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Topic Review
Carbon Dots Composites
Among carbon-based nanomaterials, carbon dots (CDs) have received a surge of interest in recent years due to their attractive features such as tunable photoluminescence, cost effectiveness, nontoxic renewable resources, quick and direct reactions, chemical and superior water solubility, good cell-membrane permeability, and simple operation. CDs and their composites have a large potential for sensing contaminants present in physical systems such as water resources as well as biological systems. Tuning the properties of CDs is a very important subject.
  • 1.6K
  • 17 Oct 2022
Topic Review
Ringed Seals and Climate Change
Ringed seals are the smallest and most abundant member of the seal family that live in the Arctic and Sub-Arctic regions. The average life span of a ringed seal is 40 years, with a diet based mainly on Arctic cod and planktonic crustaceans. Typically about 5 feet (1.5 m) long, the ringed seal is known to be solitary with their main predator being polar bears. Recently, however, the biggest predator to ringed seals has been the changing temperature in the Arctic and the detrimental changes to sea ice that follow. With declines in snowpack and sea ice due to warming ocean and atmospheric temperatures, survival has become tougher for ringed seals in the Arctic and Sub-Arctic regions. Yet ringed seals are also potentially projected to thrive due to warming, considering the early extinction of their predators. Climate change is sure to change the fate of all ringed seals in the coming years for better or worse.
  • 1.6K
  • 20 Oct 2022
Topic Review
Electrochemical Biosensors for Pathogen Detection
Electrochemical biosensors are a family of biosensors that use an electrochemical transducer to perform their functions. In recent decades, many electrochemical biosensors have been created for pathogen detection. These biosensors for detecting infections have been comprehensively studied in terms of transduction elements, biorecognition components, and electrochemical methods. The integration of transducers and electrode changes in biosensor design is a major discussion topic. Pathogen detection methods can be categorized by sample preparation and secondary binding processes. Diagnostics in medicine, environmental monitoring, and biothreat detection can benefit from electrochemical biosensors to ensure food and water safety.
  • 1.6K
  • 02 Nov 2022
Topic Review
Marketization
Marketization or marketisation is a restructuring process that enables state enterprises to operate as market-oriented firms by changing the legal environment in which they operate. This is achieved through reduction of state subsidies, organizational restructuring of management (corporatization), decentralization and in some cases partial privatization. These steps, it is argued, will lead to the creation of a functioning market system by converting the previous state enterprises to operate under market pressures as state-owned commercial enterprises.
  • 1.6K
  • 04 Nov 2022
Topic Review
Skeleton-Based Sign Language Recognition
Skeleton-based sign language recognition (SLR) systems that mainly use specific skeleton points instead of the pixels of images and/or sensors. The main advantage of skeleton-based SLR systems is that they can increase the attention paid to signs and have strong adaptability to complicated backgrounds and dynamic circumstances. The use of hand skeleton information alone is sometimes insufficient to correctly represent the exact meaning of a sign due to a lack of emotion and bodily expression.
  • 1.6K
  • 04 Jul 2023
Topic Review
Benchmarking Message Queues
Message queues are a way for different software components or applications to communicate with each other asynchronously by passing messages through a shared buffer. This allows a sender to send a message without needing to wait for an immediate response from the receiver, which can help to improve the system’s performance, reduce latency, and allow components to operate independently. The performance of four popular message queues: Redis, ActiveMQ Artemis, RabbitMQ, and Apache Kafka was compared.
  • 1.6K
  • 24 Jul 2023
Topic Review
Macrophage Polarization States
The M1/M2 macrophage paradigm plays a key role in tumor progression. M1 macrophages are historically regarded as anti-tumor, while M2-polarized macrophages, commonly deemed tumor-associated macrophages (TAMs), are contributors to many pro-tumorigenic outcomes in cancer through angiogenic and lymphangiogenic regulation, immune suppression, hypoxia induction, tumor cell proliferation, and metastasis.
