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Topic Review
Windows NT
Windows NT is a proprietary graphical operating system produced by Microsoft, the first version of which was released on July 27, 1993. It is a processor-independent, multiprocessing and multi-user operating system. The first version of Windows NT was Windows NT 3.1 and was produced for workstations and server computers. It was a commercially focused operating system intended to complement consumer versions of Windows that were based on MS-DOS (including Windows 1.0 through Windows 3.1x). Gradually, the Windows NT family was expanded into Microsoft's general-purpose operating system product line for all personal computers, deprecating the Windows 9x family. "NT" was formerly expanded to "New Technology" but no longer carries any specific meaning. Starting with Windows 2000, "NT" was removed from the product name and is only included in the product version string along with several low-level places within the system. NT was the first purely 32-bit version of Windows, whereas its consumer-oriented counterparts, Windows 3.1x and Windows 9x, were 16-bit/32-bit hybrids. It is a multi-architecture operating system. Initially, it supported several instruction set architectures, including IA-32, MIPS, and DEC Alpha; support for PowerPC, Itanium, x64, and ARM were added later. The latest versions support x86 (including IA-32 and x64) and ARM. Major features of the Windows NT family include Windows Shell, Windows API, Native API, Active Directory, Group Policy, Hardware Abstraction Layer, NTFS, BitLocker, Windows Store, Windows Update, and Hyper-V.
  • 8.0K
  • 02 Nov 2022
Topic Review
Circumscribed Circle
In geometry, the circumscribed circle or circumcircle of a polygon is a circle that passes through all the vertices of the polygon. The center of this circle is called the circumcenter and its radius is called the circumradius. Not every polygon has a circumscribed circle. A polygon that does have one is called a cyclic polygon, or sometimes a concyclic polygon because its vertices are concyclic. All triangles, all regular simple polygons, all rectangles, all isosceles trapezoids, and all right kites are cyclic. A related notion is the one of a minimum bounding circle, which is the smallest circle that completely contains the polygon within it, if the circle's center is within the polygon. Every polygon has a unique minimum bounding circle, which may be constructed by a linear time algorithm. Even if a polygon has a circumscribed circle, it may be different from its minimum bounding circle. For example, for an obtuse triangle, the minimum bounding circle has the longest side as diameter and does not pass through the opposite vertex.
  • 8.0K
  • 15 Nov 2022
Topic Review
Cataracts
A cataract is an ophthalmic disorder characterized by the opacification of the lens and occurs commonly in older people. Age-related cataract is a significant cause of blindness affecting the quality of life worldwide. An imbalance between oxidative stress and antioxidant potential of ocular tissue is considered responsible for structural modifications of crystallins, the protein constituents of the lens, which eventually leads to cataracts. Lutein and zeaxanthin are two major carotenoids which are concentrated in the human lens. Many preclinical and clinical studies provide compelling evidence for a protective role of dietary carotenoids in age-related cataracts.
  • 8.0K
  • 28 Sep 2021
Topic Review
Induction of Polyploidy
Polyploidy has the utmost importance in horticulture for the development of new ornamental varieties with desirable morphological traits referring to plant size and vigor, leaf thickness, larger flowers with thicker petals, intense color of leaves and flowers, long lasting flowers, compactness, dwarfness and restored fertility. Polyploidy may occur naturally due to the formation of unreduced gametes or can be artificially induced by doubling the number of chromosomes in somatic cells.
  • 8.0K
  • 21 Dec 2021
Topic Review
Xbox One System Software
The Xbox One system software, sometimes called the Xbox OS, or Xbox Dashboard (when a person is referring to software updates), is the operating system developed exclusively for the Xbox One consoles. It is a Microsoft Windows-based operating system using the Hyper-V virtual machine monitor and contains separate operating systems for games and applications that can run on the console. It is located on the internal HDD for day-to-day usage, while also being duplicated on the internal NAND storage of the console for recovery purposes and factory reset functionality. The Xbox One allows users to download applications that add to the functionality of the dashboard. From June 2014 onwards, entertainment apps no longer required the user to be signed into a valid Xbox Live Gold account in order to use the features advertised for the given app. Since launch, Microsoft has been updating the OS monthly, with updates downloaded from the Xbox Live service directly to the Xbox One and subsequently installed, or by using offline recovery images downloaded via a PC. In November 2015, a major system update known as the New Xbox One Experience was released, which brought very significant changes to the design and functionality of the system. The Windows 10-based Core had replaced the Windows 8-based one in this update, and the new system is sometimes referred to as "Windows 10 on Xbox One".
