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Topic Review
Unmanned Aerial Systems in Hydrogeology
In less than two decades, UASs (unmanned aerial systems) have revolutionized the field of hydrology, bridging the gap between traditional satellite observations and ground-based measurements and allowing the limitations of manned aircraft to be overcome. With unparalleled spatial and temporal resolutions and product-tailoring possibilities, UAS are contributing to the acquisition of large volumes of data on water bodies, submerged parameters and their interactions in different hydrological contexts and in inaccessible or hazardous locations. 
  • 1.7K
  • 29 Apr 2021
Topic Review
Vitamin D in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic demyelinating disease of central nervous system and is caused by an aberrant immune response to myelin sheath. Disease-modifying medications, which mainly aim to suppress such aberrant immune response, have significantly improved MS treatment. However, the disease severity continues to worsen. In contrast, progressively more data suggest that 1,25-dihydroxyvitamin D or 1,25(OH)2D, i.e., the active vitamin D, suppresses the differentiation of potentially pathogenic T cells associated with MS, enhances the differentiation of regulatory T cells that suppress the pathogenic T cells, and promotes remyelination. These novel 1,25(OH)2D functions have encouraged investigators to develop vitamin D as a potential therapy for MS. However, because of the hypercalcemia that is associated with high 1,25(OH)2D concentrations, supplementation of native vitamin D has been a major focus in clinical trials for the treatment of MS, but such trials have produced mixed data. In this article, we will review current progress in the supplementation of different vitamin D forms for the treatment of experimental autoimmune encephalomyelitis (i.e., an MS animal model) as well as MS.
  • 1.7K
  • 28 Oct 2020
Topic Review
Nanoparticle–Graphene based Nanocomposites
Bacterial infections are a leading cause of death in both Europe and USA. The use of antibacterial nanomaterials is a very promising approach to combat the microorganisms due to their high specific surface area and intrinsic or chemically incorporated antibacterial action. Graphene, a two dimensional carbon nanomaterial with excellent mechanical, thermal, and electrical properties, and its derivatives, like graphene oxide (GO) and reduced graphene oxide (rGO), are very good candidates for controlling microbial infections. Nonetheless, the mechanisms of antimicrobial action, their cytotoxicity, and other issues continue imprecise. This review offers select examples on the leading advances in the development of antimicrobial nanocomposites incorporating inorganic nanoparticles and graphene or its derivatives, with the goal of providing a improved understanding of the antibacterial properties of graphene-based nanomaterials.
  • 1.7K
  • 02 Nov 2020
Topic Review
Platelets, Depression and its Co-Morbidities
Alongside their function in primary haemostasis and thrombo-inflammation, platelets are increasingly considered a bridge between mental, immunological and coagulation-related disorders. This review focuses on the link between platelets and the pathophysiology of major depressive disorder (MDD) and its most frequent comorbidities. Platelet- and neuron-shared proteins involved in MDD are functionally described. Platelet-related studies performed in the context of MDD, cardiovascular disease, and major neurodegenerative, neuropsychiatric and neurodevelopmental disorders are transversally presented from an epidemiological, genetic and functional point of view. To provide a complete scenario, we report the analysis of original data on the epidemiological link between platelets and depression symptoms suggesting moderating and interactive effects of sex on this association. Epidemiological and genetic studies discussed suggest that blood platelets might be relevant biomarkers of MDD prediction and occurrence also in the context of MDD comorbidities. Finally, this review has the ambition to formulate some directives and perspectives for future research on this topic.
  • 1.7K
  • 02 Dec 2020
Topic Review
Glycosylation of Cancer Extracellular Vesicles
Glycans are major constituents of extracellular vesicles (EVs). Alterations in the glycosylation pathway are a common feature of cancer cells, which gives rise to de novo or increased synthesis of particular glycans. Therefore, glycans and glycoproteins have been widely used in the clinic as both stratification and prognosis cancer biomarkers. Interestingly, several of the tumor-associated glycans have already been identified in cancer EVs, which constitutes valuable sources of cancer biomarkers. Furthermore, glycans have also shown to play a role in EV protein sorting, uptake and tropism. Altogether, the EV glycan signatures hold tremendous potential to be applied into the clinical setting for both biomarker discovery and as therapeutic delivery systems.
  • 1.7K
  • 25 Jan 2021
Topic Review
Cation-Chloride Cotransporters
Stroke is one of the major culprits responsible for morbidity and mortality worldwide, and the currently available pharmacological strategies to combat this global disease are scanty. Cation-chloride cotransporters (CCCs) are expressed in several tissues (including neurons) and extensively contribute to the maintenance of numerous physiological functions including chloride homeostasis.
