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Topic Review
Transmastoid Superior Semicircular Canal Plugging for SSCD
The transmastoid plugging of a superior semicircular canal is considered a safe and effective technique for the management of superior semicircular canal dehiscence (SSCD). 
  • 294
  • 20 Oct 2023
Topic Review
The Health of Healthcare Professionals in Oncology
From the analysis of the scientific literature relating to the health of oncological patients, the need to consider the global dimension of health of individuals emerges, which subsumes the bodily dimension and involves all the actors who offer their contribution to it in different ways. In this direction, the state of the art of the health construct offered by healthcare professionals highlights a lack of scientific contributions to the specific subject although these professionals are fundamental figures in oncological diagnosis setups. A in the oncological field studied the competencies of patients and caregivers in the management of the implications of surgery: it emerged that oncological treatments have effects on all aspects of life; thus, the roles in an oncological situation need to develop new competencies in order to preserve life quality.
  • 293
  • 25 May 2022
Topic Review
Urgent Threat of Infections by Antimicrobial Resistant Bacteria
Infectious disease outbreaks have caused thousands of deaths and hospitalizations, along with severe negative global economic impacts. Among these, infections caused by antimicrobial-resistant microorganisms are a major growing concern. The misuse and overuse of antimicrobials have resulted in the emergence of antimicrobial resistance (AMR) worldwide. Carbapenem-resistant Enterobacterales (CRE) are among the bacteria that need urgent attention globally. The emergence and spread of carbapenem-resistant bacteria are mainly due to the rapid dissemination of genes that encode carbapenemases through horizontal gene transfer (HGT). The rapid dissemination enables the development of host colonization and infection cases in humans who do not use the antibiotic (carbapenem) or those who are hospitalized but interacting with environments and hosts colonized with carbapenemase-producing (CP) bacteria. There are continuing efforts to characterize and differentiate carbapenem-resistant bacteria from susceptible bacteria to allow for the appropriate diagnosis, treatment, prevention, and control of infections.
  • 293
  • 04 Jul 2023
Topic Review
Augmented Reality in Neurosurgery
Augmented reality (AR) involves the overlay of computer-generated images onto the user’s real-world visual field to modify or enhance the user’s visual experience. With respect to neurosurgery, AR integrates preoperative and intraoperative imaging data to create an enriched surgical experience that has been shown to improve surgical planning, refine neuronavigation, and reduce operation time. In addition, AR has the potential to serve as a valuable training tool for neurosurgeons in a way that minimizes patient risk while facilitating comprehensive training opportunities.
  • 293
  • 09 Oct 2023
Topic Review
Preterm Birth and Exposure to Endocrine Disrupting Chemicals
Endocrine disrupting chemicals (EDCs) are defined by the Endocrine Society as “exogenous chemicals, or mixtures of chemicals, that interfere with any aspect of hormone action.” They are often widely present in many communities and can alter various hormonal processes in the body.  Preterm birth (PTB) is a problem of international concern, as it is the leading cause of death in children younger than 5 years old, and the frequency is increasing in countries with reliable data
  • 292
  • 06 Feb 2023
Topic Review
High-Cost Oncological Drugs
In Italy, drug expenditure governance is achieved by setting caps based on the percentage increase in hospital spending compared to the previous year. This method is ineffective in identifying issues and opportunities as it does not consider an analysis of the number of treated cases and per capita consumption in local and regional settings. The IRCCS (Scientific hospitalization and treatment institute) Istituto Romagnolo per lo Studio dei Tumori (IRST) “Dino Amadori” in Meldola, has developed and adopted an effective management model designed to oversee pharmaceutical expenditure, guarantee prescription appropriateness and quality of care to patients. The budget setting follows a structured process which evaluates determining factors of the expenditure such as expected patients calculated according to the epidemiology and to national and regional indications of appropriateness, mean cost per patient calculated on the average period of demonstrated efficacy of the drug and use of drugs with the best cost-effectiveness ratio. Strict monitoring and integrated purchasing processes allow for immediate corrective actions on expenditures, as well as a continuous dialogue with the region in order to guarantee consistent funding of IRST activities.
  • 292
  • 12 Jan 2022
Topic Review
Epidemiological Scenario of and Gastric Cancer in Chile
Helicobacter pylori (H. pylori) is a Gram-negative, microaerophilic bacterium that colonizes the gastric mucosa of more than 50% of the world’s population. In 1994, the International Agency for Research on Cancer classified it as a Group I carcinogen. Infection can be acquired in childhood and persist asymptomatically throughout life. H. pylori causes chronic gastritis. This can lead to peptic ulcers as well as premalignant lesions such as atrophic gastritis, intestinal metaplasia, and dysplasia, which can eventually trigger gastric cancer. Atrophic gastritis is the first step in the premalignant cascade and is characterized by the loss of gastric glandular cells, resulting in reduced acid production and an increase in pH levels. Intestinal metaplasia refers to the transformation of the gastric epithelium into an intestinal-type epithelium, which can be complete or incomplete, depending on the presence of goblet cells among the epithelial cells. 
  • 292
  • 07 Feb 2024
Topic Review
Novel Therapeutic Devices in Heart Failure
Heart failure (HF) constitutes a significant clinical problem and is associated with a sizeable burden for the healthcare system. Numerous novel techniques, including device interventions, are investigated to improve clinical outcome. Interventions regarding autonomic nervous system imbalance, i.e., baroreflex activation therapy; vagus, splanchnic and cardiopulmonary nerves modulation; respiratory disturbances, i.e., phrenic nerve stimulation and synchronized diaphragmatic therapy; decongestion management, i.e., the Reprieve system, transcatheter renal venous decongestion system, Doraya, preCardia, WhiteSwell and Aquapass, are presented.
  • 292
  • 24 Feb 2023
Topic Review
Training for Food Handlers in Italian Regions
Food safety has always been a public health challenge. Globally, food safety control is supported by laws and preventive measures, such as inspections conducted from primary production to market, “from farm to fork” as emphasized by the European Union and training of Food Handlers (FHs). This latter preventive measure plays a very important role, and for this reason a review of training courses regulations provided in the different Italian regions was conducted. 
  • 291
  • 14 Feb 2023
Topic Review
Psychometric Properties of Suboptimal Health Status Instruments
Suboptimal health status (SHS) measurement has now been recognized as an essential construct in predictive, preventive, and personalized medicine. Currently, there are limited tools, and an ongoing debate about appropriate tools.
  • 291
  • 27 Feb 2023
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