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Topic Review
Complex Lymphatic Anomalies
Complex Lymphatic Anomalies (CLA) are characterized by idiopathic boney lesions caused by abnormal lymphatic invasion. The lymphatic network is a one-way system mainly responsible for maintaining fluid homeostasis, lipid absorption, and immune surveillance. CLAs include four diseases with overlapping and distinct clinical features: Gorham-Stout Disease (GSD), General Lymphatic Anomaly (GLA), Kaposiform Lymphangiomatosis (KLA), and Central Conducting Lymphatic Anomaly (CCLA).In order to highlight the known bone involvement of each CLA, their osteopathic phenotypes are described and illustrated below.
  • 1.8K
  • 17 Aug 2022
Topic Review
Ursa Major Moving Group
The Ursa Major Moving Group, also known as Collinder 285 and the Ursa Major association, is the closest stellar moving group – a set of stars with common velocities in space and thought to have a common origin in space and time. In the case of the Ursa Major group, all the stars formed about 300 million years ago. Its core is located roughly 80 light years away and part of the Local Bubble. It is rich in bright stars including most of the stars of the Big Dipper.
  • 1.8K
  • 14 Oct 2022
Topic Review
Molecular Analyses for Ancient Parchment Documentary Materials
A new trend is molecular analysis, which has given rise to the emerging field of biocodicology, comprising protein and DNA analysis for the identification of the biological origin of the skins used for their manufacture. In addition, DNA analysis can identify the microbiome present in the object under investigation, which adds value by providing information on its history and state of preservation. 
  • 1.8K
  • 01 Nov 2022
Topic Review
SIMD
Single instruction, multiple data (SIMD) is a type of parallel processing in Flynn's taxonomy. SIMD can be internal (part of the hardware design) and it can be directly accessible through an instruction set architecture (ISA): it should not be confused with an ISA. SIMD describes computers with multiple processing elements that perform the same operation on multiple data points simultaneously. Such machines exploit data level parallelism, but not concurrency: there are simultaneous (parallel) computations, but each unit performs the exact same instruction at any given moment (just with different data). SIMD is particularly applicable to common tasks such as adjusting the contrast in a digital image or adjusting the volume of digital audio. Most modern CPU designs include SIMD instructions to improve the performance of multimedia use. SIMD has three different subcategories in Flynn's 1972 Taxonomy, one of which is SIMT. SIMT should not be confused with software threads or hardware threads, both of which are task time-sharing (time-slicing). SIMT is true simultaneous parallel hardware-level execution.
  • 1.8K
  • 23 Nov 2022
Topic Review
Morphological Variations of the Liver
Radiologists and oncogynecologists should be familiar with different liver shape variations to avoid diagnostic errors and unwanted intraoperative surgical complications. Surgeons should be aware of variations in liver shape as in such cases, the vasculature or gallbladder may have a variant anatomical location.
  • 1.8K
  • 16 Jan 2024
Topic Review
Causal Loop Diagramming of Socioeconomic Impacts of COVID-19
The complexity, multidimensionality, and persistence of the COVID-19 pandemic have prompted both researchers and policymakers to turn to transdisciplinary methods in dealing with the wickedness of the crisis. While there are increasing calls to use systems thinking to address the intricacy of COVID-19, examples of practical applications of systems thinking are still scarce. We revealed and reviewed eight studies which developed causal loop diagrams (CLDs) to assess the impact of the COVID-19 pandemic on a broader socioeconomic system. We find that major drivers across all studies are the magnitude of the infection spread and government interventions to curb the pandemic, while the most impacted variables are public perception of the pandemic and the risk of infection.