  • 1.7K
  • 07 Feb 2021
Topic Review
Visibility Enhancement and Fog Detection
In mobile systems, fog, rain, snow, haze, and sun glare are natural phenomena that can be very dangerous for drivers. In addition to the visibility problem, the driver must face also the choice of speed while driving. The main effects of fog are a decrease in contrast and a fade of color. Rain and snow cause also high perturbation for the driver while glare caused by the sun or by other traffic participants can be very dangerous even for a short period. In the field of autonomous vehicles, visibility is of the utmost importance. To solve this problem, different researchers have approached and offered varied solutions and methods. It is useful to focus on what has been presented in the scientific literature over the past ten years relative to these concerns. 
  • 1.7K
  • 28 May 2021
Topic Review
Applications of Magnetic Hydrogels
Magnetic hydrogels (MHGs) are a special class of hydrogel that contain at least one magnetic component in their composition. Generally, MNPs are dispersed in a polymer gel matrix to form MHGs. These hydrogels are special because they are prone to show fluctuations in their physical properties in the presence of an externally applied magnetic field.
  • 1.7K
  • 08 Dec 2021
Topic Review
Ejabberd
ejabberd is an Extensible Messaging and Presence Protocol (XMPP) application server and an MQ Telemetry Transport (MQTT) broker, written mainly in the Erlang programming language. It can run under several Unix-like operating systems such as macOS, Linux, FreeBSD, NetBSD, OpenBSD and OpenSolaris. Additionally, ejabberd can run under Microsoft Windows. The name ejabberd stands for Erlang Jabber Daemon (Jabber being a former name for XMPP) and is written in lowercase only, as is common for daemon software. ejabberd is free software, distributed under the terms of the GNU GPL-2.0-or-later. (As of 2009), it is one of the most popular open source applications written in Erlang. XMPP: The Definitive Guide (O'Reilly Media, 2009) praised ejabberd for its scalability and clustering feature, at the same time pointing out that being written in Erlang is a potential acceptance issue for users and contributors. The software's creator, Alexey Shchepin was awarded the Erlang User of the Year award at the 2006 Erlang user conference. ejabberd has a number of notable deployments, IETF Groupchat Service, BBC Radio LiveText, Nokia's Ovi, KDE Talk and one in development at Facebook. (As of 2009) ejabberd is the most popular server among smaller XMPP-powered sites that register on xmpp.org. With the next major release after version 2 (previously called ejabberd 3), the versioning scheme was changed to reflect release dates as "Year.Month-Revision" (starting with 13.04-beta1). It was also announced that further development will be split into an "ejabberd Community Server" and an "ejabberd Commercial Edition [which] targets carriers, websites, service providers, large corporations, universities, game companies, that need high level of commitment from ProcessOne, stability and performance and a unique set of features to run their business successfully."
  • 1.7K
  • 01 Nov 2022
Topic Review
Methods for Intensifying Biogas Production from Waste
The topic of intensification of bioprocesses is widely discussed in agricultural countries and countries with a large amount of organic waste. Therefore, the study of bioprocess intensification methods can help increase qualitative and quantitative indicators of biogas yield by using a combination of intensification methods.
  • 1.7K
  • 02 Nov 2022
Topic Review
Pigeon Toe
Pigeon toe, also known as in-toeing, is a condition which causes the toes to point inward when walking. It is most common in infants and children under two years of age and, when not the result of simple muscle weakness, normally arises from underlying conditions, such as a twisted shin bone or an excessive anteversion (femoral head is more than 15° from the angle of torsion) resulting in the twisting of the thigh bone when the front part of a person's foot is turned in.
  • 1.7K
  • 21 Nov 2022
Topic Review
Pennisetum Purpureum
Pennisetum purpureum (updated name: Cenchrus purpureus Schumach) , also known as Napier grass, elephant grass or Uganda grass, is a species of perennial tropical grass native to the African grasslands. It has low water and nutrient requirements, and therefore can make use of otherwise uncultivated lands. Historically, this wild species has been used primarily for grazing; recently, however, it has been used as part of a push–pull agricultural pest management strategy. This technique involves the desired crop being planted alongside a 'push' plant, which repels pests, in combination with a 'pull' crop around the perimeter of the plot, which draw insects out of the plot. Napier grass has shown potential at attracting stemborer moths (a main cause of yield loss in Africa) away from maize and hence is the "pull" crop. This strategy is much more sustainable, serves more purposes and is more affordable for farmers than insecticide use. In addition to this, Napier grasses improve soil fertility, and protect arid land from soil erosion. It is also utilized for firebreaks, windbreaks, in paper pulp production and most recently to produce bio-oil, biogas and charcoal.