  • 8.0K
  • 03 Nov 2022
Topic Review
DNA Excision Repairs and Implication
The physiological impact of the aberrant oxidation products on genomic DNA were demonstrated by embryonic lethality or the cancer susceptibility and/or neurological symptoms of  animal impaired in the base excision repair (BER); the major pathway to maintain genomic integrity against non-bulky DNA oxidation. However, growing evidence suggests that other DNA repair pathways or factors that are not primarily associated with the classical BER pathway are also actively involved in the mitigation of oxidative assaults on the genomic DNA, according to the corresponding types of DNA oxidation. Among others, factors dedicated to lesion recognition in the nucleotide excision repair (NER) pathway have been shown to play eminent roles in the process of lesion recognition and stimulation of the enzyme activity of some sets of BER factors. Besides, substantial bulky DNA oxidation can be preferentially removed by a canonical NER mechanism; therefore, loss of function in the NER pathway shares common features arising from BER defects, including cancer predisposition and neurological disorders, although NER defects generally are nonlethal.
  • 8.0K
  • 30 Oct 2020
Topic Review
Transcaucasia
Transcaucasia, also known as the South Caucasus, is a geographical region on the border of Eastern Europe and Western Asia, straddling the southern Caucasus Mountains. Transcaucasia roughly corresponds to modern Armenia, Georgia and Azerbaijan, and are sometimes collectivelly known as the Caucasian States. The total area of these countries measures about 186,100 square kilometres (71,850 square miles). Transcaucasia and Ciscaucasia (North Caucasus) together comprise the larger Caucasus geographical region that divides Eurasia.
  • 8.0K
  • 23 Nov 2022
Topic Review
Successive Approximation ADC
A successive approximation ADC is a type of analog-to-digital converter that converts a continuous analog waveform into a discrete digital representation via a binary search through all possible quantization levels before finally converging upon a digital output for each conversion.
  • 8.0K
  • 22 Nov 2022
Topic Review
Type 3 Diabetes
The exact connection between Alzheimer’s disease (AD) and type 2 diabetes is still in debate. However, poorly controlled blood sugar may increase the risk of developing Alzheimer’s. This relationship is so strong that some have called Alzheimer’s “diabetes of the brain” or “type 3 diabetes (T3D)”. Given more recent studies continue to indicate evidence linking T3D with AD, this state-of-the-art aimed to demonstrate the relationship between T3D and AD based on the fact that both the processing of amyloid-β (Aβ) precursor protein toxicity and the clearance of Aβ are attributed to impaired insulin signaling, and that insulin resistance mediates the dysregulation of bioenergetics and progress to AD. 
  • 8.0K
  • 29 Oct 2020
Topic Review
Brahmacarya
Brahmacharya (/ˌbrɑːməˈtʃɑːrjə/; Devanagari: ब्रह्मचर्य, Bengali: ব্রহ্মচর্য odia:ବ୍ରହ୍ମଚର୍ଯ୍ୟ lit."pure conduct") is a concept within Indian religions that literally means to stay in conduct within one's own Self. In Yoga, Hinduism and Jainism it generally refers to a lifestyle characterized by sexual continence or complete abstinence. Brahmacharya is somewhat different from the English term "celibacy," which merely means non-indulgence in sexual activity. Brahmacharya is when a person completely controls his body and mind (citta) through ascetic means. In the Hindu, Jain, and Buddhist monastic traditions, brahmacharya implies, among other things, the mandatory renunciation of sex and marriage. It is considered necessary for a monk's spiritual practice. Western notions of the religious life as practiced in monastic settings mirror these characteristics.
  • 7.9K
  • 04 Nov 2022
Topic Review
Math 55
Math 55 is a two-semester long first-year undergraduate mathematics course at Harvard University, founded by Lynn Loomis and Shlomo Sternberg. The official titles of the course are Honors Abstract Algebra (Math 55a) and Honors Real and Complex Analysis (Math 55b). Previously, the official title was Honors Advanced Calculus and Linear Algebra.
  • 7.9K
  • 03 Nov 2022
Biography
Dave Allen
David Tynan O'Mahony (6 July 1936 – 10 March 2005), professionally known as Dave Allen, was an Irish observational comedian[1] and satirist.[2] Initially becoming known in Australia during 1963–64, Allen made regular television appearances in the United Kingdom from the later 1960s and until the mid-1980s. The BBC aired his Dave Allen Show 1972–1986,[3] which was also exported to several
  • 7.9K
  • 15 Nov 2022
Topic Review
Quran Code
The term Quran code (also known as Code 19) refers to the claim that the Quranic text contains a hidden mathematically complex code. Advocates think that the code represents a mathematical proof of the divine authorship of the Quran and they also think that it can be used to identify orthographic errors within the Quranic text. Proponents of the Quran code claim that the Quran code is based on statistical procedures compared to the Bible code, which is ostensibly based on steganography. However, this claim has not been confirmed by any independent mathematical or scientific institute.
  • 7.9K
  • 02 Dec 2022
Topic Review
Luxury Vehicle
A luxury vehicle provides increased levels of comfort, equipment, amenities, quality, performance, and status relative to regular cars for an increased price. The term is subjective and reflects both the qualities of the car and the brand image of its manufacturer. Luxury brands rank above premium brands, though there is no fixed demarcation between the two. Traditionally, most luxury cars were large vehicles, though smaller sports-oriented models were always produced. “Compact“ luxury vehicles such as hatchbacks, and off-road capable sport utility vehicles, are relatively modern trends.
