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Topic Review
XMEN
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia (typically known by the acronym XMEN) is a disorder that affects the immune system in males. 
  • 798
  • 04 Jan 2021
Topic Review
Xishuangbanna Cucumber: Current Status and Future Prospects
The Xishuangbanna (XIS) cucumber is an important botanical variety, accumulating high levels of β-carotene (700 μg/100 g) in the endocarp of mature fruit compared with normal green/white flesh types (25–50 μg/100 g, fresh weight). β-carotene is an essential precursor of provitamin A synthesis required for human health, thus XIS cucumber is an appealing germplasm for vitamin A breeding programs.
  • 699
  • 17 Feb 2022
Topic Review
Xique-Xique Juice Functional Bevereage
Food market interest for functional beverages has increased in the last years, especially for those elaborated with unconventional matrices, such as exotic fruits, succulent plants and cacti. Xique-xique (Pilosocereus gounellei), from the Cactaceae family, is a species endemic from Brazil, with a large potential for prospection of bioactive compounds. Therefore, this study aimed to elaborate a potentially functional beverage with xique-xique cladode juice, and to evaluate its physicochemical parameters, phytochemical profile and antioxidant properties.
  • 559
  • 09 Sep 2021
Topic Review
Xia-Gibbs Syndrome
Xia-Gibbs syndrome is a neurological disorder characterized by weak muscle tone (hypotonia), mild to severe intellectual disability and delayed development.
  • 939
  • 24 Dec 2020
Topic Review
Xeroderma Pigmentosum
Xeroderma pigmentosum, which is commonly known as XP, is an inherited condition characterized by an extreme sensitivity to ultraviolet (UV) rays from sunlight. This condition mostly affects the eyes and areas of skin exposed to the sun. Some affected individuals also have problems involving the nervous system. The signs of xeroderma pigmentosum usually appear in infancy or early childhood. Many affected children develop a severe sunburn after spending just a few minutes in the sun. The sunburn causes redness and blistering that can last for weeks. Other affected children do not get sunburned with minimal sun exposure, but instead tan normally. By age 2, almost all children with xeroderma pigmentosum develop freckling of the skin in sun-exposed areas (such as the face, arms, and lips); this type of freckling rarely occurs in young children without the disorder. In affected individuals, exposure to sunlight often causes dry skin (xeroderma) and changes in skin coloring (pigmentation). This combination of features gives the condition its name, xeroderma pigmentosum.  
  • 575
  • 24 Dec 2020
Topic Review
Xenoestrogens and Phytoestrogens in Cancers
According to Global Cancer Statistics 2020, the burden of cancer incidence and mortality is rapidly growing worldwide. The epidemiological features of cancer reflect both the aging and growth of the population and the changes in the prevalence and distribution of the main cancer risk factors, several of which are particularly associated with the environment. Exogenous estrogens, such as synthetic industrial estrogenic compounds (xenoestrogens) and estrogenic molecules from plants (phytoestrogens), are environmental factors that potentially cause various cancers through their interactions with cellular signaling processes involving estrogen signaling pathways.
  • 449
  • 25 Aug 2021
Topic Review
Xenobiotic Pollution and Its Impact on the Environment
In the industrial revolution and urbanization era, the global environment’s poisoning by a complex mixture of xenobiotics has become a major environmental threat worldwide. Xenobiotic contaminants such as azodyes, phenolics, polycyclic aromatic hydrocarbons (PAHs), halogenated compounds, personal care products (PCPs), pharmaceuticals’ active compounds (PhACs), pesticides, nitroaromatic compounds, triazines, and chlorinated compounds adversely affect the environment by their long-term persistence and slow or no biodegradation in the ecosystems. Xenobiotic pollution of the environment is a global concern caused by anthropogenic activities such as urbanization and population expansion. The enormous amounts of harmful compounds released into the environment result in widespread ecosystem contamination. Prominent substances such as polycyclic aromatic hydrocarbons, heavy metal ions, pesticides, fertilizers, and oil derivatives are found in soil, sediment, and water. 
  • 4.9K
  • 07 Sep 2022
Topic Review
XDH Gene
Xanthine dehydrogenase
  • 474
  • 24 Dec 2020
Topic Review
Xanthomonas campestris
Xanthomonas campestris pv. campestris (Xcc) is a Gram-negative, aerobic, vascular, and motile bacterium with a single flagellum, which causes the disease identified as black rot in Brassica crops.
  • 978
  • 30 Aug 2021
Topic Review
Xanthohumol Is a Potent Pan-Inhibitor of Coronaviruses
Coronaviruses cause diseases in humans and livestock. The SARS-CoV-2 is infecting millions of human beings, with high morbidity and mortality worldwide. The main protease (Mpro) of coronavirus plays a pivotal role in viral replication and transcription, which, in theory, is an attractive drug target for antiviral drug development. It has been extensively discussed whether Xanthohumol is able to help COVID-19 patients. Here, researchers report that Xanthohumol, a small molecule in clinical trials from hops (Humulus lupulus), was a potent pan-inhibitor for various coronaviruses by targeting Mpro, for example, betacoronavirus SARS-CoV-2 (IC50 value of 1.53 μM), and alphacoronavirus PEDV (IC50 value of 7.51 μM). Xanthohumol inhibited Mpro activities in the enzymatical assays, while pretreatment with Xanthohumol restricted the SARS-CoV-2 and PEDV replication in Vero-E6 cells. Therefore, Xanthohumol is a potent pan-inhibitor of coronaviruses and an excellent lead compound for further drug development.
  • 485
  • 22 Dec 2021
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