Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Cochliobolus, Bipolaris, and Curvularia Species
Cochliobolus, Bipolaris, and Curvularia genera contain various devastating plant pathogens that cause severe crop losses worldwide. The species belonging to these genera also perform a variety of diverse functions, including the remediation of environmental contaminations, beneficial phytohormone production, and maintaining their lifestyle as epiphytes, endophytes, and saprophytes. Research has revealed that despite their pathogenic nature, these fungi also play an intriguing role in agriculture. They act as phosphate solubilizers and produce phytohormones, such as indole acetic acid (IAA) and gibberellic acid (GAs), to accelerate the growth of various plants. Some species have also been reported to play a significant role in plant growth promotion during abiotic stresses, such as salinity stress, drought stress, heat stress, and heavy metal stress, as well as act as a biocontrol agent and a potential mycoherbicide. Similarly, these species have been reported in numerous industrial applications to produce different types of secondary metabolites and biotechnological products and possess a variety of biological properties, such as antibacterial, antileishmanial, cytotoxic, phytotoxic, and antioxidant activities.
  • 1.5K
  • 06 Mar 2023
Topic Review
Artificial Intelligence in Pain Detection
Pain is a complex and subjective experience, and traditional methods of pain assessment can be limited by factors such as self-report bias and observer variability. AI-based voice analysis can be an effective tool for pain detection in adult patients with various types of pain, including chronic and acute pain. 
  • 1.5K
  • 25 Apr 2023
Topic Review
Corrosion Stiction in Automotive Braking Systems
The rotor–brake pad assembly for application in automotive braking systems is a complex multimaterial system subjected to several aggressive environments, including rain, snow, and chlorides during winter driving. Corrosion issues involving the rotor–brake pad assembly, in particular for cast-iron rotors, can negatively affect the performance, safety, and reliability of the braking system. Under highly oxidative conditions, electrochemical processes occurring at the gray cast-iron rotor surface can generate corrosion products (iron oxides) that can penetrate the brake pad material through the intrinsic porosity of the friction material employed for the production of the brake pad. The corrosion of gray cast iron discs can lead to a strong adhesion of the brake pad at the pad/disc interface that can impair the reliability and performance of the braking system.
  • 1.5K
  • 30 May 2023
Topic Review
Sustainable Consumption and Circular Economy
Sustainable consumption is a key concept in society and the environment due to its direct relationship with sustainable development; its importance lies in the decoupling of consumption and economic growth with environmental damage and its involvement with various behavioral disciplines and ecological concepts. 
  • 1.5K
  • 01 Jun 2023
Topic Review
Plastic Pollution
Plastic is a word that initially meant “material that can be easily shaped, formed, molded by providing heat and pressure”. It only recently became a name for a category of materials called synthetic polymers. The polymer means “of many parts” and is a long chain of repeating smaller or larger molecules (monomers) bonded in subunits. Generally, natural polymers and synthetic polymers are used for making plastics. Synthetic polymers differ from natural polymers (such as silk, cellulose, muscle fiber, rubber, hair, and DNA). They are manufactured using raw materials such as oil, coal, and natural gas. There are two other types of plastics that do not fall into the above category of materials (natural or synthetic) and are known as biodegradable plastics and bioplastic materials. Biodegradable plastic is made from petroleum- or biomass-based resources. Bioplastic products are manufactured using biomass-based materials only. Both plastic materials are substitutes for synthetic plastic. 
  • 1.5K
  • 11 Mar 2024
Topic Review
Pathogenesis and Diagnosis of Immature Teratoma
An immature teratoma is a germinal malignant tumor that is composed of three germ cell layers (the ectoderm, endoderm, and mesoderm), and it is histologically characterized by immature tissue, most frequently, neuroepithelial tissue. The most frequently affected individuals are adolescents and young adults in their reproductive age.
