Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Atlantic Council
The Atlantic Council is an United States Atlanticist think tank in the field of international affairs, founded in 1961. It manages ten regional centers and functional programs related to international security and global economic prosperity. It is headquartered in Washington, D.C.. It is a member of the Atlantic Treaty Association.
  • 2.7K
  • 24 Nov 2022
Topic Review
Circulating Tumors Cells in Metastasis
Tumor-related death is primarily caused by metastasis; consequently, understanding, preventing, and treating metastasis is essential to improving clinical outcomes. Metastasis is mainly governed by the dissemination of tumor cells in the systemic circulation: so-called circulating tumor cells (CTCs). CTCs typically arise from epithelial tumor cells that undergo epithelial-to-mesenchymal transition (EMT), resulting in the loss of cell–cell adhesions and polarity, and the reorganization of the cytoskeleton.
  • 2.7K
  • 25 Nov 2022
Topic Review
Basic Components of Osmotic Pump Systems
Novel drug delivery systems (NDDS) is a broad term that encompasses many dosage forms, one of which is osmotic pumps. Osmotic pumps are considered to be the most reliable source of controlled drug delivery, both in humans and in animals. These pumps are osmotically controlled and release active agents through osmotic pressure. To a large extent, drug release from such a system is independent of gastric fluids. Based on such unique properties and advantages, osmotic pumps have made their mark on the pharmaceutical industry. 
  • 2.7K
  • 07 Dec 2022
Topic Review
Beneficial effects of Glycine in the Organism
Glycine is an amino acid that our bodies can produce naturally, so we don't necessarily need to get it from our diet. Nevertheless, it plays a vital role in various functions throughout our entire body. Glycine interacts with specific receptors and transporters found in many different types of cells, which allows it to have important effects on our health. One of the most fascinating things about glycine is its potential to reduce inflammation in our body. Researchers have conducted many studies focusing on this aspect. Glycine has been shown to decrease pro-inflammatory molecules called cytokines, which are responsible for promoting inflammation. Additionally, it can lower the levels of free fatty acids, which are sometimes linked to inflammation in certain situations. Moreover, glycine seems to positively influence how our body responds to insulin, which is crucial for maintaining stable blood sugar levels. It also appears to bring about other beneficial changes in our body, although scientists are still investigating the specific details of these effects. Glycine is a remarkable amino acid that offers many health benefits, especially in terms of reducing inflammation and possibly enhancing how our bodies respond to insulin. It's fascinating because it is present throughout our entire body, and we can obtain it through our diet or nutraceuticals, affecting our health in various ways. Scientists continue to study glycine to unlock its full potential and better understand its role in supporting our well-being.
  • 2.7K
  • 26 Jul 2023
Topic Review
Bioremediation
Bioremediation can reduce pesticide contamination of agricultural soils by biodegradation processes via the metabolic activities of microorganisms. It is an efficient, cost-effective, and environment-friendly treatment.
  • 2.7K
  • 14 Jul 2021
Topic Review
Fundamentals of Water-Splitting Reaction
A viable energy source, hydrogen has the advantages of clean energy, high conversion efficiency, and environmental friendliness. One of the possible routes for the generation of hydrogen in this context is the solar water splitting reaction under direct sunlight. To succeed on a commercial basis, though, there remains a very long way to go. 
  • 2.7K
  • 07 Nov 2022
Topic Review
Biological Activities of Thiophenes
Thiophenes represent a small family of natural metabolites featured by one to five thiophene rings. Numerous plant species belonging to the family Asteraceae commonly produce thiophenes. These metabolites possessed remarkable bioactivities, including antimicrobial, antiviral, anti-inflammatory, larvicidal, antioxidant, insecticidal, cytotoxic, and nematicidal properties.
  • 2.7K
  • 16 Jan 2024
Topic Review
Understanding Pet Food Attribute Preferences of US Consumers
This encyclopedia entry is dedicated to pet food attributes and builds on the work of Meike Rombach and David Dean. Partial least squares structural equation modelling shows that pet food purchase involvement positively impacts subjective and objective knowledge about pet food. Subjective knowledge appears to be the strongest factor impacting the importance consumers place on all three attributes. This is followed by objective knowledge. Socio-demographic factors such as gender, age, income, and education appear to have a limited impact as predictors for the importance consumers place on the product attributes.
