Topic Review
Pharmacological Update Properties of Aloe Vera Active Constituents
Aloe vera (Aloe barbadensis Miller, family Xanthorrhoeaceae) is a perennial green herb with bright yellow tubular flowers that is extensively distributed in hot and dry areas of North Africa, the Middle East of Asia, the Southern Mediterranean, and the Canary Islands.  Aloe vera has been traditionally used to treat skin injuries (burns, cuts, insect bites, and eczemas) and digestive problems because its anti-inflammatory, antimicrobial, and wound healing properties. 
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  • 27 Jul 2022
Topic Review
Technical Lignin
Lignin, the term commonly used in literature, represents a group of heterogeneous aromatic compounds of plant origin. 
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  • 16 Feb 2021
Topic Review
Rhizosphere
The rhizosphere serves as a hotspot for diverse microbial activity. It is an intricate ecosystem comprising nutrient-rich soil that surrounds the plant roots, which provides a pool for plant–microbe communication. The term “Rhizomicrobiome” is defined as a microbial community that is present in the rhizosphere. A variety of microorganisms reside within the rhizosphere, including bacteria, fungi, nematodes, protists, and invertebrates. Most of the microbiome studies within the context of rhizosphere signaling have been focused on the bacteria and fungi that make up the major portion of the rhizosphere microbiome.
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  • 17 May 2022
Topic Review
Diagnosis of Plant Virus Diseases
Among the plant pathogens, viruses (and viroids), which are transmitted by a living organism called a vector, are the major infectious agents that cause plant disease. Once a plant virus infects a susceptible host, it can spread to another plant by means of vector-mediated transmission (horizontally) or from parents to offspring (vertically). Since accurate diagnosis methods are of pivotal importance for viral diseases control, the current and emerging technologies for the detection of these plant pathogens are described.
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  • 27 Jan 2022
Topic Review
Resveratrol and Human Skin Lightening
Resveratrol is a polyphenol compound found in many edible plants such as Vitis vinifera, and its inhibitory effects on the catalytic activity, gene expression, and posttranslational modifications of tyrosinase, a key enzyme in the melanin biosynthetic pathway, provide a mechanistic basis for its antimelanogenic effects seen in melanocytic cells, three-dimensionally reconstituted skin models, and in vivo animal models. Recent clinical studies have supported the efficacy of resveratrol and its analogs, such as resveratryl triacetate (RTA) and resveratryl triglycolate (RTG), in human skin lightening. These findings suggest that resveratrol and its analogs are potentially useful as skin lightening agents in cosmetics.
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  • 29 Jul 2021
Topic Review
The Spemann Organizer
In 1924, to understand the processes involved in developmental biology, Spemann and Mangold transplanted a blastopore lip between different ectodermal regions of amphibian embryos. The transplanted dorsal tissue differentiated mostly into a notochord, while the ectoderm of the host dorsal tissue that was sitting above the transplanted region (blastopore lip) was induced and differentiated to form a Siamese twin containing dorsal tissues such as somites and a neural plate, which would form the central nervous system, forming the bulk of a second axis. The major findings were that the transplant had altered the fate of the overlying cells and that the neural folds were built from recipient cells and not donor cells. Spemann and Mangold discovered the organizing center in the dorsal blastopore lip of amphibians. This center consists of a cluster of cells in the developing embryo that have the ability to interact and instruct morphogenesis in the surrounding cells during gastrulation. When transplanted to the ventral side of the embryo, the center will induce the formation of a secondary axis, promoting the development of the central nervous system, organs, and tissues, as well as the formation of the main body axis. Spemann and Mangold found the first evidence of the organizing center, thereafter called the “Spemann organizer”, and its major role in the development of vertebrates. This discovery also introduced the concept of induction in embryonic development, which refers to the method used by specific cells to affect the fate of other embryonic cells. A major milestone had been achieved for developmental biology.
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  • 11 Nov 2021
Topic Review
Purple Non-Sulfur Bacteria
Photosynthetic bacteria (PSB) are procaryotes capable of carrying out photosynthesis by converting light energy into chemical energy. These photosynthetic bacteria can either grow in the presence or absence of oxygen (aerobic and anaerobic conditions) and can either use organic or inorganic substances as an electron donor to fix the atmospheric nitrogen (N2) and carbon dioxide (CO2). The purple non-sulfur bacteria belong to the anoxygenic group of PSB, and their major groups include Rhodopseudomonas spp. and Rhodobacter spp. They are naturally present in wastewater ponds, lagoons, lakes, sediments, wetland ecosystems, moist soils, hypersaline systems, and marine ecosystems. They possess versatile metabolic pathways and, therefore, are widely used in the livestock and fisheries industries , in bioremedial methods for heavy metals and sewage, and in biofuel production (electricity or photohydrogen). Studies have also shown that purple non-sulfur bacteria (PNSB) help boost soil fertility when applied directly to the soil, whereas PNSB applied to plants help improve crop growth and yield.
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  • 14 Oct 2022
Topic Review
Inositol Hexaphosphate (IP6)
Multiple human health-beneficial effects have been related to highly phosphorylated inositol hexaphosphate (IP6). This naturally occurring carbohydrate and its parent compound, myo-inositol (Ins), are abundantly present in plants, particularly in certain high-fiber diets, but also in mammalian cells, where they regulate important cellular functions. However, the striking and broad-spectrum anticancer activity of IP6, consistently demonstrated in different experimental models, has been in a spotlight of the scientific community dealing with the nutrition and cancer during the last several decades. First experiments were performed in colon cancer 30 years ago. Since then, it has been shown that IP6 reduces cell proliferation, induces apoptosis and differentiation of malignant cells with reversion to normal phenotype, affecting several critical molecular targets. Enhanced immunity and antioxidant properties also contribute to the tumor cell destruction. Although Ins possesses a modest anticancer potential, the best anticancer results were obtained from the combination of IP6 + Ins.
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  • 07 Jan 2021
Topic Review
Application of Nanoparticles on Plants as Fertilizers
Soil degradation has led to an imbalance between food and feed production, climate regulation, water retention and carbon storage in the ecosystem. On a larger scale, it has led to soil erosions and nutrient runoffs, leading to soil infertility, thus affecting human beings through malnutrition and other related diseases. To increase productivity and improve soil quality, fertilizers have been used for decades by farmers worldwide on degraded soils affected by human factors. However, their intensive usage has led to the pollution of both water and soil as the crop uses less than half of the applied amount; the other remaining amount is lost through photolysis, hydrolysis, leaching and microbial immobilization and degradation; thus, threatening the soil microorganisms, human health and the ecosystem, and reducing the profit margin of farmers.
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  • 04 Nov 2022
Topic Review Peer Reviewed
Mediterranean Diet
The Mediterranean diet is a food pattern incorporated into a set of lifestyle practices typical of Greece and Southern Italy in the early 1960s, where adult life expectancy was notably high, while rates of diet-related chronic diseases were low. The Mediterranean diet was described initially by the work of LG Allbaugh, commissioned by the Rockefeller foundation and the Greek government post-WW2 on the Greek island of Crete in 1948. The Mediterranean diet was accepted as Intangible Cultural Heritage of Humanity by UNESCO in 2013. The primary advantages of the Mediterranean diet include health benefits pertinent to cardiovascular, metabolic syndrome, and cognition.
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  • 13 Apr 2022
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