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Topic Review
Hydroxytyrosol and Oleuropein in Aging and Related Disorders
Aging is a multi-faceted process caused by the accumulation of cellular damage over time, associated with a gradual reduction of physiological activities in cells and organs. This degeneration results in a reduced ability to adapt to homeostasis perturbations and an increased incidence of illnesses such as cognitive decline, neurodegenerative and cardiovascular diseases, cancer, diabetes, and skeletal muscle pathologies. Key features of aging include a chronic low-grade inflammation state and a decrease of the autophagic process. The Mediterranean diet has been associated with longevity and ability to counteract the onset of age-related disorders. Extra virgin olive oil, a fundamental component of this diet, contains bioactive polyphenolic compounds as hydroxytyrosol (HTyr) and oleuropein (OLE), known for their antioxidant, anti-inflammatory, and neuroprotective properties.
  • 2.8K
  • 24 Apr 2023
Topic Review
Mentha piperita
Mentha species are famous as therapeutic herbs and have long served as natural herbal formulations. Mentha piperita L. (peppermint) is regarded as one of the best potential sources of biologically active substances for the food, cosmetics, and pharmaceutical industries. M. piperita, a hybrid mint, is a cross-species between watermint (Mentha aquatica L.) and spearmint (Mentha spicata L.). Other Mentha species are also cultivated around the world for essential oil production.
  • 2.8K
  • 27 Nov 2023
Topic Review
Antimicrobial photodynamic therapy (aPDT)
Photodynamic inactivation is known as a new antimicrobial photodynamic therapy (aPDT). It is based on the administration of a photosensitizer located in the bacterial/viral cell followed by exposure to light radiations (with a proper wavelength corresponding with the maximum value of absorption of the photosensitizer) that generate singlet oxygen or reactive oxygen species, which lead to the death of different microorganisms. This review will present an overview beyond the state-of-the-art of the photosensitizer types (based on tetra-p-sulphonated-phenyl porphyrin—TSPP, which is able to form cationic and J-aggregates forms at different pH values ((1–4) and concentrations around 10−5 M) and their applications of PDT for viruses, especially. 
  • 2.8K
  • 30 Sep 2021
Topic Review
Leaf Senescence
Leaf senescence is an ordered physiological process in which cellular structures and biomolecules are progressively broken down and the resulting products mobilized to other plant organs such as fruits, seeds, tubers and/or more apical leaves.
  • 2.8K
  • 02 Apr 2022
Topic Review
Media Pluralism
Media pluralism defines the state of having a plurality of voices, opinions and analyses on media system (internal pluralism) or the coexistence of different and diverse types of medias and media support (external pluralism). Media pluralism is often recognized by international organizations and non-governmental organizations as being an essential part of a democratic state, Reporters Without Borders considers "access to a plurality of editorial lines and analyses [as] essential for citizens to be able to confront ideas, to make their own informed choices and to conduct their life freely". Expanded access to the Internet and the digital switch-over has enabled an increased availability of media content, largely through sharing and user-generated content on social media, in addition to the digital channels to which individuals have access across television and radio. The diversity of content is however accompanied by what Hallin and Mancini call polarized pluralism in a media system. According to the World Trends Report, a sharper division in the way we use news is coming up due to the interaction between consumption habits, changing economic models and technical systems. This signifies that even if multiple kinds of information and programming are available, each segmented group may only ingest one branch of the whole. The increase of Internet penetration and reliance on online sources for news is thought of to producing siloed debates. At the infrastructural level, ‘zero rating’— in which Internet or mobile service providers allow users to access specific content or applications without counting towards the user’s data ‘cap’— expands in parallel to mobile uptakes, particularly in emerging countries. Traditional business models for the news media continue to be disrupted, leading to vertical and horizontal concentration and introduction of new types of ownership. Challenges to media funding introduce new types of economic models such as pay-walls and crowd-funding initiatives. Gender is a part of media pluralism and is characterized by the under-representation of women in the media workforce, in decision-making and in media content. People with disabilities are also under-represented in the media system.
