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Topic Review
Transtheoretical Model
The transtheoretical model of behavior change is an integrative theory of therapy that assesses an individual's readiness to act on a new healthier behavior, and provides strategies, or processes of change to guide the individual. The model is composed of constructs such as: stages of change, processes of change, levels of change, self-efficacy, and decisional balance. The transtheoretical model is also known by the abbreviation "TTM" and sometimes by the term "stages of change", although this latter term is a synecdoche since the stages of change are only one part of the model along with processes of change, levels of change, etc. Several self-help books—Changing for Good (1994), Changeology (2012), and Changing to Thrive (2016)—and articles in the news media have discussed the model. It has been called "arguably the dominant model of health behaviour change, having received unprecedented research attention, yet it has simultaneously attracted criticism".
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  • 21 Oct 2022
Topic Review
Heterosis
The phenomenon of heterosis has fascinated plant breeders ever since it was first described by Charles Darwin in 1876 in the vegetable kingdom and later elaborated by George H Shull and Edward M East in maize during 1908. Heterosis is the phenotypic and functional superiority manifested in the F1 crosses over the parents. Various classical complementation mechanisms gave way to the study of the underlying potential cellular and molecular mechanisms responsible for heterosis. In cereals, such as maize, heterosis has been exploited very well, with the development of many single-cross hybrids that revolutionized the yield and productivity enhancements.
  • 5.4K
  • 29 Oct 2020
Topic Review
Towards A Comprehensive Model of Placemaking Strategy
The title deals with one of the most important issues of the current era after the fragmentation that occurred in urban design and the emergence of many dead places devoid of human presence. Its importance comes in forming a base, a checklist for the development of one of the most important components of the city, (the street), especially the commercial streets, which provide two functions at the same time. A street for movement, linking the city and meeting people's daily needs. Placemaking is an essential and promising step in creating a livable environment. The title deals with a systematic process for converting the vocabulary of previous studies into standards. The theoretical base is comprehensive for all the details of the commercial street. And by reviewing the literature, an integrated set of placemaking steps was identified as a basis for evaluating the commercial street. Accordingly, a theoretical list of dimensions was formed, and then a practical framework for placemaking strategies to form the basis for measuring livability in the commercial street. The higher the level of applying the steps of placemaking, the more livability the street. This is a summary of what the title says
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  • 24 Feb 2023
Topic Review
Pomegranate Juice Processing by Membranes
Pomegranate juice exhibits high antioxidant capacity because of its rich content of polyphenols, which represent the highest proportion of phytochemicals in pomegranate. Conventional pressure-driven membrane operations and innovative membrane operations, such as osmotic distillation and pervaporation, are discussed in relation to their potential in juice clarification, fractionation, concentration and aroma recovery. Their implementation in integrated systems offer new opportunities to improve the healthiness and quality of the juice as well as to recover, purify and concentrate bioactive compounds for the formulation of functional ingredients.
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  • 15 Jul 2020
Topic Review
List of SpaceX Starship Launches
Prototypes of the upper stage of the SpaceX Starship have been flown nine times.[lower-alpha 1] Designed and operated by private manufacturer SpaceX, the flown prototypes of Starship have been Starhopper, SN5, SN6, SN8, SN9, SN10, SN11, and SN15. Starship is planned to be a fully-reusable two-stage super heavy-lift launch vehicle and unusual for previous launch vehicle and spacecraft designs, the upper stage of Starship is intended to function both as a second stage to reach orbital velocity on launches from Earth, and also eventually be used in outer space as an on-orbit long-duration spacecraft. It is being designed to take people to Mars and beyond into the Solar System.
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  • 20 Oct 2022
Topic Review
Time Management
Time management is the process of planning and exercising conscious control of time spent on specific activities, especially to increase effectiveness, efficiency, and productivity. It involves a juggling act of various demands upon a person relating to work, social life, family, hobbies, personal interests and commitments with the finiteness of time. Using time effectively gives the person "choice" on spending/managing activities at their own time and expediency. Time management may be aided by a range of skills, tools, and techniques used to manage time when accomplishing specific tasks, projects, and goals complying with a due date. Initially, time management referred to just business or work activities, but eventually the term broadened to include personal activities as well. A time management system is a designed combination of processes, tools, techniques, and methods. Time management is usually a necessity in any project development as it determines the project completion time and scope. It is also important to understand that both technical and structural differences in time management exist due to variations in cultural concepts of time. The major themes arising from the literature on time management include the following:
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  • 04 Nov 2022
Topic Review
Yeasts in Cocoa Bean Fermentation
During the fermentation of cocoa beans, the yeasts produce volatile organic compounds (VOCs). Through reactions associated with amino acid metabolism, yeasts generate important aroma precursors as acetate esters and fatty acid ethyl esters; these are essential in developing fruity flavors and aromas in the final product (usually chocolate). In addition, some yeasts may have pectinolytic and antifungal activity, which is desirable in the post-harvest process of cocoa. The main yeast species in cocoa fermentation are Saccharomyces cerevisiae, Pichia kudriavzevii, and Hanseniaspora opuntiae. These produce higher alcohols and acetyl-CoA to make acetate–esters, compounds that produce floral and fruity notes.
