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Topic Review
Electric Vehicle Batteries
In electric and hybrid vehicles Life Cycle Assessments (LCAs), batteries play a central role and are in the spotlight of scientific community and public opinion. Automotive batteries constitute, together with the powertrain, the main differences between electric vehicles and internal combustion engine vehicles. For this reason, many decision makers and researchers wondered whether energy and environmental impacts from batteries production, can exceed the benefits generated during the vehicle’s use phase. In this framework, the purpose of the present literature review is to understand how large and variable the main impacts are due to automotive batteries’ life cycle, with particular attention to climate change impacts, and to support researchers with some methodological suggestions in the field of automotive batteries’ LCA. The results show that there is high variability in environmental impact assessment; CO2eq emissions per kWh of battery capacity range from 50 to 313 g CO2eq/kWh. Nevertheless, either using the lower or upper bounds of this range, electric vehicles result less carbon-intensive in their life cycle than corresponding diesel or petrol vehicles.
  • 1.6K
  • 27 Oct 2020
Topic Review
Oxidative Stress in Periodontal Disease
Periodontal disease dominates as the most common inflammatory disease in the oral cavity. There is growing evidence on the involvement of oxidative stress, which is simply described as the imbalance between oxidants and antioxidants in favor of the former, in the initiation and progression of periodontal disease. Redox mechanistic insights that underlie immuno-inflammatory pathway may thus advance our understanding about periodontal pathogenesis, serving as the background for the development of efficient strategies for periodontal disease prevention and treatment.
  • 1.6K
  • 15 Jan 2021
Topic Review
Radiomics
Radiomics is a new frontier of medicine based on the extraction of quantitative features (named radiomic features) from radiological images that cannot be seen by radiologist’s naked eye and on the use of these data for the creation of clinical decision support systems.
  • 1.6K
  • 18 Mar 2021
Topic Review
Antioxidants and Carbon-Based Electrodes
Antioxidants are compounds that prevent or delay the oxidation process, acting at a much smaller concentration, in comparison to that of the preserved substrate. Primary antioxidants act as scavenging or chain breaking antioxidants, delaying initiation or interrupting propagation step. Secondary antioxidants quench singlet oxygen, decompose peroxides in non-radical species, chelate prooxidative metal ions, inhibit oxidative enzymes. Based on antioxidants’ reactivity, four lines of defense have been described: Preventative antioxidants, radical scavengers, repair antioxidants, and antioxidants relying on adaptation mechanisms. Carbon-based electrodes are largely employed in electroanalysis given their special features, that encompass large surface area, high electroconductivity, chemical stability, nanostructuring possibilities, facility of manufacturing at low cost, and easiness of surface modification. Largely employed methods encompass voltammetry, amperometry, biamperometry and potentiometry. Determination of key endogenous and exogenous individual antioxidants, as well as of antioxidant activity and its main contributors relied on unmodified or modified carbon electrodes, whose analytical parameters are detailed. Recent advances based on modifications with carbon-nanotubes or the use of hybrid nanocomposite materials are described. Large effective surface area, increased mass transport, electrocatalytical effects, improved sensitivity, and low detection limits in the nanomolar range were reported, with applications validated in complex media such as foodstuffs and biological samples.
  • 1.6K
  • 12 Apr 2021
Topic Review
CRM for Additive Manufacturing
The term “critical raw materials” (CRMs) refers to various metals and nonmetals that are crucial to Europe’s economic progress. Modern technologies enabling effective use and recyclability of CRMs are in critical demand for the EU industries. The use of CRMs, especially in the fields of biomedicine, aerospace, electric vehicles, and energy applications, is almost irreplaceable. Additive manufacturing (also referred to as 3D printing) is one of the key enabling technologies in the field of manufacturing which underpins the Fourth Industrial Revolution. 3D printing not only suppresses waste but also provides an efficient buy-to-fly ratio and possesses the potential to entirely change supply and distribution chains, significantly reducing costs and revolutionizing all logistics. This review provides comprehensive new insights into CRM-containing materials processed by modern additive manufacturing techniques and outlines the potential for increasing the efficiency of CRMs utilization and reducing the dependence on CRMs through wider industrial incorporation of AM and specifics of powder bed AM methods making them prime candidates for such developments.
  • 1.6K
  • 05 May 2021
Topic Review
Biogenic Amine Production by LAB
Lactic acid bacteria (LAB) are considered important biogenic amine (BA) producers in fermented foods. These compounds derive from amino acid decarboxylation through microbial activities and can cause toxic effects on humans, with symptoms (headache, heart palpitations, vomiting, diarrhea) depending also on individual sensitivity. Many studies have focused on the aminobiogenic potential of LAB associated with fermented foods, taking into consideration the conditions affecting BA accumulation and enzymes/genes involved in the biosynthetic mechanisms.
  • 1.6K
  • 27 May 2021
Topic Review
Chemical Rings
The epoxidized group, also known as the oxirane group, can be considered as one of the most crucial rings in chemistry. Due to the high ring strain and the polarization of the C–O bond in this three-membered ring, several reactions can be carried out. One can see such a functional group as a crucial intermediate in fuels, polymers, materials, fine chemistry, etc. 
  • 1.6K
  • 30 Aug 2021
Topic Review
SIRT7
Sirtuins are key players for maintaining cellular homeostasis and are often deregulated in different human diseases. SIRT7 is the only member of mammalian sirtuins that principally resides in the nucleolus, a nuclear compartment involved in ribosomal biogenesis, senescence, and cellular stress responses. The ablation of SIRT7 induces global genomic instability, premature ageing, metabolic dysfunctions, and reduced stress tolerance, highlighting its critical role in counteracting ageing-associated processes.
