Topic Review
Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a regenerative microenvironment that has an excellent potential for tissue regeneration.
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  • 20 Jan 2021
Topic Review
MMP-13 in Osteoarthritis Treatment
Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase-13 (MMP-13) is the primary MMP involved in cartilage degradation through its particular ability to cleave type II collagen. Hence, it is an attractive target for the treatment of OA.
  • 2.5K
  • 07 May 2021
Topic Review
Memory Span
In psychology and neuroscience, memory span is the longest list of items that a person can repeat back in correct order immediately after presentation on 50% of all trials. Items may include words, numbers, or letters. The task is known as digit span when numbers are used. Memory span is a common measure of working memory and short-term memory. It is also a component of cognitive ability tests such as the WAIS. Backward memory span is a more challenging variation which involves recalling items in reverse order.
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  • 20 Oct 2022
Topic Review
Sperm Cryopreservation in Ruminant Species
Sperm cryopreservation is a powerful tool to preserve threatened animal species or for livestock breeding. However, this process is not free of disadvantages. Thus, during the cryopreservation process a significant amount of sperm suffers considerable cryodamage, which may affect sperm quality and fertility. Recently, the use of different “omics” technologies in sperm cryobiology, especially proteomics studies, has led to a better understanding of the molecular modifications induced by sperm cryopreservation, facilitating the identification of different freezability biomarkers and certain proteins that can be added before cryopreservation to enhance sperm cryosurvival. This entry provides an updated overview of the molecular mechanism involved in sperm cryodamage, as well as the molecular aspects of those novel strategies that have been developed to reduce sperm cryodamage, including  including new cryoprotectants, antioxidants, proteins, nanoparticles and vitrification.
  • 2.5K
  • 29 Oct 2020
Topic Review
Frying
Frying is one of the oldest unit operations to produce food products with a crisp texture, an aromatic flavour and a golden-brown colour. Deep-fried foods such as French fries, potato/veggie crisps are popular among consumers. Detailed insights into the frying process in terms of heat, mass (water and oil) and momentum transfers are outlined in this entry.
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  • 28 Jul 2020
Topic Review
East African Lion
The East African lion is a Panthera leo melanochaita population in East Africa. During the 20th century, lion populations in this part of Africa became fragmented and declined in several range countries due to loss of habitat and prey base, poaching and killing of lions to protect livestock and human life. In 2005, a Lion Conservation Strategy was developed for East and Southern Africa. Today, lion populations are stable only in large protected area complexes. The scientific name P. l. melanochaita was proposed for the Cape lion in 1842 that was eradicated in the mid-19th century. P. l. melanochaita differs genetically from P. leo leo; the two subspecies probably diverged at least 50,000 years ago.
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  • 01 Dec 2022
Topic Review
Odor Compounds in Meat
The volatile composition and odor of meat and meat products is based on the precursors present in the raw meat. These are influenced by various pre-slaughter factors (species, breed, sex, age, feed, muscle type). Furthermore, post-mortem conditions (chiller aging, cooking conditions, curing, fermentation, etc.) determine the development of meat volatile organic compounds (VOCs).
  • 2.5K
  • 08 Nov 2022
Topic Review
Amino Acid Catabolism
Amino acids have been extensively studied in nutrition, mainly as key elements for maintaining optimal protein synthesis in the body as well as precursors of various nitrogen-containing compounds. However, it is now known that amino acid catabolism is an important element for the metabolic control of different biological processes, although it is still a developing field to have a deeper understanding of its biological implications. The mechanisms involved in the regulation of amino acid catabolism now include the contribution of the gut microbiota to amino acid oxidation and metabolite generation in the intestine, the molecular mechanisms of transcriptional control, and the participation of specific miRNAs involved in the regulation of amino acid degrading enzymes. In addition, molecules derived from amino acid catabolism play a role in metabolism as they are used in the epigenetic regulation of many genes.
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  • 02 Aug 2023
Topic Review
Glossary of Bird Terms
The following is a glossary of common English language terms used in the description of birds—warm-blooded vertebrates of the class Aves and the only living dinosaurs, characterized by feathers, the ability to fly in all but the approximately 60 extant species of flightless birds, toothless, beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart and a strong yet lightweight skeleton. Among other details such as size, proportions and shape, terms defining bird features developed and are used to describe features unique to the class—especially evolutionary adaptations that developed to aid flight. There are, for example, numerous terms describing the complex structural makeup of feathers (e.g., barbules, rachides and vanes); types of feathers (e.g., filoplume, pennaceous and plumulaceous feathers); and their growth and loss (e.g., colour morph, nuptial plumage and pterylosis). There are thousands of terms that are unique to the study of birds. This glossary makes no attempt to cover them all, concentrating on terms that might be found across descriptions of multiple bird species by bird enthusiasts and ornithologists. Though words that are not unique to birds are also covered, such as "back" or "belly", they are defined in relation to other unique features of external bird anatomy, sometimes called "topography". As a rule, this glossary does not contain individual entries on any of the approximately 9,700 recognized living individual bird species of the world.
  • 2.5K
  • 09 Nov 2022
Topic Review
Food Waste Used for the Cultivation of Mushroom
Pleurotus ostreatus (P. ostreatus) is considered a high-quality food, rich in proteins and bioactive compounds important for maintaining human health. Lately, a commonly used substrate for oyster mushroom cultivation—wheat straw, is more often replaced by alternative cellulose substrates originated from the agricultural and food industry. Utilization of wastes for mushroom cultivation has its added value: sustainable food waste management, production of high-quality food from low quality waste, as well as solving environmental, economic and global issues.
  • 2.5K
  • 15 Nov 2022
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