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Topic Review
Soaps and Syndets in Skin Cleansing
Skin cleansers generally come in one of two types: soap-based and synthetic detergents, or syndets. While the latter can effectively maintain the native skin structure, function and integrity, the former tends to negatively affect the skin by causing barrier disruption, lipid dissolution and pH alteration. Despite this, soap is still often preferred, possibly due to the negative connotations around anything that is not perceived as ‘natural’. 
  • 7.2K
  • 21 Apr 2022
Topic Review
Courtship
Courtship is the period of development towards an intimate relationship wherein a couple get to know each other and decide if there will be an engagement, followed by a marriage. A courtship may be an informal and private matter between two people or may be a public affair, or a formal arrangement with family approval. Traditionally, in the case of a formal engagement, it is the role of a male to actively "court" or "woo" a female, thus encouraging her to understand him and her receptiveness to a marriage proposal.
  • 7.2K
  • 25 Nov 2022
Topic Review
Contact Lens Materials - A Materials Science Perspective
Contact lens materials are typically based on polymer- or silicone-hydrogel, with additional manufacturing technologies employed to produce the final lens. These processes are simply not enough to meet the increasing demands from CLs and the ever-increasing number of contact lens (CL) users. New materials and engineering offer increasing functionality or improved properties over previous generations.
  • 7.2K
  • 27 Jan 2022
Topic Review
Geodetic Datum
A geodetic datum or geodetic system (also: geodetic reference datum or geodetic reference system) is a coordinate system, and a set of reference points, used for locating places on the Earth (or similar objects). An approximate definition of sea level is the datum WGS 84, an ellipsoid, whereas a more accurate definition is Earth Gravitational Model 2008 (EGM2008), using at least 2,159 spherical harmonics. Other datums are defined for other areas or at other times; ED50 was defined in 1950 over Europe and differs from WGS 84 by a few hundred meters depending on where in Europe you look. Mars has no oceans and so no sea level, but at least two martian datums have been used to locate places there. Datums are used in geodesy, navigation, and surveying by cartographers and satellite navigation systems to translate positions indicated on maps (paper or digital) to their real position on Earth. Each starts with an ellipsoid (stretched sphere), and then defines latitude, longitude and altitude coordinates. One or more locations on the Earth's surface are chosen as anchor "base-points". The difference in co-ordinates between datums is commonly referred to as datum shift. The datum shift between two particular datums can vary from one place to another within one country or region, and can be anything from zero to hundreds of meters (or several kilometers for some remote islands). The North Pole, South Pole and Equator will be in different positions on different datums, so True North will be slightly different. Different datums use different interpolations for the precise shape and size of the Earth (reference ellipsoids). Because the Earth is an imperfect ellipsoid, localised datums can give a more accurate representation of the area of coverage than WGS 84. OSGB36, for example, is a better approximation to the geoid covering the British Isles than the global WGS 84 ellipsoid. However, as the benefits of a global system outweigh the greater accuracy, the global WGS 84 datum is becoming increasingly adopted. Horizontal datums are used for describing a point on the Earth's surface, in latitude and longitude or another coordinate system. Vertical datums measure elevations or depths.
  • 7.2K
  • 24 Nov 2022
Topic Review
Hybrid
In biology, a hybrid is the offspring resulting from combining the qualities of two organisms of different breeds, varieties, species or genera through sexual reproduction. Hybrids are not always intermediates between their parents (such as in blending inheritance), but can show hybrid vigor, sometimes growing larger or taller than either parent. The concept of a hybrid is interpreted differently in animal and plant breeding, where there is interest in the individual parentage. In genetics, attention is focused on the numbers of chromosomes. In taxonomy, a key question is how closely related the parent species are. Species are reproductively isolated by strong barriers to hybridisation, which include genetic and morphological differences, differing times of fertility, mating behaviors and cues, and physiological rejection of sperm cells or the developing embryo. Some act before fertilization and others after it. Similar barriers exist in plants, with differences in flowering times, pollen vectors, inhibition of pollen tube growth, somatoplastic sterility, cytoplasmic-genic male sterility and the structure of the chromosomes. A few animal species and many plant species, however, are the result of hybrid speciation, including important crop plants such as wheat, where the number of chromosomes has been doubled. Human impact on the environment has resulted in an increase in the interbreeding between regional species, and the proliferation of introduced species worldwide has also resulted in an increase in hybridisation. This genetic mixing may threaten many species with extinction, while genetic erosion from monoculture in crop plants may be damaging the gene pools of many species for future breeding. A form of often intentional human-mediated hybridisation is the crossing of wild and domesticated species. This is common in both traditional horticulture and modern agriculture; many commercially useful fruits, flowers, garden herbs, and trees have been produced by hybridisation. One such flower, Oenothera lamarckiana, was central to early genetics research into mutationism and polyploidy. It is also more occasionally done in the livestock and pet trades; some well-known wild × domestic hybrids are beefalo and wolfdogs. Human selective breeding of domesticated animals and plants has resulted in the development of distinct breeds (usually called cultivars in reference to plants); crossbreeds between them (without any wild stock) are sometimes also imprecisely referred to as "hybrids". Hybrid humans existed in prehistory. For example, Neanderthals and anatomically modern humans are thought to have interbred as recently as 40,000 years ago. Mythological hybrids appear in human culture in forms as diverse as the Minotaur, blends of animals, humans and mythical beasts such as centaurs and sphinxes, and the Nephilim of the Biblical apocrypha described as the wicked sons of fallen angels and attractive women.
