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Topic Review
Antimicrobial Resistance Surveillance Strategy in Uganda
Uganda is making strides and progress with regard to developing and implementing a functional AMR surveillance strategy for human health. Although numerous challenges still exist, following the laboratory health system strengthening approach, the readily addressable issues are with the health infrastructure, its integration, capacity building and operation. Antibiotic resistance and its mechanisms have now been in existance for over decades, and its drivers in both clinical, human, agriculture-veterinary go beyond the community and clinical aspects. Its noteworthy that the emergency of resistance is a natural phenomenon in the environment but kin to climate change. If left unchecked, this has great potential of undoing all medical and agricultural advancements of the entire previous century. Implementation of country driven program based surveillance that embraces a One Health Approach is the ideal approach to understanding and solving this one  health challenge that seems to be wicked in solve at the face mankind.
  • 923
  • 30 Nov 2021
Topic Review
Seagrass Posidonia oceanica，Human Health
Posidonia oceanica (L.) Delile is a marine plant endemic to the Mediterranean, traditionally used in some medical applications. However, the potential benefits of P. oceanica for human health have only recently been documented. New knowledge gained on the bioactive properties of P. oceanica allow the scientific community to look at this marine plant as a promising source of natural therapeutic products for human health.Experimental investigations conducted in both in vitro cellular models and in vivo animal models pave the way for new research projects that aim to develop alternative and complementary therapeutic strategies based on P. oceanica against a wide range of pathological conditions.
  • 924
  • 07 Feb 2022
Topic Review
Dry Eye and Probiotics
Probiotics are defined as live microorganisms that present health benefits when administered in adequate amounts. Prebiotics refer to substrates that microorganisms use to bestow health benefits upon host. Evidence regarding their effects on the ocular surface, especially dry eye, are now just emerging. Both rodent and human studies regarding gut microbiota in Sjögren’s syndrome and environmental dry eye are explored, and we discussed the effects of prebiotics and probiotics on dry eye in this section. 
  • 923
  • 06 Jul 2021
Topic Review
Industrial Animal Farming and COVID-19
The threat of zoonoses (i.e., human infectious diseases transmitted from animals) because of industrial animal farming may be receiving less attention in society due to the putative wildlife origin of COVID-19. To identify societal responses to COVID-19 that do address or affect the risk of future zoonoses associated with industrial animal farming, the literature was screened for measures, actions, proposals and attitudes following the guidelines of a scoping review. Forty-one articles with relevant information published between 1 January 2020 and 30 April 2021 were identified directly or indirectly via bibliographies from 138 records retrieved via Google Scholar. Analysis of relevant content revealed ten fields of policy action amongst which biosecurity and change in dietary habits were the dominant topics. Further search for more relevant records within each field of policy action retrieved another 8 articles. Identified responses were furthermore classified and evaluated according to groups of societal actors, implying different modes of regulation and governance. Based on the results, a suggested policy strategy is presented for moving away from food production in factory farms and supporting sustainable farming, involving the introduction of a tax on the demand side and subsidies for the development and production of alternative meat.
  • 923
  • 31 Aug 2021
Topic Review
Endolysins
Endolysins are phage-encoded enzymes utilized by mature phage virions to hydrolyze the cell wall from within. There is significant evidence that proves the ability of endolysins to degrade the peptidoglycan externally without the assistance of phage. Thus, their incorporation in therapeutic strategies has opened new options for therapeutic application against bacterial infections in the human and veterinary sectors, as well as within the agricultural and biotechnology sectors. While endolysins show promising results within the laboratory, it is important to document their resistance, safety, and immunogenicity for in-vivo application.
  • 923
  • 24 Mar 2021
Topic Review
Soluble Dietary Fiber
Dietary fiber is a widely recognized nutrient for human health. Previous studies proved that dietary fiber has significant implications for gastrointestinal health by regulating the gut microbiota. Moreover, mechanistic research showed that the physiological functions of different dietary fibers depend to a great extent on their physicochemical characteristics, one of which is solubility.
  • 922
  • 15 Sep 2022
Topic Review
Ischemic Stroke
"The term stroke is defined as ”…a neurological deficit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause, including cerebral infarction, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH)…”, thus comprising an intraluminal obstructive/ischemic and/or wall tear and a lesion mechanism.
  • 922
  • 29 Oct 2020
Topic Review
TERF2
Telomeric repeat-binding factor 2 is a protein that is present at telomeres throughout the cell cycle. It is also known as TERF2, TRF2, and TRBF2, and is encoded in humans by the TERF2 gene. It is a component of the shelterin nucleoprotein complex and a second negative regulator of telomere length, playing a key role in the protective activity of telomeres. It was first reported in 1997 in the lab of Titia de Lange, where a DNA sequence similar, but not identical, to TERF1 was discovered, with respect to the Myb-domain. De Lange isolated the new Myb-containing protein sequence and called it TERF2.
  • 922
  • 03 Nov 2022
Topic Review
Gelidium in Circular Economy Framework
Gelidium corneum (Giant Gelidium or Atlantic agar) is a well-known red seaweed harvested for its high-quality agar content. Agar is a mixture of the polysaccharides used in the food industry as a gelling, thickener, clarifying, and stabilizer agent. The best agar quality is also used in the laboratory as bacteriological agar.
  • 922
  • 06 Jul 2022
Topic Review
Antioxidant
The primary objectives of modern agriculture includes the environmental sustainability, low production costs, improved plants’ resilience to various biotic and abiotic stresses, and high sowing seed value. Delayed and inconsistent field emergence poses a significant threat in the production of agri-crop, especially during drought and adverse weather conditions. To open new routes of nutrients’ acquisition and revolutionizing the adapted solutions, stewardship planswill be needed to address these questions.One approach is the identification of plant based bioactive molecules capable of altering plant metabolism pathways which may enhance plant performance in a brief period of time and in a cost-effective manner.A biostimulant is a plant material, microorganism, or any other organic compound that not only improves the nutritional aspects, vitality, general health but also enhances the seed qualityperformance.
  • 921
  • 07 May 2021
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