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Topic Review
Membrane Fouling
Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). A major impediment to the improved performance of membrane separation processes, in general, is membrane fouling. Fouling has detrimental effects on the membrane’s performance and integrity, as the deposition and accumulation of foulants on its surface and/or within its pores leads to a decline in the permeate flux, deterioration of selectivity, and permeability, as well as a significantly reduced lifespan. Several factors influence the fouling-propensity of a membrane, such as surface morphology, roughness, hydrophobicity, and material of fabrication. Generally, fouling can be categorized into particulate, organic, inorganic, and biofouling. Efficient prediction techniques and diagnostics are integral for strategizing control, management, and mitigation interventions to minimize the damage of fouling occurrences in the membranes. To improve the antifouling characteristics of RO membranes, surface enhancements by different chemical and physical means have been extensively sought after. Moreover, research efforts have been directed towards synthesizing membranes using novel materials that would improve their antifouling performance. 
  • 2.5K
  • 18 May 2021
Topic Review
Stellar Astronomy
Astronomy (from grc ἀστρονομία (Script error: No such module "Ancient Greek".) 'science that studies the laws of the stars') is a natural science that studies celestial objects and phenomena. It uses mathematics, physics, and chemistry in order to explain their origin and evolution. Objects of interest include planets, moons, stars, nebulae, galaxies, and comets. Relevant phenomena include supernova explosions, gamma ray bursts, quasars, blazars, pulsars, and cosmic microwave background radiation. More generally, astronomy studies everything that originates beyond Earth's atmosphere. Cosmology is a branch of astronomy that studies the universe as a whole. Astronomy is one of the oldest natural sciences. The early civilizations in recorded history made methodical observations of the night sky. These include the Babylonians, Greeks, Indians, Egyptians, Chinese, Maya, and many ancient indigenous peoples of the Americas. In the past, astronomy included disciplines as diverse as astrometry, celestial navigation, observational astronomy, and the making of calendars. Nowadays, professional astronomy is often said to be the same as astrophysics. Professional astronomy is split into observational and theoretical branches. Observational astronomy is focused on acquiring data from observations of astronomical objects. This data is then analyzed using basic principles of physics. Theoretical astronomy is oriented toward the development of computer or analytical models to describe astronomical objects and phenomena. These two fields complement each other. Theoretical astronomy seeks to explain observational results and observations are used to confirm theoretical results. Astronomy is one of the few sciences in which amateurs play an active role. This is especially true for the discovery and observation of transient events. Amateur astronomers have helped with many important discoveries, such as finding new comets.
  • 2.5K
  • 17 Oct 2022
Topic Review
Lazar Armored Vehicle
LAZAR is an 8×8 multi-role military vehicle family produced by the Serbian defence industry company Yugoimport SDPR.
  • 2.5K
  • 16 Nov 2022
Topic Review
Bioactive Compounds from Rice Varieties
Consumption of pigmented rice as a staple food is rapidly increasing due to their healthy prospective and considered as functional food ingredients. Greater interest has been shown in many color rice varieties due to their multiple biological activities. The phenolic compounds have been found to consist of anthocyanidins, ferulic acid, diferulates, anthocyanins and polymeric proanthocyanidins. Anthocyanin is located in the bran layers of the rice kernel, while phenolic acids are mainly present in the bran layers of rice, existing as free, conjugated and bound forms. Keeping in view the several health benefits associated with the functional ingredients, such as anti-inflammatory, antioxidative and anticancer effects, pigmented rice is considered as a functional food and food ingredient in many Asian countries. 
  • 2.5K
  • 10 Jan 2021
Topic Review
Characterization of Semi-Solid Formulations
Specific aspects of semi-solid dosage forms for topical application include the nature of the barrier to be overcome, aspects of susceptibility to physical and chemical instability, and a greater influence of sensory perception. Advances in understanding the driving forces of skin penetration as well as the design principles and inner structure of formulations, provide a good basis for the more rational design of such dosage forms, which still often follow more traditional design approaches. The characterization of semi-solid dosage forms also requires specific approaches. In particular, rheology, chemical stability considering the specifics of semi-solid vehicles, and in vitro performance testing will be discussed.
  • 2.5K
  • 07 Jul 2023
Topic Review
Suicidal Ideation Mechanism
Suicidal ideation mechanism is the psychological process of how thoughts of killing oneself emerge and persist in the mind. From the mindsponge-based suicidal ideation mechanism perspective, there are two conditions for suicidal ideation to happen: (1) the existence of accessible suicide-related information in the environment, and (2) the subjective perception that suicide being a beneficial option. Psychosocial factors (e.g. social connectedness or burdensomeness) can affect these two conditions and, in turn, influence the probability of suicidal ideation.
