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Topic Review
Anti-CCR5 Therapy, Breast Cancer and Its Microenvironment
Breast cancer represents the most common malignancy among women in the world. The local microenvironment around the tumor plays a great role in cancer progression and invasion, representing a promising therapeutic target. CCL5 is a potent chemokine with a physiological role of immune cell attraction and has gained particular attention in R&D for breast cancer treatment. Its receptor, CCR5, is a well-known co-factor for HIV entry through the cell membrane and CCR5 blocking represents a mainstay of HIV treatment. Interestingly, CCL5 is currently described as key pro-oncogenic factor, especially in breast cancer. Several studies blocking the CCL5/CCR5 axis show cancer cells become less invasive and less malignant, with less oncogenic extracellular matrices.
  • 448
  • 28 Nov 2022
Topic Review
Antibiotic Residues in Food
The usage of antibiotics has been, and remains, a topic of utmost importance; on the one hand, for animal breeders, and on the other hand, for food safety. Although many countries have established strict rules for using antibiotics in animal husbandry for the food industry, their misuse and irregularities in compliance with withdrawal periods are still identified. In addition to animal-origin foods that may cause antibiotic residue problems, more and more non-animal-origin foods with this type of non-compliance are identified. 
  • 633
  • 31 May 2022
Topic Review
Antibiotics in Animal Origin Food
Antibiotics are antimicrobial substances formed by or obtained from microorganisms that kill or inhibit the growth of other microorganisms. Antibiotics were first approved for use in livestock by the US Food and Drug Administration (FDA) in 1951. The European Union has forbidden the use of antibiotics as growth promoters since 2006. Its abusive use leads to the presence of antibiotic residues (AR) in foods of animal origin which is associated with antibiotic resistance.
  • 327
  • 01 Mar 2023
Topic Review
Antioxidants for Patients with Fibromyalgia
Fibromyalgia (FM) is a syndrome characterized by chronic widespread pain. Pain is the predominant symptom; allodynia and hyperalgesia are also frequent. These patients also present severe fatigue, impaired cognition, and sleep disturbance, among others. In recent years, antioxidant supplements have become popular to counteract the effects of oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. 
  • 1.7K
  • 12 May 2022
Topic Review
Antioxidants in Hops
Hop plant (Humulus lupulus L.) has been used by humans for ages, presumably first as a herbal remedy, then in the manufacturing of different products, from which beer is the most largely consumed. Female hops cones have different useful chemical compounds, an important class being antioxidants, mainly polyphenols.
  • 528
  • 10 Feb 2022
Topic Review
Antitumor Potential of Annona muricata Linn
Annona muricata (Am) is a plant used in traditional Mexican medicine to treat cancer. It is widely distributed in tropical and subtropical regions. A. muricata  is known as “graviola”, “soursop”, and “guanabana” in Mexico is called “zapote de Viejas,” “catucho,” and “cabeza de negro.” 
  • 531
  • 18 Jan 2022
Topic Review
Antiviral Potential of Plants against COVID-19 during Outbreaks
COVID-19 has become a pandemic in most parts of the world. Although vaccines are available to fight the infection, their safety and clinical trial data are still questionable. Social distancing, isolation, the use of sanitizer, and personal productive strategies have been implemented to prevent the spread of the virus. Moreover, the search for a potential therapeutic molecule is ongoing. Based on experiences with outbreaks of SARS and MERS, many research studies reveal the potential of medicinal herbs/plants or chemical compounds extracted from them to counteract the effects of these viral diseases.
  • 495
  • 17 Nov 2022
Topic Review
Anxiety Linked to COVID-19
The COVID-19 pandemic has incited a rise in anxiety, with uncertainty regarding the specific impacts and risk factors across multiple populations. A qualitative systematic research was conducted to investigate the prevalence and associations of anxiety in different sample populations in relation to the COVID-19 pandemic. 
  • 409
  • 11 Mar 2022
Topic Review
Application of IoT in Virus Detection
Today, healthcare system models should have high accuracy and sensitivity so that patients do not have a misdiagnosis. For this reason, sufficient knowledge of the area is required, with the medical staff being able to validate the correctness of their decisions. Therefore, artificial intelligence (AI) in combination with other emerging technologies could provide many benefits in the medical sector.
  • 92
  • 11 Mar 2024
Topic Review
Application of Standardized Regression Coefficient in Meta-Analysis
The β coefficient is the estimate resulting from an analysis carried out on variables that have been standardized so that their standard deviations (and variances) are equal to one. Therefore, the standardized coefficient refers to how many standard deviations the response or outcome variable will change per a standard deviation increase in the explanatory or predictor variable. Thus, the standardized coefficient β can be regarded as an attempt to make regression coefficients more comparable, and can be used as an effect-size estimate when the exposure levels in original studies are measured in different units of measurement.
  • 6.1K
  • 14 Sep 2022
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