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  • 19 Jul 2022
Topic Review
Sulfur Mustard
Sulfur mustard, commonly known as mustard gas, is the prototypical substance of the sulfur-based family of cytotoxic and vesicant chemical warfare agents known as the sulfur mustards, which can form large blisters on exposed skin and in the lungs. They have a long history of use as a blister-agent in warfare and along with organoarsenic compounds are the most well-studied such agents. Related chemical compounds with similar chemical structure and similar properties form a class of compounds known collectively as sulfur mustards or mustard agents. Pure sulfur mustards are colorless, viscous liquids at room temperature. When used in impure form, such as warfare agents, they are usually yellow-brown and have an odor resembling mustard plants, garlic, or horseradish, hence the name. The common name of "mustard gas" is considered inaccurate because the sulfur mustard is not actually vaporized, but dispersed as a fine mist of liquid droplets. Sulfur mustard was originally assigned the name LOST, after the scientists Wilhelm Lommel and Wilhelm Steinkopf, who developed a method of large-scale production for the Imperial German Army in 1916. Mustard agents are regulated under the 1993 Chemical Weapons Convention. Three classes of chemicals are monitored under this Convention, with sulfur and nitrogen mustard grouped in Schedule 1, as substances with no use other than in chemical warfare. Mustard agents could be deployed by means of artillery shells, aerial bombs, rockets, or by spraying from warplanes or other aircraft. Sulfur mustard can be readily decontaminated through reaction with chloramine-T.
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  • 11 Nov 2022
Topic Review
DNA Barcoding
DNA barcoding is a method of species identification using a short section of DNA from a specific gene or genes. The premise of DNA barcoding is that, by comparison with a reference library of such DNA sections (also called "sequences"), an individual sequence can be used to uniquely identify an organism to species, in the same way that a supermarket scanner uses the familiar black stripes of the UPC barcode to identify an item in its stock against its reference database. These "barcodes" are sometimes used in an effort to identify unknown species, parts of an organism, or simply to catalog as many taxa as possible, or to compare with traditional taxonomy in an effort to determine species boundaries. Different gene regions are used to identify the different organismal groups using barcoding. The most commonly used barcode region for animals and some protists is a portion of the cytochrome c oxidase I (COI or COX1) gene, found in mitochondrial DNA. Other genes suitable for DNA barcoding are the internal transcribed spacer (ITS) rRNA often used for fungi and RuBisCO used for plants. Microorganisms are detected using different gene regions. The 16S rRNA gene for example is widely used in identification of prokaryotes, whereas the 18S rRNA gene is mostly used for detecting microbial eukaryotes. These gene regions are chosen because they have less intraspecific (within species) variation than interspecific (between species) variation, which is known as the "Barcoding Gap". Some applications of DNA barcoding include: identifying plant leaves even when flowers or fruits are not available; identifying pollen collected on the bodies of pollinating animals; identifying insect larvae which may have fewer diagnostic characters than adults; or investigating the diet of an animal based on its stomach content, saliva or feces. When barcoding is used to identify organisms from a sample containing DNA from more than one organism, the term DNA metabarcoding is used, e.g. DNA metabarcoding of diatom communities in rivers and streams, which is used to assess water quality.
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  • 16 Nov 2022
Topic Review
Continuationism
Continuationism is a Christian theological belief that the gifts of the Holy Spirit have continued to the present age, specifically those sometimes called "sign gifts", such as tongues and prophecy. Continuationism is the opposite of cessationism. Continuationists believe that the miraculous gifts of the Holy Spirit are still distributed today, are still in use, and are still needed in the church. The same Holy Spirit that the Apostle Paul wrote of, claiming that it gave him supernatural abilities, was also written about in the Old Testament, which claims that it also endowed such abilities upon those whom God chose to accomplish his works, as in the New Testament. Historically, the Lutheran, Methodist, Moravian, and Pentecostal traditions of Christianity have espoused the doctrinal position of continuationism.
