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Topic Review
Periodontitis in Systemic Sclerosis
Systemic sclerosis (SSc) is a chronic, autoimmune, multisystemic disease characterized by aberrant extracellular matrix protein deposition and extreme progressive microvasculopathy. These processes lead to damage within the skin, lungs, or gastrointestinal tract, but also to facial changes with physiognomic and functional alterations, and dental and periodontal lesions. Orofacial manifestations are common in SSc but are frequently overshadowed by systemic complications. In clinical practice, oral manifestations of SSc are suboptimally addressed, while their management is not included in the general treatment recommendations. Periodontitis is associated with autoimmune-mediated systemic diseases, including systemic sclerosis. In periodontitis, the microbial subgingival biofilm induces host-mediated inflammation with subsequent tissue damage, periodontal attachment, and bone loss. When these diseases coexist, patients experience additive damage, increasing malnutrition, and morbidity. 
  • 437
  • 09 Mar 2023
Topic Review
Periodontitis in Pregnant Women
Periodontitis develops in 11% of pregnant women, and it is independently linked to severe complications during pregnancy such as preterm birth, low birth weight, and gestational diabetes. Periodontal disease appears to be associated with adverse events in pregnancy due to the transport of biofilm bacteria into the bloodstream and into placental tissue; what would cause adverse events is the body’s immune response to infection.
  • 250
  • 29 May 2023
Topic Review
Periodontitis Classification, Clinical Features and Diagnosis
Periodontitis is a clinical condition where there is chronic inflammation of the periodontium, resulting in the loss of the periodontal ligament and damage to the surrounding alveolar bone. Various microorganisms have been linked to periodontitis. Chronic inflammation is responsible for various complications which are seen in periodontitis cases. For better treatment and diagnosis, it is important to understand the association of periodontitis with other systemic diseases.
  • 495
  • 31 Oct 2022
Topic Review
Periodontitis
Periodontitis is characterized by a complex inflammatory response triggered by the presence of a dental biofilm. This bacterial biofilm is able to elicit a dysbiosis in the subgingival microbiome leading to the destruction of the periodontal supporting tissues and eventually tooth loss.
  • 1.0K
  • 05 Apr 2023
Topic Review Peer Reviewed
Periodontal Regeneration
Periodontal regeneration is a technique that aims to regenerate the damaged tissue around periodontally compromised teeth. The regenerative process aims to use scaffolds, cells, and growth factors to enhance biological activity. 
  • 1.5K
  • 13 Apr 2022
Topic Review
Periodontal Diseases
Periodontal diseases, in the light of the new classification, have been divided into three general categories: gum disease, periodontitis, and other conditions affecting the periodontium.
  • 620
  • 14 Apr 2021
Topic Review
Periodontal Bifunctional Biomaterials
Periodontitis is a chronic infectious disease that destroys periodontal supportive tissues and eventually causes tooth loss. It is attributed to microbial and immune factors. The goal of periodontal therapy is to achieve complete alveolar bone regeneration while keeping inflammation well-controlled. To reach this goal, many single or composite biomaterials have been developed that can produce any two of the antibacterial, anti-inflammatory, and periodontal tissue regeneration effects, such as antibacterial and bone regeneration effects. They are called bifunctional biomaterials.
  • 601
  • 14 Dec 2021
Topic Review
Peri-Implantitis Regenerative Therapy
Peri-implant diseases are inflammatory conditions affecting the soft and hard tissues around dental implants. This review will focus on the regenerative treatment of peri-implant osseous defects in order to provide some evidence that can aid clinicians in the approach to peri-implant disease treatment. 
  • 593
  • 02 Sep 2021
Topic Review
Peri-Implant Diseases
Dental implant-supported prostheses are a well-established rehabilitation treatment for partially or completely edentulous patients that restore function and esthetics while having long-term survival rates. The tissues surrounding osseointegrated dental implants are referred to as peri-implant tissues, consisting of soft and hard tissue parts. The soft tissue part forms following the placement of implant/abutment during the wound healing and is known as “peri-implant mucosa,” while the hard tissue part makes contact with the implant surface to ensure implant stability.
  • 364
  • 25 May 2023
Topic Review
Peri-Implant Disease
Despite the high survival rate and success of dental implants, it has long been known that osseointegrated implants may suffer from biological complications, collectively referred to as peri-implant disease (PID).
  • 486
  • 09 Aug 2021
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