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Topic Review
Sustainability Potentials of Integrated Multi-Trophic Aquaculture
Integrated multi-trophic aquaculture (IMTA) systems integrate the cultivation of species from different trophic levels. Uneaten feed, solid wastes, and dissolved nutrients are turned into harvestable and healthy food, making IMTA a driver for ecologically sustainable aquaculture. Its wider sustainability potentials arise from social, environmental, and economic sustainability enhancement options. 
  • 1.1K
  • 30 Nov 2022
Topic Review
Stylite
A stylite (from Greek στυλίτης, stylitēs, "pillar dweller", derived from στῦλος, stylos, "pillar", Classical Syriac: ܐܣܛܘܢܐ‎ ʼasṯonáyé) or pillar-saint is a type of Christian ascetic who lives on pillars, preaching, fasting and praying. Stylites believe that the mortification of their bodies would help ensure the salvation of their souls. Stylites were common in the early days of the Byzantine Empire. The first known stylite was Simeon Stylites the Elder who climbed a pillar in Syria in 423 and remained there until his death 37 years later.
  • 1.1K
  • 29 Nov 2022
Topic Review
Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) represent a group of neurodevelopmental disorders associated to social and behavioral impairments. Although dysfunctions in several signaling pathways have been associated to ASD, very few molecules have been identified as potentially effective drug targets in the clinics. Classically, research in the ASD field has focused on the characterization of pathways involved in neural development and synaptic plasticity, which support the pathogenesis of this group of diseases. More recently, immune system dysfunctions have been observed in ASD. In addition, high levels of reactive oxygen species (ROS), which cause oxidative stress, are present in ASD patients. In this review we will describe the major alterations in the expression of genes coding for enzymes involved in the ROS scavenging system, in both ASD patients and ASD mouse models. In addition, we will discuss, in the context of the most recent literature, the possibility that oxidative stress, inflammation and immune system disfunction may be connected to, and altogether support, the pathogenesis and/or severity of ASD. Finally, we will discuss about the possibility of novel treatments, aiming at counteracting the interplay ROS/inflammation in people with ASD.
  • 1.1K
  • 29 Oct 2020
Topic Review
Iris sibirica and Zantedeschia aetiopica
Z. aethiopica and I. sibirica are two flowering species that have been used as emergent vegetation for the treatment of domestic wastewater. Z. aethiopica is  in high demand in the national market in Mexico. The two species have a proven specific capacity to tolerate and take up pharmaceuticals  and heavy metals.
  • 1.1K
  • 09 Nov 2020
Topic Review
Taxol®
Taxol®, which is also known as paclitaxel, is a chemotherapeutic agent widely used to treat different cancers. Since the discovery of its antitumoral activity, Taxol® has been used to treat over one million patients, making it one of the most widely employed antitumoral drugs.
  • 1.1K
  • 13 Jan 2021
Topic Review
Mg2+ Transporters in Digestive Cancers
Magnesium (Mg2+) is one of the most important ions in health and is the second most abundant cation in the cell with a concentration estimated between 10 and 30 mM. Due to its importance, Mg2+, requires a specific transport system. In Mammals, several transporters have been identified (TRPM6/7, CNNM1/2/3/4, MAGT1, SLC41A1, MRS2). There is numerous evidence suggesting an association between Mg2+ intake and digestive cancer risk and/or development.
  • 1.1K
  • 02 Feb 2021
Topic Review
Phytotoxic Ozone Concentration
Tropospheric concentrations of phytotoxic ozone (O3) have undergone a great increase from preindustrial 10–15 ppbv to a present-day concentration of 35–40 ppbv in large parts of the industrialised world due to increased emissions of O3 precursors including NOx, CO, CH4 and volatile organic compounds.
  • 1.1K
  • 18 Mar 2021
Topic Review
Nutritional Management in Sheep
Nutritional management is one of the most important factors to ensure adequate productivity and to prevent wasting in sheep flocks.
  • 1.1K
  • 06 Apr 2021
Topic Review
Autophagy Modulators in Cancer Therapy
Autophagy is a process of self-degradation that plays an important role in removing damaged proteins, organelles or cellular fragments from the cell. 
  • 1.1K
  • 15 Jun 2021
Topic Review
Social Innovation Design
Social innovation design uses social resources and knowledge to meet the needs of society and put forward innovative schemes.
  • 1.1K
  • 22 Sep 2021
Topic Review
Reproductive Potential in Primula veris L. (Primulaceae)
Primula veris (Primulaceae) is a valuable medicinal plant. P. veris is a Euro-Siberian Temperate element distributed throughout most of temperate Europe and Western Asia. As with most species of the genus Primula, it is entomophilous with a great affinity between its flowers. Insect pollinators belong to Hymenoptera (mainly bumblebees and bees), Lepidoptera and Diptera.
  • 1.1K
  • 10 Nov 2021
Topic Review
Monitoring of Ecological Response to River Restoration
Nature-based solutions are widely advocated for freshwater ecosystem conservation and restoration. As increasing amounts of river restoration are undertaken, the need to understand the ecological response to different measures and where measures are best applied becomes more pressing. 
  • 1.1K
  • 14 Dec 2021
Topic Review
(−)-Methyl-Oleocanthal, a New Oleocanthal Metabolite
The antioxidant and anti-inflammatory responses of (−)-methyl-oleocanthal (met-OLE), a new metabolite of the extra virgin olive oil (EVOO) phenolic oleocanthal (OLE), were explored in lipopolysaccharide (LPS)-induced murine peritoneal macrophages. Possible signaling pathways and epigenetic modulation of histones were studied. Met-OLE inhibited LPS-induced intracellular reactive oxygen species (ROS) and nitrite (NO) production and decreased the overexpression of the pro-inflammatory enzymes COX-2, mPGES-1 and iNOS in murine macrophages.
  • 1.1K
  • 13 Jan 2022
Topic Review
Antifungal Preservation of Food by Lactic Acid Bacteria
Fungal growth and consequent mycotoxin release in food and feed threatens human health, which might even, in acute cases, lead to death. Control and prevention of foodborne poisoning is a major task of public health that will be faced in the 21st century. Nowadays, consumers increasingly demand healthier and more natural food with minimal use of chemical preservatives, whose negative effects on human health are well known. Biopreservation is among the safest and most reliable methods for inhibiting fungi in food. Lactic acid bacteria (LAB) are of great interest as biological additives in food owing to their Generally Recognized as Safe (GRAS) classification and probiotic properties. LAB produce bioactive compounds such as reuterin, cyclic peptides, fatty acids, etc., with antifungal properties.
  • 1.1K
  • 17 Feb 2022
Topic Review
Pt Nanocatalyst in Low Temperature Fuel Cells
Fuel cells (FCs) provide electricity via the generation of ion carriers by electrocatalysis at the electrodes as well as a positive or negative ion transport mechanism and direction of motion through electrolyte membranes. Pt nanomaterials are used in the catalytic layer components of low-temperature FCs associated with the clean H2 fuel industry, which are the most successful and typical examples of generating clean electric energy and power.
  • 1.1K
  • 29 Mar 2022
Topic Review
Bibliometric Approach of COVID-19 and Supply Chain Management
The supply chain and its management are the hidden engines that drive the economy. The COVID-19 pandemic has precipitated an unprecedented sustained challenge to supply chain management around the world, which has highlighted the importance of research on the effects of COVID-19 on supply chain management.
  • 1.1K
  • 30 Mar 2022
Topic Review
Computed angiotomography for Preoperative TAVR Planning
Transcatheter aortic valve replacement (TAVR) is a well-established treatment option for patients with severe symptomatic aortic stenosis (AS) whose procedural efficacy and safety have been continuously improving. Appropriate preprocedural planning, including aortic valve annulus measurements, transcatheter heart valve choice, and possible procedural complication anticipation is mandatory for a successful procedure. The gold standard for preoperative planning is still to perform a multi-detector computed angiotomography (MDCT), which provides all the information required. The planning can be performed manually, using semi-automated and automated software.
  • 1.1K
  • 23 May 2022
Topic Review
Unique Blockchain
Blockchain is an upcoming technology in the project management field, which has the potential to resolve implementation-related problems. Blockchain-based project management may increase the human life standard by reducing corruption. It also protects the project from information manipulation.
  • 1.1K
  • 26 May 2022
Topic Review
Hybrid Digital Food Twin
Food production is highly complex due to the various chemo-physical and biological processes that must be controlled to transform ingredients into final products. Further, production processes must be adapted to the variability of the ingredients, e.g., due to seasonal fluctuations of raw material quality. Digital twins are known from Industry 4.0 as a method to model, simulate, and optimize processes. Such a digital food twin has to consider the changes within the food due to micro-biological, chemical, and physical processes. Consequently, researchers propose the concept of a hybrid digital twin, which integrates simulation and data science (i.e., machine learning) to combine a data-driven perspective, simulations, and scientific models to describe the food product and the food processing process. 
  • 1.1K
  • 16 Sep 2022
Topic Review
Telomeres and Their Neighbors
Telomeres are essential structures formed from satellite DNA repeats at the ends of chromosomes in most eukaryotes. Satellite DNA repeat sequences are useful markers for karyotyping, but have a more enigmatic role in the eukaryotic cell. More research is needed until there is a complete picture of the biological function of telomere and other DNA satellite sequences, including chromatin structure, chromosome end-protection and species evolution with a particular focus on non-model organisms. The first problem to solve is the identification of telomere repeats, because telomere repeat identity is the foundation for any hypothesis about telomere maintenance and structure, or binding of specific  proteins. Celebrating Gregor Mendel’s anniversary by going to the principles behind the experiments, a selection of recent developments and underexplored areas of research from the past are illustrated in plants and insects. Indeed, much recent work has expanded beyond the human and yeast models traditional in telomere research. Classic methods from the past, and cutting-edge in silico methods are described. These do not require specialized equipment or expensive materials and can be used, often in combination, to aid research into telomeres and satellites. This can both enrich the general understanding of chromosome maintenance mechanisms and further explore the evolution of telomeres and telomerases.
  • 1.1K
  • 22 Sep 2022
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