  • 2.5K
  • 04 Feb 2022
Topic Review
Spicules-Based Topical Delivery Systems
Sponge spicules have recently been utilized as scattered microneedles to disrupt the skin barrier and enhance the skin penetration of a series of therapeutics and even nanoparticles. Spicules can physically disrupt skin in a dose-dependent manner and be retained within the skin over a long time, which provides a convenient, safe, and effective skin delivery strategy.
  • 2.5K
  • 16 Dec 2021
Topic Review
Remote Monitoring of Vital Signs
Techniques for noncontact measurement of vital signs using camera imaging technologies have been attracting increasing attention. For noncontact physiological assessments, computer vision-based methods appear to be an advantageous approach that could be robust, hygienic, reliable, safe, cost effective and suitable for long distance and long-term monitoring. In addition, video techniques allow measurements from multiple individuals opportunistically and simultaneously in groups. This paper aims to explore the progress of the technology from controlled clinical scenarios with fixed monitoring installations and controlled lighting, towards uncontrolled environments, crowds and moving sensor platforms. We focus on the diversity of applications and scenarios being studied in this topic. From this review it emerges that automatic multiple regions of interest (ROIs) selection, removal of noise artefacts caused by both illumination variations and motion artefacts, simultaneous multiple person monitoring, long distance detection, multi-camera fusion and accepted publicly available datasets are topics that still require research to enable the technology to mature into many real-world applications.
  • 2.5K
  • 30 Oct 2020
Topic Review
The Relationship between COVID-19 and Hypothalamic–Pituitary–Adrenal Axis
Coronavirus disease 2019 (COVID-19) is a highly heterogeneous disease regarding severity, vulnerability to infection due to comorbidities, and treatment approaches. The hypothalamic–pituitary–adrenal (HPA) axis has been identified as one of the most critical endocrine targets of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that might significantly impact outcomes after infection.
  • 2.5K
  • 18 Jul 2022
Topic Review
Mitochondrial Heteroplasmy and Disease
Given the relevance of mitochondria in numerous physiological and pathological mechanisms, such as adenosine triphosphate (ATP) synthesis, apoptosis, metabolism, cancer progression, and drug resistance, mitochondrial genome (mtDNA) analysis has become of great interest in the study of human diseases, including cancer. A high number of variants and mutations have been identified in different types of tumors, which coexist with normal alleles, a phenomenon named heteroplasmy. This mechanism is considered an intermediate state between the fixation or elimination of the acquired mutations. It is suggested that mutations, which confer adaptive advantages to tumor growth and invasion, are enriched in malignant cells.
  • 2.5K
  • 09 Sep 2022
Topic Review
Developments in the Diagnosis of Postoperative Crohn’s Disease
Crohn’s disease (CD) is a chronic progressive inflammatory bowel disease leading to bowel damage and disability. The diagnosing recurrence in postoperative Crohn's disease is discussed. 
  • 2.5K
  • 06 Dec 2022
Biography
Heinz Haber
Heinz Haber (May 15, 1913 in Mannheim – February 13, 1990 in Hamburg) was a Germany physicist and science writer who primarily became known for his TV programs and books about physics and environmental subjects. His lucid style of explaining hard science has frequently been imitated by later popular science presenters in Germany. Heinz Haber was born in 1913. His father, Carl Haber, was dir
  • 2.5K
  • 15 Dec 2022
Topic Review
Enterococcus
Enterococci derived from an ancestor that was a commensal of aquatic life forms, when animals first became terrestrial. To cope with the stresses of the new terrestrial habitat, enterococci evolved to be tough bugs, resistant to a wide range of environmental and host factors. That made them extremely successful not only in adapting to the new way of life of their hosts, but also in colonizing other non-animal, and even inanimate, environments - such as feeds and foods. The plasticity of the enterococcal genome, together with their notable ability to trade virulence and antibiotic resistance, have enabled them to also become notable opportunistic, multi-resistant pathogens and act as reservoirs of pathogenicity and resistance determinants.
  • 2.5K
  • 31 Aug 2020
Topic Review
Sustainable Digital Innovation
Digital innovation is referring to a product, process or business model that is new or requires significant changes and it is enabled by IT. Sustainable digital innovation supports the digitalization process of the economy in a green, long-lasting and organic way. Thus, it serves the need of a sustainable future. The regular digital innovation addresses performances, costs, technology and attractiveness to customers and business, while the sustainable one also addresses to the environmental and social factors. Sustainable digital innovation tries to create value for all the stakeholders involved in the production and distribution process, it is inspired by nature, not only by technology, it reduces resources waste and targets the societal goals, not only the commercial and business goals.
