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Topic Review
Fabrication of Nanoporous Anodic Alumina 
The fabrication of a thick oxide layer onto an aluminum surface via anodization has been a subject of intense research activity for more than a century, largely due to protective and decorative applications. The capability to create well-defined pores via a cost-effective electrochemical oxidation technique onto the surface has made a major renaissance in the field, as the porous surfaces exhibit remarkably different properties compared to a bulk oxide layer. Amongst the various nanoporous structures being investigated, nanoporous anodic alumina (NAA) with well-organized and highly ordered hexagonal honeycomb-like pores has emerged as the most popular nanomaterial due to its wide range of applications, ranging from corrosion resistance to bacterial repelling surfaces.
  • 1.8K
  • 07 May 2022
Topic Review
Mental Health of Czech University Psychology Students
High rates of mental health problems are a growing concern in Czech higher education, negatively impacting students’ performance and wellbeing. Despite the serious nature of poor mental health, students often do not seek help because of negative attitudes and shame over mental health problems. 
  • 1.8K
  • 09 May 2022
Topic Review
2019–2020 Vaping Lung Illness Outbreak
Template:Infobox outbreak An outbreak of severe vaping-associated lung illness starting in 2019 is ongoing among users of cannabis vaping products, almost exclusively in the United States. The first cases were identified in Illinois and Wisconsin in April 2019; as of January 21, 2020, a total of 2,711 hospitalized cases, including 60 deaths have been confirmed by the U.S. Centers for Disease Control. Cases peaked in September 2019, and have been slowly declining since. CDC investigators identified direct exposure to chemicals present in vaping products as responsible for the outbreak. Vitamin E acetate is a very strong culprit of concern in the lung illnesses related to THC-based vaping products, but the CDC did not rule out other chemicals as possible causes. Though patients have reported using vaping products containing THC, nicotine, or both types, about 86% of patients studied by the CDC admitted THC use. The majority of those affected were young adults 18-34, which is the group with the greatest prevalence of cannabis use in the US. Nicotine-containing products are regulated in the U.S. by the Food and Drug Administration; THC products are illegal under federal law, but allowed and regulated by some states. Prior to the outbreak, vitamin E acetate was used in low concentrations, or lower than 20% of the formula in vape cartridges, as a thickening agent. As a result of a limited availability of cannabis in California as well as high demand, illicit sellers had used about 50% or higher of diluent thickeners in their formulas to bulk up tiny potency vape cartridges, and vitamin E acetate is a common choice because it resembles THC oil. Some jurisdictions took action to restrict the sale of products containing vitamin E acetate and other chemicals in response to the outbreak, but THC products in states where it is illegal and some nictotine-containing products are produced illegally (and sometimes obtained illegally in jurisdictions where legal, by underage consumers).
  • 1.8K
  • 30 Sep 2022
Topic Review
Charles Stark Draper Laboratory
Draper is an United States not-for-profit research and development organization, headquartered in Cambridge, Massachusetts; its official name is "The Charles Stark Draper Laboratory, Inc". The laboratory specializes in the design, development, and deployment of advanced technology solutions to problems in national security, space exploration, health care and energy. The laboratory was founded in 1932 by Charles Stark Draper at the Massachusetts Institute of Technology (MIT) to develop aeronautical instrumentation, and came to be called the "MIT Instrumentation Laboratory". It was renamed for its founder in 1970 and separated from MIT in 1973 to become an independent, non-profit organization. The expertise of the laboratory staff includes the areas of guidance, navigation, and control technologies and systems; fault-tolerant computing; advanced algorithms and software solutions; modeling and simulation; and microelectromechanical systems and multichip module technology.
  • 1.8K
  • 14 Oct 2022
Topic Review
Bloc Party (Politics)
A bloc party (German: Blockpartei) in politics may refer to a political party that is a constituent member of an electoral bloc. However, this term also has a more specific meaning, referring to non-ruling but legal political parties in an authoritarian or totalitarian regime (most notably communist regimes) as auxiliary parties and members of a ruling coalition, differing such governments from pure one-party states such as Nazi Germany and the Soviet Union, although such minor parties rarely if ever constitute opposition parties or alternative sources of power. Sometimes, a bloc party is called a satellite party.
