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Topic Review
Mycotoxin Control in Foods
Mycotoxins are the most well-known food contaminants causing significant damage to both human and animal health. The main producers of mycotoxins are the fungi of the genera of Aspergillus, Fusarium, Penicillium, Claviceps and Alternaria. Due to the serious toxicological effects of consuming mycotoxin contaminated foods, it is necessary to control them. In order to control mycotoxin contamination, two key strategies are followed.These strategies mainly focus on the prevention of mycotoxins and detoxification. The implementation of pre- and post-harvest control systems includes good agricultural practices (GAPs), good manufacturing practices (GMPs), appropriate environmental factors, favorable storage practices and biological, chemical and physical methods as decontamination and detoxification strategies.
  • 2.9K
  • 27 Aug 2020
Topic Review
Lysyl oxidase like 2
LOXL2 is a key enzyme that catalyzes the cross-linking of collagen fibers and forms an integral part in collagen homeostasis. It is thus needed for normal functioning of the myocardium and is pertinent to cardiac remodeling [13]. Dysregulation of its expression is a major driver of muscle stiffness through induced cardiac fibrosis [24,25,43], which reduces cardiac output. In fact, it has been proposed that decreasing excessive collagen cross-linking would reduce myocardial fibrosis and stiffness and thereby improve heart function [44].
  • 2.9K
  • 20 Aug 2020
Topic Review
Epithelioid Cell
According to a common point of view Epithelioid cells (also called Epithelioid histiocytes) are derivatives of activated macrophages resembling epithelial cells.
  • 2.9K
  • 04 Nov 2022
Topic Review
YUC in Plant Developmental Processes
The YUC gene family encodes the rate-limiting enzymes in the TAA/YUC pathway, which stands as the primary endogenous auxin biosynthesis pathway in plants. YUC-medicated local auxin biosynthesis is important for establishing auxin gradient within cells/tissues and precisely regulating various major developmental processes such as root development, leaf morphogenesis, and reproductive development. The spatiotemporal expressions of different YUC genes enable function specialization across different plant species.
  • 2.9K
  • 23 Oct 2020
Topic Review
Gonadotropin-Releasing Hormone
The signals generated by the HPG axis, the main participants of which are gonadotropin-releasing hormone (GnRH), gonadotropins, and sex steroids, coordinate the development and functioning of the immune system, and immunomediators, in particular, cytokines and thymic peptides, influence the HPG axis.
  • 2.9K
  • 08 Jan 2021
Topic Review
Species Problem
The species problem is the set of questions that arises when biologists attempt to define what a species is. Such a definition is called a species concept; there are at least 26 recognized species concepts. A species concept that works well for sexually reproducing organisms such as birds is useless for species that reproduce asexually, such as bacteria. The scientific study of the species problem has been called microtaxonomy. One common, but sometimes difficult, question is how best to decide which species an organism belongs to, because reproductively isolated groups may not be readily recognizable, and cryptic species may be present. There is a continuum from reproductive isolation with no interbreeding, to panmixis, unlimited interbreeding. Populations can move forward or backwards along this continuum, at any point meeting the criteria for one or another species concept, and failing others. Many of the debates on species touch on philosophical issues, such as nominalism and realism, and on issues of language and cognition. The current meaning of the phrase "species problem" is quite different from what Charles Darwin and others meant by it during the 19th and early 20th centuries. For Darwin, the species problem was the question of how new species arose. Darwin was however one of the first people to question how well-defined species are, given that they constantly change.
  • 2.9K
  • 02 Nov 2022
Topic Review
Basal Ganglia in Neurometabolic Diseases
Diseases primarily affecting the basal ganglia in children result in characteristic disturbances of movement and muscle tone. Both experimental and clinical evidence indicates that the basal ganglia also play a role in higher mental states. The basal ganglia can be affected by neurometabolic, degenerative diseases or other conditions from which they must be differentiated. Neuroradiological findings in basal ganglia diseases are also known. However, they may be similar in different diseases. Their assessment in children may require repeated MRI examinations depending on the stage of brain development (mainly the level of myelination). A large spectrum of pathological changes in the basal ganglia in many diseases is caused by their vulnerability to metabolic abnormalities and chemical or ischemic trauma. The diagnosis is usually established by correlation of clinical and radiological findings. Neuroimaging of basal ganglia in neurometabolic diseases is helpful in early diagnosis and monitoring of changes for optimal therapy.
  • 2.9K
  • 20 Nov 2020
Topic Review
Haze in Beer
Beer is one of the oldest and also most widely consumed alcoholic beverages. It is a kind of colloid solution with complex composition and weak stability. The haze formation in beer is a serious quality problem, as it primarily affects the shelf life and flavor of beer. Hazes are caused by suspended insoluble particles of colloidal or larger size that can be perceived visually or by instruments.
  • 2.9K
  • 06 Jan 2022
Topic Review Peer Reviewed
Serum Albumin
Being one of the most abundant proteins in human and other mammals, albumin plays a crucial role in transporting various endogenous and exogenous molecules and maintaining of colloid osmotic pressure of the blood. It is not only the passive but also the active participant of the pharmacokinetic and toxicokinetic processes possessing a number of enzymatic activities. A free thiol group of the albumin molecule determines the participation of the protein in redox reactions. Its activity is not limited to interaction with other molecules entering the blood: of great physiological importance is its interaction with the cells of blood, blood vessels and also outside the vascular bed. This topic review contains data on the enzymatic, inflammatory and antioxidant properties of serum albumin. 
  • 2.8K
  • 13 Apr 2022
Topic Review
Wild Food Plants
Wild food plants (WFPs) are generally considered species that grow spontaneously in self-sustaining populations outside cultivated areas, in field margins, forests, woodland, grassland, and wetlands (e.g., paddy fields), independently of human activity. However, the distinction between “wild” and “cultivated” or “domesticated” is not so clear-cut and many wild food plants fall somewhere in between these two extremes depending on the degree of human intervention and management. Semi-domesticated species, in addition to economically important non-timber forest food products, such as açaí berries and Brazil nuts, can also be considered "wild" to some extent as they grow naturally in forest with limited management or human intervention. As they are often wild relatives of domesticated species, WFPs have potential for domestication and can provide a pool of genetic resources for hybridization and selective breeding.
  • 2.8K
  • 13 May 2024
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