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Topic Review
Family-Centred Care for Children with Biopsychosocial Support Needs
Family-centred care is associated with improved health and well-being of the child, improved parental reports of satisfaction of care, greater efficiency of health care resources, increased access to care, better family-provider communication and better transition services. Descriptions and principles of family-centred care are well established but there are very few specific definitions and a systematic review by Kuhlthau et al. noted the need to more clearly define and operationalise family-centred care.
  • 343
  • 23 Dec 2021
Topic Review
Escherichia coli Isolated from Migratory Birds
Antibiotic resistance is a global health crisis. Migratory birds are carriers of various types of pathogens including multidrug  Escherichia coli. However, their roles in the dissemination of these resistant pathogens are still being neglected in Bangladesh. MDR E. coli carried by many of these migratory birds could also be positive for APEC-associated virulence genes, which can seriously contribute to the development of human and animal diseases. 
  • 565
  • 23 Dec 2021
Topic Review
Depression/Anxiety Factors in Old during COVID-19 Pandemic
COVID-19 represents a threat to public health and the mental health of the aged population. Female gender, loneliness, poor sleep quality and poor motor function were identified as factors associated with both depression and anxiety. Levels of physical activity or exercise were associated with depression, with lower levels of activity identified as risk factors and exercising regularly as a protective factor. Several physical health conditions may be associated with anxiety. Aspects related to having a stable and high monthly income represent protective factors for both depression and anxiety.
  • 344
  • 23 Dec 2021
Topic Review
Outpatient Antibiotic Use in Canadian Provinces
Antimicrobials are among the most prescribed medications in Canada, with over 90% of antibiotics prescribed in outpatient settings. Seniors prescribed antimicrobials are particularly vulnerable to adverse drug events and antimicrobial resistance. The extent of inappropriate antibiotic prescribing in outpatient Canadian medical practice, and the potential long-term trends in this practice, are unknown.
  • 392
  • 23 Dec 2021
Topic Review
YB1 in Triple Negative Breast Cancer
The Y Box binding protein 1 (YB1) is a multifunctional protein, found both in the cytoplasm and inside the nucleus, that belongs to the highly conserved Cold Shock Domain protein family. YB1 is highly expressed in TNBC tumors of AA origin when compared to CAs. Increased expression levels and activity of YB1 correlates with poor disease outcomes, resistance to chemotherapy, and the activation of the cancer stem cell (CSC) phenotype, with higher levels in AA than in CA TNBC tumors.
  • 774
  • 23 Dec 2021
Topic Review
Innate Immunity Promotes Programmed Death of Individual Organisms
Over-activation of innate immunity in response to bacterial or viral (including COVID-19) infections, massive trauma, or ischemia/reperfusion often causes severe illness and death. We suggest that such severe outcomes may be manifestations of an altruistic suicidal strategy protecting the entire population from the spread of pathogens and from dangerous pathologies rather than aberrant hyperstimulation of defense responses. 
  • 513
  • 22 Dec 2021
Topic Review
The Current Green Economy Situations in European Union
Energy is undoubtedly one of the fundamental factors in the development of economies around the world. This is particularly evident during crises related to the reduction of supplies or the lack of energy sources. For example, the oil crisis of the 1970s of the twentieth century showed the problem of energy security, which has returned today and is one of the important topics of discussion in the European Union (EU) countries. Changes in the situation of the energy markets and geopolitical conditions show that the problem of energy security is fundamental for the functioning of modern economies. It directly influences economic development and other strategic areas, including the Lisbon Strategy for Growth and Jobs and the Millennium Development Goals.
  • 464
  • 22 Dec 2021
Topic Review
The Early Days of Personal Solar Ultraviolet Dosimetry
In the early 1970s, environmental conservationists were becoming concerned that a reduction in the thickness of the atmospheric ozone layer would lead to increased levels of ultraviolet (UV) radiation at ground level, resulting in higher population exposure to UV and subsequent harm, especially a rise in skin cancer. At the time, no measurements had been reported on the normal levels of solar UV radiation which populations received in their usual environment, so this lack of data, coupled with increasing concerns about the impact to human health, led to the development of simple devices that monitored personal UV exposure. 
  • 405
  • 22 Dec 2021
Topic Review
Physical Activity, Sedentary Behavior and Wrist Accelerometer
The switch from hip-placed to wrist-worn accelerometers has signaled the focus on developing novel approaches to process raw acceleration data without overly relying on traditional cut points. Indeed, wrist-worn raw acceleration data have been increasingly utilized to capture individuals’ physical behavior patterns. Several traditional methods and cut points have been developed to deal with raw wrist acceleration data, yet they appear to either overestimate or underestimate the outcomes.
  • 1.1K
  • 22 Dec 2021
Topic Review
Lonomia obliqua Envenoming
The hemorrhagic syndrome is one of the most serious complications in patients who have  been in contact with the Lonomia caterpillar bristles. Although 26 species of the genus Lonomia (Saturniidae family) are distributed in the American continent, the most studied species are L. obliqua and L. achelous caterpillars; both are capable of inducing hemorrhagic effects in humans. Envenoming by L. obliqua caterpillars was considered a public health problem in southern Brazil. The hemostatic disturbances observed in the envenoming by L. obliqua caterpillars, result in a consumption coagulopathy, resembling a disseminated intravascular coagulation (DIC) and secondary fibrinolysis, which can lead to the hemorrhagic syndrome. The main complication of L. obliqua envenomation is acute renal failure, which can occur in up to 12% of the cases, being frequent in patients over 45 years old and in those with heavy bleeding. Besides that, some deaths related to hemorrhage and renal failure have been reported. However, the early diagnosis and proper treatment with  antilonomic serum (ALS), produced by the Butantan Institute (SP/Brazil), within 12 h of contact can prevent severe coagulopathy and hemorrhage events. 
  • 428
  • 22 Dec 2021
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