  • 1.6K
  • 21 Jul 2021
Topic Review
Plasmids Mediating Quinolone Resistance
Plasmid-mediated quinolone resistance (PMQR) remains one of the main mechanisms of bacterial quinolone resistance and plays an important role in the transmission of antibiotic resistance genes (ARGs). The two novel plasmids, p3M-2A and p3M-2B, which mediate quinolone resistance in Proteus vulgaris strain 3M (P3M) were identified. Of these, only p3M-2B appeared to be a qnrD-carrying plasmid. Both p3M-2A and p3M-2B could be transferred into Escherichia coli, and the latter caused a twofold change in ciprofloxacin resistance, according to the measured minimum inhibitory concentration (MIC). Plasmid curing/complementation and qRT-PCR results showed that p3M-2A can directly regulate the expression of qnrD in p3M-2B under treatment with ciprofloxacin, in which process, ORF1 was found to play an important role. Sequence alignments and phylogenetic analysis revealed the evolutionary relationships of all reported qnrD-carrying plasmids and showed that ORF1–4 in p3M-2B is the most conserved backbone for the normal function of qnrD-carrying plasmids. The identified direct repeats (DR) suggested that, from an evolutionary perspective, p3M-2B may have originated from the 2683-bp qnrD-carrying plasmid and may increase the possibility of plasmid recombination and then of qnrD transfer. To the best of our knowledge, this is the first identification of a novel qnrD-carrying plasmid isolated from a P. vulgaris strain of shrimp origin and a plasmid that plays a regulatory role in qnrD expression. This study also sheds new light on plasmid evolution and on the mechanism of horizontal transfer of ARGs encoded by plasmids.
  • 1.6K
  • 27 Oct 2020
Topic Review
Capsicum annuum L.
Capsicum annuum L. is a significant horticulture crop known for its pungent varieties and used as a spice. The pungent character in the plant, known as capsaicinoid, has been discovered to have various health benefits. However, its production has been affected due to various exogenous stresses, including diseases caused by a soil-borne pathogen, Pythium spp. Predominantly affecting the Capsicum plant in younger stages and causing damping-off, this pathogen can incite root rot in later plant growth stages. Due to the involvement of multiple Pythium spp. and their capability to disperse through various routes, their detection and diagnosis have become crucial. However, the quest for a point-of-care technology is still far from over. The use of an integrated approach with cultural and biological techniques for the management of Pythium spp. can be the best and most sustainable alternative to the traditionally used and hazardous chemical approach. The lack of race-specific resistance genes against Pythium spp. can be compensated with the candidate quantitative trait loci (QTL) genes in C. annuum L.
  • 1.6K
  • 28 Apr 2021
Topic Review
Electronic Health Records
The increasing use of electronic health record (EHR)-based systems has led to the generation of clinical data at an unprecedented rate, which produces an untapped resource for healthcare experts to improve the quality of care. Despite the growing demand for adopting EHRs, the large amount of clinical data has made some analytical and cognitive processes more challenging. The emergence of a type of computational system called visual analytics has the potential to handle information overload challenges in EHRs by integrating analytics techniques with interactive visualizations. 
  • 1.6K
  • 04 Jun 2021
Topic Review
Packaging Type and Wine
This is a mini-review that looks at how different types of packaging can impact the sensory characteristics of wine. This mini-review compared  glass bottles, polyethylene terephthalate (PET), Bag-in-box (BIB), aluminum cans, and Terta Pak. Some of the most common packaging types used by the wine industry at the moment. This mini-review looked at the history of wine packaging, the impact packaging type has on the flavor profile of wine, and consumers attitudes towards the different types of packaging. While glass is still the dominate packaging material within the wine industry and by consumer demand however, economic and environmental concerns are driving the industry and consumers to investigate and adopt alternative packaging materials.
  • 1.6K
  • 25 Jun 2021
Topic Review
Occurrence of Triclosan in the Water Environment
Triclosan (TCS), a kind of pharmaceuticals and personal care products (PPCPs), is widely used and has had a large production over years. It is an emerging pollutant in the water environment that has attracted global attention due to its toxic effects on organisms and aquatic ecosystems, and its concentrations in the water environment are expected to increase since the COVID-19 pandemic outbreak.
  • 1.6K
  • 09 Sep 2022
Topic Review
Major Challenges for Seafood Packaging
Seafood is a highly economical product worldwide. Primary modes of deterioration include autolysis, oxidation of protein and lipids, formation of biogenic amines and melanosis, and microbial deterioration. These post-harvest losses can be properly handled if the appropriate packaging technology has been applied. Therefore, it is necessary for packaging deterioration relevance to be clearly understood. 
