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Topic Review
Brucella melitensis Vaccines
Brucella melitensis is recognized as one of the predominant zoonotic pathogens globally. Live-attenuated vaccine Rev 1 is currently the most effective vaccine for controlling B. melitensis in small ruminants. While Brucella inactivated, nanoparticle, and subunit vaccines are less effective and require multiple doses, live-attenuated vaccines are less expensive and more efficacious. Several drawbacks are associated with the administration of current attenuated B. melitensis vaccines, including interference with serological diagnostic tests, inducing abortion in pregnant animals, shedding in milk, and zoonotic infections in humans. 
  • 296
  • 06 Dec 2023
Topic Review
Visually Impaired Persons’ Assistance
The development of new solutions to assist blind people is a major research domain having great potential to enhance the daily lives of such people. These innovative solutions aim to augment the perception of the surrounding environment for the blind and severely visually impaired. 
  • 180
  • 06 Dec 2023
Topic Review
Importance of Micronutrients in the Older Adults
Aging precipitates significant changes in physical, cognitive, and physiological realms, profoundly impacting nutritional needs. Aging brings declines in muscle mass, immune function, bone density, nutrient absorption, metabolism, and oral health status. Micronutrients (e.g., omega-3 fatty acids, vitamins, and minerals—selenium, fluoride, zinc, iron, and manganese), are of particular importance and are fundamental in terms of human metabolism, physiology, and general and oral health.
  • 167
  • 04 Dec 2023
Topic Review
Microfluidic-Based Smart Diagnostic Platform for COVID-19 Diagnosis
The pandemic of COVID-19 and its widespread transmission have made people realize the importance of early, quick diagnostic tests for facilitating effective cure and management. The primary obstacles encountered were accurately distinguishing COVID-19 from other illnesses including the flu, common cold, etc. While the polymerase chain reaction technique is a robust technique for the determination of SARS-CoV-2 in patients of COVID-19, there arises a high demand for affordable, quick, user-friendly, and precise point-of-care (POC) diagnostic in therapeutic settings. The necessity for available tests with rapid outcomes spurred the advancement of POC tests that are characterized by speed, automation, and high precision and accuracy. Paper-based POC devices have gained increasing interest in recent years because of rapid, low-cost detection without requiring external instruments. 
  • 153
  • 04 Dec 2023
Topic Review
Active Aging and Smart Public Parks
The global population is aging, with the percentage of people over 60 expected to rise from 12% to 22% and 33% residing in developed countries. However, most cities lack the appropriate infrastructure to support aging citizens in active aging and traversing the urban landscape, negatively impacting their quality of life. Studies have shown that public parks and green spaces can contribute to a higher quality of life and wellbeing. Also, smart cities are intended to improve the wellbeing and health of their inhabitants. However, most solutions are typically implemented indoors and tend to overlook the needs of older adults. A smart city should consider the increasing rate of aging and give more importance to outdoor environments as a key aspect of quality of life. 
  • 435
  • 04 Dec 2023
Topic Review
Post-Traumatic Stress Disorder in Adolescents
Trauma in childhood and adolescence has long-term negative consequences in brain development and behavior and increases the risk for psychiatric disorders. Among them, post-traumatic stress disorder (PTSD) during adolescence illustrates the connection between trauma and substance misuse, as adolescents may utilize substances to cope with PTSD.
  • 210
  • 04 Dec 2023
Topic Review
World-Renowned “Swiss” Pediatricians
The early and correct recognition of rare pediatric diseases is essential for decisions related to treatment options, the monitoring of treatment results, and the prevention of complications, as well as the estimation of prognosis and the counselling of patients, parents, and caregivers, including a risk estimation for recurrence in future pregnancies.
  • 239
  • 04 Dec 2023
Topic Review
Types of Short Text on Social Media
The rapid expansion of social media platforms has resulted in an unprecedented surge of short text content being generated on a daily basis. The different types of short text on social media is essential for developing effective summarization techniques that cater to the unique characteristics of each platform and user interaction.
  • 523
  • 01 Dec 2023
Topic Review
Biomarkers in Monitoring Radiotherapy Toxicity
Radiotherapy (RT) is a major part of cancer treatment. The reported variability in patient response to this modality can interfere with the continuation of best-possible care, promote side effects, and lead to long-term morbidity. Tools to predict a patient’s response to radiation could be highly useful in improving therapeutic outcomes while minimizing unnecessary and toxic exposure to radiation.
  • 266
  • 30 Nov 2023
Topic Review
Potential Mechanisms of Action of Diacutaneous Fibrolysis
Diacutaneous Fibrolysis (DF) is an instrumentally assisted manual therapy technique defined as “a specific instrumental intervention for normalizing the musculoskeletal system function after a precise diagnosis and preserving the skin’s integrity”. The aim of this technique is soft tissue mobilization with the assistance of specially designed, hook-shaped steel instruments in different musculoskeletal structures, such as the myofascia, aponeurosis, tendons, ligaments and scar tissues. 
  • 182
  • 30 Nov 2023
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