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Topic Review Peer Reviewed
Homeopathy and Psychological Therapies
Homeopathy is a popular, although highly debated, medicinal practice based on the administration of remedies in which active substances are so diluted that no detectable trace of them remains in the final product. This hypothesis paper aims to outline a possible reinterpretation of homeopathy in the light of psychological therapies in order to improve its clinical safety and sustainability. 
  • 2.5K
  • 13 Apr 2022
Topic Review
Metal Oxide Nanoparticles
Metal oxide nanoparticles (NPs) have received a great deal of attention as potential theranostic agents. Despite extensive work on a wide variety of metal oxide NPs, few chemically active metal oxide NPs have received Food and Drug Administration (FDA) clearance. The clinical translation of metal oxide NP activity, which often looks so promising in preclinical studies, has not progressed as rapidly as one might expect. The lack of FDA approval for metal oxide NPs appears to be a consequence of the complex transformation of NP chemistry as any given NP passes through multiple extra- and intracellular environments and interacts with a variety of proteins and transport processes that may degrade or transform the chemical properties of the metal oxide NP. Moreover, the translational models frequently used to study these materials do not represent the final therapeutic environment well, and studies in reduced preparations have, all too frequently, predicted fundamentally different physico-chemical properties from the biological activity observed in intact organisms. Understanding the evolving pharmacology of metal oxide NPs as they interact with biological systems is critical to establish translational test systems that effectively predict future theranostic activity. 
  • 2.5K
  • 20 Apr 2021
Topic Review
Career Plateau
Career plateau is a situation in which an employee has less to no possibility of a vertical promotion or a horizontal movement. Ze can feel to be stuck in your current position without room to develop.
  • 2.5K
  • 20 Apr 2022
Topic Review
Mitochondrial Heteroplasmy and Disease
Given the relevance of mitochondria in numerous physiological and pathological mechanisms, such as adenosine triphosphate (ATP) synthesis, apoptosis, metabolism, cancer progression, and drug resistance, mitochondrial genome (mtDNA) analysis has become of great interest in the study of human diseases, including cancer. A high number of variants and mutations have been identified in different types of tumors, which coexist with normal alleles, a phenomenon named heteroplasmy. This mechanism is considered an intermediate state between the fixation or elimination of the acquired mutations. It is suggested that mutations, which confer adaptive advantages to tumor growth and invasion, are enriched in malignant cells.
  • 2.5K
  • 09 Sep 2022
Topic Review
Social Engineering (Security)
In the context of information security, social engineering is the psychological manipulation of people into performing actions or divulging confidential information. This differs from social engineering within the social sciences, which does not concern the divulging of confidential information. A type of confidence trick for the purpose of information gathering, fraud, or system access, it differs from a traditional "con" in that it is often one of many steps in a more complex fraud scheme. It has also been defined as "any act that influences a person to take an action that may or may not be in their best interests." An example of social engineering is the use of the "forgot password" function on most websites which require login. An improperly-secured password-recovery system can be used to grant a malicious attacker full access to a user's account, while the original user will lose access to the account.
  • 2.5K
  • 08 Nov 2022
Topic Review
Electric Vehicle Batteries Reuse
It is a fact that electric vehicles (EVs) are beneficial for climate protection. However, the current challenge is to decide on whether to reuse an EV battery or to recycle it after its first use. The concept of reusing (second life) of the battery is promising because, at the end of the first life, batteries from EVs can be used in several applications such as storing energy generated from renewable sources to support the government grid. 
  • 2.5K
  • 23 Apr 2021
Topic Review
Metal Organic Frameworks
Metal–organic frameworks (MOFs) are a family of porous crystalline materials that serve in some cases as versatile platforms for catalysis. 
  • 2.5K
  • 13 Dec 2021
Topic Review
Chaos (Cosmogony)
Chaos (Ancient Greek:) refers to the void state preceding the creation of the universe or cosmos in the Greek creation myths, or to the initial "gap" created by the original separation of heaven and earth.
  • 2.5K
  • 21 Nov 2022
Topic Review
Advancements of Rim-Driven Fans in Aerial Vehicles
As the aviation industry seeks sustainable propulsion solutions, innovative technologies have emerged, among which rim-driven fan (RDF) systems hold notable promise. Amid escalating concerns about greenhouse gas emissions, the aviation sector’s shift towards electric propulsion has gained impetus. RDF technology has emerged as a beacon of optimism, heralding the prospect of energy-efficient and eco-conscious air travel. 
  • 2.5K
  • 22 Dec 2023
Topic Review
Wheat Blast and Food Security
Wheat blast is a fearsome fungal disease caused by a filamentous fungus, Magnaporthe oryzae Triticum pathotype. It was first detected in Brazil in 1985, then it spread to some neighboring South American countries such as Bolivia, Argentina and Paraguay. The outbreak of wheat blast was spotted in Bangladesh for the first time in 2016, which devastated 15,000 hectares of wheat with yield losses up to 100%. Recently, it was detected in Zambia (an African country). The disease spreads through seeds and airborne conidia. There is no resistant variety against wheat blast disease. Once the disease symptoms are expressed as the bleached or partially bleached spikes, fungicide application is ineffective to control it. A convenient and rapid molecular diagnostic tool is developed for surveillance and monitoring of the wheat blast. However, our understanding the biology of wheat blast fungus and its interactions with the host plant is limited. A globally concerted effort is needed to develop durable blast-resistant varieties to combat this killer of wheat before the spread to major wheat growing countries in the world.