  • 2.7K
  • 17 Jan 2022
Topic Review
In-Vehicle Intrusion Detection Systems
Breaches in the cyberspace due to cyber-physical attacks can harm the physical space, and any type of vehicle is an alluring target for wrongdoers for an assortment of reasons. Especially, as the automobiles are becoming increasingly interconnected within the Cooperative Intelligent Transport System (C-ITS) realm and their level of automation elevates, the risk for cyberattacks augments along with the attack surface, thus inexorably rendering the risk of complacency and inaction sizable. Next to other defensive measures, intrusion detection systems (IDS) already comprise an inextricable component of modern automobiles in charge of detecting intrusions in the system while in operation.
  • 2.7K
  • 07 May 2022
Topic Review
Mars Oxygen ISRU Experiment
The Mars Oxygen In-Situ Resource Utilization Experiment (MOXIE) is a technology demonstration on the NASA Mars 2020 rover Perseverance investigating the production of oxygen on Mars. On April 20, 2021, MOXIE produced oxygen from carbon dioxide in the Martian atmosphere by using solid oxide electrolysis. This was the first experimental extraction of a natural resource from another planet for human use. The technology may be scaled up for use in a human mission to the planet to provide breathable oxygen, oxidizer, and propellant; water may also be produced by combining the produced oxygen with hydrogen. The experiment was a collaboration between the Massachusetts Institute of Technology, the Haystack Observatory, the NASA/Caltech Jet Propulsion Laboratory, and other institutions.
  • 2.7K
  • 28 Nov 2022
Topic Review
Mass Spectrometry-Based Single Cell Analysis
Cell-to-cell variation exists within a population of the same cell type due to stochastic gene and protein expression and environmental factors. Studying such cellular heterogeneity is the key to understanding the underlying mechanisms of fundamental biology and complex diseases, highly demanding developments in advanced technologies for molecular profiling at the single-cell level.
  • 2.7K
  • 14 Mar 2023
Topic Review
Aircraft Noise
Aircraft noise is noise pollution produced by aircraft during the various phases of a flight. Sound production is divided into three categories: Health consequences include sleep disturbance, hearing impairment and heart disease, as well as workplace accidents caused by stress. Memory and recall can also be affected. Governments have enacted extensive controls that apply to aircraft designers, manufacturers, and operators, resulting in improved procedures and cuts in pollution.
  • 2.7K
  • 26 Oct 2022
Topic Review
TIG-MIG Hybrid Welding
Tungsten inert gas-metal inert gas hybrid welding (TIG-MIG) combines the advantages of tungsten and metal inert gas welding. It can efficiently produce high-quality weld joints that meet modern manufacturing quality and efficiency requirements. Based on heat transfer, fluid dynamics, and electromagnetic theory, a three-dimensional coupled transient model of arc-droplet interactions in TIG-MIG hybrid welding was established. In this study, the temperature field, flow field, electromagnetic force, pressure, and current density parameters were analyzed in the arc space. The results show that introducing TIG welding has a significant impact on MIG welding.
  • 2.7K
  • 13 Jan 2021
Topic Review
Secretion Systems of Acinetobacter baumannii
Infections led by Acinetobacter baumannii strains are of great concern in healthcare environments due to the strong ability of the bacteria to spread through different apparatuses and develop drug resistance. Secretion systems have recently been demonstrated to be involved in the pathogenic process, and five types of secretion systems out of the known six from Gram-negative bacteria have been found in A. baumannii. They can promote the fitness and pathogenesis of the bacteria by releasing a variety of effectors. Additionally, antibiotic resistance is found to be related to some types of secretion systems.
  • 2.7K
  • 02 Feb 2023
Topic Review
Gangliosides and Ganglioside GD3-Binding Proteins
Ganglioside GD3 is a major ganglioside in neuronal progenitor cells. Highly sialylated gangliosides, GM1, GD1a, GD1b, GT1b are the main gangliosides in adult neurons. GD3 is implicated in cell attachment and cell-to-cell interaction during embryogenesis. Anti-ganglioside GD3 monoclonal antibody (clone:R24) coimmunoprecipitates heterotrimeric G protein Goα, GPI-anchored neuronal cell adhesion molecule TAG-1, Src-family kinase Lyn and Csk -binding protein Cbp from rat cerebellar granule cells. Ganglioside GD3 is involved in the migration of granule cells during the early stage of cerebellar development via these GD3-binding proteins.
