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Topic Review
Detecting Analytes in Urine for Urinalysis
Human urine samples contain several components that can indicate the health condition of a patient, and therefore aid in the diagnosis of common clinical conditions such as diabetes mellitus (DM), urinary tract infections (UTIs), renal stone disease, kidney disorders, liver problems, obesity, other metabolic disorders, or fetal hypothyroidism. Urine samples also provide evidence of underlying health problems in pre-symptomatic and asymptomatic individuals, which can facilitate early intervention and therapy. These benefits play an important role in encouraging individual access to continuous and regular health monitoring.
  • 1.4K
  • 06 Dec 2022
Topic Review
Phytohormone Regulation of Apple-Fruit Ripening
Apple (Malus domestica) is, globally, one of the largest fruits in terms of cultivated area and yield. Apple fruit is generally marketed after storage, which is of great significance for regulating the market supply in the off-season of fruit production. Apple-fruit ripening, which culminates in desirable changes in structural and textural properties, is governed by a complex regulatory network. 
  • 1.4K
  • 22 Oct 2021
Biography
Mustafa Tlass
Mustafa Abdul Qadir Tlass (Arabic: مصطفى طلاس; 11 May 1932 – 27 June 2017) was a Syrian senior military officer and politician who was Syria's minister of defense from 1972 to 2004.[1] He was part of the four-member Regional Command during the Hafez Assad era. Tlass was born in Rastan near the city of Homs to a prominent local Sunni Muslim family on 11 May 1932.[2] His father, Abdu
  • 1.4K
  • 05 Dec 2022
Topic Review
ADP-Ribosyltransferase Toxin
ADP-ribosyltransferases (ARTs) are a well-known type of bacterial toxin. They transfer an ADP-ribose moiety from nicotinamide adenine dinucleotide (NAD+) onto a target protein to generate an ADP-ribosylated protein and nicotinamide. The bulky and negatively charged ADP-ribose moiety affects the protein function by sterically blocking interactions with partner molecules, inducing conformational changes, or creating docking sites for new interaction partners.
  • 1.4K
  • 25 Jan 2021
Biography
Karl Schwarzschild
Karl Schwarzschild (9 October 1873 – 11 May 1916) was a Germany physicist and astronomer. He was also the father of astrophysicist Martin Schwarzschild. Schwarzschild provided the first exact solution to the Einstein field equations of general relativity, for the limited case of a single spherical non-rotating mass, which he accomplished in 1915, the same year that Einstein first introduced g
  • 1.4K
  • 01 Dec 2022
Topic Review
Protein Folding: Enigma and Solution
Protein folding is a process that converts the unfolded, disordered protein chain into a chain having a definite, unique three-dimensional structure.
  • 1.4K
  • 23 Apr 2021
Topic Review
Ecology and Evolution of Saccharomyces cerevisiae
The yeast distributes ubiquitously in nature with clearly structured populations. The baker’s yeast Saccharomyces cerevisiae has become a powerful model in ecology and evolutionary biology. The global genetic diversity of S. cerevisiae is mainly contributed by strains from Far East Asia, and the ancient basal lineages of the species have been found only in China, supporting an ‘out-of-China’ origin hypothesis. The wild and domesticated populations are clearly separated in phylogeny and exhibit hallmark differences in sexuality, heterozygosity, gene copy number variation (CNV), horizontal gene transfer (HGT) and introgression events, and maltose utilization ability. The domesticated strains from different niches generally form distinct lineages and harbor lineage-specific CNVs, HGTs and introgressions, which contribute to their adaptations to specific fermentation environments. 
  • 1.4K
  • 01 Mar 2022
Topic Review
Cyanobacterial Extracellular Polymeric Substances
Biopolymers derived from polysaccharides are a sustainable and environmentally friendly alternative to the synthetic counterparts available in the market. Due to their distinctive properties, the cyanobacterial extracellular polymeric substances (EPS), mainly composed of heteropolysaccharides, are a valid alternative to address several biotechnological and biomedical challenges. However, for the successful exploitation of cyanobacterial EPS, it is important to obtain polymers with high purity levels and exploit different strategies of  functionalization  to obtain EPS tailored for given applications. Considering all this, available approaches to isolate, purify and chemically modify cyanobacterial EPS are discussed.  
  • 1.4K
  • 30 Jul 2020
Topic Review
Dermal Fibroblasts
Scarring and regeneration are two physiologically opposite endpoints to skin injuries, with mammals, including humans, typically healing wounds with fibrotic scars. We aim to provide an updated review on fibroblast heterogeneity as determinants of the scarring–regeneration continuum. We discuss fibroblast-centric mechanisms that dictate scarring–regeneration continua with a focus on intercellular and cell–matrix adhesion. Improved understanding of fibroblast lineage-specific mechanisms and how they determine scar severity will ultimately allow for the development of antiscarring therapies and the promotion of tissue regeneration.
  • 1.4K
  • 30 Oct 2020
Topic Review
Biological Control of Bulb Mites
Mites of the genus Rhizoglyphus (Acari: Acaridae) are serious pests of plants belonging to the orders Liliales and Asparagales such as onions, garlic, lilies, and tulips. Their control by synthetic pesticides is becoming problematic as a result of resistance development in these mites and environmental and health issues. New pest control methods thus need to be developed. Efforts to develop biological control programs for bulb mites have taken place in a number of countries. Several biocontrol agents have been tested against Rhizoglyphus spp. under laboratory and some also under field conditions. The most promising results have been obtained with acaropathogenic/entomopathogenic fungi and predatory mites as described below. Other possible prospective control agents attacking mites are viruses, bacteria, and protista, but except for some bacteria their efficacy against bulb mites has not been investigated yet.
  • 1.4K
  • 29 Jul 2022
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