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Topic Review
LACE Index Predicts High Risk of 30-Day Readmission
The LACE index accounts for: Length of stay (L), Acuity of admission (A), Comorbidities (C), and recent Emergency department use (E).  The incorporation of a high-risk LACE index showed favorable risk prediction and could be applied to predict 30-day readmission with chronic conditions. 
  • 1.1K
  • 12 May 2022
Topic Review
Antioxidants for Patients with Fibromyalgia
Fibromyalgia (FM) is a syndrome characterized by chronic widespread pain. Pain is the predominant symptom; allodynia and hyperalgesia are also frequent. These patients also present severe fatigue, impaired cognition, and sleep disturbance, among others. In recent years, antioxidant supplements have become popular to counteract the effects of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. 
  • 1.9K
  • 12 May 2022
Topic Review
Decrease Death Rate of Neonates
Neglected diseases still kill and disable too many, but no age group has in this regard received less attention than newborns. A newborn or neonate is a human from age 0 to 28 days. Worldwide, their contribution to death and disease is overwhelming and unequaled by any condition, while at the same time, its prevention and treatments are simple, relatively cheap, and efficient. 
  • 286
  • 12 May 2022
Topic Review
Detraining in Athletes and COVID-19
The COVID-19 pandemic has affected many people in general and athletes in particular. This has led to a series of restrictions, which from a pathophysiological point of view, may affect the athlete’s performance in the short and long term. The restrictions basically affect training and eating habits, disturbing physical condition, as well as psychological behavior and general health status. Several aspects of systemic alterations caused by the SARS-CoV-2 virus and the resultant COVID-19 disease have been currently explored in the general population. Researchers believe that the most important element to take into account is the neuromuscular aspect, due to the implications that this system entails in motion execution and coordination. In this context, deficient neuromuscular control when performing dynamic actions can be an important risk factor for injury. 
  • 385
  • 11 May 2022
Topic Review
Management of Advanced Aged Patients with Rib Fractures
Rib fractures are painful and disabling injuries found in chest trauma patients. Elderly patients (age > 60 years old) represent the majority of the victims of major trauma, and rib fractures account for 10% of all trauma admissions. Rib fracture management includes operative and non-operative approaches. Conservative treatment generally consists of satisfactory pain control, respiratory assistance, cough strategies, and deep breathing exercises. Surgical fixation in elderly patients seems to result in better outcomes than conservative treatment in terms of shorter hospitalization time, more favorable pain feedback and reduced associated morbidity. 
  • 448
  • 11 May 2022
Topic Review
Evolution of Antimicrobial Resistance
Neisseria gonorrhoeae has become a significant global public health problem due to growing infection rates and antibiotic resistance development. In 2012, N. gonorrhoeae positive samples isolated from Southeast Asia were reported to be the first strains showing resistance to all first-line antibiotics. To date, N. gonorrhoeae’s antimicrobial resistance has since been identified against a wide range of antimicrobial drugs globally. Hence, the World Health Organization (WHO) listed N. gonorrhoeae’s drug resistance as high-priority, necessitating novel therapy development. The persistence of N. gonorrhoeae infections globally underlines the need to better understand the molecular basis of N. gonorrhoeae infection, growing antibiotic resistance, and treatment difficulties in underdeveloped countries.
  • 323
  • 11 May 2022
Topic Review
Dry Needling in Chronic Neck Pain
Chronic Neck Pain (CNP) is one of the main causes of disability worldwide, and it is necessary to promote new strategies of therapeutic approach in the treatment of chronic pain. Dry needling (DN) is defined as an invasive physiotherapy technique used in the treatment of neuromusculoskeletal disorders. 
  • 643
  • 11 May 2022
Topic Review
Transcranial Direct Current Stimulation on Post-Stroke Dysphagia
Dysphagia is one of the most common symptoms in patients after stroke onset, which has multiple unfavorable effects on quality of life and functional recovery. Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation that is widely used to improve deglutition function. Recently, some studies have confirmed that tDCS enhances deglutition function after stroke.
  • 412
  • 10 May 2022
Topic Review
Health, Economic and Social Challenges in COVID-19 Pandemic
The COVID-19-pandemic-related health, economic and social crises are leading to huge challenges for all spheres of human life across the globe. Various challenges highlighted by this pandemic include, but are not limited to, the need for global health cooperation and security, better crisis management, coordinated funding in public health emergencies, and access to measures related to prevention, treatment, and control. 
  • 863
  • 10 May 2022
Topic Review
The Role of Vitamin K in Humans
As human life expectancy is rising, the incidence of age-associated diseases will also increase. Scientific evidence has revealed that healthy diets, including good fats, vitamins, minerals, or polyphenolics, could have antioxidant and anti-inflammatory activities, with antiaging effects. Recent studies demonstrated that vitamin K is a vital cofactor in activating several proteins, which act against age-related syndromes. Thus, vitamin K can carboxylate osteocalcin (a protein capable of transporting and fixing calcium in bone), activate matrix Gla protein (an inhibitor of vascular calcification and cardiovascular events) and carboxylate Gas6 protein (involved in brain physiology and a cognitive decline and neurodegenerative disease inhibitor). 
  • 639
  • 07 May 2022
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