  • 1.7K
  • 22 Nov 2022
Topic Review
Tom-Tom Drum
A tom drum is a cylindrical drum with no snares, named from the Anglo-Indian and Sinhala language. It was added to the drum kit in the early part of the 20th century. Most toms range in size between 6 and 20 inches (15 and 51 cm) in diameter, though floor toms can go as large as 24 inches (61 cm). It is not to be confused with a tam-tam, a gong. The Tom is popular and used by players worldwide.
  • 1.7K
  • 28 Nov 2022
Biography
Waheed Arian
Waheed Arian (born 5 August 1983) is a British doctor and radiologist, born in Afghanistan, who founded a telemedicine charity called Arian Teleheal. The charity enables doctors in conflict zones and low resource countries to use their smartphones to receive advice from volunteer specialists in the UK, Canada, the US and other countries. Arian has won several international awards for his achieve
  • 1.7K
  • 12 Dec 2022
Topic Review
Synthesis of Metal Complexes of 2-Thiouracil and Derivatives
The thionamide antithyroid agents were discovered largely through observations carried out by various researchers in the 1940s that found that sulfhydryl-containing substances were goitrogenic in animals. Prof. Edwin B. Astwood started using these drugs to treat hyperthyroidism. The development background of these agents, the coordination possibility of 2-thiouracil and its derivatives are presented herein.
  • 1.7K
  • 12 Apr 2024
Topic Review
Anomaly Detection in Autonomous Robotic Missions
An anomaly in autonomous robotic missions (ARM) is a deviation from the expected behaviour, performance, or state of the robotic system and its environment, which may impact the mission’s objectives, safety, or efficiency; and this anomaly can be caused either by system faults or the change in the environmental dynamics of interaction. The nuanced understanding of anomaly categories facilitates a more strategic approach, ensuring that detection methods are more effective in addressing the specific nature of the anomaly.
  • 1.7K
  • 11 Mar 2024
Topic Review
The Interplay between Plants and Microbial Communities
Plant-microbe interactions are critical for ecosystem functioning and driving rhizosphere processes. To fully understand the communication pathways between plants and rhizosphere microbes, it is crucial to measure the numerous processes that occur in the plant and the rhizosphere. Plants can host a wide range of microbes, collectively known as the plant microbiome, in the rhizosphere (i.e., the region of soil in the vicinity of plant roots), endosphere (i.e., plant internal tissues), and phyllosphere (i.e., stem, leaves, or flowers). These microbiomes form long-lasting interactions with the host plant, leading to positive, neutral, or negative impacts on crop performance and microbe-mediated biogeochemical processes.
  • 1.7K
  • 08 Feb 2023
Topic Review
Cassia alata (Linnaeus) Roxburgh for Skin
Atopic dermatitis (AD) is an inflamed skin condition with relapsing pruritus and cutaneous physiological dysfunction. This skin disorder is widespread around the world and frequently affects infants, children and adults. Natural products with bioactive lead compounds are the source of natural medicines for complementary and alternative therapy in managing AD. Cassia alata (Senna alata) has been used traditionally as a remedy for a variety of health issues. Cassia alata is also known as ringworm cassia. This plant is perennial and is known as a ‘candle bush’ due to its shape and inflorescences. 
  • 1.7K
  • 08 Feb 2023
Topic Review
Machine Learning for Building Energy Management
Machine learning (ML) algorithms are now part of everyday life, as many technological devices use these algorithms. Machine learning (ML) is now used in many industrial and scientific fields, from aerospace to marketing and advertising. In the architecture, engineering and construction (AEC) sector, ML models and algorithms can be applied to building automation systems (BASs) and building digital twins (BDT) to improve building energy efficiency and flexibility by making use of widely available building operational data. Such systems can automate building management, reducing global consumption of primary resources (i.e., energy and water), increasing indoor comfort, increasing structural safety, and reducing the need for building maintenance. 
  • 1.7K
  • 18 Feb 2024
Topic Review
Net Zero Energy Buildings
Buildings contribute to greenhouse gas emissions that cause environmental impacts on climate change. Net Zero Energy (NZ) buildings would reduce greenhouse gases. The current definition of NZ lacks consensus and has created uncertainties, which cause delays in the adoption of NZ. There is a need to re-evaluate the existing definitions, standards, and requirements to advance the use of renewable technologies, improved energy efficiency, and electrification. This approach will help to speed up achieving the NZ targets.
  • 1.7K
  • 06 Jul 2021
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