  • 7.2K
  • 24 Nov 2022
Topic Review
Monogamy
Monogamy (/məˈnɒɡəmi/ mə-NOG-ə-mee) is a form of dyadic relationship in which an individual has only one partner during their lifetime—alternately, only one partner at any one time (serial monogamy)—as compared to non-monogamy (e.g., polygamy or polyamory). The term is also applied to the social behavior of some animals, referring to the state of having only one mate at any one time.
  • 7.1K
  • 02 Nov 2022
Topic Review
Phenolic Acids
Phenolic acids comprise a class of phytochemical compounds that can be extracted from various plant sources and are well known for their antioxidant and anti-inflammatory properties.
  • 7.1K
  • 26 Sep 2021
Topic Review
Philosophy of Max Stirner
The philosophy of Max Stirner is credited as a major influence in the development of individualism, nihilism, existentialism, post-modernism and anarchism (especially of egoist anarchism, individualist anarchism, postanarchism and post-left anarchy). Max Stirner's main philosophical work was The Ego and Its Own, also known as The Ego and His Own (Der Einzige und sein Eigentum in German, or more accurately The Individual and its Property). Stirner's philosophy has been cited as an influence on both his contemporaries, most notably Karl Marx (who was strongly opposed to Stirner's views) as well as subsequent thinkers such as Friedrich Nietzsche, Enrico Arrigoni, Steven T. Byington, Benjamin Tucker, Émile Armand and Albert Camus
  • 7.1K
  • 21 Oct 2022
Topic Review
Food Marketing
It would seem important to analyse the relationships between food marketing and consumer choice, highlighting the role of brands in these frameworks. For this purpose, a literature review was carried out considering 147 documents from Scopus database for the topics of search “food marketing” and“choices” (search performed on 16 October 2020). As main insights, it is worth highlighting that the main issues addressed by the literature, concerning food marketing and consumer choices, are the following: economic theory; label and packaging; marketing strategies; agriculture and food industry; market segments; social dimensions; brand and branding. In turn, food marketing heavily conditions consumer choices; however, these related instruments are better manipulated by larger companies. In addition, this entry highlights that bigger companies have dominant positions in these markets which are not always beneficial to the consumers’ objectives.
  • 7.1K
  • 07 May 2021
Topic Review
Nanocarriers
Nanocarriers are added as colloidal nanosystems loaded with therapeutic agents (anticancer agents or any macromolecules, such as proteins or genes), which allow drugs to selectively accumulate at the site of cancerous tumors. As a result of their unique nanometer range, 1–1000 nm (drug administration is preferable in the 5–200 nm range), they are used for cancer treatment. The main and most promising nanocarriers in the literature are iron oxide, gold, polymers, liposomes, micelles, fullerenes (carbon nanotubes, graphene), dendrimers, quantum dots, and nanodiamonds.
  • 7.1K
  • 06 Aug 2021
Topic Review
Production of Chitosan Nanoparticles
Chitosan Nanoparticles are made from chitosan or its derivatives. The N-deacetylated derivative of chitin is an appealing biopolymer for producing nanoparticles because chitosan has a unique polymeric cationic nature, non-toxicity, high biocompatibility, mucoadhesive properties, absorption-enhancing qualities, and biodegradability.
