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All Topic Review Biography
Topic Review
Factors That Influence the Accuracy of Intraoral Scanners
Intraoral scanners (IOSs) have become increasingly popular in the field of dentistry for capturing accurate digital impressions of patients’ teeth and oral structures. The accuracy of intraoral scanning is influenced by various factors such as scanner selection, operator skill, calibration, patient’s oral anatomy, ambient conditions, and scanning aids. Maintaining updated software and understanding factors beyond scanner resolution are crucial for optimal accuracy. Conversely, smaller IOS tips, fast scanning speeds, and specific scanning patterns compromise the accuracy and precision. By understanding these factors, dental professionals can make more informed decisions and enhance the accuracy of IOSs, leading to improved final dental restorations.
  • 242
  • 08 Dec 2023
Topic Review
Extracellular Vesicles for Dental Pulp and Periodontal Regeneration
Extracellular vesicles (EVs) are lipid bound particles derived from their original cells, which play critical roles in intercellular communication through their cargoes, including protein, lipids, and nucleic acids. Status of EVs in pulp/periodontal tissue regeneration and the potential mechanisms are discussed.
  • 523
  • 10 Feb 2023
Topic Review
Excipients to Inhibit Efflux Transporters
Efflux transporters distributed at the apical side of human intestinal epithelial cells actively transport drugs from the enterocytes to the intestinal lumen, which could lead to extremely poor absorption of drugs by oral administration. Efflux transporters in the gastrointestinal tract mainly include P-gp, MRPs and BCRP.
  • 800
  • 17 Jun 2022
Topic Review
Essential Oils and the Oral Microbiome
The extensive use of antibiotics has resulted in the development of drug-resistant bacteria, leading to a decline in the efficacy of traditional antibiotic treatments. Essential oils (EOs) are phytopharmaceuticals, or plant-derived compounds, that possess beneficial properties such as anti-inflammatory, antibacterial, antimicrobial, antiviral, bacteriostatic, and bactericidal effects.
  • 849
  • 21 Feb 2023
Topic Review
Essential Oil-Based Mouthwashes
Essential oil (EO)-based mouthwashes have been used for oral health maintenance due to their antimicrobial and anti-inflammatory properties. The aim was to review clinical trials that assessed the role of EO-based mouthwashes in controlling gingivitis in patients undergoing fixed orthodontic treatment (OT).
  • 503
  • 29 Oct 2021
Topic Review
Engineering Principles for Clinicians
As innovation and especially the advent of customized prostheses has deeply modified many surgical procedures in our discipline, it is imperative for the contemporary surgeon to become aware of the impact that the MDR will have on many aspects, including the choice of the manufacturer, the evaluation of the devices, point-of-care 3D printing labs, and medical software.
  • 575
  • 16 Dec 2021
Topic Review
Endotoxin-Secreting Bacteria in Periodontal Disease
The LPS is recognized by the complex TLR4/MD2, mediated by CD14 and accessory protein LBP, which induces the activation of several transcriptional regulators like factor nuclear kB (NF-kB), activator protein 1 (AP-1) and interferon (IFN) regulatory factors, leading to the expression of genes involved in the host immune response.
  • 618
  • 13 Sep 2021
Topic Review
Endodontic–Periodontal Lesions
Endodontic–periodontal lesions (EPLs) are chronic inflammatory lesions in the mouth caused by multiple factors. Both periapical and marginal periodontitis are characterized by infection and inflammation around the affected teeth, suggesting that the theory of complex systems might describe the progression of EPL.
  • 666
  • 27 Oct 2022
Topic Review
Endodontic Regenerative Procedures in Necrotic Adult Teeth
Regenerative endodontic procedures (from now on REPs) have been defined as ‘biologically based procedures that intend to physiologically replace damaged tooth structures, including dentine and root, as well as cells of the pulp–dentin complex’. REPs were first exclusively developed for the treatment of immature teeth, with the purpose of achieving a complete root development. Nevertheless, these procedures can also restore tooth vitality and pulp functions thanks to the pulp tissue regeneration. Thus, sensibility, immunity, healing, and restorative properties of dental pulp would also be recovered, in turn reducing the chances of reinfection. For that reason, the feasibility of this treatment in mature teeth should be further studied, as until now, conservative treatment for irreversible necrosis or pulpitis has been limited to conventional endodontic therapy. 
  • 422
  • 16 May 2022
Topic Review
Endodontic Microsurgery of Mandibular Molars
Endodontic microsurgery is a highly predictable treatment option in most cases when conventional endodontic treatment is not feasible. 
  • 941
  • 22 Apr 2021
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