  • 2.8K
  • 09 Oct 2022
Topic Review
1769 Transit of Venus Observed from Tahiti
On June 3, 1769, British navigator Captain James Cook, British naturalist Joseph Banks, British astronomer Charles Green and Swedish naturalist Daniel Solander recorded the transit of Venus on the island of Tahiti during Cook's first voyage around the world. During a transit, Venus appears as a small black disc travelling across the Sun. This unusual astronomical phenomenon takes place in a pattern that repeats itself every 243 years. It includes two transits that are eight years apart, separated by breaks of 121.5 and 105.5 years. These men, along with a crew of scientists, were commissioned by the Royal Society of London for the primary purpose of viewing the transit of Venus. Not only would their findings help expand scientific knowledge, it would help with navigation by accurately calculating the observer's longitude. At this time, longitude was difficult to determine and not always precise. A "secret" mission that followed the transit included the exploration of the South Pacific to find the legendary Terra Australis Incognita or "unknown land of the South."
  • 2.8K
  • 30 Sep 2022
Topic Review
Theosophy and Politics
Modern Theosophy and politics, according to the statements of Helena Blavatsky and Henry Olcott, are not connected between themselves in any way.(Blavatsky, 1879) However, investigations of historians and religious studies scholars show that the Theosophical movement has played a significant role in consolidation of Indian nationalism. Similar to neo-Hinduism, Theosophy had supporting promotion the nationalist ideology, and this gave Prof. Mark Bevir a reason to consider it not only as a form of "political movement", but also as an "integral part" of neo-Hinduism.
  • 2.8K
  • 02 Dec 2022
Topic Review
Digital Village Implementations
Digital village is a social entity concept formed by community awareness, and a desire to think beyond and build a new form of cooperation and alliances using advanced digital technologies. It is not only incorporating digitalization into the village, but also forming a social entity that can address the problems existing within the village.
  • 2.8K
  • 17 May 2023
Topic Review
Social Mobility
Social mobility refers to the movement of individuals or groups within a social hierarchy, typically involving changes in socioeconomic status, occupational attainment, or educational attainment across generations or within a single lifetime. It encompasses upward mobility, where individuals ascend to higher social positions, as well as downward mobility, where individuals experience a decline in social status. Social mobility reflects the fluidity and dynamism of social structures, influenced by factors such as meritocracy, education, economic opportunity, and social policies.
  • 2.8K
  • 26 Jan 2024
Topic Review
Factors Affecting Quality in Construction
Achieving a high level of quality in a residential building, characterized by the highest level of performance features, is crucial for the client and all participants in the investment process. The identification of negative factors that occur in the investment process, and the assessment of their impact on the quality of the facility, provide important knowledge that gives the basis for controlling the course of the process.
  • 2.8K
  • 17 Feb 2024
Topic Review
Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers
Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs, increase their bioavailability, and extend the residence time in the body, combining low toxicity with a targeted delivery. Nanostructured lipid carriers are the second generation of lipid nanoparticles differing from solid lipid nanoparticles in their composition matrix. The use of a liquid lipid together with a solid lipid in nanostructured lipid carrier allows it to load a higher amount of drug, enhance drug release properties, and increase its stability. Therefore, a direct comparison between solid lipid nanoparticles and nanostructured lipid carriers is needed. 