  • 1.5K
  • 26 Apr 2023
Topic Review
Techniques for Editing Phage Genome
Bacteriophages, abbreviated as “phages”, have been developed as emerging nanoprobes for the detection of a wide variety of biological species, such as biomarker molecules and pathogens. Nanosized phages can display a certain length of exogenous peptides of arbitrary sequence or single-chain variable fragments (scFv) of antibodies that specifically bind to the targets of interest, such as animal cells, bacteria, viruses, and protein molecules. Metal nanoparticles generally have unique plasmon resonance effects. Metal nanoparticles such as gold, silver, and magnetism are widely used in the field of visual detection. A phage can be assembled with metal nanoparticles to form an organic–inorganic hybrid probe due to its nanometer-scale size and excellent modifiability. Due to the unique plasmon resonance effect of this composite probe, this technology can be used to visually detect objects of interest under a dark-field microscope.
  • 1.5K
  • 28 Feb 2022
Topic Review
C/EBPs
CCAAT-enhancer-binding proteins (C/EBPs) is a family of six structurally homologous transcription factors that promote the expression of genes involved in different cellular responses, such as proliferation, growth, and differentiation. These transcription factors control the differentiation of several cell types, and have key roles in regulating cellular proliferation, through interaction with cell cycle proteins. The molecular structure of C/EBPs and their ability to interact with a multitude of factors determine their complex functions in different cells. In fact, C/EBPs can be activated or inhibited by a variety of intracellular or extracellular signals. In addition, post-translational modifications and interaction with other proteins can regulate their expression and activity in a complex manner. C/EBPs can activate or repress several classes of genes implicated in cell differentiation, metabolism, inflammation, and immune response. Moreover, C/EBPs play an important role in cancer progression and metastasis, showing both pro-oncogenic and onco-suppressor functions. Interestingly, the same isotype of C/EBP can exhibit both of these opposite functions. This “Janus” role of C/EBPs in cancer could depend on their particular position at the crossroads between proliferation and differentiation. Specific conditions such as cell type, microenvironment, type of heterodimerization, or interaction with different regulatory proteins can tip the balance towards pro- or anti-oncogenic action.
  • 1.5K
  • 13 Sep 2021
Topic Review
Merkel Cell Polyomavirus
Merkel cell polyomavirus (MCV) is the only known human oncogenic virus in the polyomaviridae family and the etiological agent of most Merkel cell carcinomas (MCC). MCC is an aggressive and highly metastatic skin cancer with a propensity for recurrence and poor prognosis. Large tumor antigen (LT), is an essential oncoprotein for MCV transcription, viral replication, and cancer cell proliferation. MCV LT is a short-lived protein that encodes a unique domain: MCV LT unique regions (MURs). These domains consist of phosphorylation sites that interact with multiple E3 ligases, thus limiting LT expression and consequently, viral replication. In this study, we show that MURs are necessary for regulating LT stability via multiple E3 ligase interactions, resulting in cell growth arrest. While expression of wild-type MCV LT induced a decrease in cellular proliferation, deletion of the MUR domains resulted in increased LT stability and cell proliferation. Conversely, addition of MURs to SV40 LT propagated E3 ligase interactions, which in turn, reduced SV40 LT stability and decreased cell growth activity. Our results demonstrate that compared to other human polyomaviruses (HPyVs), MCV LT has evolved to acquire the MUR domains that are essential for MCV LT autoregulation, potentially leading to viral latency and MCC.
  • 1.5K
  • 09 Oct 2020
Topic Review
Cyclic Vomiting Syndrome
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age.
  • 1.5K
  • 24 Dec 2020
Topic Review
COL1A1 Gene
collagen type I alpha 1 chain
  • 1.5K
  • 24 Dec 2020
Topic Review
Zn(II) Hydrazone Complexes
Compound Name: (E)-N,N,N-trimethyl-2-oxo-2-(2-(1-(thiazol-2-yl)ethylidene)hydrazinyl)ethan-1-aminium di(thiocyanato-κN) zink(II) dihydrate.
  • 1.5K
  • 29 Dec 2020
Topic Review
The Microbiome and Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignant tumors due to the absence of biomarkers for early-stage detection and poor response to therapy.