  • 1.8K
  • 23 Nov 2021
Topic Review
Scleroderma (morphea) en Coup de Sabre
Scleroderma (morphea) en coup de sabre is a localized subtype restricted to the frontoparietal region of the head. Localized scleroderma/morphea en coup de sabre (LScs) is a rare form of localized scleroderma that typically affects predominantly children and women. It manifests by presence of linear atrophy and/or hardening of the skin, subcutis, occasionally involving muscles and bones. The early phase lesions appear as an erythematous or violaceous linear indurated mild atrophic plaque and subsequently lesions progress to hypopigmented or depigmented sclerotic deep furrow. It usually starts at the level of the upper eyebrow ridge and reaches the scalp, where a cicatricial alopecia focus appears. There are known descriptions of patients with localized scleroderma en coup de sabre, in whom lesions spread below the eyebrows involving the eyelids, eyelashes, or the skin on the nose. The disease may manifest with ophthalmologic (deformation of eyelids, uveitis, episcleritis) and neurological (convulsions, migraine, trigeminal neuralgia, vascular malformations) symptoms. In some cases neurological symptoms preceded the appearance of skin lesions. Parry Romberg syndrome (also known as progressive facial hemiatrophy), which is a distinct entity within craniofacial linear subtype involving subcutaneous tissue and bones, coexists in 20–40% of patients with en coup de sabre lesions.
  • 1.8K
  • 21 Oct 2021
Topic Review
Vehicular Ad-hoc Network
Vehicular ad-hoc networks (VANETs) are created by applying the principles of mobile ad hoc networks (MANETs) – the spontaneous creation of a wireless network of mobile devices – to the domain of vehicles. VANETs were first mentioned and introduced in 2001 under "car-to-car ad-hoc mobile communication and networking" applications, where networks can be formed and information can be relayed among cars. It was shown that vehicle-to-vehicle and vehicle-to-roadside communications architectures will co-exist in VANETs to provide road safety, navigation, and other roadside services. VANETs are a key part of the intelligent transportation systems (ITS) framework. Sometimes, VANETs are referred as Intelligent Transportation Networks While, in the early 2000s, VANETs were seen as a mere one-to-one application of MANET principles, they have since then developed into a field of research in their own right. By 2015,(p3) the term VANET became mostly synonymous with the more generic term inter-vehicle communication (IVC), although the focus remains on the aspect of spontaneous networking, much less on the use of infrastructure like Road Side Units (RSUs) or cellular networks.
  • 1.8K
  • 11 Oct 2022
Topic Review
Edentulism
Edentulism or toothlessness is the condition of being toothless to at least some degree; in organisms (such as humans) that naturally have teeth (dentition), it is the result of tooth loss. Loss of some teeth is called partial edentulism, whereas loss of all teeth is called complete edentulism. Persons who have lost teeth are (either partially or completely) edentulous (edentate), whereas those who have not lost teeth can be called dentate by comparison. For example, a scientific study may include a partially edentulous group and a healthy dentate control group. Organisms that never possessed teeth can also be described as edentulous, such as members of the former zoological classification order of Edentata, which included anteaters and sloths, all of which possess no anterior teeth and either no or poorly developed posterior teeth. In naturally dentate species, edentulism is more than just the simple presence or absence of teeth; it is biochemically complex, because the teeth, jaws, and oral mucosa are not static objects; they are dynamic (changing over time). Processes such as bone remodeling (loss and gain of bone tissue) in the jaws and inflammation of soft tissue in response to the oral microbiota are clinically important for edentulous people. For example, bone resorption in the jaw is frequently how the teeth were able to detach in the first place; the jaw in an edentulous area undergoes further resorption even after the teeth are gone; and insertion of dental implants can elicit new bone formation, leading to osseointegration. Meanwhile, bacteria and yeasts of the oral cavity and the immune system of their host create an immensely complicated and constantly changing interplay that presents clinically as gingivitis, caries, stomatitis, and other periodontal pathology.
  • 1.8K
  • 18 Oct 2022
Topic Review
Free Recall
Free recall is a common task in the psychological study of memory. In this task, participants study a list of items on each trial, and then are prompted to recall the items in any order. Items are usually presented one at a time for a short duration, and can be any of a number of nameable materials, although traditionally, words from a larger set are chosen. The recall period typically lasts a few minutes, and can involve spoken or written recall. The standard test involves the recall period starting immediately after the final list item; this can be referred to as immediate free recall (IFR) to distinguish it from delayed free recall (DFR). In delayed free recall, there is a short distraction period between the final list item and the start of the recall period. Both IFR and DFR have been used to test certain effects that appear during recall tests, such as the primacy effect and recency effect.
