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Topic Review
Customer to Customer
Customer to customer (C2C) markets provide an innovative way to allow customers to interact with each other. Traditional markets require business to customer relationships, in which a customer goes to the business in order to purchase a product or service. In customer to customer markets, the business facilitates an environment where customers can sell goods or services to each other. Other types of markets include business to business (B2B) and business to customer (B2C). Consumer to consumer (or citizen-to-citizen) electronic commerce involves the electronically facilitated transactions between consumers through some third party. A common example is an online auction, in which a consumer posts an item for sale and other consumers bid to purchase it; the third party generally charges a flat fee or commission. The sites are only intermediaries, just there to match consumers. They do not have to check quality of the products being offered. Consumer to consumer (C2C) marketing is the creation of a product or service with the specific promotional strategy being for consumers to share that product or service with others as brand advocates based on the value of the product. The investment into conceptualising and developing a top of the line product or service that consumers are actively looking for is equitable to a retail pre-launch product awareness marketing.
  • 1.3K
  • 14 Nov 2022
Topic Review
Applications of Liquid Crystals of Cellulose Nanocrystals
Films made from cellulose nanocrystals (CNCs) may have iridescent structural colours (pure or in combination with other materials). Numerous fields might benefit from understanding how CNC self-assembly constructs these periodic structures. Some applications of cellulose nanocrystals liquid crystals are covered. 
  • 1.3K
  • 23 Nov 2022
Topic Review
Measles Induced Encephalitis
Encephalitis, a well-known complication of measles, is inflammation of the brain parenchyma which is mostly due to the viral invasion of neurons. It presents with a variety of symptoms ranging from mild to severe depending on the extent of the damaged neurons.
  • 1.3K
  • 28 Nov 2022
Topic Review
Fat Object
In geometry, a fat object is an object in two or more dimensions, whose lengths in the different dimensions are similar. For example, a square is fat because its length and width are identical. A 2-by-1 rectangle is thinner than a square, but it is fat relative to a 10-by-1 rectangle. Similarly, a circle is fatter than a 1-by-10 ellipse and an equilateral triangle is fatter than a very obtuse triangle. Fat objects are especially important in computational geometry. Many algorithms in computational geometry can perform much better if their input consists of only fat objects; see the applications section below.
  • 1.3K
  • 28 Nov 2022
Topic Review
Steroid Hormone Synthesis Inhibition by Mineralocorticoid Receptor Antagonists
Mineralocorticoid receptor antagonists (MRAs) have been found to concentration-dependently inhibit steroidogenesis in different degrees. However, many studies have proven the suppressive effects of MRAs on the activities of hormone synthase. 
  • 1.3K
  • 30 Nov 2022
Topic Review
Unc-51-like Autophagy-Activating Kinase Inhibitors as Anticancer Agents
Autophagy is a cellular process that removes damaged components of cells and recycles them as biochemical building blocks. Autophagy can also be induced to protect cells in response to intra- and extracellular stresses, including damage to cellular components, nutrient deprivation, hypoxia, and pathogenic invasion. Dysregulation of autophagy has been attributed to various diseases. In particular, autophagy protects cancer cells by supporting tumor cell survival and the development of drug resistance. The ULK complex is an early-stage regulator of autophagy and attracted particular attention as a drug target. Among ULK isoforms, ULK1, ULK2, ULK3, ULK4, and serine/threonine-protein kinase 36 (STK36), ULK1 have been most extensively studied.
  • 1.3K
  • 20 Jan 2023
Topic Review
Determination of Leaf Inclination Angle through Remote Sensing
The leaf inclination angle (LIA), defined as the leaf or needle inclination angle to the horizontal plane, is vital in radiative transfer, precipitation interception, evapotranspiration, photosynthesis, and hydrological processes. The remote sensing methods to estimate LIA are mainly based on the empirical, radiative transfer model, and gap fraction methods. More advanced inversion strategies and validation studies are necessary to improve the robustness of LIA remote sensing estimation.
  • 1.3K
  • 10 Mar 2023
Topic Review
Carbon-Based Materials for CO2 Adsorption and Conversion
The UN Climate Change Conference in Glasgow (COP26) has stressed that stakeholders need to work together to achieve a NetZero target. Technologies involving absorbents for the capture of CO2 from a gas mixture are energy-intensive. Carbon adsorption and conversion (CAC) approaches have been gaining attention since these technologies can mitigate CO2 emissions.
  • 1.3K
  • 06 Jul 2023
Topic Review
Socio-Psychological Factors on Residents’ Willingness of Waste Handling
There was a statistically significant difference between low and high levels of awareness and perceived behavior control in Dammam City households’ willingness to sort waste and recycle; however, at the middle level, there was only a significant difference in perceived behavior control. Moreover, there was a statistically significant difference between high and middle levels in government facilitators regarding sorting and recycling willingness in Dammam City.
  • 1.3K
  • 09 Oct 2023
Topic Review Peer Reviewed
Monitoring the Progress of Doctoral Students
Doctoral students, graduate students, or postgraduate researchers (PGRs) are those students who undertake a research degree culminating in a thesis of original work. In this entry-level paper, they will generally be referred to as PGRs, as this demonstrates the importance of their contribution to the global research culture. In the UK, doctorates, usually a PhD but also professional doctorates, are typically three to four years in length full-time or six years part-time and are undertaken as an individual study. Research degrees are therefore unlike undergraduate and master’s programmes as they are not taught in a classroom with other students. PGRs can therefore suffer from an isolating student experience. Student monitoring refers to systems which track PGR engagement, progress and attendance. They can therefore be used to ensure that the PGR is present on the programme and submitting work, often in accordance with pre-set deadlines. Although doctorates internationally do have many similarities, there are also significant differences. This entry manuscript will be focused on UK doctoral study, although references will be made to the international stage as appropriate.