  • 1.8K
  • 21 Oct 2022
Topic Review
The Dangers of Travel—Banditry on the Roads
Since the dawn of time, one of the main barriers to travel has been the fear of leaving one’s place of residence and travelling into a foreign unknown and dangerous space. However, at the same time, firmly rooted in human nature is the desire to know and experience travel, this archetypal inner need is the motive for undertaking travel. In the past, in ancient times, it was difficult to travel safely, not always succeeding in avoiding dangerous areas and being among the friendly inhabitants of distant countries. In modern times, too, travel is dangerous and no traveler can have the comfort of carefree travel until the end.
  • 1.8K
  • 30 Dec 2022
Topic Review
Spore-Forming Probiotics for Poultry
One of the main problems in the poultry industry is the search for a viable replacement for antibiotic growth promoters. This issue requires a “one health” approach because the uncontrolled use of antibiotics in poultry can lead to the development of antimicrobial resistance, which is a concern not only in animals, but for humans as well. One of the promising ways to overcome this challenge is found in probiotics due to their wide range of features and mechanisms of action for health promotion. Moreover, spore-forming probiotics are suitable for use in the poultry industry because of their unique ability, encapsulation, granting them protection from the harshest conditions and resulting in improved availability for hosts’ organisms. 
  • 1.8K
  • 19 Jul 2021
Topic Review
Antimicrobial and Biocidal Resistance
Antimicrobial resistance (AMR) is now recognised as a major public health crisis as essential antimicrobial drugs including antibiotics, antifungals, antivirals, antimalarials and anthelmintics become less effective therapeutic options. Biocides, which are chemicals used as sanitizers and disinfectants, consist of specific formulations containing one or more active ingredients that nonspecifically and fatally target microbial species. Antimicrobial resistance is one of the greatest dangers to public health of the 21st century, threatening the treatment and prevention of infectious diseases globally. Disinfection, the elimination of microbial species via the application of biocidal chemicals, is essential to control infectious diseases and safeguard animal and human health. In an era of antimicrobial resistance and emerging disease, the effective application of biocidal control measures is vital to protect public health. 
  • 1.8K
  • 01 Jun 2021
Topic Review
Glycans on Cell Surface Receptors
Cells undergo proliferation and apoptosis, migration and differentiation via a number of cell surface receptors, most of which are heavily glycosylated.We discuss the structures and roles of glycan chains of receptors to better understand their regulation in cell survival and cell death.
  • 1.8K
  • 10 Jun 2021
Topic Review
Cadmium in Plants
Cd is a naturally occurring environmental toxicant, which is easily absorbed and accumulated by plants, and has strong teratogenic and mutagenic effects on organisms. Human exposure to Cd for a long time can easily cause diseases such as osteoporosis and kidney damage. It is also positively correlated with the outbreak of a variety of cancers, and is classified as a human carcinogen by the International Agency for Research on Cancer (Group I). A large amount of data shows that the intake of Cd in the human body is mainly from the diet. Therefore, it is very important to understand the influx and transport mechanism of Cd in plants.
  • 1.8K
  • 17 Feb 2022
Topic Review
Urban Agriculture in the Interior Design Studio
Urban agriculture as an alternative solution can reduce the future burden on agriculture sector. As a response to this issue, the interior architecture design studio-V (INT 401) proposes a futuristic vision which is based on the notion of urban agriculture. This vision requires a pedagogical framework to be defined for the interior design studio-V. 
  • 1.8K
  • 27 Jun 2022
Topic Review
Material Reactions, Degradation and Applications of Polyvinylidene Fluoride
Polyvinylidene fluoride (PVDF), the chemical formula is (C2H2F2)n. Its basic building blocks are therefore carbon, hydrogen, and fluorine. These three elements can form several crystalline chain conformations. Conformations are defined by polar and nonpolar phases. Four phases are most commonly found in the literature: α-, β-, γ-, and δ-. 
  • 1.8K
  • 17 Oct 2022
Topic Review
Time Series Classification Techniques Used in Biomedical Applications
Time series classification (TSC) is very commonly used for modeling digital clinical measures. Time Series Classification (TSC) involves building predictive models that output a target variable or label from inputs of longitudinal or sequential observations across some time period. These inputs could be from a single variable or multiple variables measured across time, where the measurements can be ordinal or numerical (discrete or continuous).
