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Topic Review
Ruminant Livestock
After the Neolithic domestication at specific sites, animals colonized the world and adapted to live and produce in a variety of different environments. Molecular technologies permit to scan the genome of local livestock breeds in search of adaptive genes to be used in accelerated breeding schemes to mitigate the deleterious effects of climate change on livestock welfare and productivity.
  • 1.1K
  • 20 Oct 2021
Topic Review
Wearable Bluetooth Triage Healthcare Monitoring System
Triage is the first interaction between a patient and a nurse/paramedic. This assessment, usually performed at Emergency departments, is a highly dynamic process and there are international grading systems that according to the patient condition initiate the patient journey. Triage requires an initial rapid assessment followed by routine checks of the patients’ vitals, including respiratory rate, temperature, and pulse rate. Ideally, these checks should be performed continuously and remotely to reduce the workload on triage nurses; optimizing tools and monitoring systems can be introduced and include a wearable patient monitoring system that is not at the expense of the patient’s comfort and can be remotely monitored through wireless connectivity.
  • 1.1K
  • 14 Apr 2022
Topic Review
Polyphenols in Dental Applications
Polyphenols are a broad class of molecules extracted from plants and have a large repertoire of biological activities. Biomimetic inspiration from the effects of tea or red wine on the surface of cups or glass lead to the emergence of versatile surface chemistry with polyphenols. Owing to their hydrogen bonding abilities, coordination chemistry with metallic cations and redox properties, polyphenols are able to interact, covalently or not, with a large repertoire of chemical moieties, and can hence be used to modify the surface chemistry of almost all classes of materials.
  • 1.1K
  • 29 Mar 2022
Topic Review
Supply Chain Concentration and Corporate Environmental Responsibility
With the recent intensification of environmental problems such as the depletion of natural resources, air pollution, water pollution and shortage, and soil erosion, the balance between environmental protection and economic development has attracted worldwide attention, and both green economy and sustainable development have gradually become the future economic development directions of all countries in the world. The COVID-19 virus spread throughout the world since its discovery in late 2019. Many experts show that poor ecological environment is an important factor that affects the generation and spread of virus and the increasing mortality rates, hence stressing the importance and urgency of environmental protection. As micro-entities of national economic operation, enterprises are also subjects of natural resource consumption and ecological pollution and have an undeniable responsibility toward environmental protection. Improving the ecological environment should ultimately be integrated into the corporate environmental responsibility (CER) of firms.
  • 1.1K
  • 27 Jan 2022
Topic Review
Demographic Trends Impact Chinese Sports Industry
Demographic change is a fundamental characteristic of China’s demographic development. The primary problem in China’s population development has shifted in recent years from overall pressure to structural challenges. 
  • 1.1K
  • 07 Feb 2022
Topic Review
Mortars of the UNESCO Site of Panamá Viejo
Characterization of the mortars belonging to the UNESCO site of Panamá Viejo is here presented. The monumental site is located in Panama City (Panama) and it represents the first Spanish settlement on the Pacific Coast, founded 500 years ago, in 1519.
  • 1.1K
  • 16 May 2022
Topic Review
Extracellular Vesicle-Based Therapeutics against SARS-CoV-2
Extracellular vesicles (EVs) , comprising a variety of nano-scale vesicles ranging from 50 to 1000 nm in size, are released from all types of cells carrying a variety of lipids, proteins, and nucleic acids in a more protective manner than un-enveloped circulating biomolecules such as antibodies and cytokines from cellular DNases, RNases, proteases, and other degrading materials, due to the presence of the lipid bilayer membrane. EVs contribute to the dissemination and persistence of genetic material and proteins of SARS-CoV-2 due to the similarity in the entrance, budding, and mechanisms of biogenesis during infection. 
  • 1.1K
  • 12 Oct 2022
Topic Review
Aerobic Bioreactor Systems Treating Agro-Industrial Wastewaters
The thriving agro-industry sector accounts for an essential part of the global gross domestic product, as the need for food and feed production is rising. However, the industrial processing of agricultural products requires the use of water at all stages, which consequently leads to the production of vast amounts of effluents with diverse characteristics, which contain a significantly elevated organic content. This fact reinforces the need for action to control and minimize the environmental impact of the produced wastewater, and activated sludge systems constitute a highly reliable solution for its treatment.
  • 1.1K
  • 14 Oct 2022
Topic Review
Propellerhead Software
Reason Studios (formerly known as Propellerhead Software) is a music software company, based in Stockholm, Sweden, and founded in 1994. It produces the studio emulation Reason.
  • 1.1K
  • 04 Nov 2022
Topic Review
Proto-Circassian
Proto-Circassian (or Proto-Adyghe–Kabardian) is the reconstructed common ancestor of the Adyghean and Kabardian languages.
  • 1.1K
  • 04 Nov 2022
Topic Review
Stachybotrys chartarum Enzymes and Their Possible Applications
Stachybotrys chartarum (black mold) (Stachybotriaceae) is a toxigenic fungus that is commonly found in damp environments. This fungus has the capacity to produce various classes of bio-metabolites with unrivaled structural features, including cyclosporins, cochlioquinones, atranones, trichothecenes, dolabellanes, phenylspirodrimanes, xanthones, and isoindoline and chromene derivatives.
