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Topic Review
Hp-NCL Network in Routing Encoding
Goal-directed navigation is a crucial behavior for the survival of animals, especially for the birds having extraordinary spatial navigation ability. In neural mechanism of the goal-directed behavior, especially involving the information encoding mechanism of the route, the hippocampus (Hp), nidopallium caudalle (NCL) and their local networks of the avian brain play important roles.
  • 1.2K
  • 09 Nov 2020
Topic Review
Illicium verum Hook f. (Star Anise)
Illicium verum Hook f. (star anise) is considered an important species in Traditional Chinese Medicine and is also used in contemporary medicine in East Asian countries. It occurs in natural habitats in southeastern parts of China and Vietnam, and is cultivated in various regions in China. The raw materials—Anisi stellati fructus and Anisi stellati aetheroleum obtained from this species exhibit expectorant and spasmolytic activities. The European Pharmacopoeia (4th edition) indicates that these raw materials have been used in allopathy since 2002. The biological activities of the above-mentioned raw materials are determined by the presence of valuable secondary metabolites such as monoterpenoids, sesquiterpenoids, phenylpropanoids, and flavonoids. Recent pharmacological studies on fruit extracts and the essential oil of this species have confirmed their antibacterial, antifungal, anti-inflammatory, and antioxidant activities and thus their medicinal and cosmetic value.
  • 1.2K
  • 28 Jan 2022
Biography
Jemima Wilkinson
The Public Universal Friend (born Jemima Wilkinson; November 29, 1752 – July 1, 1819) was an American preacher born in Cumberland, Rhode Island, to Quaker parents. Wilkinson suffered a severe illness in 1776 and reported having died and been reanimated as a genderless evangelist named the Public Universal Friend, and afterward shunned both birth name and gendered pronouns. In androgynous cloth
  • 1.2K
  • 09 Dec 2022
Topic Review
Precision Agriculture
According to a recent definition of Precision Agriculture (PA), developed by the International Society of Precision Agriculture, the term refers to a management strategy, which uses acquisition, processing, analysis, and combination with other information of temporal, spatial, and other data in order to facilitate decision-making based on the estimated variability. 
  • 1.2K
  • 08 Feb 2021
Topic Review
NLRP3 Inflammasome in Neurodegenerative
Inflammasomes are intracellular multiprotein complexes in the cytoplasm that regulate inflammation activation in the innate immune system in response to pathogens and to host self-derived molecules. The NLRP3 belongs to the subfamily of NLRP which activates caspase 1, thus causing the production of proinflammatory cytokines (interleukin 1β and interleukin 18) and pyroptosis. This inflammasome is involved in multiple neurodegenerative and metabolic disorders including Alzheimer’s disease, multiple sclerosis, type 2 diabetes mellitus, and gout. 
  • 1.2K
  • 25 May 2022
Topic Review
T-Cell Receptor Repertoire Sequencing and Its Applications
The immune system is a dynamic feature of each individual and a footprint of our unique internal and external exposures. Indeed, the type and level of exposure to physical and biological agents shape the development and behavior of this complex and diffuse system. Many pathological conditions depend on how our immune system responds or does not respond to a pathogen or a disease or on how the regulation of immunity is altered by the disease itself. T-cells are important players in adaptive immunity and, together with B-cells, define specificity and monitor the internal and external signals that our organism perceives through its specific receptors, TCRs and BCRs, respectively. Today, high-throughput sequencing (HTS) applied to the TCR repertoire has opened a window of opportunity to disclose T-cell repertoire development and behavior down to the clonal level. Although TCR repertoire sequencing is easily accessible today, it is important to deeply understand the available technologies for choosing the best fit for the specific experimental needs and questions. Here, an updated overview of TCR repertoire sequencing strategies, providers and applications to infectious diseases and cancer to guide researchers’ choice through the multitude of available options is provided. The possibility of extending the TCR repertoire to HLA characterization will be of pivotal importance in the near future to understand how specific HLA genes shape T-cell responses in different pathological contexts and will add a level of comprehension that was unthinkable just a few years ago.
  • 1.2K
  • 24 Aug 2022
Topic Review
Mushroom Biotechnology
A mushroom is the fruit body of a fungus. There are 44,000 known species in the fungi kingdom, but not all of them produce mushrooms. Fungi lack chlorophyll and are heterotrophic organisms that break down organic matter in various ways. Mushrooms have always been an important source of food, with high nutritional value and medicinal attributes. With the use of biotechnological applications, mushrooms have gained further attention as a source of healthy food and bioenergy. Mushroom biotechnology is defined as the science in which mushrooms are included in processes like bioconversion, biorefining, bioremediation, and biodegradation.
  • 1.2K
  • 25 Jul 2023
Topic Review
Phytosterols
Phytosterols are important constituents of plant cells structural analogous of mammalian cholesterol, that have been shown to exert very important biological effects, such as hypocholesterolemic, antidiabetic, and antioxidant activities in the human body.
  • 1.2K
  • 28 Oct 2020
Topic Review
Aryl Hydrocarbon Receptor and Autism
AhR is a ligand-activated transcription factor that belongs to basic-helix-loop-helix (bHLH)/Per-ARNT-Sim (PAS) family, which is involved in the regulation of cell differentiation, proliferation, and cancer imitation. AhR plays an important role in various physiological pathways, including host defense, immunity, stem cell maintenance, cell differentiation, and xenobiotic metabolism. It was initially believed that AhR is activated only by a group of environmental pollutants, such as polycyclic aromatic hydrocarbons (PAHs).
  • 1.2K
  • 28 Sep 2021
Topic Review
Camel Milk Fat
There are two species of camels: one-humped camels (Camelus dromedarius) and two-humped camels (Camelus bactrianus). Camel milk (CM) is an essential food source in arid and semi-arid areas, as cow milk is not always available in these areas due to a lack of adaptation mechanisms. Despite these conditions, CM has been considered as one of the best alternatives to feed adults and infants, as well as for the production of many dairy products such as yogurt, cheese, cream, and butter.
  • 1.2K
  • 24 Sep 2021
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