  • 2.7K
  • 03 Apr 2023
Topic Review
YAP/TAZ Activation in Head and Neck Cancer
The Hippo signaling pathway, originally discovered as a mechanism regulating tissue growth and organ size, transduces intracellular and extracellular signals to regulate the transcriptional co-activators YAP and TAZ. Alterations in the Hippo pathway resulting in persistent YAP and TAZ activation have emerged as major oncogenic drivers. The researchers' analysis of the human Head and neck squamous cell carcinoma (HNSCC) oncogenome revealed multiple genomic alterations impairing Hippo signaling and activating YAP and TAZ, which in turn contribute to HNSCC development. This includes mutations and deletions of the FAT1 gene (29%) and amplification of the WWTR1 (encoding TAZ, 14%) and YAP1 genes (8%), together representing one of the most genetically altered signaling mechanisms in this malignancy. 
  • 2.7K
  • 11 May 2022
Topic Review
Testis-Determining Factor
An Error has occurred retrieving Wikidata item for infobox Testis-determining factor (TDF), also known as sex-determining region Y (SRY) protein, is a DNA-binding protein (also known as gene-regulatory protein/transcription factor) encoded by the SRY gene that is responsible for the initiation of male sex determination in therian mammals (placental mammals and marsupials). SRY is an intronless sex-determining gene on the Y chromosome. Mutations in this gene lead to a range of disorders of sex development (DSD) with varying effects on an individual's phenotype and genotype. TDF is a member of the SOX (SRY-like box) gene family of DNA-binding proteins. When complexed with the SF1 protein, TDF acts as a transcription factor that causes upregulation of other transcription factors, most importantly SOX9. Its expression causes the development of primary sex cords, which later develop into seminiferous tubules. These cords form in the central part of the yet-undifferentiated gonad, turning it into a testis. The now-induced Leydig cells of the testis then start secreting testosterone, while the Sertoli cells produce anti-Müllerian hormone. SRY gene effects normally take place 6–8 weeks after fetus formation which inhibits the female anatomical structural growth in males. It also works towards developing the dominant male characteristics.
  • 2.7K
  • 25 Oct 2022
Topic Review
Snap
Snap is a software packaging and deployment system developed by Canonical for operating systems that use the Linux kernel and the systemd init system. The packages, called snaps, and the tool for using them, snapd, work across a range of Linux distributions and allow upstream software developers to distribute their applications directly to users. Snaps are self-contained applications running in a sandbox with mediated access to the host system. Snap was originally released for cloud applications but was later ported to also work for Internet of Things devices and desktop applications.
  • 2.7K
  • 21 Oct 2022
Topic Review
Internationalized Country Code Top-Level Domain
An internationalized country code top-level domain is a top-level domain in the Domain Name System (DNS) of the Internet. IDN ccTLDs are specially encoded domain names that are displayed in an end user application, such as a web browser, in their language-native script or alphabet, such as the Arabic alphabet, or a non-alphabetic writing system, such as Chinese characters. IDN ccTLDs are an application of the internationalized domain name system to top-level Internet domains assigned to countries, or independent geographic regions. Although the domain class uses the term code, some of these ccTLDs are not codes but full words. For example, السعودية (as-Suʻūdiyya) is not an abbreviation of "Saudi Arabia", but the common short-form name of the country in Arabic. Countries with internationalized ccTLDs also retain their traditional ASCII-based ccTLDs. As of August 2018 there are 59 approved internationalized country code top-level domains, of them at least 47 used. The most used are .рф (Russia) with over 900,000 domains names, .台灣 (Taiwan) with around 500,000 and .中国 (China) with over 200,000 domains. Still as of 2018 around 20 countries using non-Latin script do not have an internationalized country code top-level domain, including Japan .
  • 2.7K
  • 10 Nov 2022
Topic Review
Value
In social sciences, value refers to a deeply held belief or principle that guides individuals' attitudes, behaviors, and decision-making processes. Values are subjective and culturally influenced, reflecting what individuals consider important, desirable, or morally significant in their lives and interactions with others. They serve as guiding principles that shape social norms, institutions, and collective identities within society.
  • 2.7K
  • 02 Feb 2024
  • Page
  • of
  • 2727
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback