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Topic Review
Smart Window
Dimming and scattering control are two of the major features of smart windows, which provide adjustable sunlight intensity and protect the privacy of people in a building. A hybrid photo- and electrical-controllable smart window that exploits salt and photochromic dichroic dye-doped cholesteric liquid crystal was developed. The photochromic dichroic dye causes a change in transmittance from high to low upon exposure to sunlight. When the light source is removed, the smart window returns from colored to colorless. The salt-doped cholesteric liquid crystal can be bi-stably switched from transparent into the scattering state by a low-frequency voltage pulse and switched back to its transparent state by a high-frequency voltage pulse. In its operating mode, an LC smart window can be passively dimmed by sunlight and the haze can be actively controlled by applying an electrical field to it; it therefore exhibits four optical states—transparent, scattering, dark clear, and dark opaque. Each state is stable in the absence of an applied voltage. This smart window can automatically dim when the sunlight gets stronger, and according to user needs, actively adjust the haze to achieve privacy protection.
  • 1.3K
  • 22 Oct 2020
Topic Review
Nanomaterials‘ effects on Plants under Salt Stress
Plant salinity resistance results from a combination of responses at the physiological, molecular, cellular, and metabolic levels. Nanoparticles are used as an emerging tool to stimulate specific biochemical reactions related to plant ecophysiological output because of their small size, increased surface area and absorption rate, efficient catalysis of reactions, and adequate reactive sites. Regulated ecophysiological control in saline environments could play a crucial role in plant growth promotion and survival of plants under suboptimal conditions. Plant biologists are seeking to develop a broad profile of genes and proteins that contribute to plant salt resistance. These plant metabolic profiles can be developed due to advancements in genomic, proteomic, metabolomic, and transcriptomic techniques.
  • 1.3K
  • 11 Mar 2022
Topic Review
Chitosan in Metal Nanoparticles Synthesis
Chitosan (CS) has been widely used as a surface coating for metal nanoparticles. CS can work as a reducing agent, a shape director, or a size-controllable agent in the synthesis of metal nanoparticles. The previous studies have shown that functionalizing the surface of metal nanoparticles by CS can offer many advantages, including improving physicochemical stability, a drug carrier, controlling drug release, promoting muco-adhesiveness and tissue penetration, encouraging cell interactions, and enhancing antimicrobial effects.
  • 1.3K
  • 19 Feb 2021
Topic Review
RNA-Based Nano-Theranostic Approaches for Cancer Management
In the fight against cancer, early diagnosis is critical for effective treatment. Traditional cancer diagnostic technologies, on the other hand, have limitations that make early detection difficult. Therefore, multi-functionalized nanoparticles (NPs) and nano-biosensors have revolutionized the era of cancer diagnosis and treatment for targeted action via attaching specified and biocompatible ligands to target the tissues, which are highly over-expressed in certain types of cancers. Advancements in multi-functionalized NPs can be achieved via modifying molecular genetics to develop personalized and targeted treatments based on RNA interference. Modification in RNA therapies utilized small RNA subunits in the form of small interfering RNAs (siRNA) for overexpressing the specific genes of, most commonly, breast, colon, gastric, cervical, and hepatocellular cancer.
  • 1.3K
  • 15 Dec 2021
Topic Review
Hybrid Nanobioengineered Nanomaterial-Based Electrochemical Biosensors
Nanobioengineered-based hybrid electrochemical biosensors exploit the synergistic properties of hybrid systems that connect biomolecules with nanomaterials to engineer highly sensitive biosensing platforms for the specific electrochemical detection of different target analytes.
  • 1.3K
  • 30 Jun 2022
Topic Review
Spinel Ferrite (MFe2O4) Chemiresistive Based Gas Sensors
Gas-sensing technology has gained significant attention in recent years due to the increasing concern for environmental safety and human health caused by reactive gases. In particular, spinel ferrite (MFe2O4), a metal oxide semiconductor with a spinel structure, has emerged as a promising material for gas-sensing applications. 
  • 1.3K
  • 02 Aug 2023
Topic Review
CDs as Antimicrobial Agents
Carbon dots (CDs) have been identified as a promising class of photosensitiser nanomaterials for the specific detection and inactivation of different bacterial species. CDs possess exceptional and tuneable chemical and photoelectric properties that make them excellent candidates for antibacterial theranostic applications, such as great chemical stability, high water solubility, low toxicity and excellent biocompatibility. 
  • 1.3K
  • 29 Jul 2021
Topic Review
Molecular Mechanisms of Exosomes
Exosomes are effective therapeutic vehicles that may transport their substances across cells. They are shown to possess the capacity to affect cell proliferation, migration, anti-apoptosis, anti-scarring, and angiogenesis, via the action of transporting molecular components. Possessing immense potential in regenerative medicine, exosomes, especially stem cell-derived exosomes, have the advantages of low immunogenicity, minimal invasiveness, and broad clinical applicability. Exosome biodistribution and pharmacokinetics may be altered, in response to recent advancements in technology, for the purpose of treating particular illnesses.
  • 1.3K
  • 12 Apr 2023
Topic Review
Nanotechnologies for Drug Delivery to the Brain
Drug delivery to the brain has been one of the toughest challenges researchers have faced to develop effective treatments for brain diseases. Owing to the blood–brain barrier (BBB), only a small portion of administered drug can reach the brain. A consequence of that is the need to administer a higher dose of the drug, which, expectedly, leads to a variety of unwanted side effects. Research in a variety of different fields has been underway for the past couple of decades to address this very serious and frequently lethal problem. One area of research that has produced optimistic results in recent years is nanomedicine. Nanomedicine is the science birthed by fusing the fields of nanotechnology, chemistry and medicine into one. Many different types of nanomedicine-based drug-delivery systems are currently being studied for the sole purpose of improved drug delivery to the brain.
  • 1.2K
  • 26 Jan 2022
Topic Review
Microfluidic High-Throughput Platforms
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude.
  • 1.2K
  • 11 Feb 2021
Topic Review
Nanocomposite materials for Wound Healing
Materials science is a field in which nanotechnology is being greatly explored, due to how much the bulk and surface properties previously mentioned, such as structural tunability, functionalization, and physicochemical stability, etc., are observed to change with diverse synthetization protocols in order to form customized nanostructured materials. Materials properties, such as shape, size, crystal structure, and surface roughness, can be taken advantage of and are currently being applied to practically any area of the biomedical field, such as wound healing and drug delivery around the globe with exceedingly successful results. The use of nanostructured materials in the form of nanoparticles, nanofibers, and any shape given at the nanoscale (1–100 nm), applied towards biotechnological and/or biomedical applications, such as wound healing, treatment of emerging pollutants, and drug delivery, has been exponentially growing over the past few decades.
  • 1.2K
  • 27 May 2021
Topic Review
Green Synthesis and Biomedical Application of Selenium Nanoparticles
Selenium nanoparticles (SeNPs) are extremely popular objects in nanotechnology. “Green” synthesis has special advantages due to the growing necessity for environmentally friendly, non-toxic, and low-cost methods. 
  • 1.2K
  • 22 Dec 2023
Topic Review
Synthesis and Characterization of Proteinoid and Nanocapsules
Proteinoids are random polymers composed of amino acids synthesized by stepwise thermal polymerization. They were discovered and studied in the 1950s by Fox and coworkers, who suggested that they formed spontaneously by high heat at the beginning of life on Earth. Nanocapsules (NCs) form spontaneously by heating proteinoids to about 70 °C in an aqueous solution to completely dissolve the polymers, followed by slow cooling to room temperature.
  • 1.2K
  • 27 Apr 2023
Topic Review
Biogenic Silver Nanoparticles for Their Biomedical Applications
Nanoparticles can be synthesized through physical, chemical, and biological routes, where biologically synthesized nanoparticles are also referred to as biogenic-synthesized nanoparticles or bionanoparticles. Bionanoparticles exploit the inherent reducing property of biological entities to develop cost-effective, non-toxic, time-efficient, sustainable, and stable nanosized particles. There is a wide array biomedical focus on metallic nanoparticles, especially silver nanoparticles, due to their distinctive physiochemical properties making them a suitable therapeutic molecule carrier. This research aims to provide a broad insight into the various classes of living organisms that can be exploited for the development of silver nanoparticles, and elaboratively review the interdisciplinary biomedical applications of biogenically synthesized silver nanoparticles in health and life sciences domains.
  • 1.2K
  • 13 Mar 2023
Topic Review
Nanocellulose’s Unique Characteristics as a Chemical Sensor
Composites can be derived from plant-based nanomaterials, among which is nanocellulose which has attracted significant attention as potential replacements for their more conventional petroleum-derived counterparts for use in chemical sensing applications.
  • 1.2K
  • 26 Oct 2022
Topic Review
Electrospun Nanofibers for Chemical Separation
The separation and purification of specific chemicals from a mixture have become necessities for many environments, including agriculture, food science, and pharmaceutical and biomedical industries. Electrospun nanofiber membranes are promising materials for the separation of various species such as particles, biomolecules, dyes, and metals from liquids because of the combined properties of a large specific surface, light weight, high porosity, good connectivity, and tunable wettability. This paper reviews the recent progress in the design and fabrication of electrospun nanofibers for chemical separation. Different capture mechanisms including electrostatic, affinity, covalent bonding, chelation, and magnetic adsorption are explained and their distinct characteristics are highlighted. Finally, the challenges and future aspects of nanofibers for membrane applications are discussed.
  • 1.2K
  • 28 Oct 2020
Topic Review
Protein-based Subunit Nanovaccine
Protein-based subunit nanovaccines are typically composed of native or altered protein antigens that can self-assemble into nanoparticles, or antigens associated with nanoparticles through covalent or noncovalent interactions. Characteristically, nanovaccines are 1 to 1000 nm in size which generally facilitates the induction of stronger immune responses.
  • 1.2K
  • 18 Oct 2021
Topic Review
Carbon Nanoparticles
Currently, carbon nanoparticles play a large role as carriers of various types of drugs, and also have applications in other fields of medicine, e.g., in tissue engineering, where they are used to reconstruct bone tissue. They also contribute to the early detection of cancer cells, and can act as markers in imaging diagnostics. Their antibacterial and anti-inflammatory properties are also known. This feature is particularly important in dental implantology, where various types of bacterial infections and implant rejection often occur. The search for newer and more effective treatments may lead to future use of nanoparticles on a large scale.
  • 1.2K
  • 22 Sep 2021
Topic Review
Natural Compounds: Advantages of Combination Therapy in Cancer
Cancer is one of the leading causes of death, and latest predictions indicate that cancer-related deaths will increase over the next few decades. Despite significant advances in conventional therapies, treatments are still far from ideal due to limitations such as lack of selectivity, non-specific distribution, and multidrug resistance. Some researches are focusing on the development of several strategies to improve the efficiency of chemotherapeutic agents and, as a result, overcome the challenges associated with conventional therapies. In this regard, combined therapy with natural compounds and other therapeutic agents, such as chemotherapeutics or nucleic acids, has recently emerged as a new strategy for tackling the drawbacks of conventional therapies.
  • 1.2K
  • 22 May 2023
Topic Review
Nanotechnology for Neurological Disorders after Long COVID Syndrome
Long-term neurological complications, persisting in patients who cannot fully recover several months after severe SARS-CoV-2 coronavirus infection, are referred to as neurological sequelae of the long COVID syndrome. Among the numerous clinical post-acute COVID-19 symptoms, neurological and psychiatric manifestations comprise prolonged fatigue, “brain fog”, memory deficits, headache, ageusia, anosmia, myalgias, cognitive impairments, anxiety, and depression lasting several months. Considering that neurons are highly vulnerable to inflammatory and oxidative stress damages following the overproduction of reactive oxygen species (ROS), neuroinflammation and oxidative stress have been suggested to dominate the pathophysiological mechanisms of the long COVID syndrome. It is emphasized that mitochondrial dysfunction and oxidative stress damages are crucial for the pathogenesis of neurodegenerative disorders. Importantly, antioxidant therapies have the potential to slow down and prevent disease progression. However, many antioxidant compounds display low bioavailability, instability, and transport to targeted tissues, limiting their clinical applications. Various nanocarrier types, e.g., liposomes, cubosomes, solid lipid nanoparticles, micelles, dendrimers, carbon-based nanostructures, nanoceria, and other inorganic nanoparticles, can be employed to enhance antioxidant bioavailability. Here, the potential of phytochemical antioxidants and other neuroprotective agents (curcumin, quercetin, vitamins C, E and D, melatonin, rosmarinic acid, N-acetylcysteine, and Ginkgo Biloba derivatives) in therapeutic strategies for neuroregeneration is highlighted. A particular focus is given to the beneficial role of nanoparticle-mediated drug-delivery systems in addressing the challenges of antioxidants for managing and preventing neurological disorders as factors of long COVID sequelae.  
  • 1.2K
  • 14 Mar 2023
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