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Topic Review
Physiochemical Properties of Silver Nanomaterials
Over the last decades, there has been tremendous volume of research efforts focussed on engineering silver based (nano)materials. The interest in silver has been mostly driven by the element capacity to kill pathogenic bacteria. In this context the main area of application has been medical devices that are at significant risk of becoming colonised by bacteria and infected. However, silver nanomaterials have been incorporated in a number of other commercial products which may or may not benefit from antibacterial protection. The rapid expansion of the library and their use raises important questions about possible toxicity and generally human health.
  • 1.5K
  • 28 Oct 2020
Topic Review
Magnetic nanoparticles: coating and applications
Magnetic nanoparticles (MNPs) have great potential in material science, drug delivery, magnetic resonance imaging, and therapeutic applications. Indeed, a number of iron oxide nanoparticles have been withdrawn due to their poor clinical performance and/or toxicity issues. MNPs have successfully been converted into water-soluble, stable, bio-accessible systems using the proprietary various coating strategy. Herein, we summarize the data of applications and coating strategies of MNPs.
  • 1.5K
  • 11 Jan 2022
Topic Review
TiO2-NPs: Wastewater Treatment and Ago-Environment
The tremendous increase in the production and consumption of titanium dioxide (TiO2) nanoparticles (NPs) in numerous industrial products and applications has augmented the need to understand their role in wastewater treatment technologies. The use of TiO2 NPs as the representative of photocatalytic technology for industrial wastewater treatment is coming to the horizon. As the use of industrial wastewater to feed agriculture land has been a common practice across the globe and the sewage sludge generated from wastewater treatment plants is also used as fertilizer in agricultural soils. Therefore, it is necessary to be aware of possible exposure pathways of these NPs, especially in the perspective of wastewater treatment and their impacts on the agro-environment. 
  • 1.5K
  • 11 Aug 2020
Topic Review
Vesicular Systems for Advanced Drug Delivery
Erythromycin (ERY) is a macrolide compound with a broad antimicrobial spectrum which is currently being used to treat a large number of bacterial infections affecting the skin, respiratory tract, intestines, bones and other systems, proving great value from a clinical point of view. Despite this major advantage, ERY has low water solubility and is not stable under acidic conditions which leads to a limited efficacy and bioavailability. Apart from this, higher doses promote drug resistance and undesirable effects. In order to overcome these disadvantages, during the past decades, a large variety of ERY formulations, including nanoparticles, have emerged. This work presents the preparation and performances reported for ERY vesicles, such as liposomes, ethosomes, niosomes, micelles, cubosomes and solid lipid nano(micro) particles. 
  • 1.5K
  • 19 Oct 2022
Topic Review
Multi-Walled Carbon Nanotubes-Based Sensors
Extensive use of multi-walled carbon nanotube (MWCNT) has been done for the fabrication and implementation of flexible sensors due to their enhanced electrical, mechanical, and thermal properties. These nanotubes have been deployed both in pure and composite forms for obtaining highly efficient sensors in terms of sensitivity, robustness, and longevity.
  • 1.5K
  • 17 Mar 2021
Topic Review
Zirconia
Zirconia is one of the indirect metal-free restorations used in dental medicine.
  • 1.5K
  • 01 Jun 2021
Topic Review
Phenolic Compounds of Hop Strobile Extracts
Hop (Humulus lupulus Linnaeus), a perennial plant belonging to the Cannabaceae family, has become a widely grown agricultural plant because it is used for providing bitterness and aroma to beer. Hop originated in Europe and west Asia, and are cultivated in the United States, Germany, Czech Republic, and England. Historically, the flower extracts of hop, commonly known as hops, have been used in traditional medicine for treating human health because of their sedative, anti-inflammatory, antiseptic, and antidiuretic properties. Hops are a dioecious species and unfertilized female inflorescence are commonly called cones (or strobiles). These cones are rich in unique phenolic compounds such as prenylated flavonoids, humulones (α-acids) and lupulones (β-acids).
  • 1.5K
  • 15 Feb 2022
Topic Review
Electrospun Nanofibers for Skin Tissue Engineering
Surface modification of electrospun products has been an attractive method for increasing multifunctionality and biocompatibility properties. 
  • 1.5K
  • 29 Mar 2022
Topic Review
Enzymes in/on Metal-Organic Framework Materials
The industrial use of enzymes generally necessitates their immobilization onto solid supports. The well-known high affinity of enzymes for metal-organic framework (MOF) materials, together with the great versatility of MOFs in terms of structure, composition, functionalization and synthetic approaches, has led the scientific community to develop very different strategies for the immobilization of enzymes in/on MOFs. This review focuses on one of these strategies, namely, the one-pot enzyme immobilization within sustainable MOFs, which is particularly enticing as the resultant biocomposite Enzyme@MOFs have the potential to be: (i) prepared in situ, that is, in just one step; (ii) may be synthesized under sustainable conditions: with water as the sole solvent at room temperature with moderate pHs, etc.; (iii) are able to retain high enzyme loading; (iv) have negligibleprotein leaching; and (v) give enzymatic activities approaching that given by the corresponding free enzymes. Moreover, this methodology seems to be near-universal, as success has been achieved with different MOFs, with different enzymes and for different applications. So far, the metal ions forming the MOF materials have been chosen according to their low price, low toxicity and, of course, their possibility for generating MOFs at room temperature in water, in order to close the cycle of economic, environmental and energy sustainability in the synthesis, application and disposal life cycle.
  • 1.4K
  • 16 Sep 2021
Topic Review
Biopolymers Produced by Lactic Acid Bacteria
A severe and well-known threat to the environment, the non-biodegradability of plastics obliges different stakeholders to find legislative and technical solutions for producing valuable polymers which are biodegradable and also exhibit better characteristics for packaging products. Microorganisms are recognized as exciting sources for the production of biopolymers with applications in the food industry, package production, and several other fields. Ubiquitous organisms, lactic acid bacteria (LAB) are well studied for the production of exopolysaccharides (EPS), but much less as producers of polylactic acid (PLA) and polyhydroxyalkanoates (PHAs). Based on their good biodegradability feature, as well as the possibility to be obtained from cheap biomass, PLA and PHAs polymers currently receive increased attention from both research and industry.
  • 1.4K
  • 12 Apr 2023
Topic Review
Bimetallic Nanomaterials
Bimetallic nanomaterials (BMNs) are one kind of innovative nanomaterials, referring to nano-bimetallic alloy, intermetallic compounds, or the combination of two kinds of metallic nanoparticles. Compared with monometallic nanomaterials, BMNs perform similar or even better physical and chemical properties in the medical field. BMNs possess excellent physical and chemical properties, such as easy surface modification, superior photothermal properties, multiple catalytic properties, delicate sensitivity, and good stability. Synthesis methods of bimetallic nanomaterials. The preparation methods of BMNs commonly used for cancer therapy, such as co-reduction method, hydrothermal method, seed-mediated growth method, and electrodeposition method.
  • 1.4K
  • 21 Dec 2022
Topic Review
Oxygen Reduction Reaction Catalysts Derived from Biopolymers
Due to the limited reaction rate of the oxygen reduction reaction (ORR), it is considered as a limiting factor in the performance of fuel cells and metal-air batteries. Platinum is considered the benchmark catalyst for ORR; however, the scarcity of platinum, its high price, the drift phenomenon, its insufficient durability, and its susceptibility to gas poisoning are the reasons for the constant search for new ORR catalysts. Carbon-based catalysts show exceptional promise in this respect considering economic profitability and activity, and, in addition, they have favorable conductivity and often a large specific surface area.
  • 1.4K
  • 13 Feb 2023
Topic Review
Applications of Transglutaminase
Stabilization and reusability of enzyme transglutaminase (TGM) are important goals for the enzymatic process since immobilizing TGM plays an important role in different technologies and industries. TGM can be used in many applications. Enzyme TGM gained much attention due mainly to its potential for industrial applications. In their earlier uses, TGMs focused mostly on the cheesemaking processes, mainly improving the characteristics of the cheese itself. Later on, beverage properties were being improved by decreasing viscosity and solubility increases, as well as reduction in yoghurt syneresis. Therefore, the majority of investigations of applying TGMs in different processes focused mostly on improving the functional properties of proteins that can be utilized to develop improved food ingredients, such as crosslinked milk powders and high-added food products. Such improvements were also possible due to the different immobilization techniques of TGM.