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  • 11 Oct 2022
Topic Review
Major Histocompatibility Complex Class II Presentation in Autoimmunity
Antigen presentation by major histocompatibility complex class II (MHC-II) molecules is crucial for eliciting an efficient immune response by CD4+ T cells and maintaining self-antigen tolerance. Some MHC-II alleles are known to be positively or negatively associated with the risk of the development of different autoimmune diseases (ADs), including those characterized by the emergence of autoreactive T cells. Apparently, the MHC-II presentation of self-antigens contributes to the autoimmune T cell response, initiated through a breakdown of central tolerance to self-antigens in the thymus. 
  • 5.4K
  • 02 Feb 2023
Topic Review Peer Reviewed
Stefan Uroš II Milutin Nemanjić (1282–1321)
King Stefan Uroš II Milutin Nemanjić (1282—Donje Nerodimlje, October 29, 1321) was a Serbian medieval king, the seventh ruler of the Serbian Nemanide dynasty, the son of King Stefan Uroš I (r. 1243–1276) and Queen Helen Nemanjić (see), the brother of the King Stefan Dragutin (r. 1276–1282) and the father of King Stefan Dečanski (r. 1322–1331). Together with his great grandfather Stefan Nemanja, the founder of the Nemanide dynasty, and his grandson, Emperor Stefan Uroš IV Dušan, King Milutin is considered the most powerful ruler of the Nemanide dynasty. The long and successful military breach of King Milutin, down the Vardar River Valley and deep into the Byzantine territories, represents the beginning of Serbian expansion into southeastern Europe, making it the dominant political power in the Balkan region in the 14th century. During that period, Serbian economic power grew rapidly, mostly because of the development of trading and mining. King Milutin founded Novo Brdo, an internationally important silver mining site. He started minting his own money, producing imitations of Venetian coins (grosso), which gradually diminished in value. This led to the ban of these coins by the Republic of Venice and provided King Milutin a place in Dante’s Divina Commedia. King Milutin had a specific philoktesia fervor: He built or renovated over three dozen Serbian Orthodox churches and monasteries not only in Serbia but also in Thessaloniki, Mt. Athos, Constantinople and The Holy Land. Over fifteen of his portraits can be found in the monumental painting ensembles of Serbian medieval monasteries as well as on two icons. 
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  • 13 Apr 2022
Topic Review
CRISPR-Cas Genome Editing Components in C. elegans
CRISPR-Cas allows us to introduce desired genome editing, including mutations, epitopes, and deletions, with unprecedented efficiency. The development of CRISPR-Cas has progressed to such an extent that it is now applicable in various fields, with the help of model organisms. C. elegans is one of the pioneering animals in which numerous CRISPR-Cas strategies have been rapidly established. Ironically, the emergence of numerous methods makes the choice of the correct method difficult. Choosing an appropriate selection or screening approach is the first step in planning a genome modification.
  • 5.4K
  • 30 Dec 2022
Topic Review
Sustainability Green Industry 4.0
The Sustainability Green Industry (SGI) 4.0 framework captures the relations of Industry 4.0, green processes and sustainability in manufacturing. The framework is structured into three vertical levels: technological, process and development, integrated through the circular economy. The SGI 4.0 framework’s purpose is to explain how Industry 4.0 technologies create sustainability outcomes through green processes. The facilitating, enabling and supporting functions of green processes allow to understand how modern technologies can be linked to the concept of sustainability. In the literature we can find various concepts connecting Industry 4.0 and sustainability, however, the key role of green processes is not mentioned.
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  • 25 Jun 2021
Topic Review
Non-Enzymatic Antioxidants
Oxidative stress has long been considered one of the pathophysiological mechanisms involved in numerous diseases, which has led to the investigation of the antioxidant systems as a promising therapy more than two decades ago. A useful antioxidant must meet specific characteristics; it must be capable of interacting with biologically relevant oxidants and free radicals; its reaction by-products should be harmless; and finally, it must reach a sufficiently high concentration in the tissue and cell compartments to ensure its activity is quantitatively relevant.