  • 2.5K
  • 23 Oct 2020
Topic Review
Framework of Smart Water System
Throughout the past years, governments, industries, and researchers have shown increasing interest in incorporating smart techniques, including sensor monitoring, real-time data transmitting, and real-time controlling into urban water systems. However, the design and construction of such a smart water system are still not quite standardized for practical applications due to the lack of consensus on the framework. The major challenge impeding the wide application of the smart water network is the unavailability of a systematic framework to guide real-world design and deployment. A new and comprehensive smart water framework, including definition and architecture, was proposed in this article. Two conceptual metrics (smartness and cyber wellness) were defined to evaluate the performance of smart water systems. This work calls for broader collaborations in the community of researchers, engineers, and industrial and governmental sectors to promote smart water applications for addressing the increasing water quantity and quality challenges.
  • 2.5K
  • 03 Feb 2022
Topic Review
Senotherapy
During aging, many biological processes are altered, which globally induce the dysfunction of the whole organism. Cell senescence is one of the causes of this modification. Nowadays, several drugs approved for anticancer therapy have been repurposed to treat senescence, and others are under scrutiny in vitro and in vivo. In particular, molecules named “senomorphics” have been used to prevent or to slow down aging; meanwhile ,those that have been recently identified to induce apoptosis in senescent cells, reducing their number, are called "senolytics”
  • 2.5K
  • 17 Nov 2020
Topic Review
Olive Mill Wastewater Remediation
Olive oil production in Mediterranean countries represents a crucial market, especially for Spain, Italy, and Greece. Waste generated from olive oil production processes can be divided into solid waste and olive mill wastewaters (OMWW). 
  • 2.5K
  • 31 Aug 2022
Topic Review
Mindfulness and Technology
Mindfulness and technology is a movement in research and design, that encourages the user to become aware of the present moment, rather than losing oneself in a technological device. This field encompasses multidisciplinary participation between design, psychology, computer science, and religion. Mindfulness stems from Buddhist meditation practices and refers to the awareness that arises through paying attention on purpose in the present moment, and in a non-judgmental mindset. In the field of Human-Computer Interaction, research is being done on Techno-spirituality — the study of how technology can facilitate feelings of awe, wonder, transcendence, and mindfulness and on Slow design, which facilitates self-reflection. The excessive use of personal devices, such as smartphones and laptops, can lead to the deterioration of mental and physical health. This area focuses on redesigning and creating technology to improve the wellbeing of its users.
  • 2.5K
  • 28 Sep 2022
Topic Review
Universal Priesthood
The universal priesthood or the priesthood of all believers is a principle in some branches of Christianity which abrogates the doctrine of holy orders found in some other branches, including the Roman Catholic and Eastern Orthodox. Derived from the Bible and elaborated in the theology of Martin Luther and John Calvin, the principle became prominent as a tenet of Protestant Christian doctrine, though the exact meaning of the belief and its implications vary widely among denominations.
  • 2.5K
  • 11 Nov 2022
Topic Review
System 1 vs. System 2 Thinking
While the majority of cognitive psychologists now embrace the dual-processing theory of the mind, Systems 1 and 2, there are still some who disagree. Most evolutionary psychologists, in contrast, dispute the existence of System 2, a domain-general mind, although some disagree. However, a consensus is growing in favor of System 2, although evolutionary psychologists’ concerns must be addressed.
  • 2.5K
  • 13 Oct 2023
Topic Review
New Insights into Melanocytes Beyond Conventional Recognition
Melanocytes produce melanin to protect the skin from UV-B radiation. Notwithstanding, the spectrum of their functions extends far beyond their well-known role as melanin production factories. Melanocytes have been considered as sensory and computational cells. The neurotransmitters, neuropeptides, and other hormones produced by melanocytes make them part of the skin’s well-orchestrated and complex neuroendocrine network, counteracting environmental stressors. Melanocytes can also actively mediate the epidermal immune response. Melanocytes are equipped with ectopic sensory systems similar to the eye and nose and can sense light and odor.In addition, melanocytes have also been shown to be localized in internal sites such as the inner ear, brain, and heart, locations not stimulated by sunlight.
  • 2.5K
  • 18 Jul 2022
Topic Review
Croatian National Theater
The National Theater of Zagreb is considered to be the oldest and most important cultural center in Croatia due to its three activities: opera, theater, and ballet. The artistic production is so fruitful; an average of 220 shows are performed in a season. Because of its national influence over a wide territory, the National Theater of Zagreb is used to promote a seasonal program which is broadly varied, including the performance of local artists representative of different styles and historical periods. Nonetheless, the recitals of classic and contemporary masterpieces attract the biggest audiences.
  • 2.5K
  • 13 Jul 2022
Topic Review
Xenograft Model in Animal Models of Cancer
Animal models of cancer may be classified in a variety of ways. Most simply, they are either spontaneous or induced and mammalian or non-mammalian. Alternatively, they may be categorized by the method of inducing cancer occurrence. A xenograft model involves the transplantation of cancer cells from one species (e.g., human) into a host animal of a different species (e.g., mouse).
  • 2.5K
  • 18 Oct 2022
Topic Review
Intestinal Mucus
Overlying gastrointestinal epithelial cells is the transparent mucus layer that separates the lumen from the host. The dynamic mucus layer serves to lubricate the mucosal surface, to protect under-lying epithelial cells, and as a transport medium between luminal contents and epithelial cells. Furthermore, it provides a habitat for commensal bacteria and signals to the underlying immune system. Mucins are highly glycosylated proteins, and their glycocode is tissue-specific and closely linked to the resident microbiota. 
  • 2.5K
  • 19 Feb 2021
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