  • 1.3K
  • 14 Mar 2025
Topic Review
Mycotoxins in Groundnuts and Tree Nuts
Mycotoxins are toxic compounds produced as secondary metabolites by certain types of filamentous fungi under specific conditions. The contamination of nuts and nut-related products with mycotoxins is a significant global concern due to their severe consequences on human health, including carcinogenicity and immunosuppression. Aflatoxins, with a particular emphasis on aflatoxin B1, are the most common and toxic mycotoxins found in human food. Aflatoxin B1 (AFB1) is known to be highly toxic and carcinogenic.
  • 1.3K
  • 19 Dec 2023
Topic Review
Lysosomal Calcium Channels
Ca2+ is pivotal intracellular messenger that coordinates multiple cell functions such as fertilization, growth, differentiation, and viability. Intracellular Ca2+ signaling is regulated by both extracellular Ca2+ entry and Ca2+ release from intracellular stores. Apart from working as the cellular recycling center, the lysosome has been increasingly recognized as a significant intracellular Ca2+ store that provides Ca2+ to regulate many cellular processes. The lysosome also talks to other organelles by releasing and taking up Ca2+. In lysosomal Ca2+-dependent processes, autophagy is particularly important, because it has been implicated in many human diseases including cancer.
  • 1.3K
  • 27 Apr 2021
Topic Review
Metformin in Pregnancy
Metformin is a first-line treatment for many people with type 2 diabetes mellitus (T2DM) and gestational diabetes mellitus (GDM) to maintain glycaemic control. Although metformin demonstrates beneficial and protective cardiovascular effects for the mother, evidence suggests metformin may not be favourable for the short and long-term metabolic health of the offspring. Metformin can cross the placenta and could have a role in fetal programming.
  • 1.3K
  • 07 Jun 2021
Topic Review
Phyto-Carbazole Alkaloids in Neuroprotection
Plant-derived (phyto) carbazole alkaloids are an important class of compounds, presented in the family of Rutaceae (Genera Murraya, Clausena, Glycosmis, Micromelum and Zanthoxylum). Due to several significant biological activities, such as antitumor, antibacterial, antiviral, antidiabetic, anti-HIV and neuroprotective activities of the parent skeleton (3-methylcarbazole), carbazole alkaloids are recognized as an important class of potential therapeutic agents. Neurodegenerative diseases (NDs) may exhibit a vast range of conditions, affecting neurons primarily and leading ultimately to the progressive losses of normal motor and cognitive functions. The main pathophysiological indicators of NDs comprise increasing atypical protein folding, oxidative stresses, mitochondrial dysfunctions, deranged neurotransmissions and neuronal losses. Phyto-carbazole alkaloids can be investigated for exerting multitarget approaches to ameliorating NDs.
  • 1.3K
  • 19 Apr 2022
Topic Review
Polyoxometalates as Electrocatalysts
Polyoxometalates (POMs) are polyatomic ions with closed 3D frameworks and unique structure containing a large number of redox active sites that make them promising electrocatalysts for electrochemical energy conversion and storage applications.
  • 1.3K
  • 09 Dec 2022
Topic Review
Crises in Antimicrobial Stewardship
Helicobacter pylori is a class I carcinogen that infects more than 100 million individuals in the United States. Antimicrobial therapy for H. pylori has typically been prescribed empirically rather than based on susceptibility testing.
  • 1.3K
  • 06 Mar 2024
Topic Review
Ovarian Damage after Low-Dose Radiation
As chemotherapy—in contrast to radiation—is mainly applied to all cancer patients, a myriad of studies already exists, which indicate that commonly used agents cause premature ovarian insufficiency (POI) by inducing the death or accelerated loss of primordial follicles as well as damage to blood vessels, stromal cells, and immune components.
  • 1.3K
  • 07 May 2022
Topic Review
Avocado–Soybean Unsaponifiables
Avocado and soybean unsaponifiables (ASU) constitute vegetable extracts made from fruits and seeds of avocado and soybean oil. Characterized by its potent anti-inflammatory effects, this ASU mixture is recommended to act as an adjuvant treatment for osteoarthritic pain and slow-acting symptomatic treatment of hip and knee osteoarthritis; autoimmune diseases; diffuse scleroderma and scleroderma-like states (e.g., morphea, sclerodactyly, scleroderma in bands). Besides, it was reported that it can improve the mood and quality of life of postmenopausal women in reducing menopause-related symptoms.
  • 1.3K
  • 24 Mar 2021
Topic Review
Experimental Pharmacotherapy for Non-Alcoholic Fatty Liver Disease
Non-alcoholic fatty liver disease (NAFLD) includes a range of chronic conditions characterized by excessive hepatic lipid accumulation, defined by the presence of steatosis in >5% of hepatocytes, in the absence of significant alcohol consumption or other causes of liver injury.
  • 1.3K
  • 14 Feb 2022
Topic Review
Measure Environmental Performance in Ports
Oceans, seas, and marine resources are highly relevant for achieving Sustainable Development Goals. Such relevance has given rise to the blue economy approach, where scholars and policymakers see activities carried out in cargo ports from a different perspective. The blue economy approach stresses the emergence of multiple transnational networks in relation to these topics and the development of green ports plus environmental performance measurements at seaports in general. 
  • 1.3K
  • 13 May 2021
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