Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Pilot Findings on SARS-CoV-2 Vaccine-Induced Pituitary Diseases
Since the emergence of the COVID-19 pandemic at the end of 2019, a massive vaccination campaign has been undertaken rapidly and worldwide. Like other vaccines, the COVID-19 vaccine is not devoid of side effects. Typically, the adverse side effects of vaccination include transient headache, fever, and myalgia. Endocrine organs are also affected by adverse effects. The major SARS-CoV-2 vaccine-associated endocrinopathies reported since the beginning of the vaccination campaign are thyroid and pancreas disorders. SARS-CoV-2 vaccine-induced pituitary diseases have become more frequently described in the literature. 
  • 2.5K
  • 08 Dec 2022
Topic Review
Microalgae Bioactive Compounds to Topical Applications Products
Microalgae are complex photosynthetic organisms found in marine and freshwater environments that produce valuable metabolites. Microalgae-derived metabolites have gained remarkable attention in different industrial biotechnological processes and pharmaceutical and cosmetic industries due to their multiple properties, including antioxidant, anti-aging, anti-cancer, phycoimmunomodulatory, anti-inflammatory, and antimicrobial activities. These properties are recognized as promising components for state-of-the-art cosmetics and cosmeceutical formulations.
  • 2.5K
  • 13 Jun 2022
Topic Review
Neurodegeneration in Multiple Sclerosis
Neurodegeneration in multiple sclerosis is believed to underlie disease progression and permanent disability. Many mechanisms of neurodegeneration in MS have been proposed, such as mitochondrial dysfunction, oxidative stress, neuroinflammation, and most recently RNA-binding protein dysfunction. Studying RNA-binding protein dysfunction addresses a gap in our understanding of the pathogenesis of MS, which may allow for novel therapies to be generated to attenuate neurodegeneration before irreversible central nervous system damage occurs.
  • 2.5K
  • 29 Jun 2021
Topic Review
CD19-CAR-T Cells
CD19-targeted chimeric antigen receptor (CAR) T (CD19-CAR-T) cell therapy usually causes B cell aplasia because of “on-target off-tumor” toxicity. The aim of the study was to assess the concept that the introduction of an inhibitory CAR (iCAR) into CAR-T cells could alleviate the side effect of CD19-CAR-T cell therapy. The results showed that CD19-CAR-T cells with a novel KIR/PD-1-based inhibitory CAR (iKP-19-CAR-T) exhibited more naïve, less exhausted phenotypes and preserved a higher proportion of central memory T cells (TCM). Furthermore, iKP-19-CAR-T cells exerted the similar level of cytotoxicity on CD19+HLA-C1- Burkitt’s lymphoma cells compared to CD19-CAR-T cells while sparing CD19+HLA-C1+ healthy human B cells both in vitro and in the xenograft model. Our data demonstrates that the KIR/PD-1-based inhibitory CAR can be a promising strategy to avoid B cell aplasia caused by CD19-CAR-T cell therapy.  
  • 2.5K
  • 26 Oct 2020
Topic Review
Climate Emergency Declarations in Australia
Climate Emergency is being declared in Australia similarly to many other jurisdictions across the world (actions known as Climate emergency declaration). One such jurisdiction in Australia, Darebin City Council, was the first one in the world to declare a climate emergency in 2016. This page lists all known climate emergency declarations within Australian jurisdictions across all three levels of government in Australia (Local, State, and Federal).
  • 2.5K
  • 20 Oct 2022
Topic Review
Bullet Journal
Bullet Journal is a method of personal organization developed by designer Ryder Carroll. The system organizes scheduling, reminders, to-do lists, brainstorming, and other organizational tasks into a single notebook. The name "Bullet Journal" comes from the use of abbreviated bullet points to log information, but it also partially comes from the use of dot journals, which are gridded using dots rather than lines. First shared with the public in 2013, it has become a popular method, garnering significant attention on Kickstarter, Instagram, Facebook, YouTube, and Pinterest.
