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Topic Review
Reducing the Children’s Intake of Ultra-Processed Foods
Excessive fat and fatty acids intake are associated with significant health hazards such as obesity or chronic diseases. The implementation of a relevant strategy for fat reduction, especially from ultra-processed foods, considered as low nutrient energy-dense products, is needed to promote health among children and prevent diet-related chronic diseases.
  • 479
  • 29 Jan 2022
Topic Review
Micro-Mobility User Pattern and Station Location in Thessaloniki
In recent years, European countries have been trying to cultivate electrical scooters (e-scooters) as an alternative form of micro-mobility. The purchase and maintenance costs of private e-scooters are expensive so cities have been collaborating with companies to construct an e-scooter rental network. There are two main features: the initial–final position of the e-scooter (the total distance is unknown) and the travel time. Most e-scooter rides refer to leisure trips but there is a portion of users that ride e-scooters for casual trips or commutes to and from work. Here, an electrical scooter network that covers the demand of the city of Thessaloniki is suggested. The implementation plan indicates three stages of construction up to the completion of the network.
  • 479
  • 27 Jun 2022
Topic Review
Athletes during an Ramadan Fasting Period
The Ramadan fasting period (RFP) means abstaining from consuming food and/or beverages during certain hours of the day—from sunrise to sunset. Engaging in exercise and sports during the RFP leads to the lipolysis of adipose tissue and an increase in the breakdown of peripheral fat, leading to an increase in fat consumption. The effects of the RFP on functional, hematological, and metabolic parameters needs further study as existing studies have reported contradictory results. The differences in the results of various studies are due to the geographical characteristics of Muslim athletes, their specific diets, and their genetics, which explain these variations.
  • 478
  • 30 Aug 2022
Topic Review
Cryptococcus neoformans
Cryptococcus neoformans var. neoformans is the second most prevalent agent of cryptococcosis in central Europe. Infections mostly present with localized skin and disseminated infections. Clinical isolates of C. neoformans var. neoformans present a substantial phenotypic variability. Median survival of G. mellonella varied between 6 and 14 days. C. neoformans var. neoformans isolates from disseminated infections showed stronger melanization and larger capsules.
  • 478
  • 25 Feb 2022
Topic Review
Biological Activities of Genus Scutellaria
Scutellaria (Lamiaceae) comprises over 360 species. Based on its morphological structure of calyx, also known as Skullcap, it is herbaceous by habit and cosmopolitan by habitat. The species of Scutellaria are widely used in local communities as a natural remedy. The genus contributed over three hundred bioactive compounds mainly represented by flavonoids and phenols, chemical ingredients which serve as potential candidates for the therapy of various biological activities.
  • 478
  • 21 Jul 2022
Topic Review
Smart Sensing Chair for Sitting Posture Monitoring
Smart sensing chairs, equipped with advanced sensor technologies such as Force Sensing Resistors (FSRs), show significant potential in mitigating the negative health impacts of incorrect sitting postures, which can lead to spinal misalignment and musculoskeletal disorders. Research emphasizes the use of sophisticated machine learning techniques, including Convolutional Neural Networks (CNNs) and Artificial Neural Networks (ANNs), for classifying sitting postures. Notably, these advanced models do not always outperform traditional models due to the limitations of the training datasets, which often lack sufficient diversity in representing different human body types and health conditions. This finding underscores the critical need for datasets that more accurately reflect the demographic and physiological diversity of users. Additionally, this research highlights a significant opportunity for innovation in user feedback mechanisms within smart sensing chairs, suggesting that enhanced interactive features could improve posture correction efforts and overall user health outcomes.
  • 483
  • 13 May 2024
Topic Review
AI Application in Rare Diseases
Emerging machine learning (ML) technologies have the potential to significantly improve the research and treatment of rare diseases, which constitute a vast set of diseases that affect a small proportion of the total population. Artificial Intelligence (AI) algorithms can help to quickly identify patterns and associations that would be difficult or impossible for human analysts to detect. Predictive modeling techniques, such as deep learning, have been used to forecast the progression of rare diseases, enabling the development of more targeted treatments. Moreover, AI has also shown promise in the field of drug development for rare diseases with the identification of subpopulations of patients who may be most likely to respond to a particular drug.
  • 478
  • 29 Mar 2023
Topic Review
High-Intensity Functional Training in Elderly with Cognitive Impairment
High Intensity Functional Training (HIFT) is a new exercise modality that emphasizes multi-joint functional movements adaptable to any fitness level and promotes greater muscle recruitment.
  • 478
  • 16 May 2022
Topic Review
Homocysteine Solution-Induced Response in OECTs Devices
Homocysteine (Hcy) is a non-protein, sulfur-containing amino acid, which is recognized as a possible risk factor for coronary artery and other pathologies when its levels in the blood exceed the normal range of between 5 and 12 μmol/L (hyperhomocysteinemia). At present, standard procedures in laboratory medicine, such as high-performance liquid chromatography (HPLC), are commonly employed for the quantitation of total Hcy (tHcy), i.e., the sum of the protein-bound (oxidized) and free (homocystine plus reduced Hcy) forms, in biological fluids (particularly, serum or plasma). Here, the response of Aerosol Jet-printed organic electrochemical transistors (OECTs), in the presence of either reduced (free) and oxidized Hcy-based solutions, was analyzed. Two different experimental protocols were followed to this end: the former consisting of gold (Au) electrodes’ biothiol-induced thiolation, while the latter simply used bare platinum (Pt) electrodes. Electrochemical impedance spectroscopy (EIS) analysis was performed both to validate the gold thiolation protocol and to gain insights into the reduced Hcy sensing mechanism by the Au-gated OECTs, which provided a final limit of detection (LoD) of 80 nM. For the OECT response based on Platinum gate electrodes, on the other hand, a LoD of 180 nM was found in the presence of albumin-bound Hcy, with this being the most abundant oxidized Hcy-form (i.e., the protein-bound form) in physiological fluids. Despite the lack of any biochemical functionalization supporting the response selectivity, the findings discussed in this work highlight the potential role of OECT in the development of low-cost point-of-care (POC) electronic platforms that are suitable for the evaluation, in humans, of Hcy levels within the physiological range and in cases of hyperhomocysteinemia.
  • 478
  • 16 Nov 2021
Topic Review
Hotspots and Frontiers of Urban Floods
Current research shows that the number of papers published in the field of urban flooding is generally increasing year by year, and the research focus has shifted from exploring hydrological processes to adopting advanced management measures to solve urban flooding problems. 
  • 477
  • 15 Dec 2021
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