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HandWiki. UK Biobank. Encyclopedia. Available online: https://encyclopedia.pub/entry/28669 (accessed on 24 September 2026).
HandWiki. UK Biobank. Encyclopedia. Available at: https://encyclopedia.pub/entry/28669. Accessed September 24, 2026.
HandWiki. "UK Biobank" Encyclopedia, https://encyclopedia.pub/entry/28669 (accessed September 24, 2026).
HandWiki. (2022, October 10). UK Biobank. In Encyclopedia. https://encyclopedia.pub/entry/28669
HandWiki. "UK Biobank." Encyclopedia. Web. 10 October, 2022.
UK Biobank
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The content is sourced from: https://handwiki.org/wiki/Biology:UK_Biobank

UK Biobank is a large long-term biobank study in the United Kingdom (UK) which is investigating the respective contributions of genetic predisposition and environmental exposure (including nutrition, lifestyle, medications etc.) to the development of disease. It began in 2006. Based in Stockport, Greater Manchester, it is incorporated as a limited company and registered charity in England and Wales, and registered as a charity in Scotland.

environmental exposure biobank genetic predisposition

References

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  2. Reviewers' comments on Draft protocol, and responses http://www.mrc.ac.uk/index/strategy-strategy/strategy-science_strategy/strategy-strategy_implementation/strategy-government_spending_review_initiatives/strategy-biobank.htm
  3. Andy Coghlan: One million people, one medical gamble. New Scientist, 20 January 2006 https://www.newscientist.com/channel/health/mg18925353.800
  4. Regalado, Antonio (2017-11-15). "UK Biobank supercharges medicine with gene data on 500,000 Brits" (in en). MIT Technology Review. https://www.technologyreview.com/s/609184/uk-biobank-supercharges-medicine-with-gene-data-on-500000-brits/. 
  5. Zhang, Sarah (2017-11-06). "What Happens When You Put 500,000 People's DNA Online" (in en-US). The Atlantic. https://www.theatlantic.com/science/archive/2017/11/what-happens-when-you-put-500000-peoples-dna-online/543747/. 
  6. Littlejohns, Thomas J.; Sudlow, Cathie; Allen, Naomi E.; Collins, Rory (2017). "UK Biobank: opportunities for cardiovascular research". European Heart Journal 40 (14): 1158–1166. doi:10.1093/eurheartj/ehx254. PMID 28531320.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=6451771
  7. Sarah Hall: £61m medical experiment begins The Guardian , 22 August 2006 https://www.theguardian.com/science/story/0,,1855468,00.html
  8. UK Biobank Ethics and Governance Framework . UK Biobank, October 2007 http://www.ukbiobank.ac.uk/docs/EGF20082.pdf
  9. Ethics and Governance Framework for UK Biobank published for comment. Wellcome Trust, 22 September 2003 http://www.wellcome.ac.uk/News/Media-office/Press-releases/2003/wtd002848.htm
  10. Rules for UK Biobank revealed. BBC News, 24 September 2003 http://news.bbc.co.uk/1/hi/health/3134482.stm
  11. Ethics and Governance Council formed to oversee UK Biobank Wellcome Trust, 1 November 2004 http://www.wellcome.ac.uk/News/Media-office/Press-releases/2004/WTX022802.htm
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  14. "How 500,000 Britons are critical to assessing global disease risk". Financial Times. 22 August 2018. https://www.ft.com/content/80c82a0a-a48f-11e8-8ecf-a7ae1beff35b?emailId=5b7bce24992e45000493055c. 
  15. (30 March 2012) UK biobank opens to researchers BBC News, Health, Retrieved 30 March 2015 https://www.bbc.co.uk/news/health-17553931
  16. "Approved research summary" (in en-US). 2017-05-31. http://www.ukbiobank.ac.uk/approved-research/. 
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  18. (2015) UK Biobank; Large Scale Data Collection Axivity company web page, Retrieved 30 March 2015 http://axivity.com/case-studies/biobank
  19. "AX3 3-axis logging accelerometer". 8 December 2020. https://github.com/digitalinteraction/openmovement/wiki/AX3. 
  20. [1] Large Scale Population Assessment of Physical Activity Using Wrist Worn Accelerometers: The UK Biobank Study
  21. [2] UK Biobank Data Showcase - Physical activity measurement
  22. Welsh, Samantha; Peakman, Tim; Sheard, Simon; Almond, Rachael (2017-01-01). "Comparison of DNA quantification methodology used in the DNA extraction protocol for the UK Biobank cohort". BMC Genomics 18 (1): 26. doi:10.1186/s12864-016-3391-x. ISSN 1471-2164. PMID 28056765.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5217214
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  24. Elliott, L.T. (2018). "Genome-wide association studies of brain imaging phenotypes in UK Biobank". Nature 562 (7726): 210–216. doi:10.1038/s41586-018-0571-7. PMID 30305740. Bibcode: 2018Natur.562..210E.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=6786974
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  26. "UK Biobank reveals substantial variation in rates of previous COVID-19 infection across the UK". UK Biobank. 30 July 2020. https://www.ukbiobank.ac.uk/2020/07/uk-biobank-reveals-substantial-variation-in-rates-of-previous-covid-19-infection-across-the-uk/. 
