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Topic Review
Phages and Intestinal Dysbiosis
Gastrointestinal tract microbiota plays a key role in the regulation of the pathogenesis of several gastrointestinal diseases. In particular, the viral fraction, composed essentially of bacteriophages, influences homeostasis by exerting selective pressure on the bacterial communities living in the tract. The inflamed gut is associated with an SOS response regulated by an increase in resident intestinal pathogenic bacteria, loss of phage diversity, and induction of prophages.
  • 1.7K
  • 09 Nov 2020
Topic Review
Biological Activities of Chlorogenic Acids
The chlorogenic acids (CGAs) are a class of phenolic compounds widely distributed in various plants sources such as fruits, vegetables, coffee beans, tea, apples, and wine. CGAs are esters of quinic acid (QA) and one trans-cinnamic acid residue such as caffeic acid (CA), p-coumaric acid (p-CoA), and ferulic acid (FA), which are known as caffeoylquinic acids (CQAs), p-coumaroylquinic acids (p-CoQAs) and feruloylquinic acid (FQAs).
  • 1.7K
  • 10 Jun 2022
Topic Review
Chloroplasts in Plant Stress Responses
The chloroplast has a central position in oxygenic photosynthesis and primary metabolism. In addition to these functions, the chloroplast has recently emerged as a pivotal regulator of plant responses to abiotic and biotic stress conditions. Chloroplasts have their own independent genomes and gene-expression machinery and synthesize phytohormones and a diverse range of secondary metabolites, a significant portion of which contribute the plant response to adverse conditions.
  • 1.7K
  • 05 Jan 2022
Topic Review
Plasmonic biosensing schemes for virus
The uncertain proportions of pandemic outbreaks have triggered the need of reliable and cost-effective protocols easily adaptable to the changing virulence of virus strains. In recent years, plasmonic biosensors are being increasingly applied for clinical diagnosis of viral and other infectious diseases. Typical plasmonic biosensing strategies rely on the versatility of SPR and LSPR as label-free detection systems capable of monitoring binding interactions in a short period of time. Nevertheless, the incorporation of technological advancements has precipitated the development of nanomaterial-based applications for improving the sensitivity and specificity of classical configurations. The unique optical properties of plasmonic nanostructures has been exploited in combination with SERS colorimetric, fluorescence or luminescence enhancement for viral diagnosis. Likewise, the development of plasmonic virus sensing approaches has also benefitted from the variety of virus biomarkers. Thus, a high number of virus plasmonic biosensors have prompted the advance of novel functionalization strategies to achieve the effective coverage of the biological receptor while ensuring the affinity and specificity towards the target viral nucleic acids, proteins or whole virus. The huge potential for single virus detection along with the effectiveness and simplicity of current plasmonic configurations will impact on the routine surveillance of virus in clinical settings during this decade.
  • 1.7K
  • 27 Oct 2020
Topic Review
Trends in Bioenergy Production
A wide range of studies have been performed in the field of the usage of biomass for energy production, in order to contribute to the green transition from fossil fuels to renewable energies. Over the past 20 years (from 2000 to 2019), approximately 10,000 articles have been published in the “Agricultural and Biological Sciences” field on this theme, covering all stages of production—from the harvesting of crops to the particular type of energy produced. Articles were obtained from the SCOPUS database and examined with a text mining tool in order to analyze publication trends over the last two decades. Publications per year in the bioenergy theme have grown from 91 in 2000 to 773 in 2019. In particular the analyses showed how environmental aspects have increased their importance (from 7.3% to 11.8%), along with studies related to crop conditions (from 10.4% to 18.6%). Regarding the use of energy produced, growing trends were recognized for the impact of biofuels (mentions moved from 0.14 times per article in 2000 to 0.38 in 2019) and biogases (from 0.14 to 0.42 mentions).
  • 1.7K
  • 28 Aug 2020
Topic Review
Corneal Regenerative Approach
A transparent cornea is paramount for vision. Corneal opacity is one of the leading causes of blindness. Although conventional corneal transplantation has been successful in recovering patients’ vision, the outcomes are challenged by a global lack of donor tissue availability. Bioengineered corneal tissues are gaining momentum as a new source for corneal wound healing and scar management. Extracellular matrix (ECM)-scaffold-based engineering offers a new perspective on corneal regenerative medicine.
  • 1.7K
  • 11 Aug 2022
Topic Review
Plant-Based Diet
In recent decades, the food industry has been faced with new challenges and it has had to develop new types of diets and produce new types of foods that can slow down the spread of chronic diseases. The aim of our research is to identify the characteristics of plant-based nutrition based on international and Hungarian literature. The comprehensive analysis has been performed based on the theoretical model called Theory of Planned Behavior, in the course of which the perceived and objective benefits of and barriers to the conversion to a plant-based diet have been examined. According to our results, the main benefits of plant-based nutrition are its many factors associated with a reduction in risk of developing numerous chronic diseases. This is followed by benefits of well-being and satisfaction, followed by ethical and environmental benefits. The most commonly reported inhibitory factor of a vegetarian diet is the enjoyment of eating meat and the difficulty in giving up meat consumption. This is followed by health considerations, e.g., lack of various ingredients in foods. Convenience and taste factors are also important disincentives as well as the irrelevant nature of some plant-based nutrition information sources. Besides, social barriers, negative discrimination and negative effect of mental health associated with them can also be a hindrance, as can financial barriers. The classification developed during our analysis can serve as a relevant guideline for decision-makers, and also as a basis for further primary qualitative and quantitative research.
  • 1.7K
  • 27 Oct 2020
Topic Review
DPPH Radical Scavenging Assay
The 1,1-diphenyl-2-picrylhydrazil (DPPH) radical removal is one of the most widely applied and used methods in food and pharmaceutical applications. DPPH method gives a better response for mostly phenolic compounds and then for compounds with limited polarity. In the case of polar and phenolic compounds, adding water to the reaction medium, that is, aqueous methanol, gives better results. When testing low-polarity compounds, ethyl acetate with a radical is suitable. DPPH reaction rates depend on the steric accessibility of the radical site rather than the chemical properties of the tested antioxidant compounds. The rate at which DPPH reacts with antioxidants depends on the varying ratios of mixed single-electron transfer (SET) and hydrogen atom transfer (HAT) mechanisms. The reaction mechanisms of DPPH∙ scavenging and responses are modified by many environmental and experimental factors.
  • 1.7K
  • 08 Sep 2023
Topic Review
Chondrocytes
Chondrocytes are the cells found in cartilage that responsible for the production and maintenance of the cartilaginous matrix, which consists of collagen, proteoglycans, glycoproteins and hyaluronan. Autologous chondrocyte implantation (ACI) is a new treatment modality with the potential to promote regeneration of worn cartilage. ACI has been used to treat osteoarthritis (OA), a degenerative joint disease that affects many people worldwide. Human platelet lysate (HPL) has been identified as a potential replacement for foetal bovine serum (FBS) for the expansion of chondrocytes.
  • 1.7K
  • 05 Feb 2021
Topic Review
ARDS
Acute respiratory distress syndrome (ARDS) is a serious clinical illness, defined by severe hypoxemic respiratory failure, which continues to be associated with significant morbidity, mortality, and healthcare resource utilization. 
  • 1.7K
  • 16 Dec 2020
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