  • 2.8K
  • 30 May 2023
Topic Review
Historic Gardens Heritage
Historic Garden is a category of historic heritage enshrined in the Florence Charter as a Living Monument (ICOMOS, 1982). They belong to the category of landscape designed and created intentionally by Man (UNESCO, 2021). As the expression of the relationship between Man and nature (ICOMOS, 1982; Kimber, 2004), gardens are part of the cultural landscape of any civilization and society and reflect the culture, identity and history of a people (Añón, 1993; Kimber, 2004). As such, constitutes cultural, artistic and historical documents (Doolitle, 2004) and horticultural compositions (ICOMOS, 1982) of great importance and interest. Since it is composed of living plant material, a garden is a dynamic and constantly changing environment where different types of time (ecological, social and subjective) are brought together and interact (Bhatti et al., 2009). A garden therefore becomes an unfinished work (Estadão, 2005) and one that is necessarily ephemeral (Gollwitzer, 1993). This dynamic transformation leads Sales (1993) to say that a garden is not an object, but rather a process undergoing constant development and decomposition.
  • 2.8K
  • 26 May 2022
Topic Review
Spix's Macaw
Spix's macaw (Cyanopsitta spixii), also known as the little blue macaw, is a macaw native to Brazil. It is a member of tribe Arini in the subfamily Arinae (Neotropical parrots), part of the family Psittacidae (the true parrots). It was first described by German naturalist Georg Marcgrave, when he was working in the State of Pernambuco, Brazil in 1638 and it is named for German naturalist Johann Baptist von Spix, who collected a specimen in 1819 on the bank of the Rio São Francisco in northeast Bahia in Brazil. The bird is a medium-size parrot weighing about 300 grams (11 oz), smaller than most of the large macaws. Its plumage is various shades of blue, with a grey-blue head, light blue underparts, and vivid blue upperparts. Males and females are almost identical in appearance, however the females are slightly smaller on average. Currently there are no known survivors of the species outside of captivity. The species inhabited riparian Caraibeira (Tabebuia aurea) woodland galleries in the drainage basin of the Rio São Francisco within the Caatinga dry forest climate of interior northeastern Brazil. It had a very restricted natural habitat due to its dependence on the tree for nesting, feeding and roosting. It feeds primarily on seeds and nuts of Caraiba and various Euphorbiaceae (spurge) shrubs, the dominant vegetation of the Caatinga. Due to deforestation in its limited range and specialized habitat, the bird has been rare in the wild throughout the twentieth century. It has always been very rare in captivity, partly due to the remoteness of its natural range. The IUCN regard the Spix's macaw as extinct in the wild. Its last known stronghold in the wild was in northeastern Bahia, Brazil and sightings are very rare. After a 2000 sighting of a male bird, the next and last sighting was in 2016. The species is now maintained through a captive breeding program at several conservation organizations under the aegis of the Brazilian government. It is listed on CITES Appendix I, which makes trade illegal except for legitimate conservation, scientific or educational purposes. The Brazilian Chico Mendes Institute for Biodiversity Conservation (ICMBio) is conducting a project Ararinha-Azul with an associated plan to restore the species to the wild as soon as sufficient breeding birds and restored habitat are available.
  • 2.8K
  • 03 Nov 2022
Topic Review
Satellites Spectral Information and Soil Organic Carbon
There is a need to update soil maps and monitor soil organic carbon (SOC) in the upper horizons or plough layer for enabling decision support and land management, while complying with several policies, especially those favoring soil carbon storage. A number of satellite-based spectral approaches for SOC assessment have been achieved from several satellite sensors, study scales and geographical contexts in the past decade.
