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Topic Review
Excipients in Pharmaceutical Additive Manufacturing
Additive manufacturing (AM), popularly known as three-dimensional printing (3DP), has been widely applied to the fabrication of prototypes through to functional parts in various manufacturing areas, including the pharmaceutical industry. The term “3D printing” technically refers to a broad collection of additive technologies based on the deposition of materials, like creating objects from the bottom up or layer by layer. Despite the technical differentiation between the terms, “3D printing” has become the common term.
  • 2.1K
  • 28 Feb 2024
Topic Review
Liver Fluke, Blood Fluke Vaccines
Liver flukes (Fasciola spp., Opisthorchis spp, Clonorchis sinensis) and blood flukes (Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in substantial morbidity afflicting millions globally. Affecting the world’s poorest people, fasciolosis, opisthorchiasis, clonorchiasis and schistosomiasis cause severe disability; hinder growth, productivity and cognitive development; and can end in death. Children are often disproportionately affected. F. hepatica and F. gigantica are also the most important trematode flukes parasitising ruminants and cause substantial economic losses annually. Mass drug administration (MDA) programs for the control of these liver and blood fluke infections are in place in a number of countries but treatment coverage is often low, re-infection rates are high and drug compliance and effectiveness can vary. Furthermore, the spectre of drug resistance is ever-present, so MDA is not effective or sustainable long term. Vaccination would provide an invaluable tool to achieve lasting control leading to elimination.
  • 2.1K
  • 12 Oct 2020
Topic Review
Bio-Pigments Synthesized by Marine Bacteria
Marine bacterial species contribute to a significant part of the oceanic population, which substantially produces biologically effectual moieties having various medical and industrial applications. The use of marine-derived bacterial pigments displays a snowballing effect in recent times, being natural, environmentally safe, and health beneficial compounds. Although isolating marine bacteria is a strenuous task, these are still a compelling subject for researchers, due to their promising avenues for numerous applications. Marine-derived bacterial pigments serve as valuable products in the food, pharmaceutical, textile, and cosmetic industries due to their beneficial attributes, including anticancer, antimicrobial, antioxidant, and cytotoxic activities. Biodegradability and higher environmental compatibility further strengthen the use of marine bio-pigments over artificially acquired colored molecules. Besides that, hazardous effects associated with the consumption of synthetic colors further substantiated the use of marine dyes as color additives in industries as well. 
  • 2.1K
  • 06 Jan 2021
Topic Review
Leisure Noise and Hearing Loss
High sound levels capable of permanently damaging the ear are experienced not only in factories and war zones but in concert halls, nightclubs, sports stadiums, and many other leisure environments. This review summarizes evidence that loud music and other forms of “leisure noise” are common causes of noise-induced hearing loss, tinnitus, and hyperacusis, even if audiometric thresholds initially remain within clinically normal limits. Given the huge global burden of preventable noise-induced hearing loss, noise limits should be adopted in a much broader range of settings, and education to promote hearing conservation should be a higher public health priority.
  • 2.1K
  • 27 Apr 2021
Topic Review
Polyurethane
Polyurethane is widely considered as the biggest polymer product which is categorized under plastics. PUs belong to a group of elastomers that are linked to a urethane material with a distinctive feature of being hard and soft parts in the macromolecule. Plastic and modular construction industries produce big quantities of PU wastes in the fabrication process during either processing or utilization of materials.
  • 2.1K
  • 06 Aug 2021
Topic Review
Biaxial Tensile Test
Biaxial tensile test is a tensile testing in which the sample is stretched in two distinct directions. This technique is used to obtain the mechanical characteristics of anisotropic materials, such as composite materials, textiles, and soft biological tissues. There are three main types of biaxial tensile testing: Bursting test, based on a circular specimen clamped along the edge and inflated by air or water under pressure until the specimen bursts; Cylinder test, based on a hollow cylinder subjected to internal pressure and axial pressure or tension; Plane biaxial test, which offers the best result because of the independent force introduction in the two main directions.
  • 2.1K
  • 28 Oct 2022
Topic Review
Sustainable Supply Chain Practices in the Cement Industry
Sustainable supply chain management (SSCM) is an extension of traditional supply chain management (SCM) that takes into account environmental and social concerns. Cement manufacturing has been recognized as an intensive consumer of natural raw materials, fossil fuels, and energy, as well as a major source of multiple pollutants. This entry attempted to develop a model for SSCM practices by incorporating 23 SSCM factors divided into three dimensions of sustainability: nine factors of environmental SSCM, seven factors of social SSCM, and seven factors of economic SSCM.
  • 2.1K
  • 26 May 2023
Topic Review
Link of Narcissism and Art and Beauty Appreciation
The relationship between narcissistic personality and art and beauty appreciation has become the focus of research investigations. Adaptive narcissists raise their sense of worth in order to shield themselves from harm caused by others. Because they aspire to be more attractive, healthier, and successful versions of themselves, they frequently have greater success in life than the majority of people. Grandiose and overtly narcissistic behavior are the main recognized characteristics of an overt narcissist, which is currently regarded as a personality disorder that puts mental health and wellbeing at peril. 
  • 2.1K
  • 16 Jun 2023
Topic Review
Machine Learning for Crop Disease
Crop diseases constitute a serious issue in agriculture, affecting both quality and quantity of agriculture production. Disease control has been a research object in many scientific and technologic domains. Technological advances in sensors, data storage, computing resources and artificial intelligence have shown enormous potential to control diseases effectively. A growing body of literature recognizes the importance of using data from different types of sensors and machine learning approaches to build models for detection, prediction, analysis, assessment, etc. However, the increasing number and diversity of research studies requires a literature review for further developments and contributions in this area. 
  • 2.1K
  • 24 Nov 2021
Topic Review
Aquilaria Identification Methods and Phytochemicals
Aquilaria sinensis (Lour.) Gilg is the resin-containing wood of the Aquilaria. Agarwood is a traditional Chinese medicine included in the 2020 edition of Chinese Pharmacopoeia.  The main phytochemicals of agarwood include terpenoids, dominated by sesquiterpenes. For centuries, terpenoids have been used in traditional Chinese medicine and have been shown to possess various pharmacological properties, including bacteriostatic, antibacterial, sedation, analgesia, anti-inflammation, anti-asthmatic, hypoglycemic, antidepressant, and many others. Alongside biological activity screening, phytochemical advances and pharmacological research have also made certain progress. 
  • 2.1K
  • 29 Mar 2022
Topic Review
Optical Coherence Angiography Imaging in Ocular Vascular Diseases
Optical coherence tomography angiography (OCTA) provides us with a non-invasive and efficient means of imaging anterior and posterior segment vasculature in the eye. OCTA has been shown to be effective in imaging diseases such as diabetic retinopathy, retinal vein occlusions, retinal artery occlusions, ocular ischemic syndrome and neovascularization of the iris. It is especially useful with depth-resolved imaging of the superficial, intermediate, and deep capillary plexi in the retina, which enables us to study and closely monitor disease progression and response to treatment. With further advances in technology, OCTA has the potential to become a more widely used tool in the clinical setting and may even supersede ocular angiography in some areas.
  • 2.1K
  • 29 Oct 2020
Topic Review
Multi-Microgrid Scheduling
Multi-microgrids address the need for a resilient, sustainable, and cost-effective electricity supply by providing a coordinated operation of individual networks. Due to local generation, dynamic network topologies, and islanding capabilities of hosted microgrids or groups thereof, various new fault mitigation and optimization options emerge. However, with the great flexibility, new challenges such as complex failure modes that need to be considered for a resilient operation, appear. Multi-Microgrid scheduling refers to the procedure of jointly controlling the assets in a multi-microgrid such that the potential of multi-microgrids can be leveraged.
  • 2.1K
  • 26 Oct 2020
Topic Review
Carnitine Acyl-carnitine Carrier
The SLC25A20 transporter, also known as carnitine acyl-carnitine carrier (CAC), catalyzes the transport of short, medium and long carbon chain acyl-carnitines across the mitochondrial inner membrane in exchange for carnitine. The 30-year story of the protein responsible for this function started with its purification from rat liver mitochondria. 
  • 2.1K
  • 07 Apr 2021
Topic Review
Bacterial Biofilms
Bacterial biofilm is a group of cooperative and coordinated unicellular microbes which are associated with physiological and structural complexity, and they are analogous to multicellular microorganisms.
  • 2.1K
  • 04 Jun 2021
Topic Review
Croaker Fishery Exploited from the Bay of Bengal
Croakers, locally called Jewfish or Poa mash, are among the largest groups of commercially important fishes exploited from Bangladesh’s Bay of Bengal (BoB) water. Croakers are under the Perciformes order and belong to the family Sciaenidae.
  • 2.1K
  • 10 Jan 2022
Topic Review
Tau Isoforms
Tau was first described as a natively unfolded microtubule-associated protein. In fact, its main function is to promote the assembly of microtubules and stabilize their structure. However, Tau proteins have a variety of other functions, which include maintaining the structural integrity of neurons, contributing to signal transmission between neurons, and axonal transport. Tau also plays a role in regulating myelination, iron homeostasis, and neurogenesis and may also support synaptic plasticity. Other roles attributed to Tau are gene expression regulation, DNA protection, genome stability, microRNA activity, RNA protection, RNA metabolism, and protein synthesis.
  • 2.1K
  • 27 Dec 2022
Topic Review
Osteoporosis Pathophysiology
Osteoporosis is a major public health concern affecting millions of people worldwide and resulting in significant economic costs. The condition is characterized by changes in bone homeostasis, which lead to reduced bone mass, impaired bone quality, and an increased risk of fractures. The pathophysiology of osteoporosis is complex and multifactorial, involving imbalances in hormones, cytokines, and growth factors. Understanding the cellular and molecular mechanisms underlying osteoporosis is essential for appropriate diagnosis and management of the condition.
  • 2.1K
  • 07 Dec 2023
Topic Review
Distributed Denial of Service (DDoS)
Distributed Denial of Service (DDoS) attack is a major threat impeding service to legitimate requests on any network. Although the first DDoS attack was reported in 1996, the complexity and sophistication of these attacks has been ever increasing. A 2 TBps attack was reported in mid-August 2020 directed towards critical infrastructure, such as finance, amidst the COVID-19 pandemic. It is estimated that these attacks will double, reaching over 15 million, in the next 2 years. A number of mitigation schemes have been designed and developed since its inception but the increasing complexity demands advanced solutions based on emerging technologies. Blockchain has emerged as a promising and viable technology for DDoS mitigation. The inherent and fundamental characteristics of blockchain such as decentralization, internal and external trustless attitude, immutability, integrity, anonymity and verifiability have proven to be strong candidates, in tackling this deadly cyber threat. This survey discusses different approaches for DDoS mitigation using blockchain in varied domains to date. The paper aims at providing a comprehensive review, highlighting all necessary details, strengths, challenges and limitations of different approaches. It is intended to serve as a single platform to understand the mechanics of current approaches to enhance research and development in the DDoS mitigation domain.
  • 2.1K
  • 07 Feb 2021
Topic Review
Psycho-Didactic Approach in Religious and Moral Education
The psycho-didactic approach in education is becoming more and more popular. Its supporters emphasize the great values that are associated with the implementation of this approach to various fields of science and school subjects. The greatest value of the psycho-didactic approach is supporting the personal growth of the learner by respecting the developmental factors involved in each subject’s learning processes. Psycho-didactics could also be used in the design of core curricula and their implementation in the field of religious, ethical, and moral education. By supporting personal development through moral and religious education, it is possible to simultaneously influence the agency of each learner. Personal agency in self-development, as well as in religious and moral development, is one of the greatest challenges for modern education and one of the most significant issues of positive mental health advancement in the field of education. Within psycho-didactics, it becomes possible to foster every student in an individual way, therefore all methods and techniques used in the psycho-didactic approach are focused on the student’s needs.
  • 2.1K
  • 24 Nov 2021
Topic Review
Engineering Microbial Consortia towards Bioremediation
Engineering microbial consortia is an effective way for the removal of heavy metals and organic pollutants. In the study, we discussed the molecular and ecological mechanisms of engineering microbial consortia with a particular focus on metabolic cross-feeding within species and the transfer of metabolites. Besides, the advantages and limitations of top-down and bottom-up approaches of engineering microbial consortia were discussed, together with their applications in bioremediation.
  • 2.1K
  • 29 Oct 2021
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