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  • 24 May 2022
Topic Review
Zwitterionics Surfactants
Zwitterions are molecules that contain both a positive and negative charge within the same molecule. They are electrically neutral as a whole, but have distinct positive and negative regions within the molecule. The most common example of a zwitterion is the amino acid molecule, which contains both a carboxyl group (-COOH) and an amino group (-NH2) within the same molecule. The carboxyl group is negatively charged at physiological pH, while the amino group is positively charged, resulting in a net charge of zero for the molecule as a whole. Zwitterions have unique properties that make them useful in various applications. They are often used as buffer solutions in biochemistry and molecular biology, as they can maintain a stable pH even when small amounts of acid or base are added. Zwitterions are also used as surfactants, due to their amphipathic nature (i.e. they have both hydrophilic and hydrophobic regions). They are used in applications such as detergents and fabric softeners, where they can help to reduce surface tension and improve the wetting and dispersibility of the product. Zwitterionic surfactants have a unique structure that allows them to interact with a wide range of substances, making them useful in various applications. The unique combination of positive and negative charges in the same molecule provides a balance that enables them to interact with both hydrophilic and hydrophobic substances, allowing them to solubilize oils and greases, emulsify water-insoluble substances, and reduce surface tension.
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  • 24 Mar 2023
Topic Review
Electrochemical Energy Storage/Conversion System
Electrochemical energy storage and conversion systems such as electrochemical capacitors, batteries and fuel cells are considered as the most important technologies proposing environmentally friendly and sustainable solutions to address rapidly growing global energy demands and environmental concerns. Their commercial applications individually or in combination of two or more devices are based on their distinguishing properties e.g., energy/power densities, cyclability and efficiencies.
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  • 03 Dec 2020
Topic Review
Newspeak
Newspeak is the language of Oceania, a fictional totalitarian state and the setting of the dystopian novel Nineteen Eighty-Four (1949), by George Orwell. To meet the ideological requirements of English Socialism (Ingsoc) in Oceania, the ruling Party created Newspeak, a controlled language of restricted grammar and limited vocabulary, meant to limit the freedom of thought—personal identity, self-expression, free will—that threatens the ideology of the régime of Big Brother and the Party, who have criminalized such concepts into thoughtcrime, as contradictions of Ingsoc orthodoxy. In "The Principles of Newspeak", the appendix to the novel, George Orwell explains that Newspeak usage follows most of the English grammar, yet is a language characterised by a continually diminishing vocabulary; complete thoughts reduced to simple terms of simplistic meaning. Linguistically, the contractions of Newspeak—Ingsoc (English Socialism), Minitrue (Ministry of Truth), etc.—derive from the syllabic abbreviations of Russian, which identify the government and social institutions of the Soviet Union, such as politburo (Politburo of the Central Committee of the Communist Party of the Soviet Union), Comintern (Communist International), kolkhoz (collective farm), and Komsomol (Young Communists' League). The long-term political purpose of the new language is for every member of the Party and society, except the Proles—the working-class of Oceania—to exclusively communicate in Newspeak, by A.D. 2050; during that 66-year transition, the usage of Oldspeak (Standard English) shall remain interspersed among Newspeak conversations. Newspeak is also a constructed language, of planned phonology, grammar, and vocabulary, like Basic English, which Orwell promoted (1942–44) during the Second World War (1939–45), and later rejected in the essay "Politics and the English Language" (1946), wherein he criticizes the bad usage of English in his day: dying metaphors, pretentious diction, and high-flown rhetoric, which produce the meaningless words of doublespeak, the product of unclear reasoning. Orwell's conclusion thematically reiterates linguistic decline: "I said earlier that the decadence of our language is probably curable. Those who deny this may argue that language merely reflects existing social conditions, and that we cannot influence its development, by any direct tinkering with words or constructions."
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  • 08 Nov 2022
Topic Review
List of Aircraft (D)
This is a list of aircraft in alphabetical order beginning with 'D'.
  • 5.4K
  • 27 Oct 2022
Topic Review
Spiking Neural Networks
Spiking neural networks (SNNs) are artificial neural network models that more closely mimic natural neural networks. In addition to neuronal and synaptic state, SNNs also incorporate the concept of time into their operating model. The idea is that neurons in the SNN do not fire at each propagation cycle (as it happens with typical multi-layer perceptron networks), but rather fire only when a membrane potential – an intrinsic quality of the neuron related to its membrane electrical charge – reaches a specific value. When a neuron fires, it generates a signal which travels to other neurons which, in turn, increase or decrease their potentials in accordance with this signal (ref).
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  • 13 Oct 2021
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