  • 1.4K
  • 16 Aug 2023
Topic Review
Stimuli-Responsive Hydrogels in Drug Delivery
Stimuli-responsive hydrogels, also known as smart hydrogels, exhibit responsiveness to diverse external stimuli. These gels can undergo reversible or irreversible changes in physical or chemical properties upon exposure to stimuli, enabling a highly controllable drug release pattern. This capability contributes to achieving precise drug administration and enhancing treatment effectiveness and safety.
  • 1.4K
  • 24 Oct 2023
Topic Review
Keratin Biomembranes
Difficulties in obtaining human nails that are large enough for examining the penetration of drug formulations led to produce keratin films regenerated from human hair. The structure, surface morphology, chemical characterization and thermal stability of the films were characterized and were compared to those of human nail, hair and bovine hoof samples using SDS-electrophoresis, SEM, XRD, FTIR and TGA. The structure of the obtained films was found to be closer to human nails than to hair or bovine hooves. The keratin films were infected with Trichophyton rubrum and were proven to be appropriate for serving as a model for studying onychomycosis.
  • 1.4K
  • 30 Oct 2020
Topic Review
Microneedles in Drug Delivery
In recent years, an innovative transdermal delivery technology has attracted great interest for its ability to distribute therapeutics and cosmeceuticals for several applications, including vaccines, drugs, and biomolecules for skin-related problems. The advantages of microneedle patch technology have been extensively evaluated in the latest literature; hence, the academic publications in this area are rising exponentially. 
  • 1.4K
  • 29 Mar 2022
Topic Review
Application and Development of Biochar in Ironmaking Production
The concept of green, low-carbon and clean energy consumption has been deeply rooted in the hearts of the people, and countries have actively advocated the use of new energy. In the face of problems such as resource shortage and environmental pollution, scholars began to explore the use of new fuels instead of coal for production. Biomass resources have the characteristics of being renewable and carbon neutral and having large output. As an energy utilization, it is helpful to promote the transformation of the energy structure in various countries. Applying it to ironmaking production is not only conducive to energy conservation and emission reduction in the ironmaking process but also can achieve efficient utilization of crop waste. 
  • 1.4K
  • 12 Nov 2023
Topic Review
Chitosan as a Biomaterial
Chitosan remarkable properties have aroused the interest of applying this material in several biomedical applications, such as tissue engineering, wound dressing, drug delivery, and cancer treatment, what has aroused the interest of this review to gather the state-of-the-art concerning this polysaccharide when used as a biomaterial, providing information about its characteristics, chemical modifications, and applications.
  • 1.4K
  • 25 Nov 2020
Topic Review
Cyclo- and Polyphosphazenes for Biomedical Applications
Cyclic and polyphosphazenes are extremely interesting and versatile substrates characterized by the presence of -P=N- repeating units. The chlorine atoms on the P atoms in the starting materials can be easily substituted with a variety of organic substituents, thus giving rise to a huge number of new materials for industrial applications. A wide variety of new phosphazene systems, either trimeric or polymeric, have been developed as biomaterials in view of different applications. The materials to apply in biomedical applications should be biocompatible.
  • 1.4K
  • 09 Dec 2022
Topic Review
Calcium Silicate-Based Materials - Antimicrobial
Endodontic materials have significantly improved dental treatment techniques in several aspects as they can be used for vital pulp treatments, as temporary root canal medication, in definitive fillings, in apical surgeries, and for regenerative procedures. Calcium silicate-based cement is a class of dental material that is used in Endodontics in direct contact with the dental structures, connective tissue, and bone. Because the material interacts with biological tissues and stimulates biomineralization processes, its properties are of major importance. The main challenge in endodontic treatments is the elimination of biofilms that are present in the root canal system anatomical complexities, as it remains even after chemical-mechanical preparation and disinfection procedures. Thus, an additional challenge for these biomaterials is to exert antimicrobial activity while maintaining their biological properties in parallel.
  • 1.4K
  • 29 Jul 2021
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