  • 1.5K
  • 19 Jan 2021
Topic Review
Anterior-Segment Optical-Coherence Tomography
Anterior-segment optical-coherence tomography (AS-OCT) is used to assess the iridocorneal angle and its alterations. The introduction of AS-OCT has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly.
  • 1.5K
  • 14 Feb 2021
Topic Review
Essential Oils for Weed Control
In all farming systems, weeds are the most expensive pest to manage, accounting for 30% of potential losses. In organic farming, the problem may be further amplified by restrictions on herbicides, thus making weeds the main problem faced by organic farmers in the field. In this sense, much research is focusing on the allelopathic potential of plants as an ecological weed control tool. Many plant species can release allelopathic compounds with high phytotoxicity that can be used in weed control. Species belonging to the Lamiaceae family have been studied widely for this purpose, and their essential oils (EOs) appear to be promising bioherbicides. However, there are still many challenges for their development.
  • 1.5K
  • 27 Apr 2021
Topic Review
Magnetic Polymers for Microfluidic Sorting
Magnetophoresis offers many advantages for manipulating magnetic targets in microsystems. The integration of micro-flux concentrators and micro-magnets allows achieving large field gradients and therefore large reachable magnetic forces. However, the associated fabrication techniques are often complex and costly, and besides, they put specific constraints on the geometries. Magnetic composite polymers provide a promising alternative in terms of simplicity and fabrication costs, and they open new perspectives for the microstructuring, design, and integration of magnetic functions.
  • 1.5K
  • 30 Jul 2021
Topic Review
Determination of Psychoactive Drugs in Air
Understanding of the levels of psychoactive drugs in air is important for assessing both occupational and environmental exposure. Intelligence on the usage and manufacture of illegal drugs can also be gained. Environmental analysis and determination of air quality has recently expanded from its traditional focus to new pollutant categories that include illicit and psychoactive drugs. 
  • 1.5K
  • 22 Feb 2022
Topic Review
Fibroblast Growth Factor 23 and Osteoporosis
Osteoporosis is a chronic debilitating disease caused by imbalanced bone remodeling processes that impair the structural integrity of bone. Over the last ten years, the association between fibroblast growth factor 23 (FGF23) and osteoporosis has been studied in both pre-clinical and clinical investigations. FGF23 is a bone-derived endocrine factor that regulates mineral homeostasis via the fibroblast growth factor receptors (FGFRs)/αKlotho complex. These receptors are expressed in kidney and the parathyroid gland. Preclinical studies have supported the link between the local actions of FGF23 on the bone remodeling processes. In addition, clinical evidence regarding the effects of FGF23 on bone mass and fragility fractures suggest potential diagnostic and prognostic applications of FGF23 in clinical contexts, particularly in elderly and patients with chronic kidney disease. However, inconsistent findings exist and there are areas of uncertainty requiring exploration.
  • 1.5K
  • 16 Mar 2022
Topic Review
Acute Fatigue and Cognitive Performance in Team Sports
Fatigue caused by exercise or mentally demanding tasks can lead to an alteration in the cognitive functioning of athletes. I is important to investigate whether and to what extent fatigue influences athletes cognitive performance in sports with high cognitive demands. Prolonged exercise causes a decline in the decision-making, attention, and perception abilities of players. Accuracy of sport-specific tasks with cognitive components included rather deteriorated after both exercise and mental fatigue inducement. However, alteration of players cognitive performance depends on the intensity and duration of fatigue-inducing tasks. 
  • 1.5K
  • 24 Mar 2022
Topic Review
Blockchain for Future Wireless Networks
The emerging need for high data rate, low latency, and high network capacity encourages wireless networks (WNs) to build intelligent and dynamic services, such as intelligent transportation systems, smart homes, smart cities, industrial automation, etc. The WN is impeded by several security threats, such as data manipulation, denial-of-service, injection, man-in-the-middle, session hijacking attacks, etc., that deteriorate the security performance of the aforementioned WN-based intelligent services. Toward this goal, various security solutions, such as cryptography, artificial intelligence (AI), access control, authentication, etc., are proposed by the scientific community around the world.
  • 1.5K
  • 08 Jul 2022
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback