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Tang, P. XMEN. Encyclopedia. Available online: https://encyclopedia.pub/entry/6067 (accessed on 20 September 2026).
Tang P. XMEN. Encyclopedia. Available at: https://encyclopedia.pub/entry/6067. Accessed September 20, 2026.
Tang, Peter. "XMEN" Encyclopedia, https://encyclopedia.pub/entry/6067 (accessed September 20, 2026).
Tang, P. (2021, January 04). XMEN. In Encyclopedia. https://encyclopedia.pub/entry/6067
Tang, Peter. "XMEN." Encyclopedia. Web. 04 January, 2021.
Copy Citation
X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection, and neoplasia (typically known by the acronym XMEN) is a disorder that affects the immune system in males.
genetic conditions
References
- Brandao K, Deason-Towne F, Perraud AL, Schmitz C. The role of Mg2+ in immunecells. Immunol Res. 2013 Mar;55(1-3):261-9. doi: 10.1007/s12026-012-8371-x.Review.
- Chaigne-Delalande B, Li FY, O'Connor GM, Lukacs MJ, Jiang P, Zheng L, Shatzer A, Biancalana M, Pittaluga S, Matthews HF, Jancel TJ, Bleesing JJ, Marsh RA,Kuijpers TW, Nichols KE, Lucas CL, Nagpal S, Mehmet H, Su HC, Cohen JI, Uzel G,Lenardo MJ. Mg2+ regulates cytotoxic functions of NK and CD8 T cells in chronicEBV infection through NKG2D. Science. 2013 Jul 12;341(6142):186-91. doi:10.1126/science.1240094.
- Li FY, Chaigne-Delalande B, Kanellopoulou C, Davis JC, Matthews HF, Douek DC, Cohen JI, Uzel G, Su HC, Lenardo MJ. Second messenger role for Mg2+ revealed byhuman T-cell immunodeficiency. Nature. 2011 Jul 27;475(7357):471-6. doi:10.1038/nature10246.
- Li FY, Chaigne-Delalande B, Su H, Uzel G, Matthews H, Lenardo MJ. XMENdisease: a new primary immunodeficiency affecting Mg2+ regulation of immunityagainst Epstein-Barr virus. Blood. 2014 Apr 3;123(14):2148-52. doi:10.1182/blood-2013-11-538686.
- Li FY, Lenardo MJ, Chaigne-Delalande B. Loss of MAGT1 abrogates the Mg2+ flux required for T cell signaling and leads to a novel human primaryimmunodeficiency. Magnes Res. 2011 Sep;24(3):S109-14. doi: 10.1684/mrh.2011.0286.Review.
- Wolf FI, Trapani V. MagT1: a highly specific magnesium channel with important roles beyond cellular magnesium homeostasis. Magnes Res. 2011 Sep;24(3):S86-91.doi: 10.1684/mrh.2011.0288. Review.
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