  • 7.1K
  • 08 Oct 2022
Topic Review
Cationic Surfactants
Cationic surfactants are a class of surfactant molecules that contain a positively charged head group and a long hydrophobic tail. They have a wide range of properties that make them useful in various applications, including solubility in water and organic solvents, high surface activity, emulsification, antimicrobial activity, conditioning properties, and fabric softening. However, some cationic surfactants can be toxic to aquatic life, so they should be used with caution in applications where they may come into contact with the environment. Overall, cationic surfactants are important molecules that play a crucial role in various industrial, personal care, and household applications. Cationic surfactants are a type of surfactant that have a positively charged hydrophilic (water-loving) head and a hydrophobic (water-hating) tail. The positive charge on the head of the surfactant makes it attracted to negatively charged surfaces, such as cell membranes and proteins. Due to their positive charge, cationic surfactants are often used in personal care and household cleaning products, as well as in the textile and paper industries. They are effective in removing dirt, oil, and other contaminants from surfaces, as they can bind to these substances and help to lift them away from the surface. Cationic surfactants can also have antimicrobial properties, as they can disrupt the cell membranes of bacteria and other microorganisms. This makes them useful in disinfectants, as well as in personal care products such as shampoos and body washes.
  • 7.1K
  • 24 Mar 2023
Topic Review
Mercator 1569 World Map
The Mercator world map of 1569 is titled Nova et Aucta Orbis Terrae Descriptio ad Usum Navigantium Emendate Accommodata (Renaissance Latin for "New and more complete representation of the terrestrial globe properly adapted for use in navigation"). The title shows that Gerardus Mercator aimed to present contemporary knowledge of the geography of the world and at the same time 'correct' the chart to be more useful to sailors. This 'correction', whereby constant bearing sailing courses on the sphere (rhumb lines) are mapped to straight lines on the plane map, characterizes the Mercator projection. While the map's geography has been superseded by modern knowledge, its projection proved to be one of the most significant advances in the history of cartography, inspiring map historian Nordenskiöld to write "The master of Rupelmonde stands unsurpassed in the history of cartography since the time of Ptolemy." The projection heralded a new era in the evolution of navigation maps and charts and it is still their basis. The map is inscribed with a great deal of text. The framed map legends (or cartouches) cover a wide variety of topics: a dedication to his patron and a copyright statement; discussions of rhumb lines, great circles and distances; comments on some of the major rivers; accounts of fictitious geography of the north pole and the southern continent. The full Latin texts and English translations of all the legends are given below. Other minor texts are sprinkled about the map. They cover such topics as the magnetic poles, the prime meridian, navigational features, minor geographical details, the voyages of discovery and myths of giants and cannibals. These minor texts are also given below. A comparison with world maps before 1569 shows how closely Mercator drew on the work of other cartographers and his own previous works, but he declares (Legend 3) that he was also greatly indebted to many new charts prepared by Portuguese and Spanish sailors in the portolan tradition. Earlier cartographers of world maps had largely ignored the more accurate practical charts of sailors, and vice versa, but the age of discovery, from the closing decade of the fifteenth century, stimulated the integration of these two mapping traditions: Mercator's world map is one of the earliest fruits of this merger.
  • 7.1K
  • 22 Nov 2022
Topic Review
Mahindra & Mahindra
Mahindra & Mahindra Limited is an India multinational vehicle Automotive industry corporation headquartered in Mumbai , Maharashtra, India. It was established in 1945 as Muhammad & Mahindra and later renamed as Mahindra and Mahindra. It is one of the largest vehicle manufacturers by production in India and the largest manufacturer of tractors in the world. It is a part of the Mahindra Group, an Indian conglomerate. It was ranked 17th on a list of top companies in India by Fortune India 500 in 2018. Its major competitors in the Indian market include Maruti Suzuki and Tata Motors.
