Topic Review
Mosquito-Borne Viruses in Iran
Mosquito-borne diseases (MBDs) have global public health implications to both humans and animals, making it a One Health priority concern. Ongoing climatic change creates favourable conditions for the emergence of exotic MBDs in previously disease-free areas. 
  • 209
  • 08 Jan 2024
Topic Review
Heterologous Production of Crocins in Different Species
Crocin is one of the most valuable components of the Chinese medicinal plant Crocus sativus and is widely used in the food, cosmetics, and pharmaceutical industries. Traditional planting of C. sativus is unable to fulfill the increasing demand for crocin in the global market, however, such that researchers have turned their attention to the heterologous production of crocin in a variety of hosts. 
  • 265
  • 08 Jan 2024
Topic Review
The VBNC State in Beneficial Bacteria
Bacteria in the viable but non-culturable (VBNC) state exhibit a remarkable phenomenon: they are unable to grow and form colonies on conventional culture media, yet they remain alive and able to restart their metabolic activity. Cells in this status typically display reduced levels of metabolic activity and undergo significant metabolic alterations, such as reductions in nutrient transport and respiration rates and macromolecular synthesis, and form resistance structures similar to spores. However, a feature that distinguishes the VNBC state is the continuous gene expression within these cells.
  • 306
  • 08 Jan 2024
Topic Review
β-1,4-GalT-V and Cancer
β-1,4-GalTs are a family of glycosyltransferases, all having similar properties (i.e., they exclusively transfer galactose residues from a donor UDP-galactose via β-1,4 linkage to acceptor sugars, N-acetyl glucosamine (GlcNAc),glucose (Gl)c, and xylose(Xyl), which can be components of protein or lipids that have different functions).
  • 200
  • 08 Jan 2024
Topic Review
DNA Methylation
DNA methylation is a key epigenetic signature implicated in regulation of gene expression that occurs predominantly within CpG dinucleotides.
  • 147
  • 08 Jan 2024
Topic Review
The Link between SARS-CoV-2 Infection and Renal Cancer
Cancer has been described as a risk factor for greater susceptibility to SARS-CoV-2 infection and severe COVID-19, mainly for patients with metastatic disease. Conversely, to that reported for most solid and hematological malignancies, the few available clinical studies reported that the infection did not increase the risk of death in renal cancer patients. The expression on proximal tubular renal cells of the key players in cellular viral uptake, ACE2, TMPRSS2, and NRP1, seems to be the mechanism for the direct kidney injury seen in patients with COVID-19. Data from The Cancer Genome Atlas and experimental analyses on various renal cancer cell lines demonstrated that the above-reported receptors/cofactors are maintained by renal cancer cells. However, whether SARS-CoV-2 infection directly kills renal cancer cells or generates enhanced immunogenicity is a question worth investigating.
  • 141
  • 08 Jan 2024
Topic Review
Crop Fertigation in Closed Soilless Systems
Inappropriate fertilisation results in the pollution of water resources with nitrates and phosphates, eutrophication in surface water, emission of greenhouse gasses, and unwanted N deposition in natural environments, thereby harming the whole ecosystem. Cultivation in closed soilless systems entails recycling of the fertigation effluents thus eliminating nutrient emissions to the environment and concomitantly pollution of water resources with nitrates and phosphates.
  • 211
  • 08 Jan 2024
Topic Review
Droplet-Based Microfluidic High-Throughput Screening of Engineered Strains
Microfluidic technology has become an important high-throughput screening technology due to its fast speed, low cost, high automation, and high screening throughput, and it has developed rapidly. Droplet-based microfluidic high-throughput screening has been widely used in various fields, such as strain/enzyme activity screening, pathogen detection, single-cell analysis, drug discovery, and chemical synthesis, and has been widely applied in industries such as those involving materials, food, chemicals, textiles, and biomedicine. 
  • 174
  • 08 Jan 2024
Topic Review
Lactococcus lactis
Gram-positive cocci known as Lactococcus are found solely in pairs or in chains. They are catalase-negative, and facultatively anaerobic L-lactic acid is the main byproduct of the fermentation of glucose during the glycolytic pathway of L. lactis.
  • 216
  • 05 Jan 2024
Topic Review
New Foods in Enhancing Energy Security
Increasing energy security is a crucial component of achieving the Sustainable Development Goals (SDGs). Three main factors influence energy security: (1) the efficiency of resource use in energy production, (2) the extent of energy losses, and (3) the use of new energy sources. Novel food products can impact these factors. Assuring sustainable growth and development in the long run calls for technical, social, political, economic, ethical, and research integrity solutions to ensure a reliable supply of clean and affordable energy and nutritious food for everyone, which highly impact well-being and health.
  • 193
  • 05 Jan 2024
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