactant molecules that form a spherical structure with the hydrophobic segments on the inside and the hydrophilic segments on the outside. This allows for efficient emulsification of oil and water, which is important in a variety of industrial processes. Polymeric surfactants are a versatile class of surfactants that offer several unique properties and advantages in various applications. They are commonly used as emulsifiers, stabilizers, and thickening agents, and have potential applications in areas such as agriculture, oil and gas, and papermaking. Polymeric surfactants are a diverse class of surfactants that can be classified based on their composition, molecular weight, and degree of polymerization. They offer a range of unique properties and advantages in various applications, including cosmetics, food and beverage products, pharmaceuticals, and agriculture.
  • 1.8K
  • 24 Mar 2023
Topic Review
High Pressure Macromolecular Crystallography
Since its introduction in the early 1970s, high pressure crystallography (HPX) has shown great potential for the investigation of different types of matter. Using diamond anvil cells, HPX is an emerging technique that has been rapidly implemented, making it available to biologists, and there is immense potential for utilizing this technique in biological systems in the future. At the molecular level, high-pressure crystallographic investigation provides information on structural characteristics that not only determine the native conformation of a protein but also the conformations with higher free-energy, thus revealing function-related structural changes and properties that can be modified as a result of pressurization. The increase in the number of crystal structures of different macromolecules determined under high pressure over the last five decades can be ascribed mainly to two factors: the emergence of high-pressure cells with very large, open angles, and the advent of third generation synchrotron sources. The use of high pressure crystallography as a research tool has been shown to contribute to the advancements in the basic fields of biochemistry (protein misfolding and aggregation), biophysics (protein stability), and biotechnology (food processing).
  • 1.7K
  • 04 Apr 2023
Topic Review
Biosensors for Malaria Biomarkers
This entry discusses recent advances in the development of biosensors for the purposes of malaria diagnostics. It underscore relevant challenges that have defined the gap between biosensor development and their successful utilization in routine clinical practice within resource-limitted settings. It proposes a way to think about developing biosensors that are suitable for biomedical diagnostics applications.
  • 1.7K
  • 30 Oct 2020
Topic Review
Atmospheric Pressure Plasma Surface Treatment
Atmospheric plasma treatment is an effective and economical surface treatment technique. The main advantage of this technique is that the bulk properties of the material remain unchanged while the surface properties and biocompatibility are enhanced.
  • 1.7K
  • 09 Apr 2021
Topic Review
Reaction of CO2 with Epoxides
Coupling of CO2 with epoxides is a green emerging alternative for the synthesis of cyclic organic carbonates (COC) and aliphatic polycarbonates (APC). The scope of this work is to provide a comprehensive overview of metal complexes having sulfur-containing ligands as homogeneous catalytic systems able to efficiently promote this transformation with a concise discussion of the most significant results. The crucial role of sulfur as the hemilabile ligand and its influence on the catalytic activity are highlighted as well.
  • 1.7K
  • 22 Jan 2021
Topic Review
Free Radical
Free radicals can be defined as molecular entities or molecular fragments, capable of independent existence (hence “free”). They contain one or more unpaired electrons in an outer atomic orbital or molecular orbital (hence “radical”). The negative electrical charge of electron(s) may be counterbalanced by the positive nuclear charge of positrons, resulting in a neutral particle; otherwise, having anion or cation radicals.
  • 1.7K
  • 29 Apr 2022
Topic Review
Extraction Functional Ingredients from Jackfruit
Various studies in the literature showed the effect of conventional and non-conventional extraction methods to obtain jackfruit functional ingredients; among the non-conventional methods, some use emerging technologies to extract or as a pre-treatment. Among the studies using conventional extraction, applying solvents such as methanoland oxalic acidstands out, as well as the extraction with hot water. Regarding extraction by emerging technologies, radio frequency-assistedand supercritical fluid (SFE) with CO2extractions have attracted attention owing to their less negative impact on the environment and safety of the final product obtained in comparison with other methods using non-conventional technologies.
  • 1.7K
  • 26 Aug 2021
Topic Review
Synthesis and Properties of Pyrazoles
Pyrazole derivatives are a special class of N-heterocyclic compounds (NHCps) bearing a heteroaromatic five-membered ring with two adjacent nitrogen atoms in the annular structure, one pyrrole-type (proton donor) and one pyridine-type (proton acceptor). Pyrazoles can act as weak bases or acids, with possible strength highly dependent on the nature of their substituent groups. The other three positions in the ring permit structural variants starting from the appropriate precursors or using post-functionalization reactions once the pyrazole ring is formed; these variations give the pyrazoles diverse and valuable synthetical, biological, and photophysical properties; indeed, more complex structures with various relevant examples can be formed from them.
  • 1.7K
  • 09 Sep 2022
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