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Topic Review
Canis Major
Canis Major, Latin for "Greater Dog," is one of the most prominent constellations in the southern celestial hemisphere. Often depicted as one of Orion's hunting dogs in Greek mythology, Canis Major is best known for its brightest star, Sirius, also called the Dog Star, which is the brightest star in the night sky. With its distinctive shape and rich cultural significance, Canis Major has fascinated astronomers and storytellers throughout history.
  • 3.7K
  • 29 Feb 2024
Topic Review
Hyaluronic Acid in Cosmeceuticals
Hyaluronic acid (HA) is a polysaccharide belonging to the glycosaminoglycans, made up of disaccharide units constituted of N-acetylglucosamine and D-glucuronic acid.
  • 3.7K
  • 29 Jul 2021
Topic Review
Potential Effects of Time Pressure on Intelligence Tests
Intelligence tests are often performed under time constraints for practical reasons, but the effects of time pressure on reasoning performance are poorly understood. A brief review of major expected effects of time pressure is presented herein, which includes forcing participants to skip items, convoking a mental speed factor, constraining response times, qualitatively altering cognitive processing, affecting anxiety and motivation, and interacting with individual differences. 
  • 3.7K
  • 14 Jul 2023
Topic Review
Participatory Methods for Urban Development
Despite the fact that vulnerable communities are the most affected by unplanned cities, considerably less attention has been given to involving them in urban development in order to ensure equitable outcomes. In this regard, there is an urgent need for governments to introduce and enforce processes that allow citizens, including vulnerable communities, to participate in development planning and policymaking. However, at present, there is a lack of guidance for practitioners regarding the definition of a clear purpose of community engagement and the selection of appropriate participatory methods to fulfil the set purpose. This study provides a thorough account of the participatory methods that can be used to achieve various engagement goals throughout the urban development process. This structured literature review used 71 reports published from 2000 to 2020. The review revealed 34 participatory methods, wherein most of the methods are devoted to informing, consulting and involving communities, whilst only a few methods are available for interactive public participation that supports true collaboration and empowerment. The study identified 12 purposes of community engagement in urban development, and mapped the 34 participatory methods for achieving them. The analysed case studies showed that the current community engagement practices are mainly in the pre-design and briefing stages of the urban development processes, and that most projects are aiming to achieve the ‘inform’ and ‘consult’ levels of engagement, with a few aiming to achieve the ‘involve’ and ‘collaborate’ levels. This study shows that community engagement is often overlooked during the professional design, development and post-development phases. The paper presents an onion model which can be used by practitioners to choose appropriate participatory methods based on the intended urban development phase, the engagement level and the purpose of the community engagement.
  • 3.7K
  • 16 Aug 2021
Topic Review
Safeguarding Intangible Cultural Heritage: The Amazonian Kichwa People
Indigenous peoples are the holders of a great diversity of tangible and intangible cultural heritage (uses, representations, expressions, knowledge and techniques), also known as living heritage. 
  • 3.7K
  • 11 Jan 2022
Topic Review
Wannacry
The WannaCry ransomware attack was a worldwide cyberattack in May 2017 by the WannaCry ransomware cryptoworm, which targeted computers running the Microsoft Windows operating system by encrypting data and demanding ransom payments in the Bitcoin cryptocurrency. It propagated through EternalBlue, an exploit developed by the United States National Security Agency (NSA) for older Windows systems. EternalBlue was stolen and leaked by a group called The Shadow Brokers a month prior to the attack. While Microsoft had released patches previously to close the exploit, much of WannaCry's spread was from organizations that had not applied these, or were using older Windows systems that were past their end-of-life. These patches were imperative to organizations' cyber security but many were not implemented due to ignorance of their importance. Some have claimed a need for 24/7 operation, aversion to risking having formerly working applications breaking because of patch changes, lack of personnel or time to install them, or other reasons. The attack began at 07:44 UTC on 12 May 2017 and was halted a few hours later at 15:03 UTC by the registration of a kill switch discovered by Marcus Hutchins. The kill switch prevented already infected computers from being encrypted or further spreading WannaCry. The attack was estimated to have affected more than 200,000 computers across 150 countries, with total damages ranging from hundreds of millions to billions of United States dollar . Security experts believed from preliminary evaluation of the worm that the attack originated from North Korea or agencies working for the country. In December 2017, the United States and United Kingdom formally asserted that North Korea was behind the attack. A new variant of WannaCry forced Taiwan Semiconductor Manufacturing Company (TSMC) to temporarily shut down several of its chip-fabrication factories in August 2018. The virus spread to 10,000 machines in TSMC's most advanced facilities.
