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Topic Review
Application of Microalgae in Cosmetics
Microalgae produce a number of secondary metabolites with anti-inflammatory, anti-blemish and antimicrobial activities. Certain microalgal extracts such as Arthrospira platensis, Chlorella vulgaris, and Dunaliella salina can be used for repairing skin aging, healing and preventing wrinkle formation. The microalgae or its components’ activity is the basis for the creation of several commercially available cosmetics and cosmeceuticals.
  • 2.2K
  • 23 Apr 2023
Topic Review
Ice Crystal
Most of the aquatic products are caught from distant seas which make them prone to deterioration and quality losses. One of the main strategies that can be used to increase shelf life and maintain product quality is freezing. During freezing, however, the ice crystals formed may considerably impact the cellular integrity, resulting in loss and degradation of food quality.
  • 2.2K
  • 07 Feb 2021
Topic Review
Marsupial Lion
The marsupial lion (Thylacoleo carnifex) is an extinct species of carnivorous marsupial mammal that lived in Australia from the early to the late Pleistocene (1,600,000–46,000 years ago). Despite its name, it is not closely related to the lion, but is a member of the order Diprotodontia, one of the taxonomic groups of Australian marsupials.
  • 2.2K
  • 20 Oct 2022
Topic Review
GPCRs Regulate DNA Integrity
G protein-coupled receptors (GPCRs) and their associated signaling proteins represent one of the most diverse cellular signaling systems involved in both physiological and pathophysiological processes. Aging represents perhaps the most complex biological process in humans and involves a progressive degradation of systemic integrity and physiological resilience. This is in part mediated by age-related aberrations in energy metabolism, mitochondrial function, protein folding and sorting, inflammatory activity, signal transduction fidelity and genomic stability. An increased rate of unrepaired DNA damage is considered to be one of the key ‘hallmarks’ of aging. Over the last two decades our appreciation of the complexity of GPCR signaling systems has expanded their functional signaling repertoire. One such example of this is the incipient role of GPCRs and GPCR-interacting proteins in DNA damage and repair (DDR) mechanisms. Emerging data now suggest that GPCRs could function as stress sensors for intracellular damage such as oxidative stress. Given this role of GPCRs in the DNA damage response process, coupled to the effective history of drug targeting of these receptors, this suggests that one important future activity of GPCR therapeutics is the rational control of DNA damage repair systems.
  • 2.1K
  • 30 Apr 2021
Topic Review
Food Informatics
Food Informatics is the collection, preparation, analysis, and smart use of data from agriculture, the food supply chain, food processing, retail, and smart (consumer) health for knowledge extraction to conduct an intelligent analysis and reveal optimizations to be applied to food production, food consumption, for food security, and the end of life of food products.
  • 2.1K
  • 10 Dec 2021
Topic Review
Streptococcus gordonii
Streptococcus gordonii, a Gram-positive bacterium, is a commensal bacterium that is commonly found in the skin, oral cavity, and intestine.  It is also known as an opportunistic pathogen that can cause local or systemic diseases, such as apical periodontitis and infective endocarditis. S. gordonii, an early colonizer, easily attaches to host tissues, including tooth surfaces and heart valves, forming biofilms. S. gordonii penetrates into root canals and blood streams, subsequently interacting with various host immune and non-immune cells. The cell wall components of S. gordonii, which include lipoteichoic acids, lipoproteins, serine-rich repeat adhesins, peptidoglycans, and cell wall proteins, are recognizable by individual host receptors. They are involved in virulence and immunoregulatory processes causing host inflammatory responses. Therefore, S. gordonii cell wall components act as virulence factors that often progressively develop diseases through overwhelming host responses.
  • 2.1K
  • 29 Dec 2020
Topic Review
Methicilin-Susceptible Staphylococcus aureus
Antibiotic resistance is a global health challenge nowadays, and methicillin-sensitive Staphylococcus aureus (MSSA) is a skin infection presents as pimples, boils, abscesses, or infected cuts and is not resistant to certain antibiotics. MSSA affects people of all ages and is known to cause epidemics among sports teams, families, prison inmates, and people who live and work in close quarters and is a global health challenge nowadays, creating problems in antibiotic therapy.
  • 2.1K
  • 10 Nov 2020
Topic Review
Acquired Cytomegalovirus Infection Hearing Loss
Congenital cytomegalovirus (CMV) infection induces a clinical syndrome usually associated with hearing loss. However, the effect of acquired CVM infection in adults and children has not been clearly defined.
  • 2.1K
  • 28 Dec 2020
Topic Review
Tetraspanins of extracellular vesicles
Tetraspanins are transmembrane proteins with ability to interact with each other and with other non-tetraspanin partners, building up a complex called tetraspanin web. This dynamic structure participates in many cellular processes. Although currently, the tetraspanin proteins found in extracellular vesicles are mostly applied as markers, increasing evidence points to their role in extracellular vesicle biogenesis, cargo selection, cell targeting, and cell uptake under both physiological and pathological conditions.
  • 2.1K
  • 02 Nov 2020
Topic Review
Bush Encroachment in Namibia
Bush encroachment is a natural phenomenon characterised by the excessive expansion of bush at the expense of other plant species, especially grasses. Bush encroachment is estimated to affect up to 45 million ha of Namibian land and has severe negative consequences on key Ecosystem services, especially agricultural productivity and groundwater recharge. Agricultural productivity in Namibia has declined by two thirds throughout the past decades, mainly due to the negative impact of bush encroachment. The phenomenon affects both commercial and communal farming in Namibia, mostly the central, eastern and north-eastern regions.
  • 2.1K
  • 23 Nov 2022
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