Topic Review
Inflammasome Regulation for IBD
Inflammasomes are multiprotein complexes formed to regulate the maturation of pro-inflammatory caspases, in response to intracellular or extracellular stimulants. Accumulating studies showed that the inflammasomes are implicated in the pathogenesis of inflammatory bowel disease (IBD), although their activation is not a decisive factor for the development of IBD. Inflammasomes and related cytokines play an important role in the maintenance of gut immune homeostasis, while its overactivation might induce excess immune responses and consequently cause tissue damage in the gut. Emerging studies provide evidence that some genetic abnormalities might induce enhanced NLRP3 inflammasome activation and cause colitis. In these cases, the colonic inflammation can be ameliorated by blocking NLRP3 activation or its downstream cytokine IL-1β. A number of natural products were shown to play a role in preventing colon inflammation in various experimental colitis models. On the other hand, lack of inflammasome function also causes intestinal abnormalities.
  • 653
  • 21 Apr 2021
Topic Review
Adsorbents for Heavy Metal Decontamination
The adsorption isotherm model is a valuable method for determining the theoretical optimal adsorption power as well as the potential interactions between adsorbents and adsorbate. Sorption isotherms are mathematical models that illustrate the allocation of metals in between adsorbate and adsorbent. The distribution of metals in between adsorbate and adsorbent depends upon the nature of the adsorbent whether it is homogeneous or heterogeneous, the type of exposure, and the bonding between adsorbent and adsorbate.
  • 653
  • 25 Aug 2021
Topic Review
Synthesis of Perovskite Nanowires
Metal halide perovskites are promising energy materials because of their high absorption coefficients, long carrier lifetimes, strong photoluminescence, and low cost. Low-dimensional halide perovskites, especially one-dimensional (1D) halide perovskite nanowires (NWs), have become a hot research topic in optoelectronics owing to their excellent optoelectronic properties. 
  • 653
  • 31 Jan 2023
Topic Review
Directed Assembly of Particle-Polymer Composites
Particle-polymer dispersions are ubiquitous in additive manufacturing (AM), where they are used as inks to create composite materials with applications to wearable sensors, energy storage materials, and actuation elements. It has been observed that directional alignment of the particle phase in the polymer dispersion can imbue the resulting composite material with enhanced mechanical, electrical, thermal or optical properties. 
  • 652
  • 17 Aug 2021
Topic Review
On-Demand Drug Delivery Systems Using Nanofibers
On-demand drug-delivery systems using nanofibers are extensively applicable for customized drug release based on target location and timing to achieve the desired therapeutic effects. A nanofiber formulation is typically created for a certain medication and changing the drug may have a significant impact on the release kinetics from the same delivery system. Nanofibers have several distinguishing features and properties, including the ease with which they may be manufactured, the variety of materials appropriate for processing into fibers, a large surface area, and a complex pore structure. Nanofibers with effective drug-loading capabilities, controllable release, and high stability have gained the interest of researchers owing to their potential applications in on-demand drug delivery systems.
  • 652
  • 29 Mar 2022
Topic Review
Lead Halide Perovskites Opto-Electronic Devices
In Lead Halide Perovskites Opto-Electronic Devices, we will discuss the development in the LHP-based functional devices in recent years. After a brief presentation of the LHP's properties, we will focus on the functional devices including lasers, photodetectors, and modulators. Then the fabrication of the LHP-based devices will be presented, which is followed by the summary and outlook.
  • 651
  • 29 Apr 2021
Topic Review
Dendrimers for Infectious Diseases
Functionalized and modified dendrimer platforms are capable of precise imaging and efficient treatment of tumors, providing solutions for combined monitoring and early treatment of cancers.
  • 651
  • 05 Jul 2021
Topic Review
Properties of Multi-Dimensional Biological Models with Cross-Scale Features
The rise in structural performance requirements in engineering is driving the research and development of stronger, stiffer, and lighter materials. However, most traditional artificial materials are unable to meet the needs of modern industrial and technological development. In fact, multifarious creatures in nature are further ahead in their use of structural materials. There is a fairly limited selection of natural structural materials at ambient temperatures. They usually consist of hard and soft phases arranged in a complex hierarchy with characteristic dimensions ranging from nanoscale to macroscale. The resulting materials usually show a nearly perfect combination of strength and toughness integrated with lightweight characteristics. This is exactly what is required of engineering materials.
  • 651
  • 12 Nov 2021
Topic Review
Functional Materials for Wastewater Treatment
Functional materials play a central role in the advancement of these technologies due to their highly tunable properties and functions. 
  • 651
  • 27 Apr 2022
Topic Review
Photoresponsive Supramolecular Systems
Photosensitive supramolecular systems have garnered attention due to their potential to catalyze highly specific tasks through structural changes triggered by a light stimulus. The tunability of their chemical structure and charge transfer properties provides opportunities for designing and developing smart materials for multidisciplinary applications. Photoswitchable systems designed to catalyze chemical reactions must incorporate the appropriate photochromic units into the system to translate the structural switching states into a different chemical reactivity. 
  • 651
  • 01 Aug 2022
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