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Topic Review
Biography
Topic Review
Applications of Heterocyclic NO-Donors
In a series of known structural classes capable of NO release, heterocyclic NO-donors are of special importance due to their increased hydrolytic stability and low toxicity. It is no wonder that synthetic and biochemical investigations of heterocyclic NO-donors have emerged significantly in recent years. In this review, we summarized recent advances in the synthesis, reactivity and biomedical applications of promising heterocyclic NO-donors (furoxans, sydnone imines, pyridazine dioxides, azasydnones).
713
28 Oct 2021
Topic Review
Nanocomposites for Electrochemical Sensors
The elevated concentrations of various trace metals beyond existing guideline recommendations in water bodies have promoted research on the development of various electrochemical nanosensors for the trace metals’ early detection. Inspired by the exciting physical and chemical properties of nanomaterials, advanced functional nanocomposites with improved sensitivity, sensitivity and stability, amongst other performance parameters, have been synthesized, characterized, and applied on the detection of various trace metals in water matrices.
713
18 Feb 2021
Topic Review
Cellulosic-Based Conductive Hydrogels for Electro-Active Tissues
The use of hydrogel in tissue engineering is not entirely new. In the last six decades, researchers have used hydrogel to develop artificial organs and tissue for the diagnosis of real-life problems and research purposes. Trial and error dominated the first forty years of tissue generation. Nowadays, biomaterials research is constantly progressing in the direction of new materials with expanded capabilities to better meet the current needs.
713
14 Mar 2022
Topic Review
Electrospun Scaffolds for Tissue Engineering
Electrospun fiber scaffolds offer distinct characteristics, including a high surface area-to-volume ratio, excellent porosity, fiber uniformity, compositional diversity, flexibility, and the ease of functionalization with bioactive molecules. These scaffolds can effectively control the release rate of bioactive molecules, making them promising candidates for delivering antibiotics, proteins, and growth factors.
713
08 Aug 2023
Topic Review
PZT
The ligand, 4'-(4-(2,2,2-tris(1H-pyrazol-1-yl)ethoxymethyl)phenyl)-2,2':6',2"-terpyridine (PZT) contains a terpyridine fragment and a tris(pyrazolyl) fragment, which may allow synthetic differentiation between the tridentate binding sites as a result of the meridional and the facial coordination preferences of these groups around the octahedral metal centres. This designed bridging ligand may offer the benefits of polydentate ligands and minimisation of isomeric possibilities. The tris(pyrazolyl)methane fragment is of interest, because the coordination chemistry of such systems has also been studied. It, too, is easy to prepare, by reaction of pyrazole with chloroform, and to derivatise, for example by reaction with formaldehyde, to give a molecule, 2,2,2-tris(1H-pyrazol-1-yl)ethanol, that can be readily joined to the other binding site, a terpyridine containing synthon.
713
10 Feb 2021
Topic Review
Silver Nanoparticles as Anti-Infectious Regents
Silver is easily available and known to have microbicidal effect with wide antibacterial spectrum due to its silver ions mainly; moreover, it does not impose any adverse effects on the human body. Furthermore, the development of multidrug-resistant bacteria, as in the case of antibiotics, is less likely. Recently, silver nanoparticles (Ag NPs) have been synthesized and revealed its anti-viral activity. Because of their characteristics, Ag NPs are useful countermeasures against infectious diseases, which constitute a major issue in the medical field. Therefore, Ag NPs could expect to apply to materials preventing healthcare workers (HCWs), not only patient, from various infection.
712
29 Oct 2020
Topic Review
Hybrid Nanobioengineered Nanomaterial-Based Electrochemical Biosensors
Nanobioengineered-based hybrid electrochemical biosensors exploit the synergistic properties of hybrid systems that connect biomolecules with nanomaterials to engineer highly sensitive biosensing platforms for the specific electrochemical detection of different target analytes.
712
30 Jun 2022
Topic Review
MSMPs and MSMs
Magnetic shape memory polymers (MSMPs) belong to the group of shape memory materials, a group that can change their shape back to their “remembered” shape when they are exposed to a stimulus. MSMPs are essentially shape memory polymers whose shape memory effect is stimulated by heat. In the case of the MSMPs, magnetic particles are incorporated in the shape memory polymer. When the material is placed in an external alternating magnetic field, the magnetic particles heat up due to induction heating. The heated particles heat the shape memory polymer from the inside and when the activation temperature is reached, the shape memory effect is activated. Magnetic soft materials (MSMs) exist out of an elastomer with incorporated magnetic particles. The magnetic fields of these magnetic particles are set in specific magnetization patterns inside the elastomer during the fabrication process. When the magnetic soft material is placed inside an external static magnetic field, the magnetic fields of the magnetic particles align with the external magnetic field. This creates micro torques in the elastomer and pulls the elastomer matrix in a programmed shape.
712
09 Oct 2021
Topic Review
Peppers Ethnopharmacology
Piper, Capsicum, and Pimenta are the main genera of peppers consumed worldwide. The traditional use of peppers by either ancient civilizations or modern societies has raised interest in their biological applications, including cytotoxic and antiproliferative effects.
712
02 Jun 2021
Topic Review
Design and Synthesis of Polyphosphodiesters
Polyacids containing –P(O)(OH)– fragment in the polymer backbone, or polyphosphodiesters (PPDEs), hold a special place among natural and synthetic polymers. The structural similarity of PPDEs to natural nucleic and teichoic acids, biocompatibility of PPDEs and their mimicking to biomolecules providing the ‘stealth effect’, high bone mineral affinity of PPDEs, and adjustable hydrolytic stability of PPDEs are the basis for various biomedical, industrial and household applications. Actual synthetic approaches to PPDEs are based on incredibly rich chemistry of organic phosphates and phosphonates, and include modern techniques such as catalytic ring-opening polymerization (ROP), acyclic diene metathesis (ADMET) polycondensation, and others.
711
09 Jan 2023
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