  • 3.7K
  • 23 Oct 2022
Topic Review
Indian Gray Mongoose
The Indian Gray Mongoose (Herpestes edwardsii) is a small carnivorous mammal native to the Indian subcontinent. Known for its sleek gray fur and long, slender body, the Indian Gray Mongoose is highly adaptable and can be found in a variety of habitats, including forests, grasslands, and urban areas. As a skilled predator, it preys on a diverse range of small animals, including rodents, snakes, birds, and insects, playing a crucial role in controlling pest populations and maintaining ecosystem balance.
  • 3.7K
  • 15 Mar 2024
Topic Review
Bifidobacteria
Bifidobacteria are high G+C Gram positive bacteria belonging to the Actinobacteria phylum isolated from the gastrointestinal tract of different mammals, birds and social insects.
  • 3.7K
  • 11 Jan 2021
Topic Review
Silicate Minerals
Silicate minerals are rock-forming minerals made up of silicate groups. They are the largest and most important class of minerals and make up approximately 90 percent of the Earth's crust. In mineralogy, silica (silicon dioxide) SiO2 is usually considered a silicate mineral. Silica is found in nature as the mineral quartz, and its polymorphs. On Earth, a wide variety of silicate minerals occur in an even wider range of combinations as a result of the processes that have been forming and re-working the crust for billions of years. These processes include partial melting, crystallization, fractionation, metamorphism, weathering, and diagenesis. Living organisms also contribute to this geologic cycle. For example, a type of plankton known as diatoms construct their exoskeletons ("frustules") from silica extracted from seawater. The frustules of dead diatoms are a major constituent of deep ocean sediment, and of diatomaceous earth.
  • 3.7K
  • 25 Oct 2022
Topic Review
Gastrointestinal Disorders and Metabolic Syndrome
Abstract Gastrointestinal (GI) diseases, which include gastrointestinal reflux disease, gastric ulceration, inflammatory bowel disease, and other functional GI disorders, have become prevalent in a large part of the world population. Metabolic syndrome (MS) is cluster of disorders including obesity, hyperglycemia, hyperlipidemia, and hypertension, and is associated with high rate of morbidity and mortality. Gut dysbiosis is one of the contributing factors to the pathogenesis of both GI disorder and MS, and restoration of normal flora can provide a potential protective approach in both these conditions. Bioactive dietary components are known to play a significant role in the maintenance of health and wellness, as they have the potential to modify risk factors for a large number of serious disorders. Different classes of functional dietary components, such as dietary fibers, probiotics, prebiotics, polyunsaturated fatty acids, polyphenols, and spices, possess positive impacts on human health and can be useful as alternative treatments for GI disorders and metabolic dysregulation, as they can modify the risk factors associated with these pathologies. Their regular intake in sufficient amounts also aids in the restoration of normal intestinal flora, resulting in positive regulation of insulin signaling, metabolic pathways and immune responses, and reduction of low-grade chronic inflammation. This review is designed to focus on the health benefits of bioactive dietary components, with the aim of preventing the development or halting the progression of GI disorders and MS through an improvement of the most important risk factors including gut dysbiosis.
  • 3.7K
  • 22 Jul 2020
Topic Review Video Peer Reviewed
Sheet Barrier and Intubating Stylet
Coronavirus disease 2019 (COVID-19), a respiratory syndrome caused by SARS-CoV-2, can be transmitted through respiratory droplets and aerosols of droplet nuclei. Aerosol-generating medical procedures (AGMP) are needed to take care of critically ill patients but place health care providers at risk of infection. With limited supplies of personal protective equipment (PPE), barrier systems were developed to help protect health care providers during tracheal intubation. The video intubating stylet shows promise to become the preferred intubation device in conjunction with plastic sheet barriers during the COVID-19 pandemic.
  • 3.7K
  • 13 Apr 2022
Topic Review
Integrative Body Psychotherapy
Integrative body psychotherapy (IBP) is a psychotherapy that recognizes and treats the somatic (physical), psychological/emotional, and spiritual nature of a human being. It is based on the premise that the body, mind, and spirit are not separate, but rather integrated parts of a whole person. Every experience has a physical, mental, emotional, and spiritual aspect, which manifests internally within the body and externally in relationship to others. IBP was first developed by Jack Lee Rosenberg starting in the late 1970s (see § History, below).