  • 1.8K
  • 07 Nov 2022
Topic Review
Heckler & Koch HK69A1
The HK69A1 is a 40 mm grenade launcher developed and produced by the German arms manufacturer Heckler & Koch (H&K). The weapon was designed to engage enemy troops and strongpoints out to a distance of 350 m; it can also be used to deploy smoke grenades and illumination flares.
  • 1.8K
  • 05 Nov 2022
Biography
Hertha Sponer
Hertha Sponer (1 September 1895 – 27 February 1968) was a German physicist and chemist who contributed to modern quantum mechanics and molecular physics and was the first woman on the physics faculty of Duke University. She was the older sister of philologist and resistance fighter Margot Sponer.[1] Sponer was born in Neisse (Nysa), Prussian Silesia, and obtained her high school degree in N
  • 1.8K
  • 22 Nov 2022
Topic Review
American Foulbrood
American foulbrood (AFB) is exclusively an infectious disease of honey bee larvae (Apis mellifera) and their subspecies that is spread easily and rapidly and is often present in apiaries. Due to the resistance and pathogenicity of the bacterial causative agent of the disease, which has considerable epizootiological and economic significance for beekeeping, AFB was classified as a highly dangerous, infectious animal disease by the World Organization for Animal Health (WOAH). Considering the severity of the infection, a frequent occurrence, rapid and easy spread, epizooty and enzooty are common. 
  • 1.8K
  • 09 Mar 2023
Topic Review
Fucoxanthin
Fucoxanthin is a well-known carotenoid of the xanthophyll family, mainly produced by marine organisms such as the macroalgae of the fucus genus or microalgae such as Phaeodactylum tricornutum. Fucoxanthin has antioxidant and anti-inflammatory properties but also several anticancer effects. Fucoxanthin induces cell growth arrest, apoptosis, and/or autophagy in several cancer cell lines as well as in animal models of cancer. Fucoxanthin treatment leads to the inhibition of metastasis-related migration, invasion, epithelial–mesenchymal transition, and angiogenesis. Fucoxanthin also affects the DNA repair pathways, which could be involved in the resistance phenotype of tumor cells. Moreover, combined treatments of fucoxanthin, or its metabolite fucoxanthinol, with usual anticancer treatments can support conventional therapeutic strategies by reducing drug resistance.
  • 1.8K
  • 03 Jun 2021
Topic Review
CRISPR-Cas9 in Fruit and Vegetable
Fruit and vegetable crops are rich in dietary fibre, vitamins and minerals, which are vital to human health. However, many biotic stressors (such as pests and diseases) and abiotic stressors threaten crop growth, quality, and yield. Traditional breeding strategies for improving crop traits include a series of backcrosses and selection to introduce beneficial traits into fine germplasm, this process is slow and resource-intensive. The new breeding technique known as clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein-9 (Cas9) has the potential to improve many traits rapidly and accurately, such as yield, quality, disease resistance, abiotic stress tolerance, and nutritional aspects in crops. Because of its simple operation and high mutation efficiency, this system has been applied to obtain new germplasm resources via gene-directed mutation.
  • 1.8K
  • 04 Aug 2021
Topic Review
Antitumour Activity of Natural Products Containing Isoxazole/Isoxazoline Moiety
Isoxazoles and isoxazolines are five-membered heterocyclic molecules containing nitrogen and oxygen. Isoxazole and isoxazoline are the most popular heterocyclic compounds for developing novel drug candidates. As biosynthetic technology has advanced, A growing number of natural products are being developed for cancer therapy as clinical candidates. As a result, scientists have created several isoxazole and isoxazoline derivatives with anti-cancer properties based on natural products.
  • 1.8K
  • 09 Feb 2023
Topic Review
Notch Signaling in Inflammatory Diseases
Notch signaling, a highly conserved pathway in mammals, is crucial for differentiation and homeostasis of immune cells. The spectrum of diseases is as broad as the cellular functions controlled by Notch signaling. In various types of cancer, cerebrovascular diseases, and inherited disease syndromes, Notch signaling has been found to exert a detrimental impact as well as in inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus (SLE), systemic sclerosis (SSc), primary biliary cirrhosis, and atherosclerosis. 
  • 1.8K
  • 17 Feb 2023
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