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Topic Review
Biography
Topic Review
Suture Mesenchymal Stem Cells
Suture mesenchymal stem cells (SuSCs), a heterogeneous stem cell population, belong to mesenchymal stem cells (MSCs) or skeletal stem cells (SSCs), with the ability to self-renew and undergo multi-lineage differentiation. Unlike the well-established perivascular niche of SSCs in the long bone, stem cells of the cranial bone are generally located and confined within the cranial suture mesenchyme, subsequently defined as SuSCs. In the long bone, SSCs play an essential role in plenty of physiological processes, such as growth and development, life-long homeostasis, and fracture healing. Similarly, as the major stem cell population of cranial bones, the physiological significance of SuSCs is undoubted and self-evident.
1.5K
22 Sep 2021
Topic Review
Cannabinoid Receptors
Spermatogenesis is a highly coordinated process that begins with division of spermatogonia, followed by meiosis to produce haploid spermatids, and finally the differentiation of haploid spermatids into mature spermatozoa. Several stages of male germ cell development are regulated by epigenetic mechanisms that are important for correct gamete development and functions. The use of Cannabis sativa has been demonstrated to induce spermatogenesis dysfunctions. Cannabis sativa (Marijuana) exerts its effect by binding to and activating cannabinoid receptors CB1 and CB2 . In males, both the receptors CB1 and CB2, are involved in male germ cell development. Here we will discuss on the importance of cannabinoid receptors signaling in the regulation of several stages of male germ cell development and their role in mediating epigenetic modifications that may be transmitted to the next generation by sperm.
1.5K
31 Jul 2020
Topic Review
Dendrocalamus asper and Related Bamboos
Bamboos represent an emerging forest resource of economic significance and provide an avenue for sustainable development of forest resources. The development of the commercial bamboo industry is founded upon efficient molecular and technical approaches for the selection and rapid multiplication of elite germplasm for its subsequent propagation via commercial agro-forestry business enterprises.
1.5K
08 Nov 2021
Biography
Anthony Fauci
Anthony Stephen Fauci OMRI (born December 24, 1940) is an American physician-scientist and immunologist serving as the Director of the National Institute of Allergy and Infectious Diseases (NIAID) and the Chief Medical Advisor to the President. As a physician with the National Institutes of Health (NIH), Fauci has served the American public health sector in various capacities for more than fift
1.5K
15 Nov 2022
Topic Review
Alternative Oxidase
The interaction of the alternative oxidase (AOX) pathway with nutrient metabolism is important for understanding how respiration modulates ATP synthesis and carbon economy in plants under nutrient deficiency. Although AOX activity reduces the energy yield of respiration, this enzymatic activity is upregulated under stress conditions to maintain the functioning of primary metabolism. The in vivo metabolic regulation of AOX activity by phosphorus (P) and nitrogen (N) and during plant symbioses with Arbuscular mycorrhizal fungi (AMF) and Rhizobium bacteria is still not fully understood. We highlight several findings and open questions concerning the in vivo regulation of AOX activity and its impact on plant metabolism during P deficiency and symbiosis with AMF. We also highlight the need for the identification of which metabolic regulatory factors of AOX activity are related to N availability and nitrogen‐fixing legume‐rhizobia symbiosis in order to improve our understanding of N assimilation and biological nitrogen fixation.
1.5K
27 Oct 2020
Topic Review
Probiotics in Poultry Nutrition
Probiotics are live bacteria, fungi, or yeasts that supplement the gastrointestinal flora and help to maintain a healthy digestive system, thereby promoting the growth performance and overall health of poultry.
1.5K
06 Nov 2020
Topic Review
Cryptomeria japonica
Cryptomeria japonica, a commercially important tree throughout Asia and the Azores Archipelago (Portugal), is currently waste/by-products of wood processing that can be converted into eco-friendly and high added-value products, such as essential oils (EOs), with social, environmental and economic impacts.
1.5K
07 Dec 2021
Topic Review
Neurodegeneration in Multiple Sclerosis
Neurodegeneration in multiple sclerosis is believed to underlie disease progression and permanent disability. Many mechanisms of neurodegeneration in MS have been proposed, such as mitochondrial dysfunction, oxidative stress, neuroinflammation, and most recently RNA-binding protein dysfunction. Studying RNA-binding protein dysfunction addresses a gap in our understanding of the pathogenesis of MS, which may allow for novel therapies to be generated to attenuate neurodegeneration before irreversible central nervous system damage occurs.
1.5K
29 Jun 2021
Topic Review
Biological Roles and Applications of Aconitic Acid
Aconitic acid (propene-1,2,3-tricarboxylic acid) is the most prevalent 6-carbon organic acid that accumulates in sugarcane and sweet sorghum. As a top value-added chemical, aconitic acid may function as a chemical precursor or intermediate for high-value downstream industrial and biological applications. These downstream applications include use as a bio-based plasticizer, cross-linker, and the formation of valuable and multi-functional polyesters that have also been used in tissue engineering. Aconitic acid also plays various biological roles within cells as an intermediate in the tricarboxylic acid cycle (TCA) and in conferring unique survival advantages to some plants as an antifeedant, antifungal, and means of storing fixed pools of carbon. Aconitic acid has also been reported as a fermentation inhibitor, anti-inflammatory, and a potential nematicide.
1.5K
16 Mar 2022
Topic Review
Thin Filament Structure and Assembly
The actin containing tropomyosin and troponin decorated thin filaments form one of the crucial components of the contractile apparatus in muscles. The thin filaments are organized into densely packed lattices interdigitated with myosin-based thick filaments. The crossbridge interactions between these myofilaments drive muscle contraction, and the degree of myofilament overlap is a key factor of contractile force determination.
1.5K
18 May 2022
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