  • 2.8K
  • 28 Jun 2022
Topic Review
Cross-Cultural Psychology
Cross-cultural psychology is the scientific study of human behavior and mental processes, including both their variability and invariance, under diverse cultural conditions. Through expanding research methodologies to recognize cultural variance in behavior, language, and meaning it seeks to extend and develop psychology. Since psychology as an academic discipline was developed largely in North America and Europe, some psychologists became concerned that constructs accepted as universal were not as invariant as previously assumed, especially since many attempts to replicate notable experiments in other cultures had varying success. Since there are questions as to whether theories dealing with central themes, such as affect, cognition, conceptions of the self, and issues such as psychopathology, anxiety, and depression, may lack external validity when "exported" to other cultural contexts, cross-cultural psychology re-examines them using methodologies designed to factor in cultural differences so as to account for cultural variance. Some critics have pointed to methodological flaws in cross-cultural psychological research, and claim that serious shortcomings in the theoretical and methodological bases used impede, rather than help the scientific search for universal principles in psychology. Cross-cultural psychologists are turning more to the study of how differences (variance) occur, rather than searching for universals in the style of physics or chemistry. While cross-cultural psychology represented only a minor area of psychology prior to WWII, it began to grow in importance during the 1960s. In 1971, the interdisciplinary Society for Cross-Cultural Research (SCCR) was founded, and in 1972 the International Association for Cross-Cultural Psychology (IACCP) was established. Since then, this branch of psychology has continued to expand as there has been an increasing popularity of incorporating culture and diversity into studies of numerous psychological phenomena. Cross-cultural psychology is differentiated from cultural psychology, which refers to the branch of psychology that holds that human behavior is strongly influenced by cultural differences, meaning that psychological phenomena can only be compared with each other across cultures to a limited extent. In contrast, cross-cultural psychology includes a search for possible universals in behavior and mental processes. Cross-cultural psychology "can be thought of as a type [of] research methodology, rather than an entirely separate field within psychology". In addition, cross-cultural psychology can be distinguished from international psychology which centers around the global expansion of psychology especially during recent decades. Nevertheless, cross-cultural psychology, cultural psychology, and international psychology are united by a common concern for expanding psychology into a universal discipline capable of understanding psychological phenomena across cultures and in a global context.
  • 2.8K
  • 18 Oct 2022
Topic Review
Coyote Reconnaissance Vehicle
The Light Armoured Vehicle II (LAV II) Coyote (and the related Bison) are armoured cars (or armoured personnel carriers) built by General Dynamics Land Systems Canada for the Canadian Forces. They are a later generation of the LAV-25 and of the same family as the Australian ASLAV, as all are part of the Light Armoured Vehicle family produced by General Dynamics Land Systems - Canada and based on the MOWAG Piranha 8x8.
  • 2.8K
  • 03 Nov 2022
Topic Review
Amazon Elastic Compute Cloud
Amazon Elastic Compute Cloud (EC2) is a part of Amazon.com's cloud-computing platform, Amazon Web Services (AWS), that allows users to rent virtual computers on which to run their own computer applications. EC2 encourages scalable deployment of applications by providing a web service through which a user can boot an Amazon Machine Image (AMI) to configure a virtual machine, which Amazon calls an "instance", containing any software desired. A user can create, launch, and terminate server-instances as needed, paying by the second for active servers – hence the term "elastic". EC2 provides users with control over the geographical location of instances that allows for latency optimization and high levels of redundancy. In November 2010, Amazon switched its own retail website platform to EC2 and AWS.
  • 2.8K
  • 04 Nov 2022
Topic Review
List of Tall Ships
A list of tall ships afloat as of March 2012, listed alphabetically by vessel name:
  • 2.8K
  • 24 Nov 2022
Topic Review
Naringin
Polyphenols comprise a number of natural substances, such as flavonoids, that show interesting biological effects. Among these substances is naringin, a naturally occurring flavanone glycoside found in citrus fruits and Chinese medicinal herbs. Several studies have shown that naringin has numerous biological properties, including cardioprotective, cholesterol-lowering, anti-Alzheimer’s, nephroprotective, antiageing, antihyperglycemic, antiosteoporotic and gastroprotective, anti-inflammatory, antioxidant, antiapoptotic, anticancer and antiulcer effects. Despite its multiple benefits, the clinical application of naringin is severely restricted due to its susceptibility to oxidation, poor water solubility, and dissolution rate.
  • 2.8K
  • 24 Mar 2023
Topic Review
Distribution Channel Selection
The selection of the appropriate distribution channel is crucial for the success of any business dealing with physical goods. When dealing with this selection, it is crucial to have an effective decision support system (DSS) that can assist with such decisions. 
  • 2.8K
  • 15 Oct 2023
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