  • 2.5K
  • 31 Oct 2022
Topic Review
Nitroglycerin (Medication)
Nitroglycerin, also known as glyceryl trinitrate (GTN), is a medication used for heart failure, high blood pressure, anal fissures, painful periods, and to treat and prevent chest pain caused by decreased blood flow to the heart (angina) or due to the recreational use of cocaine. This includes chest pain from a heart attack. It is taken by mouth, under the tongue, applied to the skin, or by injection into a vein. Common side effects include headache and low blood pressure. The low blood pressure can be severe. It is unclear if use in pregnancy is safe for the baby. It should not be used together with medications within the sildenafil (PDE5 inhibitor) family due to the risk of low blood pressure. Nitroglycerin is in the nitrate family of medications. While it is not entirely clear how it works, it is believed to function by dilating blood vessels. Nitroglycerin was written about as early as 1846 and came into medical use in 1878. It is on the World Health Organization's List of Essential Medicines. The drug nitroglycerin (GTN) is a dilute form of the same chemical used as the explosive, nitroglycerin. Dilution makes it non-explosive. In 2019, it was the 184th most commonly prescribed medication in the United States, with more than 3 million prescriptions.
  • 2.5K
  • 01 Nov 2022
Topic Review
Computer Vision and Convolutional Neural Networks
Computer vision (CV) combined with a deep convolutional neural network (CNN) has emerged as a reliable analytical method to effectively characterize and quantify high-throughput phenotyping of different grain crops, including rice, wheat, corn, and soybean. In addition to the ability to rapidly obtain information on plant organs and abiotic stresses, and the ability to segment crops from weeds, such techniques have been used to detect pests and plant diseases and to identify grain varieties. The development of corresponding imaging systems to assess the phenotypic parameters, yield, and quality of crop plants will increase the confidence of stakeholders in grain crop cultivation, thereby bringing technical and economic benefits to advanced agriculture.
  • 2.5K
  • 14 Nov 2022
Topic Review
Centralised Generation
Centralised generation refers the common process of electricity generation through large-scale centralised facilities, through Transmission lines to consumer. These facilities are usually located far away from consumers and distribute the electricity through high voltage transmission lines to a substation where it is then distributed to consumers. The basic concept being that incredibly large stations create electricity for a large group of people. The Vast majority of electricity used in Australia as well as the United States is created from Centralised Generation. Most Centralised Power Generation comes from large power plants run by fossil fuels such as coal or natural gas. Nuclear or large hydroelectricity plants are also commonly used. Many disagree with the processes of Centralised Generation as it often relies on electrical generation through processes of the combustion of fossil fuels, which are bad for the environment. However unsustainable the current system is, it is by far the most widely used, reliable and efficient system that is currently in use. Centralised Generation is fundamentally the opposite of distributed generation. Distributed generation is the small-scale generation of electricity to smaller groups of consumers. This can also include independently producing electricity by either solar or wind power. In recent years Distributed generation as has seen a spark in popularity due to its propensity to use renewable energy generation methods such as wind and solar.
  • 2.5K
  • 23 Nov 2022
Topic Review
Hydraulic Free-Piston Engines
The hydraulic free-piston engine (HFPE) is a kind of hybrid-powered machine which combines the reciprocating piston-type internal combustion engine and the plunger pump as a whole. In recent years, the HFPE has been investigated by a number of research groups worldwide due to its potential advantages of high efficiency, energy savings, reduced emissions and multi-fuel operation.
  • 2.5K
  • 14 Jul 2021
Topic Review
Pyrimidine Derivatives as Anticancer Agents
In this entry, new pyrimidine derivatives were designed, synthesized and analyzed in terms of their anticancer properties. The tested compounds were evaluated in vitro for their antitumor activity. The cytotoxic effect on normal human dermal fibroblasts (NHDF) was also determined. According to the results, all the tested compounds exhibited inhibitory activity on the proliferation of all lines of cancer cells (colon adenocarcinoma (LoVo), resistant colon adenocarcinoma (LoVo/DX), breast cancer (MCF-7), lung cancer (A549), cervical cancer (HeLa), human leukemic lymphoblasts (CCRF-CEM) and human monocytic (THP-1)).
  • 2.5K
  • 23 Apr 2021
Topic Review
Nanomaterials from Industrial, Biological Activities
Nanotechnology and nanoparticles are found to be very effective because of their unique chemical and physical properties and high surface area, but their high cost is one of the major hurdles to its wider application. So, the synthesis of nanomaterials, especially 2D nanomaterials from industrial, agricultural, and other biological activities, could provide a cost-effective technique. The nanomaterials synthesized from such waste not only minimize pollution, but also provide an eco-friendly approach towards the utilization of the waste.