  • 1.1K
  • 08 Nov 2022
Topic Review
Possible Role of Kiss1/GPR54 System in Skeletal Muscle
The skeletal muscle is the storage organ for muscle glycogen and the most prominent motor organ of an organism. Consequently, the relationship between the skeletal muscle and energy metabolism cannot be ignored during physical activities, especially during exercise. The Kiss1/GPR54 system is a multifunctional genetic system with an essential role in regulating energy balance and metabolic homeostasis. Expression of Kiss1 and GPR54 mRNAs can be detected in skeletal muscle of some mammals. However, the Kiss1/GPR54 system in skeletal muscles has not been thoroughly studied. Researchers have proposed the speculation on the possible role of the kiss1 /GPRS4 system in skeletal muscle in association with exercise performance.
  • 1.1K
  • 18 Nov 2022
Topic Review
Curcumin Embedded Electrospun Nanofibers for Wound Healing
Chronic wounds impose a significant burden on individuals and healthcare systems all over the world. Through clinical and preclinical investigations, inflammation and oxidative damage have been established as the primary causes of chronic wounds. These skin sores are easily exposed to microorganisms, which in turn cause inflammation and hinder the healing process. Additionally, microorganisms may cause an infection that prevents collagen production and reepithelialization. Curcumin’s antioxidant, anti-inflammatory, and anti-infectious characteristics, among others, have been identified as useful for diabetic wound healing management. However, curcumin has a few disadvantages, such as limited bioavailability, pH-dependent instability, water insolubility, slow cell absorption, and fast intracellular metabolism. These constraints necessitates the development of a suitable transporter to improve curcumin’s stability, bioavailability, therapeutic efficacy, and solubility. 
  • 1.1K
  • 24 Nov 2022
Topic Review
Potential Role of Circadian Clock in Cancer Evolution
Circadian rhythms, including sleep/wake cycles as well as hormonal, immune, metabolic, and cell proliferation rhythms, are fundamental biological processes driven by a cellular time-keeping system called the circadian clock. Disruptions in these rhythms due to genetic alterations or irregular lifestyles cause fundamental changes in physiology, from metabolism to cellular proliferation and differentiation, resulting in pathological consequences including cancer. Cancer cells are not uniform and static but exist as different subtypes with phenotypic and functional differences in the tumor microenvironment. At the top of the heterogeneous tumor cell hierarchy, cancer stem cells (CSCs), a self-renewing and multi-potent cancer cell type, are most responsible for tumor recurrence and metastasis, chemoresistance, and mortality. Phenotypically, CSCs are associated with the epithelial-mesenchymal transition (EMT), which confers cancer cells with increased motility and invasion ability that is characteristic of malignant and drug-resistant stem cells. Recently, emerging studies of different cancer types, such as glioblastoma, leukemia, prostate cancer, and breast cancer, suggest that the circadian clock plays an important role in the maintenance of CSC/EMT characteristics.
  • 1.1K
  • 09 Dec 2022
Topic Review
Brain Natriuretic Peptide in Geriatric Heart Failure Evaluation
Heart failure is one of the main morbidity and mortality factors in the general population and especially in elderly patients. Natriuretic peptides, in particular B-type natriuretic peptide (BNP) and its fraction NTproBNP, have gained an increasingly important role in the screening, diagnosis and treatment of heart failure.
  • 1.1K
  • 16 May 2023
Topic Review
Advances in Permeation of Solutes into Hair
The permeation and absorption of solutes into human hair are highly relevant to various applications, including the formulation of hair-care products, the development of water pollution control and remediation, and the risk assessment of environmental exposure.
  • 1.1K
  • 05 Jun 2023
Topic Review
Salinity Stress Adaptive Mechanisms
Salinity stress is a major threat to the commonly grown crop cultivars. The close relatives of modern cultivated plants such as their crop wild relatives (CWRs), can be a promising and sustainable resource to broaden the diversity of crops for the salinity stress tolerances. Contemporary developments in the transcriptomic technologies have revealed the valuable genetic variation of CWRs that represents a practical gene pool for improving the plant’s adaptability to salt stress.
  • 1.1K
  • 15 Jun 2023
Topic Review
Clinical Manifestation, Pathogenesis and Diagnosis of Monkeypox Virus
Monkeypox virus is a double-stranded DNA virus species that causes disease in humans and mammals. It is a zoonotic virus belongs the genus Orthopoxviral, the family of Poxviridae, associated with the smallpox virus in many aspects. 
  • 1.1K
  • 03 Jul 2023
Topic Review
Deep Learning for Protein-Protein Interaction
Deep learning is steadily leaving its transformative imprint across multiple disciplines. Within computational biology, it is expediting progress in the understanding of Protein–Protein Interactions (PPIs), key components governing a wide array of biological functionalities.
  • 1.1K
  • 04 Jul 2023
Topic Review
Biomarkers Derived from the Molecular Profiling of TNBC
Triple-negative breast cancer (TNBC), the most aggressive and heterogenous type of cancer, lacks the expression of hormones like estrogen, progesterone, and human epidermal growth receptor-2, making chemotherapy the only treatment regimen against TNBC. To overcome the problem faced during chemotherapy, and to address the heterogeneity of TNBC, targeted therapy emerged based on the molecular profiling of TNBC. Several biomarkers are used as targets for the precision therapy in TNBC, including EGFR, VGFR, TP53, interleukins, insulin-like growth factor binding proteins, c-MET, androgen receptor, BRCA1, glucocorticoid, PTEN, ALDH1, etc.
  • 1.1K
  • 16 Aug 2023
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