  • 1.8K
  • 04 Nov 2022
Topic Review
Cylinder (Engine)
A cylinder is the central working part of a reciprocating engine or pump, the space in which a piston travels. Multiple cylinders are commonly arranged side by side in a bank, or engine block, which is typically cast from aluminum or cast iron before receiving precision machine work. Cylinders may be sleeved (lined with a harder metal) or sleeveless (with a wear-resistant coating such as Nikasil). A sleeveless engine may also be referred to as a "parent-bore engine". A cylinder's displacement, or swept volume, can be calculated by multiplying its cross-sectional area (the square of half the bore by pi) by the distance the piston travels within the cylinder (the stroke). The engine displacement can be calculated by multiplying the swept volume of one cylinder by the number of cylinders. Presented symbolically, A piston is seated inside each cylinder by several metal piston rings fitted around its outside surface in machined grooves; typically two for compressional sealing and one to seal the oil. The rings make near contact with the cylinder walls (sleeved or sleeveless), riding on a thin layer of lubricating oil; essential to keep the engine from seizing and necessitating a cylinder wall's durable surface. During the earliest stage of an engine's life, its initial breaking-in or running-in period, small irregularities in the metals are encouraged to gradually form congruent grooves by avoiding extreme operating conditions. Later in its life, after mechanical wear has increased the spacing between the piston and the cylinder (with a consequent decrease in power output) the cylinders may be machined to a slightly larger diameter to receive new sleeves (where applicable) and piston rings, a process sometimes known as reboring.
  • 1.8K
  • 06 Dec 2022
Biography
Émile Benveniste
Émile Benveniste (French: [bɛ̃vǝnist]; 27 May 1902 – 3 October 1976) was a France structural linguist and semiotician. He is best known for his work on Indo-European languages and his critical reformulation of the linguistic paradigm established by Ferdinand de Saussure. Benveniste was born in Aleppo, Aleppo Vilayet, Ottoman Syria to a Sephardi family. His father sent him to Paris to u
  • 1.8K
  • 30 Dec 2022
Topic Review
Pulsed Electric Field Applications for Food Waste Extraction
The food processing industry is a continuously developing sector that uses innovative technologies to efficiently process food products. During processing, food industries generate substantial amounts of by-products in the form of waste materials. This food waste consists of organic matter rich in bioactive compounds, such as polyphenols, carotenoids, and flavonoids. Improper management of food waste can adversely affect both the environment and human health, leading to environmental pollution and the release of greenhouse gas emissions. Thus, proper food waste management has become an urgent global issue. The presence of bioactive compounds (mainly polyphenols, flavonoids, and anthocyanins, but also carotenoids, alkaloids, proteins, lipids, and carbohydrates) in food waste holds the potential to transform them into valuable resources. Several sectors, including food and energy, have recognized food waste as an innovative source. 
  • 1.8K
  • 20 Nov 2023
Topic Review
Highly Dispersed Metal Catalysts
Single-atom catalysts (SACs), consisting of metals atomically dispersed on a support, are considered as advanced materials bridging homogeneous and heterogeneous catalysis, representing the catalysis at the limit. The enhanced performance of these catalysts is due to the combination of distinct factors such as well-defined active sites, comprising metal single atoms in different coordination environments also varying its valence state and strongly interacting with the support, in this case porous carbons, maximizing then the metal efficiency in comparison with other metal surfaces consisting of metal clusters and/or metal nanoparticles.
  • 1.8K
  • 06 Apr 2021
Topic Review
Probiotics in Obesity and IBD
The Firmicutes/Bacteroidetes (F/B) ratio is widely accepted to have an important influence in maintaining normal intestinal homeostasis. Increased or decreased F/B ratio is regarded as dysbiosis, whereby the former is usually observed with obesity, and the latter with inflammatory bowel disease (IBD). Probiotics as live microorganisms can confer health benefits to the host when administered in adequate amounts. There is considerable evidence of their nutritional and immunosuppressive properties including reports that elucidate the association of probiotics with the F/B ratio, obesity, and IBD. Orally administered probiotics can contribute to the restoration of dysbiotic microbiota and to the prevention of obesity or IBD. However, as the effects of different probiotics on the F/B ratio differ, selecting the appropriate species or mixture is crucial.