  • 7.9K
  • 27 Oct 2022
Topic Review
List of Mammal Genera
There are currently 1258 genera, 156 families, 28 orders, and around 5937 recognized living species of mammal. Mammalian taxonomy is in constant flux as many new species are described and recategorized within their respective genera and families. The taxonomy represented here is a compilation of the most logical and up-to-date information on mammalian taxonomy from many sources, the main ones being the HMW series and the Mammals Species of the World by Wilson and Reeder.
  • 7.9K
  • 27 Oct 2022
Topic Review
Ropiness in Bread - A Re-Emerging Spoilage Phenomenon
As bread is a very important staple food, its spoilage threatens global food security. Ropy bread spoilage manifests in sticky and stringy degradation of the crumb, slime formation, discoloration, and an odor reminiscent of rotting fruit. Increasing consumer demand for preservative-free products and global warming may increase the occurrence of ropy spoilage. Bacillus amyloliquefaciens, B. subtilis, B. licheniformis, the B. cereus group, B. pumilus, B. sonorensis, Cytobacillus firmus, Niallia circulans, Paenibacillus polymyxa, and Priestia megaterium were reported to cause ropiness in bread. To date, the underlying mechanisms behind ropy bread spoilage remain unclear, high-throughput screening tools to identify rope-forming bacteria are missing, and only a limited number of strategies to reduce rope spoilage were described.
  • 7.9K
  • 26 Oct 2022
Topic Review
Weibo.com
Sina Weibo (NASDAQ: WB) (新浪微博) is a Chinese microblogging (weibo) website. Launched by Sina Corporation on 14 August 2009, it is one of the biggest social media platforms in China, with over 445 million monthly active users as of Q3 2018. The platform has been a huge financial success, with surging stocks, lucrative advertising sales and high revenue and total earnings per quarter. At the start of 2018, it surpassed the US$30 billion market valuation mark for the first time. In March 2014, Sina Corporation announced a spinoff of Weibo as a separate entity and filed an IPO under the symbol WB. Sina carved out 11% of Weibo in the IPO, with Alibaba owning 32% post-IPO. The company began trading publicly on 17 April 2014. In March 2017, Sina launched Sina Weibo International Version. This new version has a clean, concise user interface design, as well as an ad-free feature; while its volume is very small, only occupying one-fifth of the space of the original, it still performs all of the original's functions. In June 2018, Sina Weibo reached 413 million active users. In November 2018, Sina Weibo suspended its registration function for minors under the age of 14. In July 2019, Sina Weibo announced that it would launch a two-month campaign to clean up pornographic and vulgar information, named The Blue Plan. Sina Weibo has attracted criticism over censoring its users.
  • 7.9K
  • 02 Nov 2022
Topic Review
Genome-wide association studies (GWAS)
Genome-wide association studies (GWAS) are studies assessing and analyzing either differences or variations in DNA sequences across the human genome to detect genetic risk factors of diseases prevalent within a target population under study.
  • 7.9K
  • 24 Aug 2020
Topic Review
Anti-COVID-19 potential of Clove phytochemicals
The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for an effective global immunization, the development of a specific therapeutic protocol to treat COVID-19 patients is clearly necessary as a short-term solution of the problem. Drug repurposing and herbal medicine represent two of the most explored strategies for an anti-COVID-19 drug discovery. Clove (Syzygium aromaticum L.) is a well-known culinary spice that has been used for centuries in folk medicine in many disorders. Interestingly, traditional medicines have used clove since ancient times to treat respiratory ailments, whilst clove ingredients show antiviral and anti-inflammatory properties. Other interesting features are the clove antithrombotic, immunostimulatory, and antibacterial effects.
  • 7.9K
  • 13 May 2021
Topic Review
List of ISBN Identifier Groups
This is a list of ISBN identifier groups, the second element in 13-digit ISBNs (the first element in 10-digit ISBNs). The identifier is assigned to mark either a publisher's place of business or the language of the books it publishes. The "original" set of identifiers, assigned prior to the introduction of 13-digit ISBNs and, as such, prior to 978-prefix books, ranged from one to five numerical digits, according to the following structure: They are assigned in approximate descending order of publishing volume. Because the smaller identifiers have room for fewer publishers and ISBNs, several countries have had more than one identifier assigned to them. On the other hand, several countries (Australia, Canada, France, Austria, Switzerland...) have no identifier because they fall in the "language groups". The structure for the identifiers of the 979- prefix and whether it will have language-specific identifiers is not well known, but four identifiers have been assigned (979-10, to France, 979-11, to the Republic of Korea, 979-12, to Italy, and 979-8, to the United States of America). Also, 979-0 has been reserved for the use of International Standard Music Number for sheet music. A 977- prefix indicates International Standard Serial Numbers.
  • 7.9K
  • 28 Oct 2022
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