  • 2.5K
  • 17 Jun 2021
Topic Review
Chemical Enzymology of Monoamine Oxidase
Monoamine oxidase (E.C. 1.4.3.4) enzymes MAO A and MAO B are FAD-containing proteins located on the outer face of the mitochondrial inner membrane, retained there by hydrophobic interactions and a transmembrane helix. The redox co-factor (FAD) is covalently attached to a cysteine and buried deep inside the protein behind an aromatic cage that aligns substrates towards the flavin. MAO metabolizes neurotransmitters such as dopamine and serotonin in the nervous system so is a target for drugs to modify amine levels. MAO also metabolizes a wide range of biogenic amines in all tissues. Current accumulated evidence, particularly from theoretical modelling, supports hydride transfer as the chemical mechanism. The long active site cavity accommodates a wide chemical variety of small molecules designed as inhibitors, including coumarins, chromones, triazoles, and more. Inactivators that bind covalently to MAO include hydrazines, cyclopropylamines and propargylamines. This entry is an extract adapted from a review outlining the remaining uncertainties in the understanding of this key drug target.
  • 2.5K
  • 19 Oct 2021
Topic Review
Functional Attitude Theory
Functional attitude theory (FAT) suggests that beliefs and attitudes are influential to various psychological functions. Attitudes can be influential on many processes such as being utilitarian (useful), social, relating to values, or a reduction of cognitive dissonance. They can be beneficial and help people interact with the world. In the late 1950s when psychoanalysis and behaviorism reigned supreme as the foci of psychological studies, Smith, Bruner, and White (1956) and Katz (1960) separately and independently developed typologies of human attitudes in relation to the functions to which they believed the attitudes served. This theory proposes that attitudes are held by individuals because they are important and integral to psychological functioning. The function of an attitude is more important than whether the attitude is accurate or correct.
  • 2.5K
  • 20 Oct 2022
Topic Review
Europa Lander (NASA)
The Europa Lander is a proposed astrobiology mission concept by NASA to Europa, an icy moon of Jupiter. If funded and developed as a Flagship mission, it would be launched in 2025 to complement the studies by the Europa Clipper orbiter mission and perform analyses on site. The objectives of the mission are to search for biosignatures at the subsurface ≈10 cm, to characterize the composition of non-ice near-subsurface material, and determine the proximity of liquid water and recently erupted material near the lander's location.
  • 2.5K
  • 28 Oct 2022
Topic Review
Sheela Na Gig
Sheela na gigs are figurative carvings of naked women displaying an exaggerated vulva. They are architectural grotesques found all over Europe on churches, castles, and other buildings. The highest concentrations can be found in Ireland, Great Britain, France and Spain, sometimes together with male figures. Ireland has the greatest number of surviving sheela na gig carvings; McMahon and Roberts cite 101 examples in Ireland and 45 examples in Britain. One of the best examples may be found in the Round Tower at Rattoo, in County Kerry, Ireland. There is a replica of the Round Tower sheela na gig in the County Museum in Tralee town. Another well-known example may be seen at Kilpeck in Herefordshire, England. The carvings may have been used to ward off death and evil. Other grotesques, such as gargoyles and hunky punks, were frequently part of church decorations all over Europe. It is commonly said that their purpose was to keep evil spirits away (see apotropaic magic). They often are positioned over doors or windows, presumably to protect these openings.
  • 2.5K
  • 04 Nov 2022
Topic Review
Virtual Fencing Technology for Cattle Management
Maximizing annual pasture consumption without negatively impacting individual cow performance is of great importance in grass-based dairy and beef systems due to pasture being the most cost-effective nutrient source. However, the disadvantages of conventional and electric fencing include material and labor costs and increased manual labor. Virtual fencing has been developed and evaluated for almost two decades. The evolution of precision livestock farming, specifically virtual fencing, presents new opportunities for maximizing the utilization of available pasture land. Virtual fencing technology decreases the labor involved in physical fencing, provides greater adaptability to changes in pasture conditions, increases precision and efficiency, and offers additional flexibility in grazing management practices. However, that innovative technology should be further developed, and improvements should include decreasing the total costs of the system and increasing its application to other technological groups of ruminants, e.g., suckler cows with calves, increasing the efficiency of the system operation in large areas and a larger number of animals. 
  • 2.5K
  • 27 Feb 2023
Topic Review
Swift Fox
The Swift Fox (Vulpes velox) is a small, elusive canid species native to the grasslands and prairies of North America. Known for its remarkable agility and swift movements, the Swift Fox is aptly named and is one of the fastest running mammals in its habitat. Despite facing historical declines due to habitat loss and persecution, conservation efforts have led to the recovery of Swift Fox populations, highlighting their resilience and importance in North American grassland ecosystems.
  • 2.5K
  • 08 Mar 2024
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