  • 2.5K
  • 23 Jun 2021
Topic Review
Water Quality Monitoring System Using LoRaWAN
For effective process monitoring and enhanced control in wide areas, reliable and accurate real-time measuring is essential. LoRa, a low-power, wide-area network modulation technology (LPWAN), refers to long-range data communications. LoRa allows for long-range communications of up to three miles or five kilometers in urban areas and up to ten miles or 15 km in rural areas. The ultra-low power requirements of LoRa-based systems are a crucial feature, allowing for the design of battery-operated devices that can last up to 10 years. A star network based on the open LoRaWAN protocol is suitable for an implementation scheme that needs long-range or deep in-building communication.
  • 2.5K
  • 29 Jun 2022
Topic Review
APT (Package Manager)
Advanced Package Tool, or APT, is a free-software user interface that works with core libraries to handle the installation and removal of software on Debian, Ubuntu, and related Linux distributions. APT simplifies the process of managing software on Unix-like computer systems by automating the retrieval, configuration and installation of software packages, either from precompiled files or by compiling source code.
  • 2.5K
  • 24 Oct 2022
Topic Review
Chaos (Cosmogony)
Chaos (Ancient Greek:) refers to the void state preceding the creation of the universe or cosmos in the Greek creation myths, or to the initial "gap" created by the original separation of heaven and earth.
  • 2.5K
  • 21 Nov 2022
Topic Review
Energy Recovery in Air Conditioning Systems
Energy has become the backbone of humanities daily activities. Heating, ventilating, and air conditioning systems (HVAC), which consume around 39% of energy in the residential sector, have turned into an essential constituent for providing fresh air, especially after COVD-19, not only in hospitals but also in any simple construction. Thus, decreasing this percentage or recovering part of the energy lost is an essential issue in today’s energy management scenarios.
  • 2.5K
  • 11 Jan 2022
Topic Review
Boiling Water Reactor
A boiling water reactor (BWR) is a type of light water nuclear reactor used for the generation of electrical power. It is the second most common type of electricity-generating nuclear reactor after the pressurized water reactor (PWR), which is also a type of light water nuclear reactor. The main difference between a BWR and PWR is that in a BWR, the reactor core heats water, which turns to steam and then drives a steam turbine. In a PWR, the reactor core heats water, which does not boil. This hot water then exchanges heat with a lower pressure system, which turns water into steam that drives the turbine. The BWR was developed by the Argonne National Laboratory and General Electric (GE) in the mid-1950s. The main present manufacturer is GE Hitachi Nuclear Energy, which specializes in the design and construction of this type of reactor.
  • 2.5K
  • 24 Nov 2022
Topic Review
Visual Values in Landscapes
The term “landscape” can have different meanings depending on the field of study. For a geomorphologist, for example, the landscape represents the Earth’s surface and is considered as the result of the formational physical processes. Meanwhile, a landscape ecologist would consider a landscape in the light of interactions that once took place or now take place within it. The focus on the interaction is equally felt behind the definition of the landscape provided by the European Landscape Convention (ELC), which considers a landscape as “an area, as perceived by people, whose character is the result of the action and interaction of natural and/or human factors”(art. 1). This definition combines three significant aspects of the landscape: its geographical origins, anthropogenic modifications, and human perception. Visual values in landscapes are strictly related to human perception: they exist because they are perceived. 
  • 2.5K
  • 25 Apr 2021
Topic Review
The Oxytocin System in the Brain
Research on oxytocin (OT) was pioneered in the 1920s by German anatomist Ernst Scharrer, after he identified unusual, large-shaped “glandule-like” cells in the hypothalamus of fish. A full anatomical, morphological and functional assessment would follow in the next 50 years, complemented by the Nobel-prize awarded for the synthesis of OT to Vincent du Vigneaud in 1955.
  • 2.5K
  • 09 Dec 2022
Topic Review
LncRNA-Protein Interactions
LncRNA can act as gene regulators, and like other epigenetic mechanisms are involved in numerous biological processes. They achieve their regulatory function with their ability to interact with a wide range of biological molecules, such as other nucleic acids and proteins. These lncRNA-protein interactions (LPI) are involved in many biological pathways including development and disease. A variety of computational LPI predictors exist, each applying different strategies to achieve their goals, and are dependent on a few biological databases containing subsets of experimentally validated LPI. Most modern lncRNA-protein interaction (LPI) prediction algorithms use machine learning approaches, where algorithms are trained on large datasets with attributes of interest.
  • 2.5K
  • 05 Jul 2021
  • Page
  • of
  • 2799
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback