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Topic Review
Sakai
Sakai is a free, community source, educational software platform designed to support teaching, research and collaboration. Systems of this type are also known as Course Management Systems (CMS), Learning Management Systems (LMS), or Virtual Learning Environments (VLE). Sakai is developed by a community of academic institutions, commercial organizations and individuals. It is distributed under the Educational Community License (a type of open source license). Sakai is used by hundreds of institutions, mainly in the United States , but also in Canada , Europe, Asia, Africa and Australia . Sakai was designed to be scalable, reliable, interoperable and extensible. Its largest installations handle over 100,000 users.
  • 1.1K
  • 17 Oct 2022
Topic Review
Devil's Garden (Grand Staircase-Escalante National Monument)
The Devil's Garden of the Grand Staircase-Escalante National Monument (GSENM) in south central Utah, the United States, is a protected area featuring hoodoos, natural arches and other sandstone formations. The United States Geological Survey (USGS) designated the name Devils Garden—without an apostrophe according to USGS naming conventions—on December 31, 1979. The area is also known as the Devils Garden Outstanding Natural Area within the National Landscape Conservation System. The formations in the Devils Garden were created, and continue to be shaped, by various weathering and erosional processes. These natural processes have been shaping sandstone layers formed more than 166 million years ago during the Jurassic period's Middle epoch. The Bureau of Land Management (BLM) administers the Devils Garden and the entire GSENM which is the first national monument assigned to the BLM.
  • 1.1K
  • 18 Oct 2022
Topic Review
Inversion (Meteorology)
In meteorology, an inversion is a deviation from the normal change of an atmospheric property with altitude. It almost always refers to an inversion of the air temperature lapse rate, in which case it is called a temperature inversion. Normally, air temperature decreases with an increase in altitude, but during an inversion warmer air is held above cooler air. An inversion traps air pollution, such as smog, close to the ground. An inversion can also suppress convection by acting as a "cap". If this cap is broken for any of several reasons, convection of any moisture present can then erupt into violent thunderstorms. Temperature inversion can notoriously result in freezing rain in cold climates.
  • 1.1K
  • 11 Nov 2022
Topic Review
Design Strategy for Breast Cancer Vaccine
Breast cancer has been recorded as the type of cancer that causes the highest mortality in women due to its high incidence. Given the devastating implications of the disease and the growing number of cases, many scientists and research organizations have dedicated their efforts to the fight against breast cancer. Vaccines are an upcoming medical intervention for breast cancer. By targeting the tumor antigen, cancer vaccines can be designed to train the immune system to recognize tumor cells.
  • 1.1K
  • 10 Jan 2023
Topic Review
Bioactive Compounds from Elaeodendron Genus
Elaeodendron is a genus of tiny trees, shrubs, vines, and herbs consisting of about 23 species. It is used in traditional medicine and has a wide range of pharmacological activities. From the plants in this genus, flavonoids, terpenoids, cardiac glycosides, and cardenolides have been isolated. Preclinical investigations have also revealed antiviral, anti-HIV, anticancer, antiproliferative, antioxidant, antifungal, anti-inflammation, cytotoxic, anti-plasmodial, anti-arthritic, antibacterial, and anti-diabetic activities. Bioactive substances found in Elaedendron that function in a variety of ways are related to these biological processes. 
  • 1.1K
  • 20 Feb 2023
Topic Review
Organophosphate Esters in Aquatic Environment
Organophosphate esters (OPEs) are increasingly used as flame retardants and plasticizers in various products. Most of them are physically mixed rather than chemical bonded to the polymeric products, leading to OPEs being readily released into the surrounding environment. Due to their relatively high solubility and mobility, OPEs are ubiquitous in the aquatic environment and may pose potential hazards to human health and aquatic organisms. 
  • 1.1K
  • 16 May 2023
Topic Review
Biocompatible and Biodegradable 3D Printing from Bioplastics
Three types of bioplastics are distinguished: Biodegradable bioplastics made from biobased materials. Examples include poly (lactic acid) (PLA), polyhydroxyalkanoates (PHAs), thermoplastic starch (TPS), and poly (butylene succinate) (PBS); Biodegradable bioplastics made from petrochemical resources. Examples include Poly (butylene adipate terephthalate) (PBAT) and polycaprolactone (PCL); Non-biodegradable or partially biodegradable bioplastics from biobased monomers and bioderived technical polymers. Examples are bioPE, bioPET, bioPP, and poly-trimethylene terephthalate (bioPTT).
  • 1.1K
  • 15 Jun 2023
Topic Review
Karate Women’s Embodied Subjectivities
Karate can be both a martial art and a combat sport. Male and female karate athletes attended the Tokyo Olympic Games 2020 (2021). Elite sport often portrays female athletes through the sexualization of their bodies, while the martial environment leaves them open to accusations of masculinization. In the process of constructing themselves as fighters, karateka women do produce new ways of performing femininities and masculinities, which is a hard-work process of negotiations, leading them to the construction of a particular habitus strictly linked to their performativity within the environment. They take part in a contested terrain that mixes several elements that are often contrasting.
  • 1.1K
  • 18 Oct 2023
Topic Review
CRISPR/Cas as Genome-Editing Technique in Fruit Tree Breeding
CRISPR (short for “Clustered Regularly Interspaced Short Palindromic Repeats”) is a technology that research scientists use to selectively modify the DNA of living organisms. CRISPR was adapted for use in the laboratory from the naturally occurring genome-editing systems found in bacteria.
  • 1.1K
  • 28 Nov 2023
Topic Review
Enhancing Digital Presence for Maximizing Customer Value
Digital transformation has altered the way customers interact with restaurants. As a result, digital transformation has had an enormous impact, changing restaurant customer value. Digital dynamic capabilities and digital customer orientation as a process model (i.e., sensing, seizing, transforming, and refining) to develop digital transformation and create a dynamic customer value. 
  • 1.1K
  • 15 Dec 2023
Topic Review
Sustainable Waste Management Innovations
The problem of e-waste persists given the absence of sustainable waste management innovations and policies.  We advocate for the engineering of policies that create conditions for doing more with less resources, eliminating waste, and recycling as crucial steps in creating sustainable waste management innovations.
  • 1.1K
  • 30 Jun 2021
Topic Review
Recovery of Antioxidants from Agro-Industrial Side Streams
Agro-industrial side streams covers a wide range of products available as raw materials. These can serve as a source of other added value products, under the nomenclature of biowaste. Food waste are generated from different sectors of food industry, such as vegetables, fruits, milk, meat, fish, and wine production. Recovered compounds can be re-utilized as food additives, functional foods, nutra-/pharmaceuticals, cosmeceuticals, beauty products, and bio-packaging. 
  • 1.1K
  • 20 Sep 2022
Topic Review
Halogen Hybrid Flow Batteries
Among the most effective energy systems for stationary applications, a special place is occupied by redox flow battery (RFB) technology, encompassing easy scalability with independent scaling of power density and energy capacity, no detrimental effects of a deep discharge, very low self-discharge, low cost for a large system compared to other types of batteries, and long cycle life.
  • 1.1K
  • 31 Oct 2022
Topic Review
Anti-Cancer Potential of Cinnamaldehyde
Cinnamaldehyde has anti-cancer effects through a number of different mechanisms that are interconnected with one another. These effects reduce some of the most severe symptoms of abnormally rapid cell growth. Some of the mechanistic approaches include the induction of apoptosis, cell cycle arrest, interruption in angiogenesis, free radical scavenging, inhibition of inflammation, and interference with cellular invasion and metastasis. According to the types, doses and duration of treatment of cancer, the mechanisms involved could change.
  • 1.1K
  • 13 Apr 2023
Topic Review
Monitor Mental Health Conditions
Recently, there has been an increase in the production of devices to monitor mental health and stress as means for expediting detection, and subsequent management of these conditions. The objective of this review is to identify and critically appraise the most recent smart devices and wearable technologies used to identify depression, anxiety, and stress, and the physiological process(es) linked to their detection. 
  • 1.1K
  • 11 Jun 2021
Topic Review
Human Papillomavirus Oncoproteins and Ubiquitin Proteasome System
Papillomaviridae is a diverse family of small, non-enveloped DNA viruses, approximately 50–60 nm in diameter that infect all homoeothermic vertebrates including humans. Human papillomavirus (HPV) E6 and E7 oncoproteins are critical for development and maintenance of the malignant phenotype in HPV-induced cancers. These two viral oncoproteins interfere with a plethora of cellular pathways, including the regulation of cell cycle and the control of apoptosis, which are critical in maintaining normal cellular functions. E6 and E7 bind directly with certain components of the Ubiquitin Proteasome System (UPS), enabling them to manipulate a number of important cellular pathways. 
  • 1.1K
  • 28 Apr 2022
Topic Review
PRKN Gene
parkin RBR E3 ubiquitin protein ligase
  • 1.1K
  • 22 Dec 2020
Topic Review
Emulsion Techniques
Emulsion Techniques, for example, microencapsulation and nanoencapsulation, can be used in the formulation of food coatings. A variety of methods have been developed to obtain different emulsions, forming excellent biomaterials to be applied as edible films in combination with biopolymer matrices. The significance and widespread applications of edible films to obtain coatings to protect food are originated from their unique properties, such as biocompatibility, biodegradability, and no toxicity.
  • 1.1K
  • 14 Apr 2021
Topic Review
Vertebral Fractures in HIV-Infected Patients
HIV-infected patients show high risk of fracture. The aims of our study were to determine the prevalence of vertebral fractures (VFs) and their associations with vitamin D in HIV patients. 100 patients with HIV infection and 100 healthy age- and sex-matched controls were studied. Bone mineral density was measured by quantitative ultrasound at the non-dominant heel. Serum osteocalcin and C-terminal telopeptide of collagen type 1 served as bone turnover markers. Bone ultrasound measurements were significantly lower in patients compared with controls (Stiffness Index (SI): 80.58 ± 19.95% vs. 93.80 ± 7.10%, respectively, p < 0.001). VFs were found in 16 patients and in 2 controls. HIV patients with vertebral fractures showed lower stiffness index (SI) (70.75 ± 10.63 vs. 83.36 ± 16.19, respectively, p = 0.045) and lower vitamin D levels (16.20 ± 5.62 vs. 28.14 ± 11.94, respectively, p < 0.02). The majority of VFs (87.5%) were observed in HIV-infected patients with vitamin D insufficiency, and regression analysis showed that vitamin D insufficiency was significantly associated with vertebral fractures (OR 9.15; 95% CI 0.18–0.52, p < 0.04). VFs and are a frequent occurrence in HIV-infected patients and may be associated with vitamin D insufficiency.
  • 1.1K
  • 03 Nov 2020
Topic Review
Semantic Search and SemSime
This paper presents SemSime, a semantic similarity method for searching over a setof digital resources previously annotated by means of concepts from a weighted reference ontology.It is based on a frequency approach for weighting the ontology, and refines both the user request and the annotations of the digital resources with rating scores. Such scores are High, Medium, and Low and, in the user request, indicate the preferences assigned by the user to each of the concepts representing the searching criteria whereas, in the annotations of the digital resources, they represent the levels of quality associated with each concept in describing the resources. The experiment we have performed shows that SemSime outperforms the previous semantic search method SemSim.
  • 1.1K
  • 29 Oct 2020
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