  • 1.6K
  • 15 Oct 2021
Topic Review
MERTK and AXL in NSCLC
MERTK and AXL are members of the TAM family of receptor tyrosine kinases and are abnormally expressed in 69% and 93% of non-small cell lung cancers (NSCLCs), respectively. Expression of MERTK and/or AXL provides a survival advantage for NSCLC cells and correlates with lymph node metastasis, drug resistance, and disease progression in patients with NSCLC. The TAM receptors on host tumor infiltrating cells also play important roles in the immunosuppressive tumor microenvironment. Thus, MERTK and AXL are attractive biologic targets for NSCLC treatment. 
  • 1.6K
  • 29 Mar 2022
Topic Review
Orientation of the Kofun Tombs
The Kofun period of the history of Japan—between the 3rd and the 7th century AD—bears its name from the construction of huge, earth mound tombs called Kofun. Among them, the largest have a keyhole shape and are attributed to the first, semi-legendary emperors. 
  • 1.6K
  • 17 Feb 2022
Topic Review
Stability of Cu-Based Catalysts for Methanol Reforming
The stability of copper-based catalysts is an important property that affects the catalytic efficiency, which determines the service life of the catalytic base in the methanol steam reforming (MSR) reaction, and plays an important role in the sustainable production of hydrogen.
  • 1.6K
  • 21 Jul 2022
Topic Review
The Association between Biofilm Formation and Antimicrobial Resistance
Biofilm has garnered a lot of interest due to concerns in various sectors such as public health, medicine, and the pharmaceutical industry. Biofilm-producing bacteria show a remarkable drug resistance capability, leading to an increase in morbidity and mortality.
  • 1.6K
  • 22 Jul 2022
Topic Review
Mood Congruence
Mood congruence is a type of recall biased mood congruent memory, not to be mistaken with mood-dependent memory, where an individual's current mood or affective state determines the affective association of the memories that are recalled. In psychology, memories are said to be mood-congruent if they are consistent with a patient's mood or mental disorder. Mental disorders regarding mood congruence are exampled as clinical depression or bi-polar disorder.
  • 1.6K
  • 10 Oct 2022
Topic Review
Forensic Identification
Forensic identification is the application of forensic science, or "forensics", and technology to identify specific objects from the trace evidence they leave, often at a crime scene or the scene of an accident. Forensic means "for the courts".
  • 1.6K
  • 25 Oct 2022
Topic Review
ADM Energy
The ADM formalism (named for its authors Richard Arnowitt, Stanley Deser and Charles W. Misner) is a Hamiltonian formulation of general relativity that plays an important role in canonical quantum gravity and numerical relativity. It was first published in 1959. The comprehensive review of the formalism that the authors published in 1962 has been reprinted in the journal General Relativity and Gravitation, while the original papers can be found in the archives of Physical Review.
  • 1.6K
  • 08 Nov 2022
Topic Review
Developments in FRET- and BRET-Based Biosensors
Resonance energy transfer technologies have achieved great success in the field of analysis. Particularly, fluorescence resonance energy transfer (FRET) and bioluminescence resonance energy transfer (BRET) provide strategies to design tools for sensing molecules and monitoring biological processes, which promote the development of biosensors.
  • 1.6K
  • 06 Jan 2023
Topic Review
Sandstone-Type Uranium Deposits in Hydrocarbon-Bearing Basins
As a valuable mineral resource, uranium is extensively utilized in nuclear power generation, radiation therapy, isotope labeling, and tracing. In order to achieve energy structure diversification, reduce dependence on traditional fossil fuels, and promote the sustainable development of energy production and consumption, research on the metallogenic mechanisms and related development technologies of uranium resources has been one of the focuses of China’s energy development. Sandstone-type uranium deposits make up approximately 43% of all deposits in China, making them the most prevalent form of uranium deposit there.
  • 1.6K
  • 28 Jun 2023
Topic Review
Formation and Partitioning Theories of the Mixed Micelle
When two or more surfactants are mixed, the critical micelle concentration and solubilization capability are changed, and a careful selection of the combination promotes the micelle formation and enhances the solubilizing capability. Thus, understanding the mechanism behind the phenomena is essential for controlling the physical properties of the mixed micelle. The interaction parameters β and B that describe the formation of mixed micelles and their partitioning of solutes, respectively, were proposed by Treiner four decades ago. 
  • 1.6K
  • 26 Feb 2024
Topic Review
Motor Imagery
Scholars have recently used “motor imagery” (MI) to refer to the imagination of moving particular body parts. Among the frameworks trying to explain the essence of motor imagery, there are two primary ones—motor simulation and motor emulation theory.
  • 1.6K
  • 27 Apr 2022
Topic Review
Principal Postulates of Centrosomal Biology
The centrosome, which consists of two centrioles surrounded by pericentriolar material, is a unique structure that has retained its main features in organisms of various taxonomic groups from unicellular algae to mammals over one billion years of evolution. In addition to the most noticeable function of organizing the microtubule system in mitosis and interphase, the centrosome performs many other cell functions. In particular, centrioles are the basis for the formation of sensory primary cilia and motile cilia and flagella. Another principal function of centrosomes is the concentration in one place of regulatory proteins responsible for the cell's progression along the cell cycle. Despite the existing exceptions, the functioning of the centrosome is subject to general principles.
  • 1.6K
  • 15 Oct 2020
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