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Topic Review
Effects of Heat Stress on Livestock
Climate change is receiving more consideration worldwide, and the impact on animal production is particularly relevant due to increasing demand and limitations to production. When predicted temperature/humidity increases as a result of climate change are added, the proportion of time that they are exposed to heat stress becomes more severe. It was concluded that the effects of heat stress are becoming critical for livestock production systems, especially during summer. Livestock responds to these changes by using different mechanisms to survive, but production efficiency is severely compromised by heat stress. Injury and death may even ensue if mitigation measures are not taken quickly. 
  • 939
  • 05 Aug 2022
Topic Review
Tumor Cell Infiltration into the Brain in Glioblastoma
Glioblastoma is the most common and malignant primary brain tumor, defined by its highly aggressive nature. Despite the advances in diagnostic and surgical techniques, and the development of novel therapies in the last decade, the prognosis for glioblastoma is still extremely poor. One major factor for the failure of existing therapeutic approaches is the highly invasive nature of glioblastomas. The extreme infiltrating capacity of tumor cells into the brain parenchyma makes complete surgical removal difficult; glioblastomas almost inevitably recur in a more therapy-resistant state, sometimes at distant sites in the brain. Therefore, there are major efforts to understand the molecular mechanisms underpinning glioblastoma invasion; however, there is no approved therapy directed against the invasive phenotype as of now.
  • 939
  • 07 Feb 2022
Topic Review
Arabidopsis RETICULON-LIKE4 (RTNLB4)
Agrobacterium tumefaciens genetically transforms plant cells by transferring the transfer-DNA (T-DNA) and virulence (Vir) proteins from bacteria via a VirB-encoded type IV secretion system into plants. The effectors manipulate plant proteins to assist in T-DNA transfer, integration, and expression in plant cells. The Arabidopsis reticulon-like (RTNLB) proteins are located in the endoplasmic reticulum and are involved in endomembrane trafficking in plant cells. We functionally characterized reticulon-like protein B4 (RTNLB4), which interacted with the A. tumefaciens VirB2 protein, a major component of A. tumefaciens T-pilus. Overexpression or knockdown of RTNLB4 affected the expression of A. tumefaciens elf18 peptide-induced plant defense-related genes and could affect Agrobacterium-mediated transformation rates. Pre-treatment with elf18 peptide decreased Agrobacterium-mediated transient expression efficiency more in wild-type seedlings than RTNLB4 O/E transgenic plants, which suggests that the induced defense responses in RTNLB4 O/E transgenic plants might be affected after bacterial elicitor treatments. We also showed that two VirB2 peptides induced the expression of defense-related genes and H2O2 production and inhibited seedling growth. These typical pathogen-associated molecular pattern-trigged immune responses were less induced in RTNLB4 overexpression transgenic plants. Our findings provide strong evidence that RTNLB4 has major roles in the A. tumefaciens elf18 and VirB2 peptide-derived plant defense responses. We believe this study advances our understanding of possible functions of the RTNLB4 protein in the A. tumefaciens infection process and plant immunity.
  • 939
  • 01 Nov 2020
Biography
Amory Lovins
Amory Bloch Lovins (born November 13, 1947)[1] is an American physicist, environmental scientist, writer, and Chairman/Chief Scientist of the Rocky Mountain Institute. He has worked in the field of energy policy and related areas for four decades. He was named by Time (magazine) magazine one of the World's 100 most influential people in 2009. Lovins worked professionally as an environmentalist
  • 939
  • 24 Nov 2022
Topic Review
Management of Pike in Alaska
Northern pike are an invasive species in southcentral Alaska and have caused the decline and extirpation of salmonids and other native fish populations across the region. Northern pike control actions are tailored to the unique conditions of waters prioritized for their management, and all efforts support the goal of preventing further spread of this invasive aquatic apex predator to vulnerable waters.
  • 938
  • 26 Aug 2021
Topic Review
Salt Stress in Plants
Salinization of soils and freshwater resources by natural processes and/or human activities has become an increasing issue that affects environmental services and socioeconomic relations. In addition, salinization jeopardizes agroecosystems, inducing salt stress in most cultivated plants (nutrient deficiency, pH and oxidative stress, biomass reduction), and directly affects the quality and quantity of food production. Depending on the type of salt/stress (alkaline or pH-neutral), specific approaches and solutions should be applied to ameliorate the situation on-site.
  • 938
  • 23 Mar 2022
Topic Review
Drought Stress in Grain Legumes
Grain legumes are important sources of proteins, essential micronutrients and vitamins and for human nutrition. Climate change, including drought, is a severe threat to grain legume production throughout the world. The yield loss of grain legumes varies from species to species, even variety to variety within a species, depending upon the severity of drought stress and several other factors, such as phenology, soil textures and agro-climatic conditions. Closure of stomata leads to an increase in leaf temperature by reducing the transpiration rate, and, so, the legume plant faces another stress under drought stress. The biosynthesis of reactive oxygen species (ROS) is the most detrimental effect of drought stress. Legumes can adapt to the drought stress by changing their morphology, physiology and molecular mechanism. Improved root system architecture (RSA), reduced number and size of leaves, stress-induced phytohormone, stomatal closure, antioxidant defense system, solute accumulation (e.g., proline) and altered gene expression play a crucial role in drought tolerance. 
  • 938
  • 30 Nov 2021
Topic Review
Zebrafish Models of Neuroblastoma
For nearly a decade, researchers in the field of pediatric oncology have been using zebrafish as a model for understanding the contributions of genetic alternations to the pathogenesis of neuroblastoma (NB), and exploring the molecular and cellular mechanisms that underlie neuroblastoma initiation and metastasis.
  • 937
  • 18 Mar 2021
Topic Review
VDAC1
The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for cellular fate.
  • 938
  • 26 Nov 2020
Topic Review
GPR in Wood Structures
Ground penetrating radar (GPR) is a nondestructive inspection tool based upon the electromagnetic (EM) theory that radio wave propagation is governed by the EM properties of a dielectric material. GPR has many characteristics that make it attractive as an inspection tool for wood: it is faster than many acoustic and stress wave techniques; it does not require the use of a couplant; while it can also detect the presence of moisture. Moisture detection is of prime concern, and several researchers have labored to measure internal moisture using GPR.
  • 938
  • 27 May 2021
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