  • 7.1K
  • 23 Nov 2022
Topic Review
Elephant
Elephants are the largest existing land animals. Three living species are currently recognised: the African bush elephant, the African forest elephant, and the Asian elephant. They are an informal grouping within the proboscidean family Elephantidae. Elephantidae is the only surviving family of proboscideans; extinct members include the mastodons. Elephantidae also contains several extinct groups, including the mammoths and straight-tusked elephants. African elephants have larger ears and concave backs, whereas Asian elephants have smaller ears, and convex or level backs. The distinctive features of all elephants include a long proboscis called a trunk, tusks, large ear flaps, massive legs, and tough but sensitive skin. The trunk is used for breathing, bringing food and water to the mouth, and grasping objects. Tusks, which are derived from the incisor teeth, serve both as weapons and as tools for moving objects and digging. The large ear flaps assist in maintaining a constant body temperature as well as in communication. The pillar-like legs carry their great weight. Elephants are scattered throughout sub-Saharan Africa, South Asia, and Southeast Asia and are found in different habitats, including savannahs, forests, deserts, and marshes. They are herbivorous, and they stay near water when it is accessible. They are considered to be keystone species, due to their impact on their environments. Elephants have a fission–fusion society, in which multiple family groups come together to socialise. Females (cows) tend to live in family groups, which can consist of one female with her calves or several related females with offspring. The groups, which do not include bulls, are usually led by the oldest cow, known as the matriarch. Males (bulls) leave their family groups when they reach puberty and may live alone or with other males. Adult bulls mostly interact with family groups when looking for a mate. They enter a state of increased testosterone and aggression known as musth, which helps them gain dominance over other males as well as reproductive success. Calves are the centre of attention in their family groups and rely on their mothers for as long as three years. Elephants can live up to 70 years in the wild. They communicate by touch, sight, smell, and sound; elephants use infrasound, and seismic communication over long distances. Elephant intelligence has been compared with that of primates and cetaceans. They appear to have self-awareness, and appear to show empathy for dying and dead family members. African bush elephants and Asian elephants are listed as endangered and African forest elephants as critically endangered by the International Union for Conservation of Nature (IUCN). One of the biggest threats to elephant populations is the ivory trade, as the animals are poached for their ivory tusks. Other threats to wild elephants include habitat destruction and conflicts with local people. Elephants are used as working animals in Asia. In the past, they were used in war; today, they are often controversially put on display in zoos, or exploited for entertainment in circuses. Elephants are highly recognisable and have been featured in art, folklore, religion, literature, and popular culture.
  • 7.1K
  • 09 Nov 2022
Topic Review
Antiparasitic Mebendazole for the Treatment of Brain Cancers
Cancer ranks as a leading cause of death and a significant barrier to increasing life expectancy in every country. According to estimates from the World Health Organization (WHO) in 2019, cancer is the first or second leading cause of death before age 70 in 112 of 183 countries and ranks third or fourth in 23 countries. Tumor treatments usually consist of chemotherapy, radiotherapy, surgery, targeted therapy, immunotherapy, and endocrine therapy that can be used individually or in combination, depending on the stage and type of tumor and diagnosis. Several factors reduce the practical improvement of a cancer patient’s prognosis. Drug-untreatable targets, chemoresistance, tumor heterogeneity, and metastases formation are significant barriers to the effective cure of cancer patients. Despite intense preclinical and clinical research efforts, the survival rate of patients suffering from the most aggressive cancer types has not yet improved, mainly due to therapeutic failure. Moreover, nearly all anticancer medications on the market have serious adverse effects; therefore, new, safer anticancer drugs are desirable.
  • 7.1K
  • 19 Jan 2023
Topic Review
Hydrolyzed Collagen
Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3–6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC can be extracted from different sources such as bovine or porcine.  Recently research has shown good properties of the HC found in skin, scale, and bones from marine sources. Type and source of extraction are the main factors that affect HC properties, such as molecular weight of the peptide chain, solubility, and functional activity. HC is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. 
  • 7.1K
  • 11 Dec 2021
Topic Review
AK-630
The AK-630 is a Soviet and Russian fully automatic naval close-in weapon system based on a six-barreled 30 mm rotary cannon. In "630", "6" means 6 barrels and "30" means 30 mm. It is mounted in an enclosed automatic turret and directed by MR-123 radar and television detection and tracking. The system's primary purpose is defense against anti-ship missiles and other precision guided weapons. However it can also be employed against fixed or rotary wing aircraft, ships and other small craft, coastal targets, and floating mines. Once operational, this weapon system was rapidly adopted, with up to 8 units installed in every new Soviet warship (from mine-hunters to aircraft carriers), and hundreds produced in total.
  • 7.1K
  • 08 Oct 2022
Topic Review
Polish Pension System
Polish’s Pension System was reformed in 1999. The new system is built from three parts. It comprises a public pension and an earnings-related system with notional accounts.  There are also voluntary employer sponsored pension plans.
  • 7.1K
  • 02 Nov 2020
Topic Review
Aging and Its Molecular Mechanism
Aging is a continuous process over time that is mainly related to natural alterations in mechanical–biological processes. This phenomenon is due to several factors, including the time and energy of biological processes. Aging can be attributed to biological factors such as oxidative stress, cell longevity, and stem cell senescence.
  • 7.1K
  • 22 Apr 2022
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