  • 3.7K
  • 14 Oct 2022
Topic Review
Waterway Cargo Transportation
Water transportation is an important part of comprehensive transportation and plays a critical role in a country’s economic development. The world’s cargo transportation is dominated by waterway transportation, and maritime transportation Systems (MTS) are the main part of the waterway transportation system. The flow of goods plays a key role in the economic development of the ports along the route. The sustainable development of maritime transportation, the maritime transportation economy and the environment have great practical significance.
  • 3.7K
  • 21 Nov 2022
Topic Review
The Dog–Owner Relationship
The Cat/Dog–Owner Relationship Scale (C/DORS) is a questionnaire aimed to assess specific aspects of the pet–owner relationship. While the entire scale can be administered to both dog and cat owners, its validity and reliability have never been tested on dogs. Furthermore, validity and reliability of a scale may change depending on the respondents’ language and cultural background. Since the C/DORS was developed in English, we aimed to translate it into Italian and assess its validity and reliability on a sample of Italian dog owners. The response scale was modified to improve the variability of the owners’ responses. Overall, validity and reliability were good. The scale had the same three-factor structure (Perceived Emotional Closeness = PEC, Pet–Owner Interactions = POI, Perceived Costs = PC) reported for the original English version, although some items were removed because they did not fit the statistical model. The PEC subscale had the highest correlations with the subscales of the Lexington Attachment to Pets Scale. Finally, being a student owner was associated with higher PEC and POI scores. Conversely, owning a dog with behavioural problems was associated with lower PEC and higher PC. Owners whose dogs lived outdoors reported lower POI. Pet dog owners reported higher PEC than AAI dog owners.
  • 3.7K
  • 17 Aug 2021
Topic Review
Deriving Vectorcardiography from 12-Lead ECG
Vectorcardiography (VCG) is a valuable diagnostic tool that complements the standard 12-lead ECG by offering additional spatiotemporal information to clinicians. However, due to the need for additional measurement hardware and too many electrodes in a clinical scenario if performed along with a standard 12-lead, there is a need to find methods to derive the VCG from the ECG.
  • 3.7K
  • 22 May 2023
Topic Review
Singlet Fission
Singlet fission is a process that occurs in organic molecules upon the absorption of light. It produces a singlet excited state (S1) in one molecule that is shared with a neighbouring one in the ground state (S0), thus splitting into two triplet excited states (T1).
  • 3.7K
  • 01 Jun 2021
Topic Review
Role of Glutathione in Cancer
       Molecular changes in the glutathione antioxidant system and disturbances in its homeostasis have been implicated in tumor initiation, progression, and treatment response with glutathione having both protective and pathogenic roles. Although in healthy cells it is crucial for the removal and detoxification of carcinogens, elevated glutathione levels in tumor cells are associated with tumor progression and increased resistance to chemotherapeutic drugs. Recently, several novel therapies have been developed to target the glutathione antioxidant system in tumors as a means for increased response and decreased drug resistance. In this comprehensive review we explore glutathione functionalities and different therapeutic approaches and their development through experimental and computational approaches. 
  • 3.7K
  • 03 Nov 2020
Topic Review
Myrica esculenta
Myrica esculenta (Myricaceae) is a popular medicinal plant most commonly found in the sub-tropical Himalayas. It is widely used in folk medicine to treat several ailments such as asthma, cough, chronic bronchitis, ulcers, inflammation, anemia, fever, diarrhea, and ear, nose, and throat disorders. Due to its multidimensional pharmacological and therapeutic effects, it is well recognized in the ayurvedic pharmacopeia.
  • 3.7K
  • 11 Mar 2025
Topic Review
Panama as a Tax Haven
The Republic of Panama is one of the oldest and best-known tax havens in the Caribbean, as well as one of the most established in the region. Panama has had a reputation for tax avoidance since the early 20th century, and Panama has been cited repeatedly in recent years as a jurisdiction which does not cooperate with international tax transparency initiatives. Panama's offshore sector is intimately tied to the Panama canal, which has made it a gateway and entrepôt for international trade. There are strong similarities between Panama and other leading tax havens like Hong Kong, Singapore and Dubai. On paper at least, Panama has the largest shipping fleet in the world, greater than those of the US and China combined, according to the Tax Justice Network.
  • 3.7K
  • 16 Nov 2022
Topic Review
3p Deletion Syndrome
3p deletion syndrome is a condition that results from a chromosomal change in which a small piece of chromosome 3 is deleted in each cell. The deletion occurs at the end of the short (p) arm of the chromosome. This chromosomal change often leads to intellectual disability, developmental delay, and abnormal physical features.
  • 3.7K
  • 23 Dec 2020
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