Topic Review
Monosodium Crystals in Vessels of Patients with Gout
Cardiovascular disease in gout is a central issue, but the underlying mechanisms linking the two are unclear. The existence of monosodium (MSU) crystal deposition directly inflaming vessel walls has been recurrently suggested and challenged since the 1950s and is again a matter of active debate since recent studies using dual-energy computed tomography (DECT) suggested a higher prevalence of plaques considered to be containing MSU crystals in patients with gout.
  • 234
  • 07 Dec 2023
Topic Review
Health Benefits and Detrimental Effects of Wine Consumption
Wine contains a large quantity of several phenolic compounds and this distinguishes it from other alcoholic beverages, while several microbiota metabolites that are formed after wine consumption by digestion of all wine polyphenols (except stilbenes), further increase the diversity of bioactive phenolic compounds.
  • 234
  • 13 Oct 2023
Topic Review
Role of Muscle Biomarkers in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is the predominant orthopedic disorder in children, affecting 1–3% of the global population. Research in this field has tried to delineate the genetic factors behind scoliosis and its association with heredity since AIS is considered a polygenic disease and has different genetic and epigenetic factors. 
  • 233
  • 29 Dec 2023
Topic Review
Associations between Childhood Abuse and Adult Psychopathology
Research consistently shows that abuse during childhood is related to adult psychopathology. Adverse childhood experiences, including emotional, physical, and sexual abuse, have been consistently linked to mental health problems in children and adults.
  • 233
  • 05 Mar 2024
Topic Review
Fitness Costs Antibiotic Resistance in the Gut
The acquisition of antibiotic resistance by horizontal gene transfer and by mutational changes in the chromosome or genes located in mobile genetic elements, followed by antibiotic resistance phenotype expression, implies modification of the cellular physiological status, including homeostatic adaptations of the previously susceptible cell.
  • 232
  • 26 Feb 2024
Topic Review
Weight Management on the Level of Primary Healthcare
Obesity is a complex disease that, like COVID-19, has reached pandemic proportions. Consequently, it has become a rapidly growing scientific field, represented by an extensive body of research publications.
  • 231
  • 26 Dec 2023
Topic Review
Evacuation Solutions for Individuals with Functional Limitations
The built environment continues to become increasingly accessible to people with disabilities, yet there remains a lack of focus on how these individuals are evacuated in emergencies. Studies highlight the importance of tailoring solutions to the needs of individuals with different functional limitations. There are six main evacuation solution types: notification, wayfinding, egress, building design, strategy, and training programs. 
  • 230
  • 31 Jan 2024
Topic Review
Opioid Stigma in Cancer Settings
Cancer-related pain affects a majority of patients with advanced cancer and is often undertreated. The treatment of this pain is largely reliant on the use of opioids, which are essential medicines for symptom management and the maintenance of quality of life (QoL) for patients with advanced cancer. While there are cancer-specific guidelines for the treatment of pain, widespread publication and policy changes in response to the opioid epidemic have drastically impacted perceptions of opioid use leading to stigmatization. 
  • 229
  • 20 Jul 2023
Topic Review
Efficacy and Enterococcal Consumption
Enterococci are often used in probiotics but can also cause nosocomial infections. As such, enterococcal consumption may have beneficial health effects, but a thorough evaluation of virulence absence and risk of antibiotic resistance spread is needed at the strain level. 
  • 228
  • 23 Aug 2023
Topic Review
Clinical Reasoning and Clinical Decision-Making Systems
Due to COVID period many people have become recreational runners. Recreational running is a regular way to keep active and healthy at any age. Additionally, running is a popular physical exercise that offers numerous health advantages. However, recreational runners report a high incidence of musculoskeletal injuries due to running. The proposed intelligent system uses data mining algorithms for the rehabilitation guidance of recreational runners with musculoskeletal discomfort. The system classifies recreational runners based on a questionnaire that has been built according to the severity, irritability, nature, stage, and stability model and advise them on the appropriate treatment plan/exercises to follow. 
  • 226
  • 24 Nov 2023
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