  • 1.6K
  • 28 Sep 2022
Topic Review
Local Search (Internet)
Local search is the use of specialized Internet search engines that allow users to submit geographically constrained searches against a structured database of local business listings. Typical local search queries include not only information about "what" the site visitor is searching for (such as keywords, a business category, or the name of a consumer product) but also "where" information, such as a street address, city name, postal code, or geographic coordinates like latitude and longitude. Examples of local searches include "Hong Kong hotels", "Manhattan restaurants", and "Dublin car rental". Local searches exhibit explicit or implicit local intent. A search that includes a location modifier, such as "Bellevue, WA" or "14th arrondissement", is an explicit local search. A search that references a product or service that is typically consumed locally, such as "restaurant" or "nail salon", is an implicit local search. Local searches on Google Search typically return organic results prefaced with a 'local 3-pack', a list of three local results. More local results can be obtained by clicking on “more places” under the 3-pack. The list of results one obtains is also called the Local Finder. Search engines and directories are primarily supported by advertising from businesses that wish to be prominently featured when users search for specific products and services in specific locations. Google for instance, has developed local inventory ads and features ads in the local pack. Local search advertising can be highly effective because it allows ads to be targeted very precisely to the search terms and location provided by the user.
  • 1.6K
  • 29 Sep 2022
Topic Review
40M Turán
The Turán was a Hungarian medium tank of World War II. It was inspired and used the technology-based solutions found on the design of the Czechoslovak Škoda T-21 medium tank prototype, it was produced in two main variants: the 40M Turán (or Turán I) with a 40 mm gun and the 41M Turán (or Turán II) with a 75 mm gun. A total of 424 were made. A prototype variant, the 43M Turán (or Turán III) was also turned out but did not go into production. Prototypes were manufactured, but work on the project stopped in 1944 when the mass-producing terminated in the country.
  • 1.6K
  • 01 Nov 2022
Topic Review
Lewy Body Dementia
Lewy body dementia (LBD, or Lewy body disorder) is an umbrella term that encompasses two similar dementias, both of which are characterized by abnormal deposits of the protein alpha-synuclein in the brain: The two conditions have similar features, may have similar causes, and can be viewed as part of a spectrum. As of 2014, they were more often misdiagnosed than any other common dementia.
  • 1.6K
  • 01 Nov 2022
Topic Review
ATI Video Card Suffixes
ATI video cards can have one of multiple suffixes attached to their name indicating relative level of performance, the use of suffixes was abandoned with the release of Radeon HD 3000 series products, the last two digits of the model number was then used to indicate relative performance of the products, except for the "X2" suffix indicating dual-GPU solutions, such that the product has two GPUs on one PCB. Below is the listing of the suffixes used in previous generations of products, in order from least powerful (at the top) to the most powerful. (at the bottom) Not all suffixes will be found on a particular line of cards.
  • 1.6K
  • 18 Nov 2022
Topic Review
Comparison of Regular-Expression Engines
This is a comparison of regular-expression engines.
  • 1.6K
  • 24 Nov 2022
Topic Review
Thermal Conductivity Improvement of PCCs
To overcome the long-standing disadvantages of PCMs, for instance, small values of thermal conductivity, liquid leakage, separation of phase, and the problem of supercooling, advanced phase change composites (PCCs) manufactured by chemical modifications or the incorporation of functional additives are essential to overcome these disadvantages and promote the large-scale application of PCMs.
  • 1.6K
  • 29 Nov 2022
Topic Review
Dermo-Cosmetic Benefits of Marine Macroalgae-Derived Phenolic Compounds
Marine macroalgae have an interesting profile of bioactive compounds and have gained tremendous attention in cosmeceuticals with negligible toxicity effects (cytotoxicity, reproductive toxicity, genotoxicity, mutagenicity, carcinogenicity, etc.) on humans and exhibit strong benefits for the skin. Among the diversified compounds, phenolic compounds are the group of phytochemicals found in high amounts with great structural diversity. Phlorotannin is the most studied polyphenol compound in brown algae, but besides there are some other phenolic compounds observed and studied in macroalgae such as terpenoids, bromophenols, mycosporine amino acids (MAAs), and flavonoids. These compounds are already characterized and studied for their full range of cosmeceutical benefits such as skin whitening, moisturizing, photoprotection, antiaging, antiwrinkle, anti-melanogenic, and antioxidant activities as well as in the treatment of pruritus (caused by acne, eczema, dermatitis, hives, psoriasis), photoaging, and skin pigmentation disorders (hypopigmentation due to the absence of melanocytes and hyperpigmentation caused by skin irritation or metabolic disorders). 
  • 1.6K
  • 05 Dec 2022
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