  • 1.8K
  • 19 Nov 2020
Topic Review
Natural Bioactive Compounds: Toxicity/Safety Concerns
Although synthetic bioactive compounds are approved in many countries for food applications, they are becoming less and less welcome by consumers. Therefore, there has been an increasing interest in replacing these synthetic compounds by natural bioactive compounds. These natural compounds can be used as food additives to maintain the food quality, food safety and appeal, and as food supplements or nutraceuticals to correct nutritional deficiencies, maintain a suitable intake of nutrients, or to support physiological functions, respectively. Recent studies reveal that numerous food wastes, particularly fruit and vegetables byproducts, are a good source of bioactive compounds that can be extracted and reintroduced into the food chain as natural food additives or in food matrices for obtaining nutraceuticals and functional foods. This entry addresses general questions concerning the use of fruit and vegetables byproducts as new sources of natural bioactive compounds that are being addressed to foods as natural additives and supplements. Those bioactive compounds must follow the legal requirements and evaluations to assess the risks for human health and their toxicity must be considered before being launched into the market. To overcome the potential health risk while increasing the biological activity, stability and biodistribution of the supplements’ technological alternatives have been studied such as encapsulation of bioactive compounds into micro or nanoparticles or nanoemulsions. This will allow enhancing the stability and release along the gastrointestinal tract in a controlled manner into the specific tissues. This review summarizes the valorization path that a bioactive compound recovered from an agro-food waste can face from the moment their potentialities are exhibited until it reaches the final consumer and the safety and toxicity challenges, they may overcome.
  • 1.8K
  • 23 Jul 2021
Topic Review
NcRNAs with Regulatory Functions
Noncoding RNAs (ncRNAs) play prominent roles in the regulation of gene expression via their interactions with other biological molecules such as proteins and nucleic acids.
  • 1.8K
  • 12 Nov 2021
Topic Review
Augmented, Virtual and Mixed Reality in Dentistry
Augmented, Virtual and Mixed Reality can represent a useful aids for Dentistry. Augmented Reality can be used to add digital data to real life clinical data. Clinicians can apply Virtual Reality for a digital wax-up that provides a pre-visualization of the final post treatment result. In addition, both these technologies may also be employed to eradicate dental phobia in patients and further enhance patient’s education. Similarly, they can be used to enhance communication between the dentist, patient, and technician. Artificial Intelligence and Robotics can also improve clinical practice. Artificial Intelligence is currently developed to improve dental diagnosis and provide more precise prognoses of dental diseases, whereas Robotics may be used to assist in daily practice. 
  • 1.8K
  • 07 Feb 2022
Topic Review
Fractional Calculus in Electromagnetic Theory
Fractional calculus (FC) was introduced more than 300 years ago as a generalization of classical derivative and integral definitions. It is receiving increasing attention for a growing number of applications in different sciences such as physics, biology, chemistry, engineering, finance, mechanics, optics and, in particular, for modeling physical phenomena related to non-Markovian processes, signal and image processing, dielectric relaxation, viscoelasticity, electromagnetism, control theory, pharmacokinetics, fluids, heat transfer, and so on.
  • 1.8K
  • 27 May 2022
Topic Review
Azadirachta indica (Neem) as a Potential Natural Active
Azadirachta indica (Neem) is a large tree that is native to India and is traditionally used due to its several properties, mainly to treat skin diseases, as well as its “herbicidal” activity. Its bark, leaves, seeds, fruits and flowers are widely used in medicinal treatment due to the presence of active secondary metabolites with biological effects, mainly limonoids and tetranortriterpenoids, such as azadirachtin. Thus, A. indica was studied in a variety of conditions, such as anticancer, antiseptic, anti-inflammatory and chemopreventive agents, as well as a biopesticide. 
  • 1.8K
  • 09 Jun 2022
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