  27. Miller, K.L. (2016). "Multimodal population brain imaging in the UK Biobank prospective epidemiological study". Nature Neuroscience 19 (11): 1523–1536. doi:10.1038/nn.4393. PMID 27643430.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5086094
  28. Alfaro-Almagro, F. (2016). "Image processing and Quality Control for the first 10,000 brain imaging datasets from UK Biobank". NeuroImage 19: 1523–1536. doi:10.1016/j.neuroimage.2017.10.034. PMID 29079522.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=5770339
  29. Alfaro Almagro, F. (25 April 2017). "Image Processing and Quality Control for the first 10,000 Brain Imaging Datasets from UK Biobank". bioRxiv 10.1101/130385. https://doi.org/10.1101%2F130385
  30. Why have you contacted me? http://www.ukbiobank.ac.uk/faqs/contacted.php
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  32. Agrawal, Raag; Prabakaran, Sudhakaran (2020-03-05). "Big data in digital healthcare: lessons learnt and recommendations for general practice". Heredity 124 (4): 525–534. doi:10.1038/s41437-020-0303-2. ISSN 0018-067X. PMID 32139886.  http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=7080757
  33. Daily Telegraph 2004 https://www.telegraph.co.uk/science/science-news/3326762/62m-Biobank-may-not-be-worth-it-says-professor.html
  34. Bingham, S.; Riboli, E. (2004). "Diet and cancer — the European Prospective Investigation into Cancer and Nutrition". Nature Reviews Cancer 4 (3): 206–15. doi:10.1038/nrc1298. PMID 14993902. http://www.angelfire.com/scary/lancelot/pdf/diet_and_cancer.pdf. 
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  38. An early description of the vision and business model is in Stephen D. Moore, "Biotech firm turns Iceland into a giant genetics lab," Wall Street Journal (subscription required), 3 July 1997. Another early account of the entreprise is by Michael Specter, "Decoding Iceland," The New Yorker (subscription required), 18 January 1999 https://www.wsj.com/articles/SB867882460839119500
  39. Anna Azvolinsky, "Master Decoder: A Profile of Kári Stefánsson," The Scientist, 1 March 2019 https://www.the-scientist.com/profile/master-decoder--a-profile-of-kri-stefnsson-65517
  40. All of the companies principal scientific discoveries are listed in chronological order on the publications page of its website https://www.decode.com/publications/
  41. On acquisition in 2012, its rationale in broad context, as well as deCODE being left in independent control over its data, see Matt Herper, " With DeCode deal, Amgen aims to discover drugs like we meant to in 1999," Forbes, 10 December 2012 https://www.forbes.com/sites/matthewherper/2012/12/10/with-decode-deal-amgen-aims-to-discover-drugs-like-we-meant-to-1999/#32a37c9c130f
  42. Amgen's former Chief Scientific officer, Sean Harper, in Asher Mullard, "An audience with...Sean Harper," Nature Reviews Drug Discovery (subscription required), Vol 17, pp 10-11, January 2018 https://www.nature.com/articles/nrd.2017.262
  43. Gallagher, James (26 March 2015) DNA of 'an entire nation' assessed BBC News, Health, Retrieved 29 March 2015 https://www.bbc.co.uk/news/health-32024158
  44. Statistics on portal activity in: Nordic Alliance for Clinical Genomics, "NACG 6th Clinical workshop report," 21 November 2018, p.9 https://nordicclinicalgenomics.org/assets/resources/201811-nacg-6th-ws-report-final.pdf
  45. Frank, Lane (6 October 2000). "Give and Take—Estonia's New Model for a National Gene Bank". genomenewsnetwork.org. http://www.genomenewsnetwork.org/articles/10_00/Estonias_genebank.shtml. 
  46. Frank, L. (1999). "GENETIC DISEASE:Storm Brews over Gene Bank of Estonian Population". Science 286 (5443): 1262–1263. doi:10.1126/science.286.5443.1262. PMID 10610525.  https://dx.doi.org/10.1126%2Fscience.286.5443.1262
  47. "Kui pikalt sa elad?" (in et). https://geenidoonor.ee/. 
  48. (2014) China Kadoorie Biobank University of Oxford, Retrieved 28 January 2015 http://www.ckbiobank.org/site/
  49. "National Institutes of Health (NIH) — All of Us web page" (in en). 2018. https://allofus.nih.gov/. 
  50. Cunningham, Paige Winfield (2018-01-16). "The Health 202: NIH wants 1 million Americans to contribute to new pool of gene data" (in en-US). Washington Post. ISSN 0190-8286. https://www.washingtonpost.com/news/powerpost/paloma/the-health-202/2018/01/16/the-health-202-nih-wants-1-million-americans-to-contribute-to-new-pool-of-gene-data/5a5ba45a30fb0469e8840135/. 
  51. https://www.researchallofus.org/
  52. Scholtens, Salome; Smidt, Nynke; Swertz, Morris A.; Bakker, Stephan JL; Dotinga, Aafje; Vonk, Judith M.; van Dijk, Freerk; Zon, Van et al. (2015-08-01). "Cohort Profile: LifeLines, a three-generation cohort study and biobank" (in en). International Journal of Epidemiology 44 (4): 1172–1180. doi:10.1093/ije/dyu229. ISSN 0300-5771. PMID 25502107.  https://dx.doi.org/10.1093%2Fije%2Fdyu229
  53. "cohort study and biobank" (in nl-NL). https://www.lifelines.nl/researcher/biobank-lifelines. 
  54. "FinnGen, a global research project focusing on genome data of 500,000 Finns, launched" (in en). American Association for the Advancement of Science. 2017-12-19. https://www.eurekalert.org/pub_releases/2017-12/uoh-fag121917.php. 
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